Category:flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | yellow to tan powder (est) |
Assay: | 97.00 to 100.00
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Food Chemicals Codex Listed: | No |
Melting Point: | 116.00 to 118.00 °C. @ 760.00 mm Hg
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Boiling Point: | 310.00 to 311.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.017000 mmHg @ 25.00 °C. (est) |
Flash Point: | 214.00 °F. TCC ( 101.11 °C. )
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logP (o/w): | 1.350 |
Soluble in: |
| alcohol | | water, 2.635e+004 mg/L @ 25 °C (est) | | water, 8450 mg/L @ 25 °C (exp) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Type: woody |
sweet nutty almond balsamic woody |
Odor Description:at 100.00 %. sweet nutty almond balsam woody |
nutty almond balsamic vanilla brown honey metallic |
Odor Description:at 1.00 %. slightly nutty almond, balsamic vanilla like with slight brown honey nuance. with a faint metallic character Mosciano, Gerard, (2009) |
Flavor Type: creamy |
creamy musty nutty vanilla honey |
Taste Description: at 10.00 ppm. mparts a creamy mouth feel, slightly musty nutty with vanilla and honey nuances Mosciano, Gerard, (2009) |
Odor and/or flavor descriptions from others (if found). |
Prodasynth |
PARA-HYDROXYBENZOIC ALDEHYDE (> 98%) |
Odor Description:SWEET, NUTTY, ALMOND, BALSAM, WOODY |
Taste Description:CREAMY,MUSTY,NUTTY,VANILLA,HONEY |
Cosmetic Information:
Suppliers:
Alfa Biotechnology |
For experimental / research use only. |
p-Hydroxybenzaldehyde 98%
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Beijing Lys Chemicals |
4-Hydroxy benzaldehyde
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BOC Sciences |
For experimental / research use only. |
4-Hydroxybenzaldehyde 98%
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EMD Millipore |
For experimental / research use only. |
4-Hydroxybenzaldehyde
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ExtraSynthese |
For experimental / research use only. |
4-Hydroxybenzaldehyde
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Frinton Laboratories |
For experimental / research use only. |
4-Hydroxybenzaldehyde, Pract.
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Fuzhou Farwell |
P-hydroxy Benzaldehyde
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Hunan Astar Bio-Chemical Technology |
For experimental / research use only. |
4-Hydroxybenzaldehyde
Odor: characteristic Use: It is important fine chemical product and intermediate for organic synthesis, with wide use in pharmaceutical, aromatizer, pesticide, electroplating and liquid crystal industries. In pharmaceutical industry, it can be used to synthesize intermediates of sulfonamides such as broad-spectrum sterilization synergist TMP, ampicillin and semi-synthesized penicillin (oral) as well as intermediate of d-(-)-p-hydroxy phenyl picramate. In aromatizer industry, it is mainly used in raspberry ketone, methyl vanillin, ethyl vanillin, anisic aldehyde and nitrile aromatizer. In pesticide industry, it is mainly used to synthesize new-type insecticide, herbicide, o-bromobenzonitrile and hydroxyl casoron. In electroplating industry, it can be used as a new-type cyanogens-free electroplating brightener |
Inoue Perfumery |
4-HYDROXYBENZALDEHYDE
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Kowa Amerian Corporation |
4-Hydroxybenzaldehyde
Odor: characteristic Use: 4-hydroxybenzaldehyde is a monomer present in high purity. It’s widely used as the starting material for polymers and pharmaceuticals. It’s also a chemical that maintains bactericidal activity when tested against certain bacteria strains |
M&U International |
4-HYDROXY BENZALDEHYDE, Kosher
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Penta International |
p-HYDROXYBENZALDEHYDE
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Prodasynth |
PARA-HYDROXYBENZOIC ALDEHYDE
