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caryophyllene
4,11,11-trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene

Supplier Sponsors

Berjé

Where the world comes to its senses
Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
Email:	For Information
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Product(s):
Caryophyllene

Hermitage Oils

Hermitage Oils / Neroli S.R.L.

Perfumery and Aromatherapy materials since 1979
Hermitage Oils, the true home of essential oils!
Hermitage Oils offers a selection of Absolutes, Essential Oils, Natural Isolates, Aroma Chemicals, CO2 Extracts, Ethanol Tinctures, and Extraits by Enfleurage.
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Product(s):
Caryophyllene Natural Isolate
Joseph Colbourne has this to say about Caryophyllene (Clove Bud Fractions) “A clear, watery liquid material, caryophyllene is softly spicy, woody, dry, and elegant. The isolate is that sparkle in the scent profiles of clove, pepper, and also many florals. Facets of cananga, cinnamon, calamus and copaiba can be detected by my nose. The dry down presents a pleasantly musty driftwood note. While there is an ostensibly tenacious open, the longevity is only about 3-4 hours, making this unmistakably a top note. The true value of caryophyllene perhaps isn’t its scent alone but what it does in accenting and building florals and woods that may need more dimension and diffusion. Therefore, it would be an excellent way to open a fragrance.”

Riverside Aromatics

Riverside Aromatics Ltd.

Speciality Aroma Chemicals, Naturals and Synthetics
A specialist supplier of raw materials to the flavour industry.
Peter Cannon & David Rowe established Riverside Aromatics in 2006 in Poole, UK, to offer a new type of specialist raw material supplier to the Flavour & Fragrance Industry. We bring together over 40 years of commercial & technical experience in the F&F industry which allows us to understand the needs of the Global F&F business and especially that of the West European Market.
Email:	Info
Email:	Peter Cannon (sales)
Voice: +44 (0) 1202 679532
Fax: +44 (0) 1202 679532
Products List:	View
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Product(s):
NC3500 CARYOPHYLLENE, NATURAL

R C Treatt & Co Ltd

R C Treatt and Co Ltd

Innovative ingredient solutions
World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
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US Voice: +1 863 668 9500
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Product(s):
Caryophyllene

Zanos

Distributor of Speciality Chemicals and Natural Ingredients
Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.
The flavour and fragrance industry's premier source for aroma chemicals and essential oils
Zanos Ltd. is a B2B supplier of aroma chemicals, speciality chemicals, natural ingredients and vitamins to a diverse range of customers. In Autumn 2020, Stort Chemicals Limited completed their acquisition of Zanos Ltd. Combining our strengths, Stort and Zanos have boosted our respective portfolios of aroma chemicals, speciality chemicals and natural ingredients. With warehousing facilities across the UK, Rotterdam and Hamburg, Zanos is perfectly positioned to dispatch product throughout Europe.
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Product(s):
CARYOPHYLLENE (natural isolated constituent)

Name:	(4Z)-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene
CAS Number:	13877-93-5	3D/inchi
Other(deleted CASRN):	101365-34-8
FDA UNII:	Search
Nikkaji Web:	J101.611C
MDL:	MFCD00075925
CoE Number:	2618
XlogP3-AA:	4.40 (est)
Molecular Weight:	204.35628000
Formula:	C15 H24
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:flavor and fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
FEMA Number:	2252 caryophyllene
FDA:	No longer provide for the use of these seven synthetic flavoring substances

Physical Properties:

Appearance:	colorless to pale yellow clear oily liquid (est)
Assay:	92.00 to 100.00 sum of isomers
Food Chemicals Codex Listed:	No
Specific Gravity:	0.89700 to 0.91000 @ 25.00 °C.
Pounds per Gallon - (est).:	7.464 to 7.572
Refractive Index:	1.49800 to 1.50400 @ 20.00 °C.
Optical Rotation:	-5.00 to -10.00
Boiling Point:	129.00 to 130.00 °C. @ 14.00 mm Hg
Boiling Point:	254.00 to 257.00 °C. @ 760.00 mm Hg
Vapor Pressure:	0.013000 mmHg @ 25.00 °C. (est)
Flash Point:	205.00 °F. TCC ( 96.11 °C. )
logP (o/w):	6.777 (est)
Soluble in:
	alcohol
	water, 0.05011 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor Type: spicy

