TGSC Information System

EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

4-methyl-2,6-dimethoxyphenol
2,6-dimethoxy-p-cresol

Supplier Sponsors

BOC Sciences

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
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US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
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Europe	44-203-286-1088
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Product(s):
6638-05-7 4-Methyl-2,6-dimethoxyphenol 95%

Penta International Corporation

Chemistry innovation
At Penta, our products and services help businesses do business better.
For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
US Email:	Technical Services
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US Voice: (973) 740-2300
US Fax: (973) 740-1839
GSC103751103632 GSC103751103632
Product(s):
13-40250 4-METHYL-2,6-DIMETHOXYPHENOL

Sigma-Aldrich

Complete Supply Chain
The perfect blend of products and services that bring your creativity to life.
Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
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Flavors and Fragrances Analysis
FandF Newsletter Subscription
Flavors and Fragrances Learning Center
Certified Food Grade Products
GSC103751103632 GSC103751103632
Product(s):
W370401 4-Methyl-2,6-dimethoxyphenol, ≥97%
SDS

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.
Synerzine is a leading supplier of flavor and fragrance ingredients.
Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
US Email:	Customer Service
US Email:	Sales
US Voice: (404) 524-6744
US Fax: (404) 577-1651
Inquiry
Products List:	View
GSC103751103632 GSC103751103632
Product(s):
W1424 4-Methyl-2,6-dimethoxyphenol

TCI AMERICA

Moving Your Chemistry Forward
We continuously strive to advance our technology.
With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
US Email:	Sales
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GSC103751103632 GSC103751103632
Product(s):
D2591 4-Methyl-2,6-dimethoxyphenol >97.0%(GC)
SDS

CAS Number:	6638-05-7	3D/inchi
ECHA EINECS - REACH Pre-Reg:	229-641-6
FDA UNII:	FJJ5MYE75W
Nikkaji Web:	J27.322H
MDL:	MFCD00017289
XlogP3-AA:	1.90 (est)
Molecular Weight:	168.19224000
Formula:	C9 H12 O3
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:flavor and fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Flavoring:	722 4-methyl-2,6-dimethoxyphenol
DG SANTE Food Flavourings:	04.053 4-methyl-2,6-dimethoxyphenol
FEMA Number:	3704 4-methyl-2,6-dimethoxyphenol
FDA:	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):	6638-05-7 ; 4-METHYL-2,6-DIMETHOXYPHENOL

Physical Properties:

Appearance:	yellow to orange solid (est)
Assay:	97.00 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	37.00 to 42.00 °C. @ 760.00 mm Hg
Boiling Point:	145.00 to 146.00 °C. @ 14.00 mm Hg
Vapor Pressure:	0.005000 mmHg @ 25.00 °C. (est)
Flash Point:	> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w):	1.859 (est)
Soluble in:
	alcohol
	water, 2173 mg/L @ 25 °C (est)
Insoluble in:
	water

Organoleptic Properties:

Odor Type: phenolic

phenolic smoky medicinal woody spicy clove rooty caramellic

Odor Description:at 10.00 % in dipropylene glycol. phenolic smoke medicinal woody spice eugenol root caramel

phenolic smoky medicinal woody spicy clove rooty caramellic

Odor Description:Phenolic, smokey, medicinal, woody, spicy, eugenol-like and rooty with a caramellic nuance
Mosciano, Gerard P&F 19, No. 3, 51, (1994)

Flavor Type: phenolic

phenolic medicinal musty guaiacol smoky

Taste Description: at 10.00 ppm. Phenolic, medicinal, musty and guaiacol with a smoky nuance
Mosciano, Gerard P&F 19, No. 3, 51, (1994)

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

4-Methyl-2,6-dimethoxyphenol 95%

Coompo

For experimental / research use only.

Methylsyringol from Plants ≥98%

Jalor-Chem

For experimental / research use only.

2,6-Dimethoxy-4-methylphenol

Parchem

4-methyl-2,6-dimethoxyphenol

Penta International

4-METHYL-2,6-DIMETHOXYPHENOL

Santa Cruz Biotechnology

For experimental / research use only.

4-Methyl-2,6-dimethoxyphenol

Sigma-Aldrich

4-Methyl-2,6-dimethoxyphenol, ≥97%

sds

Certified Food Grade Products

Synerzine

4-Methyl-2,6-dimethoxyphenol

TCI AMERICA

For experimental / research use only.

