Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white to off-white powder (est) |
Heavey Metals: | <10.00 ppm |
Food Chemicals Codex Listed: | Yes |
Melting Point: | 76.00 to 78.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 285.00 to 294.00 °C. @ 760.00 mm Hg
|
Vapor Pressure: | 0.000880 mmHg @ 25.00 °C. (est) |
Flash Point: | 293.00 °F. TCC ( 145.00 °C. )
|
logP (o/w): | 1.580 |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| chloroform | | ethyl alcohol, 1gm. in 3cc of 95% alcohol at 32°F | | ethyl alcohol, 2 vol. 95% alcohol | | ethyl alcohol, 4.81 g. in 100ml. 80% propylene glycol/ 20% water by volume at 77 | | fixed oils | | glycerin | | propylene glycol | | water, 2867 mg/L @ 25 °C (est) | | water, 2820 mg/L @ 25 °C (exp) |
Insoluble in: |
| paraffin oil |
Stability: |
| cream | | hair spray | | lipstick | | lotion | | powder | | store in cool place in sealed containers |
Organoleptic Properties:
Odor Type: | vanilla |
Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
Odor Description: at 10.00 % in dipropylene glycol. | sweet creamy vanilla caramel |
Substantivity: | 400 Hour(s) |
| |
Cosmetic Information:
Safety Information:
Most important hazard(s): | Xn - Harmful. |
|
R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
Oral/Parenteral Toxicity: | |
gavage-rat LD50 [sex: M,F] > 2000 mg/kg (Jenner et al., 1964)
gavage-rat LD50 [sex: M] 4470 mg/kg (Rhône-Poulenc, Inc., 1992b)
oral-rat LD50 [sex: M,F] 3500 mg/kg Administered as a 10% solution in corn oil. (Monsanto Co., 1991a)
oral-rat LD50 [sex: M,F] 3500 mg/kg Administered as a 20% solution-suspension in corn oil. (Monsanto Co., 1991b)
gavage-rabbit LD50 2000 mg/kg (Deichmann & Kitzmiller, 1940)
intravenous-dog LDLo 760 mg/kg Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 238, Pg. 2576, 1954.
intraperitoneal-guinea pig LD50 1140 mg/kg Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 238, Pg. 2576, 1954.
intraperitoneal-mouse LD50 750 mg/kg Clinical Toxicology. Vol. 10, Pg. 61, 1977.
oral-rabbit LDLo 3000 mg/kg Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 425, 1940.
oral-rat LD50 1590 mg/kg FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 39, 1967.
|
Dermal Toxicity: | |
skin-rabbit LD50 > 7940 mg/kg National Technical Information Service. Vol. OTS0534355
subcutaneous-rat LDLo 1800 mg/kg Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 425, 1940.
|
Inhalation Toxicity: | |
Not determined
|
Safety in Use Information:
Category: | flavor and fragrance agents |
Recommendation for ethyl vanillin usage levels up to: | | 8.0000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 5400.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 43000.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 63.00000 |
beverages(nonalcoholic): | - | 20.00000 |
beverages(alcoholic): | - | 100.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | 110.00000 |
condiments / relishes: | - | - |
confectionery froastings: | 140.00000 | 200.00000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 47.00000 |
fruit ices: | - | 47.00000 |
gelatins / puddings: | - | 74.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 65.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients.View pdf |
European Food Safety Athority(efsa): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
NLM Hazardous Substances Data Bank: | Search |
Chemical Carcinogenesis Research Information System: | Search |
Cancer Citations: | Search |
Env. Mutagen Info. Center: | Search |
EPA Substance Registry Services (TSCA): | 121-32-4 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 8467 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 1 |
| 3-ethoxy-4-hydroxybenzaldehyde |
Chemidplus: | 0000121324 |
EPA/NOAA CAMEO: | hazardous materials |