Odor Strength:medium

Substantivity:44 hour(s) at 100.00 %

sweet woody spicy clove dry

Odor Description:at 100.00 %. sweet woody spice clove dry

spicy woody terpenic

Odor Description:Spicy, woody and terpenic
Mosciano, Gerard P&F 17, No. 4, 33, (1992)

Flavor Type: spicy

spicy peppery woody camphoreous citrus

Taste Description: at 50.00 ppm. Spicy pepper-like, woody, camphoraceous, with a citrus background
Mosciano, Gerard P&F 17, No. 4, 33, (1992)

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Creatingperfume.com

Odor: Sweet, woody, spice, clove, dry, terpenic

Caryophyllene Natural Isolate

Odor: characteristic

Use: Joseph Colbourne has this to say about Caryophyllene (Clove Bud Fractions) “A clear, watery liquid material, caryophyllene is softly spicy, woody, dry, and elegant. The isolate is that sparkle in the scent profiles of clove, pepper, and also many florals. Facets of cananga, cinnamon, calamus and copaiba can be detected by my nose. The dry down presents a pleasantly musty driftwood note. While there is an ostensibly tenacious open, the longevity is only about 3-4 hours, making this unmistakably a top note. The true value of caryophyllene perhaps isn’t its scent alone but what it does in accenting and building florals and woods that may need more dimension and diffusion. Therefore, it would be an excellent way to open a fragrance.”

K.L. Koh Enterprise

Natura Aromatik

R C Treatt & Co Ltd

Riverside Aromatics

CARYOPHYLLENE, NATURAL

CARYOPHYLLENE (natural isolated constituent)

Safety Information:

European information :
Most important hazard(s):
Xn - Harmful.
R 38 - Irritating to skin. R 65 - Harmful: may cause lung damage if swallowed. S 02 - Keep out of the reach of children. S 36 - Wear suitable protective clothing. S 62 - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for caryophyllene usage levels up to:
	8.0000 % in the fragrance concentrate.

Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		-	27.00000
beverages(nonalcoholic):		-	14.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	200.00000
condiments / relishes:		-	50.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	2.00000
fruit ices:		-	2.00000
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	34.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):13877-93-5

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :5322111

National Institute of Allergy and Infectious Diseases:Data

(4Z)-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene

Chemidplus:0013877935

RTECS:DT8400000 for cas# 13877-93-5

References:

	(4Z)-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	5322111
Pubchem (sid):	134990092

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2902.19.1000
Typical G.C.
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

