EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

isomaltulose
6-O-alpha-D-glucopyranosyl-D-fructose

Supplier Sponsors

Name:(3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one
CAS Number: 13718-94-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:237-282-1
FDA UNII: V59P50X4UY
Nikkaji Web:J16.052K
Beilstein Number:0093820
MDL:MFCD00076094
XlogP3-AA:-4.80 (est)
Molecular Weight:342.29854000
Formula:C12 H22 O11
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:sweeteners, flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 184 Isomaltulose View - notice PDF
GRN 681 Dried isomaltulose syrup View - notice PDF
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 784.00 to 785.00 °C. @ 760.00 mm Hg (est)
Flash Point: 559.00 °F. TCC ( 292.50 °C. ) (est)
logP (o/w): -2.941 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Flavor Type: sweet
sweet
Taste Description: sweet
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Anhui Haibei
isoMaltulose
BOC Sciences
For experimental / research use only.
isomaltulose
Carbosynth
For experimental / research use only.
isoMaltulose
Glentham Life Sciences
Palatinose
Indis NV
For experimental / research use only.
Palatinose
Jiangyin Healthway
Isomaltulose
New functional food ingredients
O'Laughlin Industries
ISOMALTULOSE
Santa Cruz Biotechnology
For experimental / research use only.
Palatinose ≥99%
United International
Isomaltulose
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
sweeteners, flavor enhancers
Recommendation for isomaltulose usage levels up to:
 not for fragrance use.
 
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety evaluation of the food enzyme preparation isomaltulose synthase from Serratia plymuthica strain Z12A
View page or View pdf

Isomaltulose and normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :83686
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one
Chemidplus:0013718940
 
References:
 (3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):83686
Pubchem (sid):135041561
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2940.00.6000
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
For Odor
alcoholic
fusel oil
FL/FR
animal
methyl (E)-2-octenoate
FL/FR
anise
star
anise seed oil terpeneless
FL/FR
anisic
para-
acetanisole
FL/FR
ethyl para-anisate
FL/FR
balsamic
benzyl salicylate
FL/FR
ethyl cinnamate
FL/FR
dextro-
fenchone
FL/FR
guaiacyl phenyl acetate
FL/FR
hexyl benzoate
FL/FR
bready
furfural
FL/FR
buttery
acetoin
FL/FR
caramellic
caramel furanone solution
FL/FR
caramel pentadione
FL/FR
coffee dione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
ethyl cyclopentenolone
FL/FR
ethyl furaneol
FL/FR
ethyl maltol
FL/FR
levulinic acid
FL/FR
maltol
FL/FR
maltyl isobutyrate
FL/FR
maltyl propionate
FL/FR
maple furanone
FL/FR
5-
methyl furfural
FL/FR
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
strawberry furanone solution
FL/FR
cheesy
iso
valeric acid
FL/FR
chemical
iso
butyl formate
FL/FR
propyl propionate
FL/FR
chocolate
iso
amyl phenyl acetate
FL/FR
cocoa pentenal
FL/FR
citrus
2-
ethyl-1-hexanol
FL/FR
lime essence oil
FL/FR
dextro-
limonene
FL/FR
alpha-
terpinyl methyl ether
FL/FR
coconut
delta-
octalactone
FL/FR
creamy
3-
heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR
para-
vanillic acid
FL/FR
para-
vanillyl alcohol
FL/FR
veratraldehyde
FL/FR
dry
3,4-
xylenol
FL/FR
earthy
