Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | yellow clear oily liquid (est) |
Assay: | 97.00 to 100.00
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.94100 to 0.94900 @ 20.00 °C.
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Pounds per Gallon - (est).: | 7.839 to 7.906
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Refractive Index: | 1.39900 to 1.41200 @ 20.00 °C.
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Melting Point: | -10.00 °C. @ 760.00 mm Hg
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Boiling Point: | 123.00 to 125.00 °C. @ 760.00 mm Hg
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Boiling Point: | 49.00 °C. @ 13.00 mm Hg
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Vapor Pressure: | 9.907000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 3.9 ( Air = 1 ) |
Flash Point: | 88.00 °F. TCC ( 31.11 °C. )
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logP (o/w): | -0.321 (est) |
Soluble in: |
| alcohol | | water, slightly | | water, 2.113e+005 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Type: buttery |
buttery almond toasted almond nutty caramellic |
Odor Description:at 1.00 % in dipropylene glycol. buttery toasted almond nutty caramellic |
Flavor Type: buttery |
caramellic nutty buttery |
Taste Description: caramel nutty buttery |
Odor and/or flavor descriptions from others (if found). |
Ernesto Ventós |
3,4-HEXANEDIONE |
Odor Description:BUTTER,TOASTED,ALMOND,NUTTY,CARAMEL |
Taste Description:butter |
Cosmetic Information:
Suppliers:
Augustus Oils |
3,4 Hexanedione
|
Services |
Beijing Lys Chemicals |
3,4-Hexanedione
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BOC Sciences |
For experimental / research use only. |
3,4-Hexanedione
|
Charkit Chemical |
HEXANEDIONE, 3,4- H0450 FEMA 3168
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DeLong Chemicals America |
3,4-Hexanedione
|
Ernesto Ventós |
3,4-HEXANEDIONE
Odor: BUTTER,TOASTED,ALMOND,NUTTY,CARAMEL |
FCI SAS |
3,4-HEXANEDIONE
Odor: Butyric sweet |
Frutarom |
3,4-HEXANEDIONE
KOSHER Flavor: Buttery, Almond, Toasted, Nutty, Caramellic |
CBD Offering |
IFF |
3,4-HEXANEDIONE
KOSHER Flavor: Buttery, Almond, Toasted, Nutty, Caramellic |
Jinan Enlighten Chemical Technology(Wutong Aroma ) |
3,4-Hexanedione, Kosherk
|
Kingchem Laboratories |
3, 4 HEXANEDIONE, 96.00%+
|
Kingchem Laboratories |
3, 4 HEXANEDIONE
Odor: Butyric sweet |
M&U International |
3,4-HEXANEDIONE, Kosher
|
O'Laughlin Industries |
3,4-HEXANEDIONE
|
Penta International |
3,4-HEXANEDIONE
|
Santa Cruz Biotechnology |
For experimental / research use only. |
3,4-Hexanedione ≥94%
|
Sigma-Aldrich |
3,4-Hexanedione, ≥90%
Odor: caramel; creamy; coffee |
Certified Food Grade Products |
Sunaux International |
3,4-Hexanedione
|
Synerzine |
3,4-Hexanedione
|
Taytonn ASCC |
3,4-Hexanedione
Odor: Buttery, Caramellic/ Caramel, Pungent |
TCI AMERICA |
For experimental / research use only. |
3,4-Hexanedione >96.0%(GC)
|
Tengzhou Jitian Aroma Chemiclal |
3,4-Hexanedione
|
Tianjin Danjun International |
3,4-Hexanedione
|
United International |
3,4-Hexanedione
|
WholeChem |
3,4-Hexanedione
|
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 10 - Flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 3,4-hexane dione usage levels up to: | | 1.0000 % in the fragrance concentrate.