For Odor

No odor group found for these

atractylis absolute
FR

aldehydic

aldehydic

2-

methyl undecanal (aldehyde C-12 mna)
FL/FR

nonanal (aldehyde C-9)
FL/FR

10-

undecenal (aldehyde C-11 undecylenic)
FL/FR

amber

amber carane
FR

angelica seed oil CO2 extract
FL/FR

cistus ladaniferus resinoid
FL/FR

animal

musk indenofuran
FR

anise

estragon absolute
FR

sweet

fennel seed oil
FL/FR

anisic

para-

anisaldehyde
FL/FR

dihydroanethol
FL/FR

balsamic

abies alba needle oil
FL/FR

2-

acetyl furan
FL/FR

iso

amyl benzoate
FL/FR

amyris wood oil
FL/FR

siam

benzoin resinoid
FL/FR

bornyl acetate
FL/FR

iso

bornyl acetate
FL/FR

iso

bornyl propionate
FL/FR

iso

butyl cinnamate
FL/FR

cinnamyl alcohol
FL/FR

clover nitrile
FR

copaiba balsam oil
FL/FR

croton glabellus bark extract
FL/FR

ethyl cinnamate
FL/FR

guaiyl acetate
FL/FR

methyl (E)-cinnamate
FL/FR

myrrh resinoid
FR

opoponax absolute (balsamodendron kafal)
FL/FR

3-

phenyl propyl alcohol
FL/FR

valeriana wallichii root oil
FR

berry

raspberry ketone
FL/FR

buttery

caramellic

immortelle absolute
FL/FR

maltol
FL/FR

chocolate

iso

amyl phenyl acetate
FL/FR

chocolate pyrazine A
FL/FR

citrus

bergamot oil bergaptene reduced italy
FL/FR

grapefruit oil folded california
FL/FR

grapefruit oil folded florida
FL/FR

blood

orange oil italy
FL/FR

sweet

orange peel oil c.p. brazil
FL/FR

coconut

gamma-

nonalactone (aldehyde C-18 (so-called))
FL/FR

fatty

coconut absolute
FL/FR

floral

acetophenone
FL/FR

alpha-

amyl cinnamaldehyde
FL/FR

iso

amyl salicylate
FL/FR

benzyl acetate
FL/FR

bois de rose oil brazil
FL/FR

cassis specialty
FR

cestrum nocturnum flower absolute
FR

citronellol
FL/FR

coriander seed oil
FL/FR

cyclohexyl ethyl alcohol
FL/FR

dihydrojasmone
FL/FR

dimethyl benzyl carbinyl butyrate
FL/FR

floral pyranol
FR

geranium oil bourbon
FL/FR

heliotropin
FL/FR

heliotropyl acetone
FL/FR

heliotropyl diethyl acetal
FR

(Z)-3-

hexen-1-yl salicylate
FL/FR

alpha-

hexyl cinnamaldehyde
FL/FR

karo karounde absolute
FR

laevo-

linalool oxide
FL/FR

mimosa absolute
FL/FR

mimosa absolute france
FL/FR

mimosa absolute india
FL/FR

nerol
FL/FR

ocean propanal
FL/FR

orris pyridine 25% IPM
FR

palmarosa oil
FL/FR

peony alcohol
FR

petitgrain oil paraguay
FL/FR

phenethyl acetate
FL/FR

phenethyl alcohol
FL/FR

phenethyl salicylate
FL/FR

rose butanoate
FL/FR

rose concrete (rosa centifolia)
FR

tetrahydrolinalool
FL/FR

violet methyl carbonate
FR

fruity

allyl amyl glycolate
FR

allyl cyclohexyl propionate
FL/FR

gamma-

decalactone
FL/FR

dimethyl benzyl carbinyl isobutyrate
FR

2-

phenyl propyl butyrate
FL/FR

green

(Z)-3-

hexen-1-yl benzoate
FL/FR

narcissus flower absolute
FR

octanal diethyl acetal
FL/FR

hay

beeswax absolute
FL/FR

herbal

acorus calamus rhizome oil
FR

sweet

basil absolute
FL/FR

calamintha clinopodium oil
FR

canarium luzonicum gum
FL/FR

canarium luzonicum oil
FL/FR

carum carvi fruit oil
FL/FR

clary sage oil france
FL/FR

costmary oil (chrysanthemum balsamita)
FR

dill seed oil
FL/FR

dill seed oil CO2 extract
FL/FR

geranic oxide
FL/FR

6-

hydroxydihydrotheaspirane (mixture of isomers)
FL/FR

abrialis

lavandin oil
FL/FR

lavender absolute bulgaria
FL/FR

linalyl acetate
FL/FR

nonisyl acetate
FR

curled

parsley seed oil
FL/FR

petroselinum crispum seed oil CO2 extract