RTECS: | CU6125000 for cas# 121-32-4 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
No odor group found for these |
|
| bird of paradise fragrance | FR |
acidic |
| cyclohexyl acetic acid | FL/FR |
aldehydic |
| acetyl nonyryl | FL/FR |
amber |
| cistus ladaniferus resinoid | FL/FR |
animal |
| animal carbolactone | FR |
| costus valerolactone | FR |
anise |
| anise seed oil colombia | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | anisaldehyde | FL/FR |
para- | anisaldehyde | FL/FR |
| dihydroanethol | FL/FR |
| methyl para-anisate | FL/FR |
balsamic |
2- | acetyl furan | FL/FR |
| benzoin | FL/FR |
sumatra | benzoin absolute | FL/FR |
siam | benzoin absolute | FL/FR |
| benzoin absolute replacer | FL/FR |
sumatra | benzoin gum | FL/FR |
siam | benzoin resin | FL/FR |
sumatra | benzoin resin | FL/FR |
| benzoin resin replacer | FR |
sumatra | benzoin resinoid | FL/FR |
siam | benzoin resinoid | FL/FR |
1- | benzoyl acetone | FL/FR |
| benzyl cinnamate | FL/FR |
iso | butyl cinnamate | FL/FR |
| cinnamyl alcohol | FL/FR |
| ethyl cinnamate | FL/FR |
| fir balsam absolute | FR |
| guaiacyl phenyl acetate | FL/FR |
| methyl cinnamate | FL/FR |
| peru balsam absolute | FL/FR |
| peru balsam oil | FL/FR |
| peru balsam resinoid | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
berry |
| raspberry ketone | FL/FR |
| raspberry ketone acetate | FL/FR |
| raspberry ketone methyl ether | FL/FR |
bready |
| coffee furanone | FL/FR |
buttery |
| acetoin | FL/FR |
| acetyl butyryl | FL/FR |
| acetyl isobutyryl | FL/FR |
| acetyl propionyl | FL/FR |
| butyl butyryl lactate | FL/FR |
3,4- | hexane dione | FL/FR |
2-oxo | butyric acid | FL/FR |
| caramel furanone solution | FL/FR |
| caramel pentadione | FL/FR |
| coffee dione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
| fenugreek absolute | FL/FR |
| geranyl crotonate | FR |
| immortelle absolute | FL/FR |
| levulinic acid | FL/FR |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
| menthone lactone | FL/FR |
| mesitene lactone | FR |
5- | methyl furfural | FL/FR |
| rosefuran | FL/FR |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
| toffee furanone | FL/FR |
cheesy |
| butyric acid | FL/FR |
chemical |
| styralyl alcohol | FL/FR |
chocolate |
iso | amyl phenyl acetate | FL/FR |
| chocolate specialty | FR |
| vanillyl ethyl ether | FL/FR |
citrus |
blood | orange oil italy | FL/FR |
sweet | orange peel oil c.p. brazil | FL/FR |
coconut |
alpha- | angelica lactone | FL/FR |
| coconut decanone methyl | FR |
delta- | decalactone | FL/FR |
delta-2- | dodecenolactone | FL/FR |
gamma- | heptalactone | FL/FR |
delta- | nonalactone | FL/FR |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
gamma- | octalactone | FL/FR |
delta- | undecalactone | FL/FR |
coumarinic |
| coumane | FL/FR |
| tonka bean resinoid | FR |
creamy |
| butyl lactate | FL/FR |
gamma- | butyrolactone | FL/FR |
| creamy lactone | FL/FR |
| cyclotene propionate | FL/FR |
| geranyl ethyl acetal | FR |
3- | heptyl dihydro-5-methyl-2(3H)-furanone | FL/FR |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
earthy |
1- | nonen-3-ol | FL/FR |
ethereal |
| ethyl 4-pentenoate | FL/FR |
| ethyl pyruvate | FL/FR |
iso | valeraldehyde propylene glycol acetal | FL/FR |
fatty |
(Z)- | dairy lactone | FL/FR |
| ethyl undecylenate | FL/FR |
4- | methyl octanoic acid | FL/FR |
fermented |
| butyl laevo-lactate | FL/FR |
| ethyl (E)-2-crotonate | FL/FR |
floral |
| acetophenone | FL/FR |
| coffee flower absolute | FR |
para- | cresyl laurate | FL/FR |
| cyclohexyl ethyl alcohol | FL/FR |
alpha- | damascone | FL/FR |
| dihydrojasmone | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| ethyl phenyl acetate | FL/FR |
| floral pyranol | FR |
| heliotropin | FL/FR |