methyl 3-hexenoate
FL/FR
ethereal
ethyl acetate
FL/FR
ethyl formate
FL/FR
ethyl pyruvate
FL/FR
iso
propyl formate
FL/FR
fatty
(E)-2-
octenal
FL/FR
(E,Z,Z)-2,4,7-
tridecatrienal
FL/FR
floral
acetophenone
FL/FR
benzyl acetate
FL/FR
benzyl isobutyrate
FL/FR
citronellyl anthranilate
FL/FR
citronellyl phenyl acetate
FL/FR
ethyl phenyl acetate
FL/FR
geranyl isobutyrate
FL/FR
heliotropyl acetone
FL/FR
(Z)-3-
hexen-1-yl salicylate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hexyl lactate
FL/FR
hydroxycitronellal
FL/FR
hydroxycitronellol
FL/FR
alpha-
ionol
FL/FR
para-
methyl acetophenone
FL/FR
beta-
naphthyl methyl ketone
FL/FR
nonanol
FL/FR
phenethyl alcohol
FL/FR
phenethyl propionate
FL/FR
4-
phenyl-3-buten-2-ol
FL/FR
iso
propyl phenyl acetate
FL/FR
rhodinyl phenyl acetate
FL/FR
rose butanoate
FL/FR
rose oil (rosa damascena) russia
FL/FR
rose oil (rosa damascena) turkey
FL/FR
terpinyl valerate
FL/FR
tuberose absolute (from pommade)
FL/FR
fruity
allyl hexanoate
FL/FR
iso
butyl 2-butenoate
FL/FR
iso
butyl acetoacetate
FL/FR
iso
butyl anthranilate
FL/FR
iso
butyl butyrate
FL/FR
butyl butyrate
FL/FR
iso
butyl isovalerate
FL/FR
butyl isovalerate
FL/FR
ethyl 3-(2-furyl) propanoate
FL/FR
ethyl 3-hexenoate
FL/FR
ethyl 3-hydroxyhexanoate
FL/FR
ethyl benzoyl acetate
FL/FR
ethyl butyrate
FL/FR
ethyl isovalerate
FL/FR
ethyl lactate
FL/FR
ethyl methyl-para-tolyl glycidate
FL/FR
ethyl propionate
FL/FR
(E,E)-
ethyl sorbate
FL/FR
ethyl valerate
FL/FR
2-
hexen-1-ol
FL/FR
hexyl acetate
FL/FR
linalyl isobutyrate
FL/FR
menthyl isovalerate
FL/FR
methyl 3-nonenoate
FL/FR
methyl anthranilate
FL/FR
2-
methyl butyl acetate
FL/FR
methyl heptanoate
FL/FR
methyl isobutyrate
FL/FR
methyl valerate
FL/FR
neryl isobutyrate
FL/FR
octyl butyrate
FL/FR
octyl propionate
FL/FR
2-
pentanone
FL/FR
pineapple hydroxyhexanoate
FL/FR
prenyl acetate
FL/FR
iso
propyl 2-methyl butyrate
FL/FR
propyl butyrate
FL/FR
iso
propyl butyrate
FL/FR
propyl heptanoate
FL/FR
propyl hexanoate
FL/FR
propyl isobutyrate
FL/FR
iso
propyl octanoate
FL/FR
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
strawberry glycidate 2
FL/FR
tetrahydrofurfuryl acetate
FL/FR
para-
tolualdehyde
FL/FR
tolualdehydes (mixed o,m,p)
FL/FR
tropical ionone
FL/FR
vanilla carboxylate
FL/FR
green
cucumber essence
FL/FR
(Z)-4-
hepten-1-ol
FL/FR
hexyl isobutyrate
FL/FR
hexyl phenyl acetate
FL/FR
(E,Z)-3,6-
nonadien-1-yl acetate
FL/FR
(E)-2-
octen-1-ol
FL/FR
2-
octen-1-ol
FL/FR
phenethyl tiglate
FL/FR
terpinyl propionate
FL/FR
herbal
anethum graveolens herb tincture
FL/FR
clary sage absolute
FL/FR
linalyl isovalerate
FL/FR
linalyl octanoate
FL/FR
lovage tincture
FL/FR
perillaldehyde
FL/FR
3-
propylidene phthalide
FL/FR
honey
methyl phenyl acetate
FL/FR
propyl phenyl acetate
FL/FR
licorice
(E)-
anethol
FL/FR
medicinal
2,6-
xylenol
FL/FR
minty
ethyl benzoate
FL/FR
ethyl salicylate
FL/FR
methyl salicylate
FL/FR
peppermint oil america
FL/FR
peppermint oil idaho
FL/FR
musk
ethylene brassylate
FL/FR
musty
ketoiso
phorone
FL/FR
spicy
iso
butyl angelate
FL/FR
4-
ethyl guaiacol
FL/FR
iso
eugenol
FL/FR
eugenol
FL/FR
iso
eugenyl acetate
FL/FR
iso
eugenyl phenyl acetate
FL/FR
para-
methoxycinnamaldehyde
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
methyl heptadienone
FL/FR
alpha-
methyl-(E)-cinnamaldehyde
FL/FR
(E)-
propyl 2-furan acrylate
FL/FR
(E)-
tiglic acid
FL/FR
sweet
vanilla bean absolute (vanilla spp.)