(> 98%) Odor: SWEET, NUTTY, ALMOND, BALSAM, WOODY Flavor: CREAMY,MUSTY,NUTTY,VANILLA,HONEY |
Santa Cruz Biotechnology |
For experimental / research use only. |
4-Hydroxybenzaldehyde
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Sigma-Aldrich |
4-Hydroxybenzaldehyde, ≥97%, FG
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Certified Food Grade Products |
TCI AMERICA |
For experimental / research use only. |
4-Hydroxybenzaldehyde >98.0%(GC)
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Tianjin Danjun International |
4-Hydroxy benzaldehyde
|
WholeChem |
4-Hydroxy benzaldehyde
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 22 - Do not breath dust. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 3980 mg/kg (Dow Chemical Company, 1992b)
intraperitoneal-mouse LD50 500 mg/kg National Technical Information Service. Vol. AD277-689
oral-rat LD50 2250 mg/kg National Technical Information Service. Vol. OTS0534446
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 4-hydroxybenzaldehyde usage levels up to: | | 0.5000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 55.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 56.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 20 |
Click here to view publication 20 |
| average usual ppm | average maximum ppm |
baked goods: | 5.00000 | 30.00000 |
beverages(nonalcoholic): | 1.00000 | 10.00000 |
beverages(alcoholic): | 3.00000 | 20.00000 |
breakfast cereal: | 5.00000 | 30.00000 |
cheese: | 5.00000 | 30.00000 |
chewing gum: | 10.00000 | 50.00000 |
condiments / relishes: | - | - |
confectionery froastings: | 3.00000 | 20.00000 |
egg products: | 3.00000 | 20.00000 |
fats / oils: | 2.00000 | 20.00000 |
fish products: | - | - |
frozen dairy: | 5.00000 | 20.00000 |
fruit ices: | 2.00000 | 20.00000 |
gelatins / puddings: | 2.00000 | 20.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | 5.00000 | 30.00000 |
imitation dairy: | - | - |
instant coffee / tea: | 5.00000 | 20.00000 |
jams / jellies: | 5.00000 | 20.00000 |
meat products: | - | - |
milk products: | 3.00000 | 20.00000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | 5.00000 | 30.00000 |
snack foods: | - | - |
soft candy: | 5.00000 | 20.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf
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Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf
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Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf
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EPI System: View |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):123-08-0 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :126 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:2 |
4-hydroxybenzaldehyde |
Chemidplus:0000123080 |
RTECS:CU6475000 for cas# 123-08-0 |
References:
Other Information:
Potential Blenders and core components note
For Odor |
No odor group found for these |
(E)- sabinene hydrate FL/FR |
balsamic |
balsamic |
benzoin FL/FR |
siam benzoin absolute FL/FR |
benzoin absolute replacer FL/FR |
sumatra benzoin gum FL/FR |
sumatra benzoin resin FL/FR |
siam benzoin resin FL/FR |
siam benzoin resin oil FR |
benzoin resin replacer FR |
siam benzoin resinoid FL/FR |
sumatra benzoin resinoid FL/FR |
benzoin resinoid replacer FR |
laevo- bornyl acetate FL/FR |
brachyleana hutchinsii wood oil FR |
conifer acetate FR |
fir needle oil canada FL/FR |
fir needle oil terpeneless canada FL/FR |
guaiacyl phenyl acetate FL/FR |
guaiyl butyrate FR |
hemlock western oil (tsuga heterophylla) canada FR |
juniper berry absolute FL/FR |
myrrh absolute FL/FR |
myrrh resinoid FR |
peru balsam replacer FR |
tolu balsam absolute FL/FR |
tolu balsam resin FL/FR |
tolu balsam resinoid FL/FR |
earthy |
nutty pyrazine FL/FR |
floral |
para- cresyl laurate FL/FR |
fruity |
gamma- undecalactone (aldehyde C-14 (so-called)) FL/FR |
vanilla carboxylate FL/FR |
green |
galbanum oleoresin FL/FR |
galbanum resinoid FL/FR |