| heliotropyl acetate | FL/FR |
| heliotropyl acetone | FL/FR |
| heliotropyl diethyl acetal | FR |
| hyacinth ether | FR |
para- | methyl acetophenone | FL/FR |
| methyl dihydrojasmonate | FL/FR |
beta- | naphthyl methyl ketone | FL/FR |
| nerolidol | FL/FR |
| peony alcohol | FR |
| phenethyl acetate | FL/FR |
| phenethyl alcohol | FL/FR |
| phenethyl isobutyrate | FL/FR |
| phenethyl phenyl acetate | FL/FR |
| rose butanoate | FL/FR |
| violet methyl carbonate | FR |
fruity |
| acetoin acetate | FL/FR |
para- | anisyl propionate | FL/FR |
| artemisia pallens herb oil | FL/FR |
beta- | damascone | FL/FR |
gamma- | decalactone | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
(E)- | ethyl tiglate | FL/FR |
| farnesyl acetone | FL/FR |
| guaiacyl propionate | FL/FR |
| methyl (Z)-5-octenoate | FL/FR |
| octyl butyrate | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| vanilla carboxylate | FL/FR |
green |
iso | amyl 3-(2-furan) propionate | FL/FR |
iso | butyl benzyl carbinol | FL/FR |
(Z)-4- | hepten-1-ol | FL/FR |
(Z)-4- | heptenal | FL/FR |
(Z)-4- | heptenal diethyl acetal | FL/FR |
(Z)-3- | hexen-1-yl propionate | FL/FR |
| hexyl 2-methyl butyrate | FL/FR |
| violet leaf absolute | FL/FR |
hay |
| beeswax absolute | FL/FR |
| hay absolute | FR |
herbal |
| butyl levulinate | FL/FR |
honey |
| methyl phenyl acetate | FL/FR |
| phenyl acetic acid | FL/FR |
licorice |
(E)- | anethol | FL/FR |
melon |
(Z)-6- | nonenal | FL/FR |
| watermelon ketone | FR |
milky |
laevo- | glutamine | CS |
minty |
laevo- | carvone | FL/FR |
| menthoxypropane diol | FL/FR |
| vanillin menthoxypropane diol acetal | FL/FR |
mossy |
| veramoss (IFF) | FR |
mushroom |
3- | octen-2-ol | FL/FR |
musk |
| ethylene brassylate | FL/FR |
omega- | pentadecalactone | FL/FR |
musty |
3- | acetyl-2,5-dimethyl furan | FL/FR |
naphthyl |
2,4- | dimethyl benzaldehyde | FL/FR |
para- | methyl anisole | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
nutty |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
2,3- | dimethyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| resorcinol | FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
phenolic |
| ethyl vanillate | FL/FR |
ortho- | guaiacol | FL/FR |
4- | methyl-2,6-dimethoxyphenol | FL/FR |
popcorn |
2- | acetyl pyrazine | FL/FR |
powdery |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
2,6- | dimethoxyphenol | FL/FR |
alpha- | ethoxy-ortho-cresol | FL/FR |
spicy |
| allspice oil | FL/FR |
para- | anisyl formate | FL/FR |
| benzyl isoeugenol | FL/FR |
| cassia bark oil china | FL/FR |
| clove bud oil | FL/FR |
| dianthus ethone | FR |
4- | ethyl guaiacol | FL/FR |
iso | eugenyl acetate | FL/FR |
3-(2- | furyl) acrolein | FL/FR |
(E)-para- | methoxycinnamaldehyde | FL/FR |
para- | methoxycinnamaldehyde | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
4- | methyl guaiacol | FL/FR |
| methyl isoeugenol | FL/FR |
cis- | oak lactone | |
| spicy acetoacetate | FL/FR |
| zingerone | FL/FR |
sweet |
| tonka bean absolute replacer | FR |
| vanilla bean absolute (vanilla spp.) | FL/FR |
| vanilla oleoresin bali | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanilla resinoid | FL/FR |
| vanilla tahitensis fruit absolute | FR |
| vanilla tahitensis fruit absolute CO2 extract | FL/FR |
| vanilla tahitensis fruit extract | FL/FR |
| vanilla tahitensis fruit oil CO2 extract | FR |
tonka |
6- | amyl-alpha-pyrone | FL/FR |
| coumarin | FR |
gamma- | hexalactone | FL/FR |
| mint lactone | FL/FR |
| octahydrocoumarin | FL/FR |
| tonka bean absolute | FR |
tropical |
| curcuma amada roxb. rhizome oil CO2 extract | FL/FR |
vanilla |
| acetovanillone | FL/FR |
| crème brulee fragrance | FR |
ortho- | dimethyl hydroquinone | FL/FR |
| ethyl vanillin acetate | FR |