FL/FR
vanilla oleoresin bali
FL/FR
vanilla resinoid
FL/FR
vanilla tahitensis fruit extract
FL/FR
tonka
mint lactone
FL/FR
octahydrocoumarin
FL/FR
tropical
genet absolute
FL/FR
vanilla
ethyl vanillin
FL/FR
ethyl vanillin propylene glycol acetal
FL/FR
propenyl guaethol
FL/FR
vanilla aromatica fruit extract
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanilla oleoresin bourbon
FL/FR
vanillin
FL/FR
vanillin propylene glycol acetal
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
vanillylidene acetone
FL/FR
waxy
ethyl decanoate
FL/FR
ethyl myristate
FL/FR
ethyl octanoate
FL/FR
nonanoic acid
FL/FR
1-
undecanol
FL/FR
woody
2-
methoxy-4-vinyl phenol
FL/FR
For Flavor
acidic
(E)-2-
hexenoic acid
FL
levulinic acid
FL/FR
aldehydic
1-
undecanol
FL/FR
anise
(E)-
anethol
FL/FR
star
anise seed oil terpeneless
FL/FR
ethyl para-anisate
FL/FR
anisic
para-
acetanisole
FL/FR
balsamic
benzyl salicylate
FL/FR
ethyl cinnamate
FL/FR
vanillylidene acetone
FL/FR
berry
heliotropyl acetone
FL/FR
bitter
(E,Z,Z)-2,4,7-
tridecatrienal
FL/FR
brown
furfural
FL/FR
5-
methyl furfural
FL/FR
tetrahydrofurfuryl acetate
FL/FR
(E)-
tiglic acid
FL/FR
burnt
furfuryl alcohol
FL
2,6-
xylenol
FL/FR
caramellic
caramel dione
FL
caramel furanone
FL
caramel furanone solution
FL/FR
caramel pentadione
FL/FR
cyclotene
FL/FR
cyclotene hydrate
FL/FR
ethyl furaneol
FL/FR
ethyl maltol
FL/FR
lucuma flavor
FL
maltol
FL/FR
maltyl propionate
FL/FR
maple distillates
FL
maple furanone
FL/FR
3-
methyl butyl 2-furyl butyrate
FL
pyruvaldehyde
FL
shoyu furanone
FL/FR
strawberry furanone
FL/FR
strawberry furanone acetate
FL/FR
strawberry furanone solution
FL/FR
cheesy
ammonium isovalerate 30% in pg
FL
iso
valeric acid
FL/FR
cherry
para-
methoxycinnamaldehyde
FL/FR
chocolate
bittersweet
chocolate flavor
FL
citrus
lime essence oil
FL/FR
dextro-
limonene
FL/FR
ketoiso
phorone
FL/FR
coconut
massoia bark oil CO2 extract
FL
octahydrocoumarin
FL/FR
delta-
octalactone
FL/FR
coffee
coffee dione
FL/FR
cooling
dextro-
fenchone
FL/FR
peppermint oil america
FL/FR
creamy
acetoin
FL/FR
divanillin
FL
para-
methyl acetophenone
FL/FR
mint lactone
FL/FR
para-
vanillic acid
FL/FR
para-
vanillyl alcohol
FL/FR
veratraldehyde
FL/FR
estery
octyl propionate
FL/FR
ethereal
ethyl acetate
FL/FR
ethyl formate
FL/FR
methyl isobutyrate
FL/FR
fatty
2-
ethyl-1-hexanol
FL/FR
nonanoic acid
FL/FR
(E)-2-
octen-1-ol
FL/FR
2-
octen-1-ol
FL/FR
(E)-2-