FL/FR

pinocarveol
FL/FR

sabinene hydrate
FL/FR

common

tansy flower oil
FR

common

tansy flower oil dutch
FR

minty

dextro-

dihydrocarvone
FL/FR

mossy

treemoss absolute
FR

veramoss (IFF)
FR

musk

musk indanone
FR

naphthyl

beta-

naphthyl ethyl ether
FL/FR

orris

iso

eugenyl formate
FL/FR

eugenyl formate
FL/FR

para-iso

propyl acetophenone
FL/FR

peppery

asarum europaeum oil
FR

phenolic

4-

methyl-2,6-dimethoxyphenol
FL/FR

powdery

para-

anisyl acetate
FL/FR

para-

anisyl alcohol
FL/FR

saffron

saffron stigmates absolute
FR

spicy

allspice berry absolute
FL/FR

allspice leaf oil
FL/FR

allspice oil
FL/FR

angelica seed absolute
FL/FR

anona squamosa leaf oil
FR

artemisia dracunculus herb oil
FL/FR

ayou wood oil
FR

benzyl isoeugenol
FL/FR

carnation absolute
FR

beta-

caryophyllene
FL/FR

alpha-

caryophyllene alcohol
FL/FR

cascarilla oil replacer
FL/FR

cassia bark oil china
FL/FR

cassia leaf oil
FL/FR

cinnamon bark oil
FL/FR

cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR

cinnamon bark oil ceylon
FL/FR

cinnamon leaf oil ceylon
FL/FR

cinnamon oleoresin ceylon
FL/FR

clove bud absolute
FL/FR

clove bud oil CO2 extract
FL/FR

clove leaf oil
FL/FR

cubeb oil CO2 extract (piper cubeba)
FL/FR

black

currant bud absolute
FL/FR

elettaria cardamomum seed oil
FL/FR

iso

eugenyl acetate
FL/FR

eugenyl acetate
FL/FR

galangal root oil
FL/FR

ginger oleoresin africa
FL/FR

ginger root oil brazil
FL/FR

ginger root oil china
FL/FR

grains of paradise oil
FL/FR

mace absolute
FL/FR

machilus kusanoi leaf oil
FR

machilus kusanoi wood oil
FR

maja fragrance
FR

alpha-

methyl cinnamaldehyde
FL/FR

methyl eugenol
FR

methyl isoeugenol
FL/FR

myristica fragrans fruit extract
FL/FR

myristica fragrans seed tincture
FL/FR

nutmeg oil
FL/FR

black

pepper absolute
FL/FR

pepper hexanone
FR

black

pepper oil CO2 extract
FL/FR

pepper tree berry absolute
FL/FR

pepper tree berry oil
FL/FR

pepper tree berry oil CO2 extract
FL/FR

pimenta acris leaf oil
FL/FR

piper longum fruit oil
FL/FR

piper longum fruit oil CO2 extract
FL/FR

spicy carbonate
FR

sugandha kokila berry oil
FR

(E)-

tiglic acid
FL/FR

turmeric root absolute
FL/FR

zingiber officinale root extract
FL/FR

zingiber officinale root tincture
FL/FR

zvoulimba leaf oil
FR

terpenic

angelica seed oil
FL/FR

para-

cymene
FL/FR

elemi resinoid
FL/FR

frankincense oil
FL/FR

juniper branch oil
FR

pine needle oil dwarf
FL/FR

alpha-

terpineol
FL/FR

thujonic

common

tansy leaf oil dutch
FR

common

tansy oil canada
FR

beta-

tonka

deertongue absolute
FR

tonka bean absolute
FR

vanilla

ethyl vanillin
FL/FR

vanilla bean absolute (vanilla planifolia)
FL/FR

vanilla cresol
FR

vanillyl acetate
FL/FR

waxy

1-

undecanol
FL/FR

woody

iso

bornyl isovalerate
FL/FR

caryophyllene alcohol acetate
FR

caryophyllene formate
FL/FR

beta-

caryophyllene oxide
FL/FR

curcuma zedoaria bark extract
FL/FR

dacrydium franklinii wood oil
FR

guaiacwood oil
FL/FR

guaiacwood oil 20% in gurjun balsam oil
FR

guaiacyl acetate
FL/FR

gurjun balsam oil
FR

hedychium spicatum root oil
FR

jatamansi root oil
FR

juniper berry oleoresin
FL/FR

methyl cedryl ketone
FL/FR

methyl methylene tricyclodecanol
FR

patchouli absolute
FR

patchouli ethanone
FR

patchouli oil
FL/FR

4-iso

propyl phenol
FL/FR

rhubarb oxirane
FR