| ethyl vanillin diethyl acetal | FR |
| ethyl vanillin hexylene glycol acetal | FR |
| ethyl vanillin isobutyrate | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
| heliotropyl alcohol | FL/FR |
| methyl vanillate | FL/FR |
| propenyl guaethol | FL/FR |
iso | propyl vanillin | |
| vanilla | FR |
| vanilla aromatica fruit extract | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanilla bean absolute CO2 extract (vanilla planifolia) | FL/FR |
| vanilla bean fragrance | FR |
| vanilla bean oil (vanilla planifolia) | FR |
| vanilla bean oil (vanilla tahitensis) | FL/FR |
| vanilla bean oil CO2 extract | FL/FR |
| vanilla bean tincture | FR |
| vanilla cresol | FR |
| vanilla extract | FL/FR |
country | vanilla fragrance | FR |
| vanilla fragrance | FR |
french | vanilla fragrance | FR |
| vanilla planifolia fruit extract | FL/FR |
| vanilla planifolia fruit infusion | FR |
| vanilla planifolia fruit water | FL/FR |
| vanilla specialty | FR |
| vanillin | FL/FR |
| vanillin 2,3-butylene glycol acetal | FL/FR |
| vanillin hexylene glycol acetal | FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl butyl ether | FL/FR |
| vanillyl isobutyrate | FL/FR |
| vanillylidene acetone | FL/FR |
vegetable |
| methional | FL/FR |
| tetrahydrofurfuryl alcohol | FL/FR |
waxy |
| allyl nonanoate | FL/FR |
| ethyl palmitate | FL/FR |
| methyl laurate | FL/FR |
2- | nonanol | FL/FR |
| octyl isobutyrate | FL/FR |
delta- | tetradecalactone | FL/FR |
| undecanoic acid | FL/FR |
woody |
| guaiacwood extract acetate | FR |
| guaiacwood oil | FL/FR |
| guaiacyl acetate | FL/FR |
| gurjun balsam oil | FR |
4- | hydroxybenzaldehyde | FL/FR |
| patchouli ethanone | FR |
| patchouli oil | FL/FR |
| sandal pentanol | FR |
| santall | FR |
| tobacarol (IFF) | FR |
| vetiver oil haiti | FL/FR |
|
For Flavor |
|
No flavor group found for these |
2- | acetyl-3,4,5,6-tetrahydropyridine | FL |
| allyl 2-furoate | FL |
| allyl methyl trisulfide | FL |
para- | anisyl propionate | FL/FR |
| benzoin | FL/FR |
1- | benzoyl acetone | FL/FR |
| benzyl disulfide | FL |
| cistus ladaniferus resinoid | FL/FR |
| coumane | FL/FR |
| cyclotene propionate | FL/FR |
6- | decenoic acid | FL |
2,5- | diethyl tetrahydrofuran | FL |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
ortho- | dimethyl hydroquinone | FL/FR |
delta-2- | dodecenolactone | FL/FR |
alpha- | ethoxy-ortho-cresol | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl 4-pentenoate | FL/FR |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
| farnesyl acetone | FL/FR |
| furfuryl acetone | FL |
3-(2- | furyl) acrolein | FL/FR |
| glucoethyl vanillin | FL |
| glucovanillin | FL |
| guaiacyl propionate | FL/FR |
| heliotropyl alcohol | FL/FR |
| menthone lactone | FL/FR |
| menthoxypropane diol | FL/FR |
(E)-para- | methoxycinnamaldehyde | FL/FR |
4- | methoxysalicylaldehyde | FL |
| methyl para-anisate | FL/FR |
| methyl vanillate | FL/FR |
cis- | oak lactone | |
iso | propyl vanillin | |
| rosefuran | FL/FR |
| vanilla tahitensis fruit absolute CO2 extract | FL/FR |
| vanillin menthoxypropane diol acetal | FL/FR |
| vanillyl butyl ether | FL/FR |
| vanilmandelic acid | FL |
|
iso | amyl 3-(2-furan) propionate | FL/FR |
beta- | damascone | FL/FR |
acidic |
| levulinic acid | FL/FR |
aldehydic |
| acetyl nonyryl | FL/FR |
amber |
iso | butyl benzyl carbinol | FL/FR |
anise |
(E)- | anethol | FL/FR |
| anise seed oil colombia | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | anisaldehyde | FL/FR |
balsamic |
| benzoin absolute replacer | FL/FR |
sumatra | benzoin gum | FL/FR |
siam | benzoin resin | FL/FR |
sumatra | benzoin resin | FL/FR |
siam | benzoin resinoid | FL/FR |
sumatra | benzoin resinoid | FL/FR |
iso | butyl cinnamate | FL/FR |
| ethyl cinnamate | FL/FR |