4-Methyl-2,6-dimethoxyphenol >97.0%(GC)

sds

Safety Information:

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 [sex: M,F] 1700 mg/kg (Piccirillo & Hartman, 1982)
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 4-methyl-2,6-dimethoxyphenol usage levels up to:
	0.1000 % in the fragrance concentrate.

Maximised Survey-derived Daily Intakes (MSDI-EU):		0.054 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA):		0.04 (μg/capita/day)
Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 13
Click here to view publication 13
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	1.00000
chewing gum:		-	-
condiments / relishes:		-	5.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	1.00000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	1.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	0.50000
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	5.00000
snack foods:		-	1.00000
soft candy:		-	-
soups:		-	0.50000
sugar substitutes:		-	-
sweet sauces:		-	-

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 22 (FGE.22): Ring-substituted phenolic substances from chemical groups 21 and 25 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 58 (FGE.58) Consideration of phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated by EFSA in FGE.22 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 22, Revision 1 (FGE.22Rev1): Ring-substituted phenolic substances from chemical groups 21 and 25
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87.
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :240925

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

2,6-dimethoxy-4-methylphenol

Chemidplus:0006638057

References:

	2,6-dimethoxy-4-methylphenol
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	6638-05-7
Pubchem (cid):	240925
Pubchem (sid):	135264215

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB29680
FooDB:	FDB000865
Export Tariff Code:	2909.50.5000
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