valerian rhizome oil CO2 extract china FL/FR |
herbal |
canarium luzonicum gum FL/FR |
rosemary absolute FL/FR |
rosemary oil morocco FL/FR |
rosemary oil spain FL/FR |
valerian rhizome oil FL/FR |
valerian rhizome oil china FL/FR |
medicinal |
quinoline CS |
musty |
2- acetyl pyrrole FL/FR |
3- acetyl-2,5-dimethyl furan FL/FR |
menthofuran FL/FR |
nutty |
2- acetyl-3-ethyl pyrazine FL/FR |
2- ethyl pyrazine FL/FR |
filbert pyrazine FL/FR |
2- methyl-3-(methyl thio) pyrazine FL/FR |
nutty cyclohexenone FL/FR |
nutty quinoxaline FL/FR |
2,3,5,6- tetramethyl pyrazine FL/FR |
2,3,5- trimethyl pyrazine FL/FR |
vinyl sulfurol FL/FR |
powdery |
para- anisyl acetate FL/FR |
terpenic |
elemi resinoid FL/FR |
woody |
copaiba balsam FL/FR |
alpha- guaiene FL/FR |
gurjun balsam oil FR |
alpha- gurjunene FR |
patchouli oil FL/FR |
sandalwood oil FL/FR |
sandalwood oil west australia (santalum spicatum) FR |
santalyl butyrate FL/FR |
vetiverol FL/FR |
For Flavor |
No flavor group found for these |
benzoin FL/FR |
fir needle oil canada FL/FR |
alpha- guaiene FL/FR |
2,4- heptadien-1-ol FL |
(E,E)-2,4- heptadien-1-ol FL |
2- methyl-3-(methyl thio) pyrazine FL/FR |
(E)- sabinene hydrate FL/FR |
santalyl butyrate FL/FR |
balsamic |
balsamic |
benzoin absolute replacer FL/FR |
sumatra benzoin gum FL/FR |
sumatra benzoin resin FL/FR |
siam benzoin resin FL/FR |
sumatra benzoin resinoid FL/FR |
siam benzoin resinoid FL/FR |
laevo- bornyl acetate FL/FR |
fir needle oil terpeneless canada FL/FR |
juniper berry absolute FL/FR |
myrrh absolute FL/FR |
peru balsam FL |
tolu balsam absolute FL/FR |
tolu balsam resin FL/FR |
tolu balsam resinoid FL/FR |
buttery |
butter nut vanilla flavor FL |
butter vanilla nut flavor FL |
creamy |
gamma- undecalactone (aldehyde C-14 (so-called)) FL/FR |
fruity |
para- anisyl acetate FL/FR |
2,4- hexadien-1-ol FL |
(E,E)- methyl sorbate FL |
valerian rhizome oil FL/FR |
valerian rhizome oil china FL/FR |
valerian rhizome oil CO2 extract china FL/FR |
vanilla carboxylate FL/FR |
green |
canarium luzonicum gum FL/FR |
elemi resinoid FL/FR |
galbanum oleoresin FL/FR |
galbanum resinoid FL/FR |
herbal |
rosemary absolute FL/FR |
rosemary oil morocco FL/FR |
rosemary oil spain FL/FR |
musty |
menthofuran FL/FR |
2,3,5- trimethyl pyrazine FL/FR |
nutty |
2- acetyl pyrrole FL/FR |
3- acetyl-2,5-dimethyl furan FL/FR |
2- acetyl-3-ethyl pyrazine FL/FR |
2- ethyl pyrazine FL/FR |
filbert pyrazine FL/FR |
nutty cyclohexenone FL/FR |
nutty pyrazine FL/FR |
nutty quinoxaline FL/FR |
peanut oxazole FL |
2,3,5,6- tetramethyl pyrazine FL/FR |
vinyl sulfurol FL/FR |
phenolic |
guaiacyl phenyl acetate FL/FR |
spicy |
siam benzoin absolute FL/FR |
vanilla |
vanilla nut creme flavor FL |
waxy |
para- cresyl laurate FL/FR |
woody |
copaiba balsam FL/FR |
patchouli oil FL/FR |
sandalwood oil FL/FR |
vetiverol FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
para-oxy | benzaldehyde | | benzaldehyde, 4-hydroxy- | | benzaldehyde, p-hydroxy- | 4- | formyl phenol | p- | formyl phenol | para- | formyl phenol | 4- | formylphenol | p- | formylphenol | para- | formylphenol | 4- | hydroxy benzaldehyde | 4- | hydroxy-benzaldehyde | p- | hydroxybenzaldehyde | para- | hydroxybenzaldehyde | 4- | hydroxybenzaldehyde, pract. |
Articles:
PubMed:Phytochemical Screening, Anticancer and Antioxidant Activities of Origanum vulgare L. subsp. viride (Boiss.) Hayek: A Plant of Traditional Usage. |
PubMed:Biocatalytic behaviour of immobilized Rhizopus oryzae lipase in the 1,3-selective ethanolysis of sunflower oil to obtain a biofuel similar to biodiesel. |
PubMed:Identification and analysis of gastrodin and its five metabolites using ultra fast liquid chromatography electrospray ionization tandem mass spectrometry to investigate influence of multiple-dose and food. |
PubMed:Inhibitory activity of carbonyl compounds on alcoholic fermentation by Saccharomyces cerevisiae. |