| peru balsam | FL |
| peru balsam absolute | FL/FR |
| peru balsam oil | FL/FR |
| peru balsam resinoid | FL/FR |
| vanillylidene acetone | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone | FL/FR |
| raspberry ketone acetate | FL/FR |
| raspberry ketone methyl ether | FL/FR |
bready |
| mango furanone | FL |
2- | propionyl thiazole | FL |
brown |
| beeswax absolute | FL/FR |
2-oxo | butyric acid | FL/FR |
5- | methyl furfural | FL/FR |
| tetrahydrofurfuryl acetate | FL/FR |
burnt |
| furfuryl alcohol | FL |
buttery |
| butter cream frosting flavor | FL |
| butter nut vanilla flavor | FL |
| butter vanilla nut flavor | FL |
| butyl laevo-lactate | FL/FR |
| diacetyl | FL |
3,4- | hexane dione | FL/FR |
cabbage |
| methyl 2-thiofuroate | FL |
caramellic |
| caramel furanone | FL |
| caramel furanone solution | FL/FR |
| caramel malted mambo flavor | FL |
| caramel pentadione | FL/FR |
| creme brulee flavor | FL |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
| ethyl furaneol | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-3,4,5,6-tetramethyl cyclohexen-2-one | FL |
| fenugreek absolute | FL/FR |
| lucuma flavor | FL |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple cream flavor | FL |
| maple furanone | FL/FR |
3- | methyl butyl 2-furyl butyrate | FL |
| pyruvaldehyde | FL |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| strawberry furanone acetate | FL/FR |
| strawberry furanone solution | FL/FR |
| toffee furanone | FL/FR |
chemical |
| styralyl alcohol | FL/FR |
cherry |
| heliotropin | FL/FR |
para- | methoxycinnamaldehyde | FL/FR |
citrus |
blood | orange oil italy | FL/FR |
sweet | orange peel oil c.p. brazil | FL/FR |
coconut |
delta- | decalactone | FL/FR |
(R)- | massoia lactone | FL |
6- | methyl coumarin | FL |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| octahydrocoumarin | FL/FR |
coffee |
| coffee creme brulee flavor | FL |
| coffee dione | FL/FR |
2- | thiophene thiol | FL |
corn chip |
2- | acetyl-2-thiazoline | FL |
creamy |
| acetoin | FL/FR |
| acetyl butyryl | FL/FR |
| acetyl isobutyryl | FL/FR |
6- | amyl-alpha-pyrone | FL/FR |
alpha- | angelica lactone | FL/FR |
para- | anisaldehyde | FL/FR |
| butyl butyryl lactate | FL/FR |
| creamy lactone | FL/FR |
| dihydrocoumarin | FL |
| divanillin | FL |
| ethyl vanillate | FL/FR |
gamma- | hexalactone | FL/FR |
4- | hydroxybenzaldehyde | FL/FR |
para- | methyl acetophenone | FL/FR |
| mint lactone | FL/FR |
delta- | nonalactone | FL/FR |
| octyl isobutyrate | FL/FR |
delta- | undecalactone | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
dairy |
| butyl lactate | FL/FR |
| creme brulle coffee flavor | FL |
| methyl (Z)-5-octenoate | FL/FR |
earthy |
1- | nonen-3-ol | FL/FR |
eggy |
| egg nog creme brulee flavor | FL |
fatty |
(Z)- | dairy lactone | FL/FR |
| diacetyl trimer | FL |
| ethyl undecylenate | FL/FR |
4- | methyl octanoic acid | FL/FR |
2,4- | octadien-1-ol | FL |
(E,E)-2,4- | undecadienal | FL |
2,4- | undecadienal | FL |
floral |
iso | amyl phenyl acetate | FL/FR |
| dihydrojasmone | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| heliotropyl acetate | FL/FR |
| methyl dihydrojasmonate | FL/FR |
| methyl phenyl acetate | FL/FR |
beta- | naphthyl methyl ketone | FL/FR |
| phenethyl alcohol | FL/FR |
| phenyl acetic acid | FL/FR |
fruity |
| acetoin acetate | FL/FR |
| acetyl isovaleryl | FL |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
| artemisia pallens herb oil | FL/FR |
alpha- | damascone | FL/FR |
gamma- | decalactone | FL/FR |
| ethyl 3-oxohexanoate | FL |
| ethyl methyl-para-tolyl glycidate | FL/FR |
(E)- | ethyl tiglate | FL/FR |
| furfuryl valerate | FL |
3- | heptyl dihydro-5-methyl-2(3H)-furanone | FL/FR |
(E,E)- | methyl sorbate | FL |