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|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 21.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 4 |
Click here to view publication 4 |
| average usual ppm | average maximum ppm |
baked goods: | - | - |
beverages(nonalcoholic): | - | 10.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 10.00000 |
fruit ices: | - | 10.00000 |
gelatins / puddings: | - | 10.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 10.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 11 (FGE.11): Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf
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Flavouring Group Evaluation 11, Revision 1 (FGE.11Rev1) - Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf
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Safety and efficacy of secondary aliphatic saturated or unsaturated alcohols, ketones, ketals and esters with a second secondary or tertiary oxygenated functional group belonging to chemical group 10 when used as flavourings for all animal species View page or View pdf
|
EPI System: View |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):4437-51-8 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :62539 |
National Institute of Allergy and Infectious Diseases:Data |
WISER:UN 1224 |
WGK Germany:1 |
hexane-3,4-dione |
Chemidplus:0004437518 |
References:
Other Information:
Potential Blenders and core components note
For Odor |
No odor group found for these |
butter starter distillates FL/FR |
acidic |
acidic |
iso butyric acid FL/FR |
2- methyl butyric acid FL/FR |
aldehydic |
acetyl nonyryl FL/FR |
balsamic |
cinnamyl benzoate FL/FR |
bready |
coffee furanone FL/FR |
furfural FL/FR |
buttery |
acetoin FL/FR |
acetoin dimer FL/FR |
acetoin propylene glycol acetal FL/FR |
acetyl butyryl FL/FR |
acetyl isobutyryl FL/FR |
acetyl propionyl FL/FR |
butter oil CO2 extract FL/FR |
butyl butyryl lactate FL/FR |
iso butyl lactate FL/FR |
butyl octanoate FL/FR |
2,3- heptane dione FL/FR |
caramellic |
cyclotene FL/FR |
alpha,alpha- dimethyl anisyl acetone FL/FR |
ethyl 2-hydroxy-2-methyl butyrate FL/FR |
cheesy |
butyric acid FL/FR |
2- methyl valeric acid FL/FR |
coconut |
coconut naphthalenone FL/FR |
delta- decalactone FL/FR |
gamma- heptalactone FL/FR |
gamma- nonalactone (aldehyde C-18 (so-called)) FL/FR |
delta- undecalactone FL/FR |
corn chip |
popcorn pyrimidine FL/FR |
coumarinic |
epsilon- decalactone FL/FR |
tonka bean resinoid FR |
creamy |
waxy lactone FL/FR |
fatty |
butter esters FL/FR |
butyl undecylenate FL/FR |
fermented |
butyl laevo-lactate FL/FR |
floral |
benzyl lactate FL/FR |
jasmin pyranone FL/FR |
linalyl butyrate FL/FR |
fruity |
acetoin acetate FL/FR |
gamma- decalactone FL/FR |
ethyl lactate FL/FR |
2- nonanone FL/FR |
prenyl isobutyrate FL/FR |
sorbyl butyrate FL/FR |
tetrahydrofurfuryl acetate FL/FR |
green |
(Z)-4- heptenal FL/FR |
(Z)-3- hexen-1-yl butyrate FL/FR |
(E,Z)-2,6- nonadienal FL/FR |
mushroom |
1- octen-3-yl butyrate FL/FR |
musty |
3- acetyl-2,5-dimethyl furan FL/FR |
nutty |
2- acetyl-3-methyl pyrazine FL/FR |
3,5- cocoa pyrazine FL/FR |
2- ethyl pyrazine FL/FR |
5- methyl quinoxaline FL/FR |
2- methyl-3-(methyl thio) pyrazine FL/FR |
nutty cyclohexenone FL/FR |
oily |
butter acids FL/FR |
soapy |
ethyl undecanoate FL/FR |
tonka |
tonka bean absolute FR |
whiskey lactone FL/FR |
tropical |
delta- dodecalactone FL/FR |
glyceryl 5-hydroxydecanoate FL/FR |
glyceryl 5-hydroxydodecanoate FL/FR |
waxy |
2- methyl heptanoic acid FL/FR |
delta- tetradecalactone FL/FR |
woody |
4- hydroxybenzaldehyde FL/FR |
For Flavor |
No flavor group found for these |
benzyl lactate FL/FR |
butter nut rum flavor FL |
butyl octanoate FL/FR |
cinnamyl benzoate FL/FR |
coconut naphthalenone FL/FR |
