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cyclohexyl formate
formic acid, cyclohexyl ester

Supplier Sponsors

Penta International Corporation

Chemistry innovation
At Penta, our products and services help businesses do business better.
For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
US Email:	Technical Services
US Email:	Sales
US Voice: (973) 740-2300
US Fax: (973) 740-1839
GSC100541102920 GSC100541102920
Product(s):
03-84500 CYCLOHEXYL FORMATE

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.
Synerzine is a leading supplier of flavor and fragrance ingredients.
Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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US Email:	Sales
US Voice: (404) 524-6744
US Fax: (404) 577-1651
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Products List:	View
GSC100541102920 GSC100541102920
Product(s):
W0318 Cyclohexyl Formate

Flavor Demo Formulas
Name:	cyclohexyl formate
CAS Number:	4351-54-6	3D/inchi
ECHA EINECS - REACH Pre-Reg:	224-415-3
FDA UNII:	ESO2F2836U
Nikkaji Web:	J100.653C
CoE Number:	498
XlogP:	1.80 (est)
Molecular Weight:	128.17104000
Formula:	C7 H12 O2
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:flavor and fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Flavoring:	1095 cyclohexyl formate
DG SANTE Food Flavourings:	09.160 cyclohexyl formate
FEMA Number:	2353 cyclohexyl formate
FDA:	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):	4351-54-6 ; CYCLOHEXYL FORMATE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants.

Physical Properties:

Appearance:	colorless clear liquid (est)
Assay:	97.00 to 100.00
Food Chemicals Codex Listed:	No
Specific Gravity:	1.05200 to 1.06000 @ 25.00 °C.
Pounds per Gallon - (est).:	8.754 to 8.820
Refractive Index:	1.43900 to 1.44500 @ 20.00 °C.
Boiling Point:	162.00 to 163.00 °C. @ 760.00 mm Hg
Boiling Point:	100.00 °C. @ 35.00 mm Hg
Vapor Pressure:	1.785000 mmHg @ 25.00 °C. (est)
Flash Point:	120.00 °F. TCC ( 48.89 °C. )
logP (o/w):	2.100
Soluble in:
	acetic acid
	alcohol
	formic acid
	water, 1518 mg/L @ 25 °C (est)
Insoluble in:
	water
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Organoleptic Properties:

Odor Type: ethereal

ethereal cooling sweet fruity banana cherry jammy

Odor Description:at 100.00 %. ethereal cooling sweet fruity banana cherry jam

ethereal cooling sweet fruity banana

Odor Description:Ethereal and cooling with sweet fruity banana nuances
Mosciano, Gerard P&F 15, No. 1, 19, (1990)

Flavor Type: green

cooling green fruity banana

Taste Description: at 30.00 ppm. Slightly cooling, green and fruity banana
Mosciano, Gerard P&F 15, No. 1, 19, (1990)

Odor and/or flavor descriptions from others (if found).

Bedoukian Research

CYCLOHEXYL FORMATE

Odor Description:ether cooling sweet fruity banana cherry jam

Taste Description:green fruity banana

Cosmetic Information:

None found

Suppliers:

Safety Information:

European information :
Most important hazard(s):
Xi - Irritant
R 38 - Irritating to skin. S 02 - Keep out of the reach of children. S 24 - Avoid contact with skin. S 36 - Wear suitable protective clothing.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for cyclohexyl formate usage levels up to:
	4.0000 % in the fragrance concentrate.

Maximised Survey-derived Daily Intakes (MSDI-EU):		0.012 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA):		0.20 (μg/capita/day)
Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		7.00000	10.00000
beverages(nonalcoholic):		-	11.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	2.80000
fruit ices:		-	2.80000
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	8.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 51, (FGE.51)[1] - Consideration of alicyclic ketones and secondary alcohols and related esters evaluated by JECFA (59th meeting) and structurally related to alicyclic ketones, secondary alcohols and related esters evaluated by EFSA in FGE.09 (2004) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 51, Revision 1 (FGE.51Rev1): Consideration of alicyclic ketones and secondary alcohols and related esters evaluated by the JECFA (59th meeting) structurally related to alicyclic ketones secondary alcohols and related esters in FGE.09Rev3 (2011)
View page or View pdf

Flavouring Group Evaluation 51, Revision 2 (FGE.51Rev2): Consideration of alicyclic ketones and secondary alcohols and related esters evaluated by JECFA (59th meeting) structurally related to alicyclic ketones secondary alcohols and related esters in FGE.09Rev6 (2015)
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):4351-54-6

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :20358

National Institute of Allergy and Infectious Diseases:Data

WISER:UN 1993

WGK Germany:2

cyclohexyl formate

Chemidplus:0004351546

References:

	cyclohexyl formate
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	4351-54-6
Pubchem (cid):	20358
Pubchem (sid):	135269464
Pherobase:	View

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	HMDB31351
FooDB:	FDB003416
Export Tariff Code:	2915.13.0000
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View