2- | pentanoyl furan | FL |
| rose butanoate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
iso | valeraldehyde propylene glycol acetal | FL/FR |
| vanilla carboxylate | FL/FR |
green |
| cinnamyl alcohol | FL/FR |
| cyclohexyl ethyl alcohol | FL/FR |
| heptanal 2,3-butane diol acetal | FL |
(Z)-4- | hepten-1-ol | FL/FR |
(Z)-4- | heptenal | FL/FR |
(Z)-4- | heptenal diethyl acetal | FL/FR |
(Z)-3- | hexen-1-yl propionate | FL/FR |
| hexyl 2-methyl butyrate | FL/FR |
| immortelle absolute | FL/FR |
| nerolidol | FL/FR |
(Z)-6- | nonenal | FL/FR |
| violet leaf absolute | FL/FR |
herbal |
| butyl levulinate | FL/FR |
| dihydroanethol | FL/FR |
5- | hydroxymethyl furfural | FL |
honey |
| ethyl phenyl acetate | FL/FR |
| phenethyl acetate | FL/FR |
| phenethyl isobutyrate | FL/FR |
| phenethyl phenyl acetate | FL/FR |
jammy |
| ethyl cyclopentenolone | FL/FR |
lactonic |
gamma- | heptalactone | FL/FR |
gamma- | octalactone | FL/FR |
meaty |
4- | allyl-2,6-dimethoxyphenol | FL |
medicinal |
2,6- | dimethoxyphenol | FL/FR |
milky |
gamma- | butyrolactone | FL/FR |
minty |
laevo- | carvone | FL/FR |
mushroom |
3- | octen-2-ol | FL/FR |
musk |
| ethylene brassylate | FL/FR |
musty |
| ethyl (E)-2-crotonate | FL/FR |
naphthyl |
2,4- | dimethyl benzaldehyde | FL/FR |
para- | methyl anisole | FL/FR |
nutty |
2- | acetyl furan | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| coffee furanone | FL/FR |
2,3- | dimethyl pyrazine | FL/FR |
| furfural acetone | FL |
| nutty cyclohexenone | FL/FR |
| peanut oxazole | FL |
| tetrahydrofurfuryl alcohol | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
phenolic |
| guaiacyl phenyl acetate | FL/FR |
4- | methyl-2,6-dimethoxyphenol | FL/FR |
powdery |
| acetophenone | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
| powdery ketone | FL |
roasted |
2- | acetyl pyrazine | FL/FR |
rummy |
| ethyl pyruvate | FL/FR |
| vanillyl ethyl ether | FL/FR |
sour |
| butyric acid | FL/FR |
spicy |
| allspice oil | FL/FR |
para- | anisyl formate | FL/FR |
siam | benzoin absolute | FL/FR |
sumatra | benzoin absolute | FL/FR |
| benzyl cinnamate | FL/FR |
| benzyl isoeugenol | FL/FR |
| benzylidene acetone | FL |
| cassia bark oil china | FL/FR |
| clove bud oil | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl cinnamate | FL/FR |
| methyl isoeugenol | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
| root beer float flavor | FL |
| spicy acetoacetate | FL/FR |
chai | vanilla flavor | FL |
| zingerone | FL/FR |
sweet |
| caramel dione | FL |
| cyclohexyl acetic acid | FL/FR |
| ethyl 3-(2-hydroxyphenyl) propionate | FL |
| molasses flavor | FL |
| orange vanilla cream flavor | FL |
| vanilla bean absolute (vanilla spp.) | FL/FR |
| vanilla bean aromatica | FL |
| vanilla bean planifolia | FL |
| vanilla butter nut flavor | FL |
| vanilla concentrate | FL |
| vanilla oleoresin bali | FL/FR |
| vanilla oleoresin bourbon | FL/FR |
| vanilla resinoid | FL/FR |
| vanilla tahitensis fruit extract | FL/FR |
toasted |
| acetyl propionyl | FL/FR |
tomato |
| methional | FL/FR |
tropical |
| curcuma amada roxb. rhizome oil CO2 extract | FL/FR |
vanilla |
| acetovanillone | FL/FR |
vanilla | chai flavor | FL |
| ethyl vanillin isobutyrate | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
vanilla | ice cream flavor | FL |
4- | methyl guaiacol | FL/FR |
omega- | pentadecalactone | FL/FR |
| propenyl guaethol | FL/FR |
| vanilla aromatica fruit extract | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanilla bean absolute CO2 extract (vanilla planifolia) | FL/FR |
| vanilla bean flavor key | FL |
| vanilla bean oil (vanilla tahitensis) | FL/FR |
| vanilla bean oil CO2 extract | FL/FR |
| vanilla bean paste | FL |
| vanilla bean powder | FL |
