Articles:
Notes:
musk enhancer - aldehyde C-14 and musk gx.
waxy floral fruity accord:
0.05 - leerall
0.01 - aldehyde C-14
0.05 - aldehyde C18 10%
0.01 - musk gx
0.01 - raspberry ketone 10%
0.01 - aldehyde C-16 10%
rose accord:
0.01 - dihydromyrcenol
0.05 - benzyl propionate
0.05 - linalyl acetate
0.05 - phenethyl alcohol
0.01 - aldehyde C-14 10%
0.20 - amyl cinnamaldehyde
0.01 - ma/hy shiff
0.05 - naphthyl ethyl ether
0.01 - aldehyde C-16 10%
0.05 - geraniol
new car accord:
0.01 - dimethyl benzyl carbinyl acetate
0.01 - alpha-ionone
0.05 - heptyl cyclopentanone
0.01 - musk gx
0.05 - aldehyde C-14
0.01 - dihydroisojasmonate
| Fragrance Demo Formulas Flavor Demo Formulas | ||
| Name: | 5-heptyloxolan-2-one | |
| CAS Number: | 104-67-6 |  3D/inchi
|
| Other: | 57084-17-0 | |
| ECHA EINECS - REACH Pre-Reg: | 203-225-4 | |
| FDA UNII: | QB1T0AG2YL | |
| Nikkaji Web: | J1.182G | |
| Beilstein Number: | 0081943 | |
| MDL: | MFCD00005405 | |
| FEMA Number: | 3091 | |
| CoE Number: | 179 | |
| XlogP3: | 3.30 (est) | |
| Molecular Weight: | 184.27880000 | |
| Formula: | C11 H20 O2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | JECFA evaluated gamma-undecalactone (CASrn as in Register). Register CASrn refers to the racemate. ADI: 0-1.25 (JECFA, 1968). | |
Category: cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
| JECFA Food Flavoring: | 233 gamma-undecalactone |
| Flavis Number: | 10.002 (Old) |
| DG SANTE Food Flavourings: | 10.002 undecano-1,4-lactone |
| FEMA Number: | 3091 gamma-undecalactone |
| FDA Mainterm: | GAMMA-UNDECALACTONE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
Physical Properties:
| Appearance: | colorless to pale yellow clear oily liquid (est) |
| Assay: | 99.00 to 100.00 % |
| Halogens: | Chlorine free |
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.94200 to 0.94500 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 7.838 to 7.863 |
| Specific Gravity: | 0.94200 to 0.94800 @ 20.00 °C. |
| Pounds per Gallon - est.: | 7.848 to 7.898 |
| Refractive Index: | 1.44800 to 1.45300 @ 20.00 °C. |
| Boiling Point: | 164.00 to 166.00 °C. @ 13.00 mm Hg |
| Boiling Point: | 297.00 °C. @ 760.00 mm Hg |
| Acid Value: | 5.00 max. KOH/g |
| Vapor Pressure: | 0.003000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 200.00 °F. TCC ( 93.33 °C. ) |
| logP (o/w): | 2.961 (est) |
| Shelf Life: | 24.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| alkali | |
| benzyl alcohol | |
| benzyl benzoate | |
| dipropylene glycol | |
| ethyl alcohol, 1:2 in 70% alcohol | |
| ethyl alcohol, 4.5 vol. 60% alcohol | |
| fixed oils | |
| paraffin oil | |
| propylene glycol | |
| water, slightly | |
| water, 128.3 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| glycerin | |
| Stability: | |
| cream | |
| detergent powder | |
| hair spray | |
| lotion | |
| non-discoloring in most media | |
| powder | |
| soap | |
Organoleptic Properties:
| Odor Type: | fruity |
| Odor Strength: | medium |
| Odor Description: at 100.00 %. | fruity peach creamy fatty lactonic apricot ketonic coconut |
| Substantivity: | 338 hour(s) at 100.00 % |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
masking agents perfuming agents solvents |
Safety Information:
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet. | |
| Human Experience: | 2 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: | |
|
gavage-rat LD50 [sex: M,F] 18500 mg/kg (Jenner et al., 1964) oral-rat LD50 18500 mg/kg SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic, flavor and fragrance agents | ||
| Recommendation for gamma-undecalactone (aldehyde C-14 (so-called)) usage levels up to: | |||
| 10.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 1200.00 (μg/capita/day) | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 7.10000 | |
| beverages(nonalcoholic): | - | 4.40000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | 90.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 3.00000 | |
| fruit ices: | - | 3.00000 | |
| gelatins / puddings: | - | 7.50000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 11.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of lactones used as flavor ingredients.View pdf | |
| European Food Safety Athority(efsa): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| Env. Mutagen Info. Center: | Search |
| EPA Substance Registry Services (TSCA): | 104-67-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 7714 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| 5-heptyloxolan-2-one | |
| Chemidplus: | 0000104676 |
| RTECS: | YQ2485000 for cas# 104-67-6 |
References:
| Leffingwell: | Chirality or Article |