For Odor

aldehydic

dodecanal (aldehyde C-12 lauric)
FL/FR

10-

undecenal (aldehyde C-11 undecylenic)
FL/FR

amber

amber carane
FR

ambroxan
FL/FR

angelica root oil
FL/FR

cistus ladaniferus resinoid
FL/FR

animal

iso

butyl quinoline
FR

iso

butyl quinoline
FR

costus valerolactone
FR

para-

cresyl caprylate
FL/FR

musk indenofuran
FR

anise

anise seed oil colombia
FL/FR

estragon absolute
FR

anisic

ortho-

acetanisole
FL/FR

para-

anisaldehyde
FL/FR

dihydroanethol
FL/FR

balsamic

amyris wood oil
FL/FR

sumatra

benzoin absolute
FL/FR

siam

benzoin resinoid
FL/FR

benzyl salicylate
FL/FR

iso

bornyl acetate
FL/FR

laevo-

bornyl acetate
FL/FR

iso

butyl cinnamate
FL/FR

clover nitrile
FR

croton glabellus bark extract
FL/FR

ethyl cinnamate
FL/FR

fir balsam absolute
FR

frankincense absolute
FL/FR

guaiyl acetate
FL/FR

khella oil
FR

methyl cinnamate
FL/FR

myrrh resinoid
FR

opoponax absolute (balsamodendron kafal)
FL/FR

phenyl propyl alcohol
FL/FR

valeriana wallichii root oil
FR

burnt

amber oil
FR

camphoreous

dextro-

camphor
FL/FR

caramellic

cyclotene
FL/FR

immortelle absolute
FL/FR

maltol
FL/FR

chocolate

vanillyl ethyl ether
FL/FR

coconut

gamma-

heptalactone
FL/FR

gamma-

nonalactone (aldehyde C-18 (so-called))
FL/FR

gamma-

octalactone
FL/FR

coffee

furfuryl mercaptan
FL/FR

coumarinic

phthalide
FL/FR

creamy

para-

vanillyl alcohol
FL/FR

earthy

octanol
FL/FR

floral

iso

amyl salicylate
FL/FR

benzyl alcohol
FL/FR

iso

butyl salicylate
FL/FR

cassis specialty
FR

para-

cresyl acetate
FL/FR

dimethyl anthranilate
FL/FR

heliotropin
FL/FR

heliotropyl acetone
FL/FR

alpha-

hexyl cinnamaldehyde
FL/FR

mimosa absolute
FL/FR

mimosa absolute france
FL/FR

mimosa absolute india
FL/FR

orris pyridine 25% IPM
FR

phenethyl alcohol
FL/FR

phenethyl phenyl acetate
FL/FR

rose concrete (rosa centifolia)
FR

fruity

ethyl 3-hydroxyhexanoate
FL/FR

meta-

tolualdehyde
FL/FR

para-

tolualdehyde
FL/FR

green

para-

dimethyl hydroquinone
FL/FR

3,7-

dimethyl-6-octenoic acid
FL/FR

diphenyl oxide
FL/FR

octanal diethyl acetal
FL/FR

seaweed absolute (fucus vesiculosus et serratus)
FL/FR

hay

hay absolute
FR

herbal

acorus calamus rhizome oil
FR

anthemis nobilis flower oil roman
FL/FR

sweet

basil absolute
FL/FR

calamintha clinopodium oil
FR

canarium luzonicum oil
FL/FR

clary sage oil france
FL/FR

dill seed oil
FL/FR

dill seed oil CO2 extract
FL/FR

linalyl acetate
FL/FR

nonisyl acetate
FR

curled

parsley seed oil
FL/FR

petroselinum crispum seed oil CO2 extract
FL/FR

safranal
FL/FR

common

tansy flower oil
FR

common

tansy flower oil dutch
FR

theaspirane
FL/FR

thymol
FL/FR

yerba mate absolute
FL/FR

honey

methyl phenyl acetate
FL/FR

phenyl pyruvic acid
FL/FR

leathery

castoreum absolute
FL/FR

medicinal

2,6-

xylenol
FL/FR

minty

piperitenone
FL/FR

iso

pulegol
FL/FR

(-)-iso

pulegol
FL/FR

mossy

oakmoss absolute
FL/FR

sea resorcylate
FR

veramoss (IFF)
FR

musk

musk indanone
FR

nutty

nutty cyclohexenone
FL/FR

orris

eugenyl formate
FL/FR

para-iso

propyl acetophenone
FL/FR

peppery

asarum europaeum oil
FR

phenolic

ortho-

cresyl isobutyrate
FL/FR

2,3-

dimethyl benzofuran
FL/FR

para-alpha-

dimethyl styrene
FL/FR

ortho-

guaiacol
FL/FR

2'-

hydroxyacetophenone
FL/FR

methyl benzoate
FL/FR

piper betle leaf oil
FR

propyl phenol
FL/FR

2-iso

propyl phenol
FL/FR

vinyl phenol
FL/FR

2,3-

xylenol
FL/FR

2,5-

xylenol
FL/FR

powdery

para-

anisyl acetate
FL/FR

saffron

saffron stigmates absolute
FR

smoky

birch tar oil
FL/FR

cade oil
FR

2,6-

dimethoxyphenol
FL/FR

alpha-

ethoxy-ortho-cresol
FL/FR

ethyl phenol
FL/FR

propyl paraben
CS

pyroligneous acids
FL/FR