santal penten-2-ol
FR

spikenard oil
FL/FR

spikenard oil CO2 extract
FL/FR

tobacarol (IFF)
FR

woody acetate
FR

(Z)-

woody amylene
FR

woody propanol
FR

zedoary bark oil
FL/FR

zedoary root oil
FL/FR

zedoary root oil CO2 extract
FL/FR

For Flavor

No flavor group found for these

alpha-

caryophyllene alcohol
FL/FR

caryophyllene formate
FL/FR

chocolate pyrazine A
FL/FR

cistus ladaniferus resinoid
FL/FR

croton glabellus bark extract
FL/FR

eugenyl formate
FL/FR

iso

eugenyl formate
FL/FR

grains of paradise oil
FL/FR

guaiyl acetate
FL/FR

methyl (E)-cinnamate
FL/FR

spikenard oil
FL/FR

spikenard oil CO2 extract
FL/FR

aldehydic

aldehydic

nonanal (aldehyde C-9)
FL/FR

1-

undecanol
FL/FR

amber

angelica seed oil
FL/FR

anise

sweet

fennel seed oil
FL/FR

balsamic

siam

benzoin resinoid
FL/FR

iso

bornyl propionate
FL/FR

iso

butyl cinnamate
FL/FR

copaiba balsam oil
FL/FR

ethyl cinnamate
FL/FR

opoponax absolute (balsamodendron kafal)
FL/FR

berry

heliotropyl acetone
FL/FR

raspberry ketone
FL/FR

brown

beeswax absolute
FL/FR

(E)-

tiglic acid
FL/FR

burnt

4-iso

propyl phenol
FL/FR

camphoreous

bornyl acetate
FL/FR

geranic oxide
FL/FR

6-

hydroxydihydrotheaspirane (mixture of isomers)
FL/FR

pinocarveol
FL/FR

caramellic

maltol
FL/FR

cherry

heliotropin
FL/FR

citrus

bergamot oil bergaptene reduced italy
FL/FR

grapefruit oil folded california
FL/FR

grapefruit oil folded florida
FL/FR

laevo-

nerol
FL/FR

blood

orange oil italy
FL/FR

sweet

orange peel oil c.p. brazil
FL/FR

alpha-

terpineol
FL/FR

coconut

gamma-

nonalactone (aldehyde C-18 (so-called))
FL/FR

cooling

sabinene hydrate
FL/FR

creamy

para-

anisaldehyde
FL/FR

fatty

coconut absolute
FL/FR

(Z)-3-

hexen-1-yl benzoate
FL/FR

10-

undecenal (aldehyde C-11 undecylenic)
FL/FR

floral

iso

amyl phenyl acetate
FL/FR

bois de rose oil brazil
FL/FR

citronellol
FL/FR

dihydrojasmone
FL/FR

dimethyl benzyl carbinyl butyrate
FL/FR

geranium oil bourbon
FL/FR

linalyl acetate
FL/FR

ocean propanal
FL/FR

phenethyl alcohol
FL/FR

tetrahydrolinalool
FL/FR

fruity

allyl cyclohexyl propionate
FL/FR

iso

amyl benzoate
FL/FR

para-

anisyl acetate
FL/FR

para-

anisyl alcohol
FL/FR

benzyl acetate
FL/FR

gamma-

decalactone
FL/FR

piper longum fruit oil CO2 extract
FL/FR

rose butanoate
FL/FR

grassy

palmarosa oil
FL/FR

green

iso

amyl salicylate
FL/FR

canarium luzonicum gum
FL/FR

canarium luzonicum oil
FL/FR

cinnamyl alcohol
FL/FR

cyclohexyl ethyl alcohol
FL/FR

dextro-

dihydrocarvone
FL/FR

elemi resinoid
FL/FR

(Z)-3-

hexen-1-yl salicylate
FL/FR

immortelle absolute
FL/FR

linalool oxide
FL/FR

octanal diethyl acetal
FL/FR

herbal

angelica seed oil CO2 extract
FL/FR

sweet

basil absolute
FL/FR

carum carvi fruit oil
FL/FR

clary sage oil france
FL/FR

coriander seed oil
FL/FR

dihydroanethol
FL/FR

dill seed oil
FL/FR

dill seed oil CO2 extract
FL/FR

abrialis

lavandin oil
FL/FR

lavender absolute bulgaria
FL/FR

curled

parsley seed oil
FL/FR

petitgrain oil paraguay
FL/FR

petroselinum crispum seed oil CO2 extract
FL/FR

honey

phenethyl acetate
FL/FR

medicinal,

phenethyl salicylate
FL/FR

nutty

2-

acetyl furan
FL/FR

phenolic

4-

methyl-2,6-dimethoxyphenol
FL/FR

pine

pine needle oil dwarf
FL/FR

powdery

acetophenone
FL/FR

beta-

naphthyl ethyl ether
FL/FR

smoky