| 5-heptyloxolan-2-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 104-67-6 |
| Pubchem (cid): | 7714 |
| Pubchem (sid): | 134970660 |
| Flavornet: | 104-67-6 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2009 |
| (IUPAC): | Atomic Weights of the Elements 2009 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Everything Added to Food in the United States (EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C08571 |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB008394 |
| YMDB (Yeast Metabolome Database): | YMDB01799 |
| Export Tariff Code: | 2932.20.5050 |
| Haz-Map: | View |
| Household Products: | Search |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| acacia | FR | |
| aldehydic | FR | |
| apple | FR | |
| apple green apple | FR | |
| apple red apple | FR | |
| apricot | FR | |
| arpege | ||
| blue grass | FR | |
| blue mist | FR | |
| bluebell | FR | |
| blueberry | FR | |
| bouquet | FR | |
| bubble gum | FR | |
| butterscotch | FR | |
| cabochard | ||
| calyx | ||
| cedar | FR | |
| chamade | ||
| cherry | FR | |
| cherry blossom | FR | |
| chloe | ||
| citrus | FR | |
| coconut | FR | |
| coconut tropical coconut | FR | |
| country meadow | FR | |
| cream | FR | |
| cucumber | FR | |
| currant | FR | |
| date | FR | |
| diorella | ||
| femme | ||
| fetes | FR | |
| fig | FR | |
| floral | FR | |
| fracas | ||
| fruit | FR | |
| fruit juicy fruit | FR | |
| gardenia | FR | |
| gooseberry | FR | |
| grape | FR | |
| green | FR | |
| grenadine | FL | |
| habuba | FR | |
| herbal | FR | |
| hibiscus | FR | |
| jasmin | FR | |
| joy | ||
| kiwi | FR | |
| leather russian leather | FR | |
| lilac | FR | |
| lily | FR | |
| lily of the valley | FR | |
| linden flower | FR | |
| lotus | FR | |
| magnolia | FR | |
| mango | FR | |
| maple | FR | |
| melon | FR | |
| mitsouko | ||
| mulberry | FR | |
| my sin | ||
| nahema | ||
| neroli | FR | |
| nut | FL | |
| papaya | FR | |
| passion blossom | FR | |
| passion fruit | FR | |
| peach | FR | |
| peach blossom | FR | |
| pear | FR | |
| pina colada | FR | |
| pistachio | FL | |
| plum | FR | |
| poison | ||
| powder | FR | |
| raspberry | FR | |
| rose | FR | |
| sea breeze | FR | |
| shalimar | ||
| spice | FR | |
| strawberry | FR | |
| tabu | ||
| tide | ||
| tropical | FL | |
| valerian | FL/FR | |
| vanilla | FR | |
| violet | FR | |
| wintergreen | FR | |
| woody | FR |
Occurrence (nature, food, other): note
| apple juice Search PMC Picture | |
| apricot fruit Search Trop Picture | |
| butter Search PMC Picture | |
| meat Search PMC Picture | |
| milk products Search PMC Picture | |
| osmanthus absolute @ trace% Data GC Search Trop Picture | |
| passion fruit Search Trop Picture | |
| peach fruit Search Trop Picture | |
| plum fruit Search Trop Picture | |
| plumcot fruit Search PMC Picture |
Synonyms:
| abriceine | |
| aldehyde (C-14) | |
| aldehyde C-14 | |
| aldehyde C-14 (gamma-undecalactone) | |
| aldehyde C-14 (gamma-undecalactone) natural | |
| aldehyde C-14 (so-called) | |
| aldehyde C-14 extra | |
| aldehyde C-14 FCC | |
| aldehyde C-14 natural | |
| aldehyde C-14 natural (undecalactone gamma) | |
| aldehyde C-14, natural | |
| aldehyde C14 | |
| aldehyde C14 so-called | |
| C-14 aldehyde | |
| dihydro-5-heptyl-2(3H)-furanone | |
| 2(3H)- | furanone, 5-heptyldihydro- |
| 1,4- | hendecanolide |
| hendecylene methyl lactone | |
| 4- | heptyl butan-4-olide |
| gamma- | heptyl butyrolactone |
| gamma-N- | heptyl butyrolactone |
| 5- | heptyl dihydro-2(3H)-furanone |
| 4- | heptyl-4-hydroxybutanoic acid lactone |
| 4-N- | heptyl-4-hydroxybutanoic acid lactone |
| gamma- | heptyl-gamma-butyrolactone |
| 4- | heptylbutan-4-olide |
| 5- | heptyldihydro-2(3H)-furanone |
| 5- | heptyldihydrofuran-2(3H)-one |
| 5- | heptyloxolan-2-one |
| 4- | hydroxyundecanoic acid gamma-lactone |
| 4- | hydroxyundecanoic acid lactone |
| peach aldehyde | |
| peach lactone | |
| peach pure | |
| peche pure | |
| gamma- | undecalactone (aldehyde C-14 (so-called)) |
| gamma- | undecalactone (aldehyde C-14) |
| gamma | undecalactone (aldehyde C-14) (peach aldehyde) |
| gamma- | undecalactone (C-14) |
| nat.gamma- | undecalactone (C-14) |
| gamma- | undecalactone (natural) |
| gamma- | undecalactone (racemic) natural |
| gamma- | undecalactone chiral eec natural |
| gamma- | undecalactone FCC |
| gamma- | undecalactone natural |
| gamma- | undecalactone, ex 10-undecenoic acid |
| gamma- | undecalactone, nature-identical |
| undecan-4-olide | |
| undecano-1,4-lactone | |
| gamma- | undecanolactone |
| 1,4- | undecanolide |
| 4- | undecanolide |
| gamma- | undecanolide |
| gamma- | undecyl lactone |