pyroligneous acids hickory
FL/FR

spicy

allspice berry absolute
FL/FR

allspice oil
FL/FR

anona squamosa leaf oil
FR

artemisia dracunculus herb oil
FL/FR

atractylis root oil
FR

ayou wood oil
FR

benzyl isoeugenol
FL/FR

carvacrol
FL/FR

caryophyllene
FL/FR

beta-

caryophyllene
FL/FR

alpha-

caryophyllene alcohol
FL/FR

cascarilla oil replacer
FL/FR

cassia bark oil china
FL/FR

cassia leaf oil
FL/FR

cinnamon bark oil
FL/FR

cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR

cinnamon bark oil ceylon
FL/FR

cinnamon leaf oil ceylon
FL/FR

cinnamon oleoresin ceylon
FL/FR

clove bud absolute
FL/FR

clove bud oil
FL/FR

clove bud oil CO2 extract
FL/FR

croton eluteria bark oil
FL/FR

ethyl guaiacol
FL/FR

eugenol
FL/FR

iso

eugenyl acetate
FL/FR

galangal root oil
FL/FR

ginger oleoresin africa
FL/FR

ginger root oil brazil
FL/FR

ginger root oil china
FL/FR

grains of paradise oil
FL/FR

green oxane
FR

mace absolute
FL/FR

mace oil
FL/FR

machilus kusanoi leaf oil
FR

machilus kusanoi wood oil
FR

maja fragrance
FR

ortho-

methoxycinnamaldehyde
FL/FR

alpha-

methyl cinnamaldehyde
FL/FR

methyl guaiacol
FL/FR

methyl isoeugenol
FL/FR

myristica fragrans fruit extract
FL/FR

myristica fragrans seed tincture
FL/FR

nutmeg oil
FL/FR

black

pepper absolute
FL/FR

pepper hexanone
FR

black

pepper oil CO2 extract
FL/FR

pepper tree berry absolute
FL/FR

pepper tree berry oil
FL/FR

pepper tree berry oil CO2 extract
FL/FR

piper longum fruit oil
FL/FR

piper longum fruit oil CO2 extract
FL/FR

safrole
CS

spicy carbonate
FR

sugandha kokila berry oil
FR

(E)-

tiglic acid
FL/FR

turmeric root absolute
FL/FR

zingerone
FL/FR

zingiber cassumunar rhizomes oil
FR

zingiber officinale root extract
FL/FR

zingiber officinale root tincture
FL/FR

terpenic

para-

cymene
FL/FR

frankincense oil
FL/FR

juniper branch oil
FR

pine needle oil dwarf
FL/FR

thujonic

common

tansy leaf oil dutch
FR

common

tansy oil canada
FR

beta-

thujone
FR

tonka

coumarin
FR

tonka bean absolute
FR

vanilla

ortho-

dimethyl hydroquinone
FL/FR

ethyl vanillin
FL/FR

ethyl vanillin hexylene glycol acetal
FR

vanilla bean absolute (vanilla planifolia)
FL/FR

vanilla cresol
FR

vanillin propylene glycol acetal
FL/FR

vanillyl acetate
FL/FR

waxy

ethyl laurate
FL/FR

woody

iso

caryophyllene
CS

caryophyllene alcohol acetate
FR

caryophyllene formate
FL/FR

beta-

caryophyllene oxide
FL/FR

atlas

cedarwood oil
FR

cedarwood oil virginia
FR

cistus twig/leaf oil
FL/FR

curcuma zedoaria bark extract
FL/FR

dacrydium franklinii wood oil
FR

frankincense resinoid
FL/FR

(E)-

germacrene D
FL/FR

guaiacwood oil
FL/FR

guaiacwood oil 20% in gurjun balsam oil
FR

guaiacyl acetate
FL/FR

hedychium spicatum root oil
FR

jatamansi root oil
FR

juniper berry oleoresin
FL/FR

longifolene
FL/FR

methyl cedryl ketone
FL/FR

methyl methylene tricyclodecanol
FR

patchouli absolute
FR

patchouli ethanone
FR

patchouli oil
FL/FR

4-iso

propyl phenol
FL/FR

rhubarb oxirane
FR

sabinene
FL/FR

santal penten-2-ol
FR

santall
FR

spicy pentanone
FL/FR

spikenard oil
FL/FR

spikenard oil CO2 extract
FL/FR

beta-

thujaplicin
FR

tobacarol (IFF)
FR

vetiver oil fractions
FR

woody acetate
FR

(Z)-

woody amylene
FR

woody propanol
FR

zedoary bark oil
FL/FR

zedoary root oil
FL/FR

zedoary root oil CO2 extract
FL/FR

For Flavor

No flavor group found for these

benzyl disulfide
FL

birch tar oil
FL/FR

alpha-

caryophyllene alcohol
FL/FR

caryophyllene formate
FL/FR

chavicol
FL

cistus ladaniferus resinoid
FL/FR

ortho-

cresyl isobutyrate
FL/FR

croton glabellus bark extract
FL/FR

2,4-

dihydroxybenzoic acid
FL

2,6-

dimethoxy-4-vinyl phenol
FL

ortho-

dimethyl hydroquinone
FL/FR