prosopis juliflora wood extract
FL

solvent

methyl phenyl sulfide
FL

spicy

allspice berry absolute
FL/FR

allspice leaf oil
FL/FR

allspice oil
FL/FR

angelica seed absolute
FL/FR

artemisia dracunculus herb oil
FL/FR

benzyl isoeugenol
FL/FR

benzylidene acetone
FL

beta-

caryophyllene
FL/FR

cascarilla oil replacer
FL/FR

cassia bark oil china
FL/FR

cassia leaf oil
FL/FR

chipotle chili distillates
FL

chipotle chili oleoresin
FL

cinnamon bark oil
FL/FR

cinnamon bark oil (cinnamomum zeylanicum) india
FL/FR

cinnamon bark oil ceylon
FL/FR

cinnamon leaf oil ceylon
FL/FR

cinnamon oleoresin ceylon
FL/FR

clove bud absolute
FL/FR

clove bud oil CO2 extract
FL/FR

clove leaf oil
FL/FR

cubeb oil CO2 extract (piper cubeba)
FL/FR

black

currant bud absolute
FL/FR

elettaria cardamomum seed oil
FL/FR

eugenyl acetate
FL/FR

iso

eugenyl acetate
FL/FR

galangal root oil
FL/FR

ginger oleoresin africa
FL/FR

ginger root oil brazil
FL/FR

ginger root oil china
FL/FR

jalapeno oleoresin
FL

mace absolute
FL/FR

alpha-

methyl cinnamaldehyde
FL/FR

methyl isoeugenol
FL/FR

myristica fragrans fruit extract
FL/FR

myristica fragrans seed tincture
FL/FR

nutmeg oil
FL/FR

black

pepper absolute
FL/FR

black

pepper oil CO2 extract
FL/FR

white

pepper oleoresin
FL

pepper tree berry absolute
FL/FR

pepper tree berry oil
FL/FR

pepper tree berry oil CO2 extract
FL/FR

3-

phenyl propyl alcohol
FL/FR

2-

phenyl propyl butyrate
FL/FR

pimenta acris leaf oil
FL/FR

piper longum fruit oil
FL/FR

para-iso

propyl acetophenone
FL/FR

turmeric oleoresin
FL

turmeric root absolute
FL/FR

zingiber officinale root extract
FL/FR

zingiber officinale root tincture
FL/FR

terpenic

abies alba needle oil
FL/FR

para-

cymene
FL/FR

tropical

alpha-

amyl cinnamaldehyde
FL/FR

vanilla

ethyl vanillin
FL/FR

vanilla bean absolute (vanilla planifolia)
FL/FR

vanillyl acetate
FL/FR

waxy

alpha-

hexyl cinnamaldehyde
FL/FR

2-

methyl undecanal (aldehyde C-12 mna)
FL/FR

mimosa absolute
FL/FR

mimosa absolute france
FL/FR

mimosa absolute india
FL/FR

woody

amyris wood oil
FL/FR

iso

bornyl acetate
FL/FR

iso

bornyl isovalerate
FL/FR

beta-

caryophyllene oxide
FL/FR

curcuma zedoaria bark extract
FL/FR

frankincense oil
FL/FR

guaiacwood oil
FL/FR

guaiacyl acetate
FL/FR

juniper berry oleoresin
FL/FR

methyl cedryl ketone
FL/FR

patchouli oil
FL/FR

zedoary bark oil
FL/FR

zedoary root oil
FL/FR

zedoary root oil CO2 extract
FL/FR

Potential Uses:

FR	acacia
FR	agate
FR	allspice
FR	almond
FR	angel essence
FL	artichoke
FR	balsam
FR	bayberry
FL/FR	benzoin absolute replacer
FR	betel
FR	bouquet
FL/FR	caraway seed
FR	carnation
FL	carrot
FR	cassia
FR	christmas
FR	chypre
FR	cinnamon
FR	cinnamon
FR	citrus
FR	citrus
FR	clove
FR	clove
FL/FR	copaiba balsam
FR	floral
FR	florida breeze
FR	forest
FR	greenhouse
FR	guava
FR	heliotrope
FR	herbal
FR	herbal
FR	hollyberry
FR	honeysuckle
FR	hovenia
	huile de mille fleurs
FR	hyacinth
FR	incense
FR	jasmin
	jockey club
FR	lavender
FR	lilac
FR	maja
FR	millefleurs
FR	mint
FR	mint
FR	musk
FR	musk
FR	narcissus
FR	narcissus
FR	nutmeg
FR	opoponax
FR	oriental
FR	patchouli
FR	pepper
FR	pine
FR	pine forest
FR	rose
FR	rose
FR	sandalwood
FR	sandalwood
FR	sassafras
FR	spearmint
FR	spice
FR	spice
FR	spring rain
FR	sweet pea
FR	vanilla
FR	verbena
FR	windsor soap
FR	wisteria
FR	woody
FR	woody
FR	ylang ylang