PubMed:Breaking down lignin to high-value chemicals: the conversion of lignocellulose to vanillin in a gene deletion mutant of Rhodococcus jostii RHA1. |
PubMed:Antioxidant activity of sugarcane molasses against 2,2'-azobis(2-amidinopropane) dihydrochloride-induced peroxyl radicals. |
PubMed:Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. |
PubMed:Syzygium aqueum leaf extract and its bioactive compounds enhances pre-adipocyte differentiation and 2-NBDG uptake in 3T3-L1 cells. |
PubMed:Shikimate pathway modulates the elicitor-stimulated accumulation of fragrant 2-hydroxy-4-methoxybenzaldehyde in Hemidesmus indicus roots. |
PubMed:Rapid discrimination and characterization of vanilla bean extracts by attenuated total reflection infrared spectroscopy and selected ion flow tube mass spectrometry. |
PubMed:Synthesis and antityrosinase mechanism of benzaldehyde thiosemicarbazones: novel tyrosinase inhibitors. |
PubMed:Oxidation of synthetic phenolic antioxidants during water chlorination. |
PubMed:Ethnobotanical survey, chemical composition, and antioxidant capacity of methanolic extract of the root bark of Annona cuneata Oliv. |
PubMed:Bound aroma compounds of Gual and Listán blanco grape varieties and their influence in the elaborated wines. |
PubMed:Antimutagenic constituents of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity. |
PubMed:Comparison of gas chromotography, spectrophotometry and near infrared spectroscopy to quantify prussic acid potential in forages. |
PubMed:Mechanism of the organocatalyzed decarboxylative Knoevenagel-Doebner reaction. A theoretical study. |
PubMed:Substrate profiling and aldehyde dismutase activity of the Kvβ2 subunit of the mammalian Kv1 potassium channel. |
PubMed:Determination of synthetic phenolic antioxidants and their metabolites in water samples by downscaled solid-phase extraction, silylation and gas chromatography-mass spectrometry. |
PubMed:Gastrodia elata Blume water extracts improve insulin resistance by decreasing body fat in diet-induced obese rats: vanillin and 4-hydroxybenzaldehyde are the bioactive candidates. |
PubMed:Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01. |
PubMed:Antioxidant activity and chemical composition of Torreya grandis cv. Merrillii seed. |
PubMed:Biosynthesis of vanillin via ferulic acid in Vanilla planifolia. |
PubMed:Fast single run of vanilla fingerprint markers on microfluidic-electrochemistry chip for confirmation of common frauds. |
PubMed:Metabolic changes in different developmental stages of Vanilla planifolia pods. |
PubMed:Bioactive phenols in algae: the application of pressurized-liquid and solid-phase extraction techniques. |
PubMed:Miscanthus x giganteus extractives: a source of valuable phenolic compounds and sterols. |
PubMed:Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota 2: confirming biosynthetic steps through feeding of inhibitors and precursors. |
PubMed:Adsorbed resin phase spectrophotometric determination of vanillin or/and its derivatives. |
PubMed:Chemical constituents of Antrodia camphorata submerged whole broth. |
PubMed:Production of phytotoxins by Phoma exigua var. exigua, a potential mycoherbicide against perennial thistles. |
PubMed:Accumulation of phenylpropanoid derivatives in chitosan-induced cell suspension culture of Cocos nucifera. |
PubMed:Polymerized coumaric acid as a model substrate for terrestrial-derived dissolved organic carbon utilized by aquatic microorganisms. |
PubMed:Accumulation of cell wall-bound phenolic metabolites and their upliftment in hairy root cultures of tomato (Lycopersicon esculentum Mill.). |
PubMed:Oxidative transformation of natural and synthetic phenolic mixtures by Trametes versicolor laccase. |
PubMed:Antioxidant activity of sugar molasses, including protective effect against DNA oxidative damage. |
PubMed:Effect of phenolic aldehydes and flavonoids on growth and inactivation of Oenococcus oeni and Lactobacillus hilgardii. |