| vanilla bean tahitensis | FL |
| vanilla distillates | FL |
| vanilla extract | FL/FR |
bourbon | vanilla flavor | FL |
bakers white | vanilla flavor | FL |
french | vanilla flavor | FL |
| vanilla flavor | FL |
| vanilla flavor key | FL |
| vanilla hazelnut flavor | FL |
| vanilla macadamia nut flavor | FL |
| vanilla nut creme flavor | FL |
| vanilla pandan flavor | FL |
| vanilla planifolia fruit extract | FL/FR |
| vanilla planifolia fruit water | FL/FR |
| vanilla powder flavor | FL |
| vanilla swirl flavor | FL |
| vanillin | FL/FR |
| vanillin 2,3-butylene glycol acetal | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl isobutyrate | FL/FR |
waxy |
| allyl nonanoate | FL/FR |
para- | cresyl laurate | FL/FR |
| ethyl palmitate | FL/FR |
| furfuryl octanoate | FL |
| methyl laurate | FL/FR |
2- | nonanol | FL/FR |
| octyl 2-furoate | FL |
| octyl butyrate | FL/FR |
delta- | tetradecalactone | FL/FR |
| undecanoic acid | FL/FR |
woody |
4- | ethyl guaiacol | FL/FR |
ortho- | guaiacol | FL/FR |
| guaiacwood oil | FL/FR |
| guaiacyl acetate | FL/FR |
| patchouli oil | FL/FR |
| vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| bourbonal | | ethavan | | ethovan | 3- | ethoxy protocatechualdehyde | 2- | ethoxy-4-formyl phenol | 3- | ethoxy-4-hydroxy-benzaldehyde | 3- | ethoxy-4-hydroxybenzaldehyde | 3- | ethoxy-4-oxidanyl-benzaldehyde | 3- | ethoxyprotocatechualdehyde | | ethyl protal | | ethyl protocatechualdehyde-3-ethyl ether | | ethyl protocatechuic aldehyde | | ethyl vanillin 10% dpg | | ethyl vanillin FCC | | ethyl vanillin N.F. | | ethyl vanillin NF | | ethyl vanillin synthetic | | ethylprotal | | ethylprotocatechualdehyde-3-ethyl ether | | ethylprotocatechuic aldehyde | | ethylvanillin | 4- | hydroxy-3-ethoxybenzaldehyde | | protocatechuic aldehyde ethyl ether | | quantrovanil | | rhodiarome | | rhodiascent | | vanillin, ethyl- | | vanirome |
Articles:
PubMed: | Determination of flavor enhancers in milk powder by one-step sample preparation and two-dimensional liquid chromatography. |
J-Stage: | Antioxidant Properties of Ethyl Vanillin in Vitro and in Vivo |
PubMed: | Laccase catalyzed synthesis of iodinated phenolic compounds with antifungal activity. |
PubMed: | A vanillin derivative causes mitochondrial dysfunction and triggers oxidative stress in Cryptococcus neoformans. |
PubMed: | Determination of vanillin, ethyl vanillin, and coumarin in infant formula by liquid chromatography-quadrupole linear ion trap mass spectrometry. |
PubMed: | The missense of smell: functional variability in the human odorant receptor repertoire. |
PubMed: | Oxidative decarboxylation of mandelic acid derivative by recombinant Escherichia coli: a novel method of ethyl vanillin synthesis. |
PubMed: | A systematic approach for optimizing the robustness of pulse sequence elements with respect to couplings, offsets, and B1-field inhomogeneities (COB). |
PubMed: | Phenolic compounds in particles of mainstream waterpipe smoke. |
PubMed: | Thermal tolerance and survival of Cronobacter sakazakii in powdered infant formula supplemented with vanillin, ethyl vanillin, and vanillic acid. |
PubMed: | Effect of vanillin and ethyl vanillin on cytochrome P450 activity in vitro and in vivo. |
PubMed: | Molecularly imprinted photonic hydrogels as colorimetric sensors for rapid and label-free detection of vanillin. |
PubMed: | Effect of vanillin, ethyl vanillin, and vanillic acid on the growth and heat resistance of Cronobacter species. |
PubMed: | Antioxidant properties of ethyl vanillin in vitro and in vivo. |
PubMed: | Differential presence of anthropogenic compounds dissolved in the marine waters of Puget Sound, WA and Barkley Sound, BC. |
PubMed: | Simultaneous spectrophotometric kinetic determination of four flavor enhancers in foods with the aid of chemometrics. |