alpha-

ethoxy-ortho-cresol
FL/FR

eugenyl formate
FL/FR

(E)-

germacrene D
FL/FR

grains of paradise oil
FL/FR

guaiyl acetate
FL/FR

methyl crotonic acid
FL

methyl pyrrole
FL

methyl salicylaldehyde
FL

piperitenone
FL/FR

propyl phenol
FL/FR

para-

salicylic acid
FL

seaweed absolute (fucus vesiculosus et serratus)
FL/FR

spikenard oil
FL/FR

spikenard oil CO2 extract
FL/FR

animal

para-

cresyl caprylate
FL/FR

anise

anise seed oil colombia
FL/FR

aromatic

para-

cresyl acetate
FL/FR

balsamic

siam

benzoin resinoid
FL/FR

benzyl salicylate
FL/FR

laevo-

bornyl acetate
FL/FR

iso

butyl cinnamate
FL/FR

ethyl cinnamate
FL/FR

opoponax absolute (balsamodendron kafal)
FL/FR

berry

heliotropyl acetone
FL/FR

brown

(E)-

tiglic acid
FL/FR

burnt

4-iso

propyl phenol
FL/FR

2,6-

xylenol
FL/FR

caramellic

cyclotene
FL/FR

maltol
FL/FR

chemical

2,3-

dimethyl benzofuran
FL/FR

cherry

heliotropin
FL/FR

coconut

gamma-

nonalactone (aldehyde C-18 (so-called))
FL/FR

coffee

furfuryl mercaptan
FL/FR

cooling

iso

butyl salicylate
FL/FR

theaspirane
FL/FR

coumarinic

phthalide
FL/FR

creamy

para-

anisaldehyde
FL/FR

para-

vanillyl alcohol
FL/FR

fatty

10-

undecenal (aldehyde C-11 undecylenic)
FL/FR

fishy

penten-2-one
FL

floral

3,7-

dimethyl-6-octenoic acid
FL/FR

linalyl acetate
FL/FR

methyl phenyl acetate
FL/FR

phenethyl alcohol
FL/FR

fruity

para-

anisyl acetate
FL/FR

benzyl alcohol
FL/FR

dimethyl anthranilate
FL/FR

ethyl 3-hydroxyhexanoate
FL/FR

piper longum fruit oil CO2 extract
FL/FR

spicy pentanone
FL/FR

meta-

tolualdehyde
FL/FR

green

iso

amyl salicylate
FL/FR

angelica root oil
FL/FR

canarium luzonicum oil
FL/FR

para-

dimethyl hydroquinone
FL/FR

diphenyl oxide
FL/FR

immortelle absolute
FL/FR

oakmoss absolute
FL/FR

octanal diethyl acetal
FL/FR

herbal

anthemis nobilis flower oil roman
FL/FR

sweet

basil absolute
FL/FR

clary sage oil france
FL/FR

dihydroanethol
FL/FR

dill seed oil
FL/FR

dill seed oil CO2 extract
FL/FR

curled

parsley seed oil
FL/FR

petroselinum crispum seed oil CO2 extract
FL/FR

yerba mate absolute
FL/FR

honey

phenethyl phenyl acetate
FL/FR

lactonic

gamma-

heptalactone
FL/FR

gamma-

octalactone
FL/FR

leathery

castoreum absolute
FL/FR

meaty

allyl-2,6-dimethoxyphenol
FL

2,6-

dimethyl thiophenol
FL

ortho-

thioguaiacol
FL

medicinal

dextro-

camphor
FL/FR

2,6-

dimethoxyphenol
FL/FR

frankincense absolute
FL/FR

minty

iso

pulegol
FL/FR

(-)-iso

pulegol
FL/FR

musty

ethoxythiazole
FL

octanol
FL/FR

2,5-

xylenol
FL/FR

naphthyl

2'-

hydroxyacetophenone
FL/FR

nutty

nutty cyclohexenone
FL/FR

onion

methyl-1,3-dithiolane
FL

phenolic

methyl benzoate
FL/FR

phenyl pyruvic acid
FL/FR

thymol
FL/FR

vinyl phenol
FL/FR

2,3-

xylenol
FL/FR

pine

pine needle oil dwarf
FL/FR

powdery

ortho-

acetanisole
FL/FR

rummy

vanillyl ethyl ether
FL/FR

smoky

ethyl phenol
FL/FR

prosopis juliflora wood extract
FL

pyroligneous acids
FL/FR

pyroligneous acids hickory
FL/FR

dextro-

xylose
FL

soapy

dodecanal (aldehyde C-12 lauric)
FL/FR

solvent

methyl phenyl sulfide
FL

2-iso

propyl phenol
FL/FR

spicy

allspice berry absolute
FL/FR

allspice oil
FL/FR

artemisia dracunculus herb oil
FL/FR

sumatra

benzoin absolute
FL/FR

benzyl isoeugenol
FL/FR

carvacrol
FL/FR

beta-

caryophyllene
FL/FR

cascarilla oil replacer
FL/FR

cassia bark oil china
FL/FR

cassia leaf oil
FL/FR

cinnamon bark oil
FL/FR

cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR

cinnamon bark oil ceylon
FL/FR

cinnamon leaf oil ceylon
FL/FR

cinnamon oleoresin ceylon
FL/FR

clove bud absolute
FL/FR

clove bud oil
FL/FR

clove bud oil CO2 extract
FL/FR

croton eluteria bark oil
FL/FR