PubMed:Studies on the antioxidant activities of natural vanilla extract and its constituent compounds through in vitro models. |
PubMed:Evidence for p-hydroxybenzoate formation involving enzymatic phenylpropanoid side-chain cleavage in hairy roots of Daucus carota. |
PubMed:Microbial production of 4-hydroxybenzylidene acetone, the direct precursor of raspberry ketone. |
PubMed:Chemical constituents of cape aloe and their synergistic growth-inhibiting effect on Ehrlich ascites tumor cells. |
PubMed:Specific pretreatments reduce curing period of vanilla (Vanilla planifolia) beans. |
PubMed:[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium]. |
PubMed:Metabolic diversion of the phenylpropanoid pathway causes cell wall and morphological changes in transgenic tobacco stems. |
PubMed:[Production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension cultures of Datura tatula L]. |
PubMed:Optimization of extraction of phenolic compounds from flax shives by pressurized low-polarity water. |
PubMed:Biotransformation of p-coumaric acid by Paecilomyces variotii. |
PubMed:Transformation of Eutypa dieback and esca disease pathogen toxins by antagonistic fungal strains reveals a second detoxification pathway not present in Vitis vinifera. |
PubMed:Profiling C6-C3 and C6-C1 phenolic metabolites in Cocos nucifera. |
PubMed:Structure-function analysis of the vanillin molecule and its antifungal properties. |
PubMed:Chemical investigation and authenticity of Indian vanilla beans. |
PubMed:Metabolism of gallic acid and catechin by Lactobacillus hilgardii from wine. |
PubMed:Radical-scavenging activity of butylated hydroxytoluene (BHT) and its metabolites. |
PubMed:An efficient isocratic separation of hydroxycinnamates and their corresponding benzoates from microbial and plant sources by HPLC. |
PubMed:Vanillins--a novel family of DNA-PK inhibitors. |
PubMed:Effect of far-infrared radiation on the antioxidant activity of rice hulls. |
PubMed:Vanillin. |
PubMed:Quantitative changes in phenolic content during physiological development of the olive (Olea europaea) cultivar Hardy's Mammoth. |
PubMed:Analysis of the antioxidant butylated hydroxytoluene (BHT) in water by means of solid phase extraction combined with GC/MS. |
PubMed:4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L. |
PubMed:Isolation and characterization of the antioxidant component 3,4-dihydroxyphenylethyl 4-formyl-3-formylmethyl-4-hexenoate from olive (Olea europaea) leaves. |
PubMed:Properties of diphenolase from Vanilla planifolia (Andr.) shoot primordia cultured in vitro. |
PubMed:Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function. |
PubMed:Aroma-active components of nonfat dry milk. |
PubMed:Reactions of p-coumaric acid with nitrite: product isolation and mechanism studies. |
PubMed:Ozonation Products of Organosolvolytic Extracts from Vegetal Materials. |
PubMed:Natural Abundance (2)H Nuclear Magnetic Resonance Study of the Origin of Raspberry Ketone. |
PubMed:Brominated anisoles and cresols in the red alga Polysiphonia sphaerocarpa. |
PubMed:Effect of selected aldehydes on the growth and fermentation of ethanologenic Escherichia coli. |
PubMed:Oxidative DNA damage and apoptosis induced by metabolites of butylated hydroxytoluene. |
PubMed:Determination of coumarin as an adulterant in vanilla flavoring products by high-performance liquid chromatography. |
PubMed:Reactions of antioxidants in foods. |
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Occurs naturally combined in many glycosides. Constit. of vanillin. Isol. in free state from opium poppy (Papaver somniferum)
4-Hydroxybenzaldehyde reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. The reaction is catalyzed by 4-hydroxybenzaldehyde dehydrogenase.; ; 4-Hydroxybenzaldehyde is found in the benzoate degradation via hydroxylation, bisphenol A degradation, toluene and xylene degradation, and biosynthesis of phenylpropanoids pathways.
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