PubMed: | A comprehensive evaluation of the toxicology of cigarette ingredients: aromatic carbonyl compounds. |
PubMed: | Synthesis and anticancer activity of some novel tetralin-6-yl-pyrazoline, 2-thioxopyrimidine, 2-oxopyridine, 2-thioxo-pyridine and 2-iminopyridine derivatives. |
PubMed: | [Studies on the chemical constituents of marine sponge Iotrochota sp]. |
PubMed: | Conformational equilibria in vanillin and ethylvanillin. |
PubMed: | Assessment of the anti-angiogenic, anti-inflammatory and antinociceptive properties of ethyl vanillin. |
PubMed: | Microencapsulation of flavors in carnauba wax. |
PubMed: | Fast single run of vanilla fingerprint markers on microfluidic-electrochemistry chip for confirmation of common frauds. |
PubMed: | Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. |
PubMed: | Rapid method for the determination of coumarin, vanillin, and ethyl vanillin in vanilla extract by reversed-phase liquid chromatography with ultraviolet detection. |
PubMed: | Dihydroagarofuranoid sesquiterpenes, a lignan derivative, a benzenoid, and antitubercular constituents from the stem of Microtropis japonica. |
PubMed: | Competitive and noncompetitive odorant interactions in the early neural coding of odorant mixtures. |
PubMed: | 3-Eth-oxy-4-hydroxy-benzaldehyde. |
PubMed: | Synthesis and non-aqueous medium titrations of some new 4-benzylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives. |
PubMed: | Rapid sample screening method for authenticity controlling vanilla flavors using a CE microchip approach with electrochemical detection. |
PubMed: | Optical recording of the intrinsic signal from the human olfactory cleft. |
PubMed: | Determination of coumarin, vanillin, and ethyl vanillin in vanilla extract products: liquid chromatography mass spectrometry method development and validation studies. |
PubMed: | Electrophysiological and behavioral responses to chocolate volatiles in both sexes of the pyralid moths Ephestia cautella and Plodia interpunctella. |
PubMed: | Qualitative determination of false-positive effects in the acetylcholinesterase assay using thin layer chromatography. |
PubMed: | Optimum methamphetamine profiling with sample preparation by solid-phase microextraction. |
PubMed: | Identification of impurities and statistical classification of methamphetamine tablets (Ya-Ba) seized in Thailand. |
PubMed: | Human potency predictions for aldehydes using the local lymph node assay. |
PubMed: | Liquid chromatographic determination of vanillin and related aromatic compounds. |
PubMed: | Odor response properties of rat olfactory receptor neurons. |
PubMed: | Identification of coumarin as the sensitizer in a patient sensitive to her own perfume but negative to the fragrance mix. |
PubMed: | Odorants selectively activate distinct G protein subtypes in olfactory cilia. |
PubMed: | Specificity of signal molecules in the activation of Agrobacterium virulence gene expression. |
PubMed: | Determination of coumarin as an adulterant in vanilla flavoring products by high-performance liquid chromatography. |
PubMed: | Identification of urinary 3-ethoxy-4-hydroxybenzoic and 3-ethoxy-4-hydroxymandelic acids after dietary intake of ethyl vanillin. |
PubMed: | Immediate reactions to balsam of Peru, cassia oil and ethyl vanillin. |
PubMed: | Determination of vanillin and ethyl vanillin in food products. |
PubMed: | [On the polarographic and oscillopolarographic determination of the semicarbazones of vanillin and ethyl vanillin (IV)]. |
PubMed: | Anti-tuberculosis agents derived from 3-ethoxy-4-hydroxybenzaldehyde. |
PubMed: | [Differential subject for the correction of vanillin and ethyl vanillin]. |
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