para-alpha-

dimethyl styrene
FL/FR

eugenol
FL/FR

iso

eugenyl acetate
FL/FR

galangal root oil
FL/FR

ginger oleoresin africa
FL/FR

ginger root oil brazil
FL/FR

ginger root oil china
FL/FR

mace absolute
FL/FR

mace oil
FL/FR

ortho-

methoxycinnamaldehyde
FL/FR

alpha-

methyl cinnamaldehyde
FL/FR

methyl cinnamate
FL/FR

methyl guaiacol
FL/FR

methyl isoeugenol
FL/FR

myristica fragrans fruit extract
FL/FR

myristica fragrans seed tincture
FL/FR

nutmeg oil
FL/FR

black

pepper absolute
FL/FR

black

pepper oil CO2 extract
FL/FR

white

pepper oleoresin
FL

pepper tree berry absolute
FL/FR

pepper tree berry oil
FL/FR

pepper tree berry oil CO2 extract
FL/FR

phenyl propyl alcohol
FL/FR

piper longum fruit oil
FL/FR

para-iso

propyl acetophenone
FL/FR

para-

tolualdehyde
FL/FR

turmeric oleoresin
FL

turmeric root absolute
FL/FR

zingerone
FL/FR

zingiber officinale root extract
FL/FR

zingiber officinale root tincture
FL/FR

terpenic

para-

cymene
FL/FR

vanilla

ethyl vanillin
FL/FR

vanilla bean absolute (vanilla planifolia)
FL/FR

vanillin propylene glycol acetal
FL/FR

vanillyl acetate
FL/FR

vegetable

tyramine
FL

waxy

ethyl laurate
FL/FR

alpha-

hexyl cinnamaldehyde
FL/FR

mimosa absolute
FL/FR

mimosa absolute france
FL/FR

mimosa absolute india
FL/FR

woody

ambroxan
FL/FR

amyris wood oil
FL/FR

iso

bornyl acetate
FL/FR

beta-

caryophyllene oxide
FL/FR

cistus twig/leaf oil
FL/FR

curcuma zedoaria bark extract
FL/FR

ethyl guaiacol
FL/FR

frankincense oil
FL/FR

frankincense resinoid
FL/FR

ortho-

guaiacol
FL/FR

guaiacwood oil
FL/FR

guaiacyl acetate
FL/FR

juniper berry oleoresin
FL/FR

longifolene
FL/FR

methyl cedryl ketone
FL/FR

patchouli oil
FL/FR

sabinene
FL/FR

safranal
FL/FR

zedoary bark oil
FL/FR

zedoary root oil
FL/FR

zedoary root oil CO2 extract
FL/FR

Potential Uses:

FL	bacon
FL	horseradish
FL	salmon smoked salmon
FL	smoke
FR	spice
FR	vanilla
FR	woody

Occurrence (nature, food, other):note

	apple fruit Search PMC Picture
	celery Search Trop Picture
	cheese gruyere cheese Search PMC Picture
	cheese swiss chesse Search PMC Picture
	cider Search PMC Picture
	cocoa Search Trop Picture
	elderberry fruit juice Search Trop Picture
	fish lean fish Search PMC Picture
	grape juice Search PMC Picture
	honey Search PMC Picture
	katsuobushi Search PMC Picture
	orange fruit juice Search Trop Picture
	plum fruit Search Trop Picture
	pork Search PMC Picture
	scallop Search PMC Picture
	soybean Search Trop Picture
	strawberry wild strawberry fruit Search Trop Picture
	wine Search Picture

Synonyms:

p-	cresol, 2,6-dimethoxy-
3,5-	dimethoxy-4-hydroxytoluene
2,6-	dimethoxy-4-methyl phenol
2,6-	dimethoxy-4-methylphenol
2,6-	dimethoxy-p-cresol
2,6-	dimethoxy-para-cresol
4-	hydroxy-3,5-dimethoxytoluene
4-	methyl syringol
1-	methyl-3,5-dimethoxy-4-hydroxybenzene
4-	methylsyringol
	phenol, 2,6-dimethoxy-4-methyl-

Articles:

PubMed:Determination of the importance of in-mouth release of volatile phenol glycoconjugates to the flavor of smoke-tainted wines.

PubMed:Characterisation of volatile compounds in a smoke flavouring from rice husk.

PubMed:Ultraviolet spectroscopy of fundamental lignin subunits: guaiacol, 4-methylguaiacol, syringol, and 4-methylsyringol.

PubMed:Determination of Eucalyptus spp lignin S/G ratio: a comparison between methods.

PubMed:Measurement of urinary methoxyphenols and their use for biological monitoring of wood smoke exposure.

Notes:

Present in smoked fish and pork. Flavouring ingredient

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4-methyl-2,6-dimethoxyphenol 2,6-dimethoxy-p-cresol

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4-methyl-2,6-dimethoxyphenol
2,6-dimethoxy-p-cresol