para-salicylic acid
4-hydroxybenzoic acid

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  Beijing Lys Chemicals Co, LTD.

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  BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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  BOC Sciences

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  99-96-7 4-Hydroxybenzoic acid 98%

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  Charkit Chemical Corporation

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  about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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  HYDROXYBENZOIC ACID,4- PURIFIED CLEAN ROOM
  HYDROXYBENZOIC ACID, P- POLYMER GRADE

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  Penta International Corporation

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  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  08-57000 p-HYDROXYBENZOIC ACID

• 
  Prodasynth

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  Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.
  Today we are also proud to say, we have created an important range of Natural Molecules which can be found in our Raw Material Compendium. The versatility of our small but efficient structure is one of our main strengths when trying to fulfill our clients' requirements.
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  PARA-HYDROXYBENZOIC ACID (> 99%)

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  Sigma-Aldrich

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  Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
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  W398608 4-Hydroxybenzoic acid, ≥99%, FG
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  TCI AMERICA

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  Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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  H0207 4-Hydroxybenzoic Acid >99.0%(GC)(T)
  SDS

Name: 4-hydroxybenzoic acid CAS Number: 99-96-7 3D/inchi ECHA EINECS - REACH Pre-Reg: 202-804-9 FDA UNII: JG8Z55Y12H Nikkaji Web: J43.201F Beilstein Number: 0970950 MDL: MFCD00002547 CoE Number: 693 XlogP3: 1.60 (est) Molecular Weight: 138.12242000 Formula: C7 H6 O3 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:flavoring agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 957 4-hydroxybenzoic acid DG SANTE Food Flavourings: 08.040 4-hydroxybenzoic acid DG SANTE Food Contact Materials: 4-hydroxybenzoic acid FEMA Number: 3986 4-hydroxybenzoic acid FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 99-96-7 ; 4-HYDROXYBENZOIC ACID   Physical Properties: Appearance: white powder (est) Assay: 99.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 213.00 to 215.00 °C. @ 760.00 mm Hg Boiling Point: 334.00 to 335.00 °C. @ 760.00 mm Hg Flash Point: > 212.00 °F. TCC ( > 100.00 °C. ) logP (o/w): 1.580 Soluble in:   alcohol   water, 1.45e+004 mg/L @ 25 °C (est) Insoluble in:   water   Organoleptic Properties: Odor Type: phenolic phenolic nutty Odor Description:at 100.00 %. phenolic nutty Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: preservatives   Suppliers: Alfa Biotechnology For experimental / research use only. p-Hydroxybenzoic acid Beijing Lys Chemicals 4-Hydroxybenzoic acid BOC Sciences For experimental / research use only. 4-Hydroxybenzoic acid 98% Charkit Chemical HYDROXYBENZOIC ACID, P- POLYMER GRADE Charkit Chemical HYDROXYBENZOIC ACID,4- PURIFIED CLEAN ROOM EMD Millipore For experimental / research use only. 4-Hydroxybenzoic Acid sds ExtraSynthese For experimental / research use only. 4-Hydroxybenzoic acid (HPLC) ≥90% Parchem para-salicylic acid Penta International p-HYDROXYBENZOIC ACID Prodasynth PARA-HYDROXYBENZOIC ACID (> 99%) Santa Cruz Biotechnology For experimental / research use only. p-Salicylic Acid Sigma-Aldrich 4-Hydroxybenzoic acid, ≥99%, FG sds Certified Food Grade Products TCI AMERICA For experimental / research use only. 4-Hydroxybenzoic Acid >99.0%(GC)(T) sds   Safety Information: Preferred SDS: View European information : Most important hazard(s): Xn - Harmful. R 22 - Harmful if swallowed. R 36/38 - Irritating to skin and eyes. R 41 - Risk of serious damage to eyes. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 22 - Do not breath dust. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-mouse LD50 2200 mg/kg (Sokol, 1952) intraperitoneal-rat LD50 340 mg/kg BEHAVIORAL: MUSCLE WEAKNESS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 85, 1986. intraperitoneal-mouse LD50 210 mg/kg BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956. oral-mouse LD50 2200 mg/kg Drug Standards. Vol. 20, Pg. 89, 1952. oral-rat LD50 > 10000 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE WEAKNESS Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(7), Pg. 53, 1984. Dermal Toxicity: subcutaneous-mouse LD50 1050 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 128, Pg. 135, 1960. Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavoring agents Recommendation for para-salicylic acid usage levels up to:   not for fragrance use.   