octenal
FL/FR
floral
2-
acetyl-5-methyl thiophene
FL
iso
amyl phenyl acetate
FL/FR
citronellyl phenyl acetate
FL/FR
cocoa pentenal
FL/FR
geranyl isobutyrate
FL/FR
linalyl isobutyrate
FL/FR
methyl phenyl acetate
FL/FR
beta-
naphthyl methyl ketone
FL/FR
phenethyl alcohol
FL/FR
phenethyl propionate
FL/FR
rose oil (rosa damascena) russia
FL/FR
rose oil (rosa damascena) turkey
FL/FR
tropical ionone
FL/FR
tuberose absolute (from pommade)
FL/FR
fruity
allyl hexanoate
FL/FR
benzyl acetate
FL/FR
benzyl isobutyrate
FL/FR
iso
butyl acetoacetate
FL/FR
iso
butyl anthranilate
FL/FR
iso
butyl butyrate
FL/FR
butyl butyrate
FL/FR
butyl isovalerate
FL/FR
citronellyl anthranilate
FL/FR
(E)-2-
decenoic acid
FL
ethyl 3-(2-furyl) propanoate
FL/FR
ethyl 3-hexenoate
FL/FR
ethyl 3-hydroxyhexanoate
FL/FR
ethyl 3-oxohexanoate
FL
ethyl benzoyl acetate
FL/FR
ethyl butyrate
FL/FR
ethyl isovalerate
FL/FR
ethyl lactate
FL/FR
ethyl methyl-para-tolyl glycidate
FL/FR
ethyl propionate
FL/FR
(E,E)-
ethyl sorbate
FL/FR
ethyl valerate
FL/FR
furfuryl valerate
FL
2-
furyl pentyl ketone
FL
fusel oil
FL/FR
3-
heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR
2-
hexen-1-ol
FL/FR
hexyl acetate
FL/FR
hexyl lactate
FL/FR
hexyl phenyl acetate
FL/FR
linalyl isovalerate
FL/FR
linalyl octanoate
FL/FR
menthyl isovalerate
FL/FR
methyl (E)-2-octenoate
FL/FR
methyl (E)-3-nonenoate
FL
methyl 3-hexenoate
FL/FR
methyl 3-nonenoate
FL/FR
methyl anthranilate
FL/FR
2-
methyl butyl acetate
FL/FR
methyl heptanoate
FL/FR
(E,E)-
methyl sorbate
FL
methyl valerate
FL/FR
neryl isobutyrate
FL/FR
2-
pentanone
FL/FR
pineapple hydroxyhexanoate
FL/FR
prenyl acetate
FL/FR
(E)-
propyl 2-furan acrylate
FL/FR
iso
propyl 2-methyl butyrate
FL/FR
propyl butyrate
FL/FR
iso
propyl butyrate
FL/FR
iso
propyl formate
FL/FR
propyl hexanoate
FL/FR
propyl isobutyrate
FL/FR
iso
propyl octanoate
FL/FR
rose butanoate
FL/FR
strawberry glycidate 1 (aldehyde C-16 (so-called))
FL/FR
strawberry glycidate 2
FL/FR
terpinyl valerate
FL/FR
tolualdehydes (mixed o,m,p)
FL/FR
vanilla carboxylate
FL/FR
green
anethum graveolens herb tincture
FL/FR
iso
butyl 2-butenoate
FL/FR
iso
butyl angelate
FL/FR
iso
butyl isovalerate
FL/FR
cucumber essence
FL/FR
2-
ethyl butyraldehyde
FL
(Z)-4-
hepten-1-ol
FL/FR
(E)-2-
heptenal
FL
(Z)-3-
hexen-1-yl salicylate
FL/FR
hexyl benzoate
FL/FR
hexyl isobutyrate
FL/FR
methyl heptadienone
FL/FR
(E,Z)-3,6-
nonadien-1-yl acetate
FL/FR