6- decenoic acid FL |
alpha,alpha- dimethyl anisyl acetone FL/FR |
ethyl 2-hydroxy-2-methyl butyrate FL/FR |
(E,E)-2,4- heptadien-1-ol FL |
2,4- heptadien-1-ol FL |
3-( methyl thio) hexanal FL |
2- methyl-3-(methyl thio) pyrazine FL/FR |
prenyl isobutyrate FL/FR |
sodium 4-methyl-2-oxovalerate FL |
acidic |
acidic |
iso butyric acid FL/FR |
aldehydic |
acetyl nonyryl FL/FR |
alliaceous |
3- tetrahydrothiophenone FL |
bitter |
glyceryl tributyrate FL |
brown |
furfural FL/FR |
tetrahydrofurfuryl acetate FL/FR |
burnt |
2- methyl quinoxaline FL |
buttery |
acetoin propylene glycol acetal FL/FR |
bovolide FL |
butter cream frosting flavor FL |
butter enhancers FL |
creamy butter flavor FL |
butter flavor FL |
sweet butter flavor FL |
butter maple flavor FL |
butter nut vanilla flavor FL |
butter oil CO2 extract FL/FR |
butter pecan flavor FL |
butter praline flavor FL |
butter starter distillates FL/FR |
butter toffee flavor FL |
butter vanilla nut flavor FL |
iso butyl lactate FL/FR |
butyl laevo-lactate FL/FR |
butyroin FL |
diacetyl FL |
ghee flavor FL |
2,3- heptane dione FL/FR |
2- methyl valeric acid FL/FR |
(E)-2- pentenoic acid FL |
caramellic |
butter rum toffee flavor FL |
caramel nut cream flavor FL |
caramel nut fudge flavor FL |
cyclotene FL/FR |
maple nut flavor FL |
3- methyl butyl 2-furyl butyrate FL |
cheesy |
2- nonanone FL/FR |
chocolate |
chocolate butter cream flavor FL |
chocolate caramel nut flavor FL |
citrus |
butter lemon orange flavor FL |
cocoa |
2- methyl furan FL |
coconut |
delta- decalactone FL/FR |
gamma- nonalactone (aldehyde C-18 (so-called)) FL/FR |
corn chip |
popcorn pyrimidine FL/FR |
creamy |
acetoin FL/FR |
acetoin butyrate FL |
acetyl butyryl FL/FR |
acetyl ethyl carbinol FL |
acetyl isobutyryl FL/FR |
butter esters FL/FR |
butter fat enzyme modified with added butyric acid FL |
butyl butyryl lactate FL/FR |
5,5- dibutyl dihydrofuran-2(3H)-one FL |
divanillin FL |
delta- dodecalactone FL/FR |
glyceryl 5-hydroxydecanoate FL/FR |
glyceryl 5-hydroxydodecanoate FL/FR |
4- hydroxybenzaldehyde FL/FR |
jasmin pyranone FL/FR |
delta- undecalactone FL/FR |
waxy lactone FL/FR |
dairy |
acetoin dimer FL/FR |
fatty |
butter acids FL/FR |
diacetyl trimer FL |
(E,E)-2,4- undecadienal FL |
floral |
linalyl butyrate FL/FR |
fruity |
acetoin acetate FL/FR |
acetyl isovaleryl FL |
gamma- decalactone FL/FR |
ethyl lactate FL/FR |
2,4- hexadien-1-ol FL |
2- methyl butyric acid FL/FR |
sorbyl butyrate FL/FR |
green |
(Z)-4- heptenal FL/FR |
(Z)-3- hexen-1-yl butyrate FL/FR |
(E,Z)-2,6- nonadienal FL/FR |
lactonic |
gamma- heptalactone FL/FR |
metallic |
2,5- dihydroxy-1,4-dithiane FL |
mushroom |
1- octen-3-yl butyrate FL/FR |
nutty |
3- acetyl-2,5-dimethyl furan FL/FR |
2- acetyl-3-methyl pyrazine FL/FR |
butter pecan cake flavor FL |
3,5- cocoa pyrazine FL/FR |
coffee furanone FL/FR |
2,5- diethyl-3-methyl pyrazine FL |
2- ethyl pyrazine FL/FR |
5- methyl quinoxaline FL/FR |
nutty cyclohexenone FL/FR |
peanut brittle flavor FL |
peanut oxazole FL |
sour |
butyric acid FL/FR |
spicy |
spiced butter rum flavor FL |
cinnamon butter pecan flavor FL |
cinnamon nut butter rum flavor FL |
sweet |
honey distillates FL |
vanilla butter nut flavor FL |
toasted |
acetyl propionyl FL/FR |
waxy |
butyl undecylenate FL/FR |
epsilon- decalactone FL/FR |
ethyl undecanoate FL/FR |
2- methyl heptanoic acid FL/FR |
delta- tetradecalactone FL/FR |
winey |
5- ethyl-2-methyl pyridine FL |
woody |
whiskey lactone FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| bipropionyl | | diethyl diketone | 3,4- | dioxohexane | | dipropionyl | | hexan-3,4-dione | 3,4- | hexandione | | hexane-3,4-dione | 3, 4 | hexanedione | 3,4- | hexanedione |
Articles:
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