Occurrence (nature, food, other):note

	alpinia galanga oil @ 0.90% Data GC Search Trop Picture
	cedrela wood oil @ 1.20% Data GC Search Trop Picture
	cinnamon bark oil (cinnamomum zeylanicum blume) sri lauka @ trace-0.12% Data GC Search Trop Picture
	galangal root oil @ 0.40% Data GC Search Trop Picture
	juniper berry oil @ 2.70% Data GC Search Trop Picture
	lavandin water (lavandula hydrida) @ 0.10% Data GC Search Trop Picture
	lavender spike water @ 0.07% Data GC Search Trop Picture
	lavender water bulgaria @ 0.07% Data GC Search Trop Picture
	mikan peel oil @ 0.07% Data GC Search Trop Picture
	ravintsara leaf oil @ 3.54%% Data GC Search PMC Picture
	salvia plebeia oil @ 0.88% Data GC Search Trop Picture
	tejpat oil @ 0.70% Data GC Search Trop Picture

Synonyms:

	bicyclo(7.2.0)undec-4-ene, 4,11,11-trimethyl-8-methylene-
	bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene-
.gamma.-	caryophyllene
	caryophyllene (natural)
	caryophyllene 100% (ex clove bud)
	caryophyllene alpha + beta mixture
	caryophyllene ex terp
	caryophyllene FCC
	caryophyllene natural isolate
	caryophyllene pure natural
8-	methylene-4,11,11-(trimethyl) bicyclo(7.2.0)undec-4-ene
2-	methylene-6,10,10-trimethyl bicyclo 7.2.0 undec-5-ene
(4Z)-4,11,11-	trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene
4,11,11-	trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene

Articles:

US Patents:3,965,189 - 1-Acetyl-11-methylene-4,7,7-trimethyl-cycloundeca-4,8-diene

PubMed:trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α.

US Patents:Sesquiterpenic derivatives as odor- and taste modifying agents

PubMed:High-density biosynthetic fuels: the intersection of heterogeneous catalysis and metabolic engineering.

PubMed:Chemical description and essential oil yield variability of different accessions of Salvia lavandulifolia.

PubMed:Comparison of volatile compounds with characteristic odor in flowers and leaves of nojigiku (Chrysanthemum japonense).

PubMed:Use of hydrodistillation and headspace solid-phase microextraction to characterize the volatile composition of different hop cultivars.

PubMed:Characteristic odor components of essential oil from Scutellaria laeteviolacea.

PubMed:Volatiles profiling in medicinal licorice roots using steam distillation and solid-phase microextraction (SPME) coupled to chemometrics.

PubMed:Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O).

PubMed:Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.

PubMed:Flavor characterization of sugar-added pennywort (Centella asiatica L.) juices treated with ultra-high pressure and thermal processes.

PubMed:Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf.

PubMed:Chemical compositions and antioxidant/antimicrobial activities of various samples prepared from Schinus terebinthifolius leaves cultivated in Egypt.

PubMed:Comparative analysis of essential oils from eight herbal medicines with pungent flavor and cool nature by GC-MS and chemometric resolution methods.

PubMed:Terpene biosynthesis in glandular trichomes of hop.

PubMed:Improvement of texture properties and flavor of frozen dough by carrot (Daucus carota) antifreeze protein supplementation.

PubMed:Volatile constituents in the flowers of Elsholtzia argyi and their variation: a possible utilization of plant resources after phytoremediation.

PubMed:Volatile constituents and key odorants in leaves, buds, flowers, and fruits of Laurus nobilis L.

PubMed:Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.

PubMed:Chemical composition, toxicity and mosquito repellency of Ocimum selloi oil.

PubMed:Changes of the volatile profile and artifact formation in Daidai (Citrus aurantium) cold-pressed peel oil on storage.

PubMed:Engineering a mevalonate pathway in Escherichia coli for production of terpenoids.

PubMed:Characterization of volatiles in Costa Rican guava [Psidium friedrichsthalianum (Berg) Niedenzu] fruit.

PubMed:Characterization of volatiles in strawberry guava (Psidium cattleianum Sabine) fruit.

PubMed:Determination of Key Flavor Components in Methylene Chloride Extracts from Processed Grapefruit Juice.

PubMed:Aroma-active compounds of miniature beefsteakplant (Mosla dianthera Maxim).

PubMed:Flavor compounds of pine sprout tea and pine needle tea.

Notes:

None found

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