phenethyl tiglate
FL/FR
3-
propylidene phthalide
FL/FR
terpinyl propionate
FL/FR
hay
genet absolute
FL/FR
herbal
clary sage absolute
FL/FR
lovage tincture
FL/FR
honey
ethyl phenyl acetate
FL/FR
dehydrated and ground
honey
FL
honey flavor
FL
iso
propyl phenyl acetate
FL/FR
propyl phenyl acetate
FL/FR
jammy
ethyl cyclopentenolone
FL/FR
maltyl isobutyrate
FL/FR
medicinal
ethyl benzoate
FL/FR
minty
ethyl salicylate
FL/FR
methyl salicylate
FL/FR
peppermint oil idaho
FL/FR
molasses
molasses blackstrap
FL
mushroom
methional diethyl acetal
FL
musk
ethylene brassylate
FL/FR
phenolic
guaiacyl phenyl acetate
FL/FR
potato
sweet
potato flavor
FL
powdery
acetophenone
FL/FR
hydroxycitronellol
FL/FR
praline
praline flavor
FL
rummy
iso
butyl formate
FL/FR
ethyl pyruvate
FL/FR
salty
1-(2-
hydroxy-4-methoxyphenyl)-3-(pyridin-2-yl)propan-1-one
FL
smoky
2-
methoxy-4-vinyl phenol
FL/FR
3,4-
xylenol
FL/FR
spicy
iso
eugenol
FL/FR
eugenol
FL/FR
iso
eugenyl acetate
FL/FR
iso
eugenyl phenyl acetate
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
alpha-
methyl-(E)-cinnamaldehyde
FL/FR
perillaldehyde
FL/FR
para-
tolualdehyde
FL/FR
sulfurous
S-
ethyl thioacetate
FL
sweet
acesulfame potassium
FL
acetone alcohol
FL
advantame
FL
agave flavor
FL
alitame anhydrous
FL
aspartame
FL
aspartame-acesulfame salt
FL
corn syrup high fructose
FL
corn syrups
FL
dextrose monohydrate
FL
3',7-
dihydroxy-4'-methoxyflavan
FL
ethyl 3-(2-hydroxyphenyl) propionate
FL
glucosyl steviol glycosides
FL
glycyrrhizic acid
FL
honey enhancer
FL
levulose
FL
luo han fruit concentrate
FL
maltitol
FL
maltose
FL
molasses
FL
molasses concentrate
FL
molasses distillates
FL
molasses flavor
FL
laevo-
ornithine hydrochloride
FL
rebaudioside C
FL
rebaudioside C 30%
FL
glucosylated
rubus suavissimus extract, 60% glucosylated rubusoside glycosides
FL
sodium 2-(4-methoxyphenoxy) propionate
FL
dextro-
sorbitol
FL
stevia rebaudiana extract, rebaudioside A 22%
FL
stevia rebaudiana extract, rebaudioside A 60%
FL
stevia rebaudiana extract, rebaudioside A 80%
FL
steviol
FL
steviol glycoside extract, rebaudioside C 22%
FL
enzyme modified
steviol glycosides
FL
stevioside
FL
sucralose
FL
maple
sugar
FL
sugar
FL
sugar cane distillate
FL
sugar extenders
FL
burnt
sugar flavor
FL
sugar flavor
FL
brown
sugar flavor
FL
sugar replacers
FL
sweet & sour candy flavor
FL
sweet flavor
FL
thaumatin b-recombinant
FL
vanilla bean absolute (vanilla spp.)