Maximised Survey-derived Daily Intakes (MSDI-EU): 16.00 (μg/capita/day) Maximised Survey-derived Daily Intakes (MSDI-USA): 17.00 (μg/capita/day) Structure Class: I Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 20 Click here to view publication 20   average usual ppm average maximum ppm baked goods: 60.00000 360.00000 beverages(nonalcoholic): 20.00000 100.00000 beverages(alcoholic): 50.00000 300.00000 breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: 30.00000 200.00000 fish products: - - frozen dairy: 50.00000 300.00000 fruit ices: 50.00000 300.00000 gelatins / puddings: - - granulated sugar: - - gravies: - - hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - - milk products: 50.00000 300.00000 nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: 50.00000 300.00000 soups: - - sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1] View page or View pdf Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf EPI System: View Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):99-96-7 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :135 National Institute of Allergy and Infectious Diseases:Data SCCNFP:opinion WGK Germany:1 4-hydroxybenzoic acid Chemidplus:0000099967 RTECS:DH1925000 for cas# 99-96-7   References:   4-hydroxybenzoic acid NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 99-96-7 Pubchem (cid): 135 Pubchem (sid): 134972218   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View Golm Metabolome Database: Search Metabolomics Database: Search UM BBD: Search KEGG (GenomeNet): C00156 HMDB (The Human Metabolome Database): HMDB00500 FooDB: FDB010508 YMDB (Yeast Metabolome Database): YMDB00495 Export Tariff Code: 2918.29.2200 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View   Potential Blenders and core components note None Found   Potential Uses:   preservatives   Occurrence (nature, food, other):note   apple fruit Search Trop Picture   arrowroot leaf Search Trop Picture   barley seed Search Trop Picture   bean black bean root Search Trop Picture   bean fava bean shoot Search Trop Picture   bean field bean root Search Trop Picture   beet root Search Trop Picture   bilberry fruit Search Trop Picture   bilberry fruit juice Search Trop Picture   bilberry leaf Search Trop Picture   blueberry plant Search Trop Picture   broccoli asparagus broccoli leaf Search Trop Picture   buckwheat testa Search Trop Picture   cacao bean Search Trop Picture   cantaloupe plant Search Trop Picture   cardamom leaf Search Trop Picture   carrot root Search Trop Picture   cashew leaf Search Trop Picture   cherry sour cherry plant Search Trop Picture   chicory leaf Search Trop Picture   coconut leaf Search Trop Picture   coffee Search PMC Picture   coriander fruit Search Trop Picture   coriander plant Search Trop Picture   coriander seed Search Trop Picture   corn tissue culture Search Trop Picture   currant red currant fruit Search Trop Picture   date palm stem Search Trop Picture   evening-primrose plant Search Trop Picture   fennel seed Search Trop Picture   flax sprout Search Trop Picture   garlic bulb Search Trop Picture   garlic plant Search Trop Picture   ginger plant Search Trop Picture   ginkgo biloba leaf Search Trop Picture   ginkgo biloba plant Search Trop Picture   grape Search Trop Picture   grape hull husk Search Trop Picture   grape leaf Search Trop Picture   grape root Search Trop Picture   horseradish root Search Trop Picture   oat seed Search Trop Picture   olive fruit Search Trop Picture   onion bulb Search Trop Picture   onion leaf Search Trop Picture   onion root Search Trop Picture   oregano leaf Search Trop Picture   oregano plant Search Trop Picture   pea root Search Trop Picture   pea seed Search Trop Picture   peanut seed Search Trop Picture   poppy opium poppy pericarp Search Trop Picture   raspberry red raspberry fruit juice Search Trop Picture   raspberry red raspberry juice Search Trop Picture   raspberry red raspberry plant Search Trop Picture   rice plant Search Trop Picture   rubus spectabilis leaf Search Trop Picture   sage Search Trop Picture   salmonberry leaf Search Trop Picture   soybean leaf Search Trop Picture   soybean root Search Trop Picture   soybean seed Search Trop Picture   sunflower seed Search Trop Picture   tarragon leaf Search Trop Picture   thyme plant Search Trop Picture   walnut black walnut nut Search Trop Picture   wheat seed Search Trop Picture   Synonyms:   benzoic acid, 4-hydroxy-   benzoic acid, p-hydroxy- 4- carboxyphenol p- carboxyphenol para- hydroxy benzoic acid 4- hydroxy-benzoic acid p- hydroxy-benzoic acid   hydroxybenzene carboxylic acid p- hydroxybenzoate para- hydroxybenzoate 4- hydroxybenzoic acid p- hydroxybenzoic acid para- hydroxybenzoic acid   hydroxybenzoic acid, para 4- hydroxybenzoicacid p- hydroxylbenzoic acid   paraben-acid 4- salicylic acid p- salicylic acid para- salicylic acid p- salicylicacid   Articles: J-Stage:Cellulase Applied to the Leaves of Sweet Pepper (Capsicum annuum L. var. grossum) Upregulates the Production of Salicylic and Azelaic Acids

Notes: Isol. from many plants, free and combined. Alkyl esters of 4-hydroxybenzoic acid (see below) are used as food and cosmetic preservatives, mainly in their Na salt form, which makes them more water soluble. They are active at low concentrations and more pH-independent than the commonly used Benzoic acid DVN38-Z and 2,4-Hexadienoic acid GMZ10-P. The taste is more detectable than for those preservatives. Effectiveness increases with chain length of the alcohol, but for some microorganisms this reduces cell permeability and thus counteracts the increased efficiency