FL/FR
vanilla concentrate
FL
vanilla oleoresin bali
FL/FR
vanilla resinoid
FL/FR
vanilla tahitensis fruit extract
FL/FR
dextro,laevo-
xylose
FL
tropical
propyl propionate
FL/FR
vanilla
ethyl vanillin
FL/FR
ethyl vanillin propylene glycol acetal
FL/FR
propenyl guaethol
FL/FR
vanilla aromatica fruit extract
FL/FR
vanilla bean absolute (vanilla planifolia)
FL/FR
vanilla oleoresin bourbon
FL/FR
vanillin
FL/FR
vanillin propylene glycol acetal
FL/FR
vanillyl acetate
FL/FR
vanillyl isobutyrate
FL/FR
vegetable
tyramine
FL
waxy
ethyl decanoate
FL/FR
ethyl myristate
FL/FR
ethyl octanoate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
hydroxycitronellal
FL/FR
nonanol
FL/FR
octyl butyrate
FL/FR
4-
phenyl-3-buten-2-ol
FL/FR
propyl heptanoate
FL/FR
rhodinyl phenyl acetate
FL/FR
woody
4-
ethyl guaiacol
FL/FR
alpha-
ionol
FL/FR
alpha-
terpinyl methyl ether
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
6-O-alpha-D-glucopyranosyl-D-fructose
6-O-alpha-dextro-glucopyranosyl-dextro-fructose
 palatinose
(3S,4R,5R)-1,3,4,5-tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one
 

Articles:

PubMed:Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice.
PubMed:The effect of using isomaltulose (Palatinose™) to modulate the glycaemic properties of breakfast on the cognitive performance of children.
PubMed:Synthesis and characterization of isomaltulose-derived oligosaccharides produced by transglucosylation reaction of Leuconostoc mesenteroides dextransucrase.
PubMed:Development of synbiotics with inulin, palatinose, alpha-cyclodextrin and probiotic bacteria.
PubMed:Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial.
PubMed:Transglycosylations employing recombinant α- and β-galactosidases and novel donor substrates.
PubMed:Current studies on sucrose isomerase and biological isomaltulose production using sucrose isomerase.
PubMed:Crystallization and preliminary X-ray crystallographic analysis of α-glucosidase HaG from Halomonas sp. strain H11.
PubMed:Functional characterization of the sucrose isomerase responsible for trehalulose production in plant-associated Pectobacterium species.
PubMed:The structural basis of Erwinia rhapontici isomaltulose synthase.
PubMed:The effect of lactose-isomaltulose-containing growing-up milks on cognitive performance of Indonesian children: a cross-over study.
PubMed:Is there a specific role for sucrose in sports and exercise performance?
PubMed:Simple, fast, and efficient process for producing and purifying trehalulose.
PubMed:Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity.
PubMed:Potential applications of carbohydrases immobilization in the food industry.
PubMed:Enhancing isomaltulose production by recombinant Escherichia coli producing sucrose isomerase: culture medium optimization containing agricultural wastes and cell immobilization.
PubMed:Mature-stem expression of a silencing-resistant sucrose isomerase gene drives isomaltulose accumulation to high levels in sugarcane.
PubMed:Influence of processing on the volatile profile of strawberry spreads made with isomaltulose.
PubMed:The effect of selected synbiotics on microbial composition and short-chain fatty acid production in a model system of the human colon.
PubMed:Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM.
PubMed:Combining protein and carbohydrate increases postprandial insulin levels but does not improve glucose response in patients with type 2 diabetes.
PubMed:Insight into the role of sugars in bud burst under light in the rose.
PubMed:Metabolic effects of replacing sucrose by isomaltulose in subjects with type 2 diabetes: a randomized double-blind trial.
PubMed:Immobilization of glucosyltransferase from Erwinia sp. using two different techniques.
PubMed:Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion.
PubMed:Reduced glycaemic and insulinaemic responses following trehalose and isomaltulose ingestion: implications for postprandial substrate use in impaired glucose-tolerant subjects.
PubMed:Microbial sucrose isomerases: producing organisms, genes and enzymes.
PubMed:Mechanism-oriented redesign of an isomaltulose synthase to an isomelezitose synthase by site-directed mutagenesis.
PubMed:Exercise dose and insulin sensitivity: relevance for diabetes prevention.
PubMed:Isomaltulose improves glycemia and maintains run performance in type 1 diabetes.
PubMed:Isomaltulose is actively metabolized in plant cells.
PubMed:The effect of high lactose-isomaltulose on cognitive performance of young children. A double blind cross-over design study.
PubMed:Field performance of transgenic sugarcane expressing isomaltulose synthase.
PubMed:Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB-1 on Saccharomyces cerevisiae.
PubMed:Immobilization of Erwinia sp. D12 Cells in Alginate-Gelatin Matrix and Conversion of Sucrose into Isomaltulose Using Response Surface Methodology.
PubMed:Sucrose isomerase and its mutants from Erwinia rhapontici can synthesise α-arbutin.
PubMed:GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats.
PubMed:A new immune-modulating diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose attenuates gut ischemia-reperfusion injury in mice.
PubMed:A combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus.
PubMed:Studies on absorption and metabolism of palatinose (isomaltulose) in rats.
PubMed:Microbial production of palatinose through extracellular expression of a sucrose isomerase from Enterobacter sp. FMB-1 in Lactococcus lactis MG1363.
PubMed:Cloning and characterization of a sucrose isomerase from Erwinia rhapontici NX-5 for isomaltulose hyperproduction.
PubMed:Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM.
PubMed:Transgenic expression of trehalulose synthase results in high concentrations of the sucrose isomer trehalulose in mature stems of field-grown sugarcane.
PubMed:Palatinose-blended sugar compared with sucrose: different effects on insulin sensitivity after 12 weeks supplementation in sedentary adults.
PubMed:Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose).
PubMed:Manipulation of glycemic response with isomaltulose in a milk-based drink does not affect cognitive performance in healthy adults.
PubMed:Effect of concentration and substrate flow rate on isomaltulose production from sucrose by Erwinia sp. cells immobilized in calcium-alginate using packed bed reactor.
PubMed:Sucrose: A prospering and sustainable organic raw material.
PubMed:Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45.
PubMed:Safer glycemic control using isomaltulose-based enteral formula: a pilot randomized crossover trial.
PubMed:Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use.
PubMed:Glucosylation of raffinose via alternansucrase acceptor reactions.
PubMed:Molecular cloning and functional characterization of a sucrose isomerase (isomaltulose synthase) gene from Enterobacter sp. FMB-1.
PubMed:Slowly digestible carbohydrate sources can be used to attenuate the postprandial glycemic response to the ingestion of diabetes-specific enteral formulas.
PubMed:Structural determinants of product specificity of sucrose isomerases.
PubMed:Isomaltulose production from sucrose by Protaminobacter rubrum immobilized in calcium alginate.
PubMed:Beneficial effects on glucose metabolism of chronic feeding of isomaltulose versus sucrose in rats.
PubMed:Isomalt production by cloning, purifying and expressing of the MDH gene from Pseudomonas fluorescens DSM 50106 in different strains of E. coli.
PubMed:[Physiological and biochemical properties of the bacterium Erwinia rhapontici, a producer of isomaltulose synthase].
PubMed:Palatinose and oleic acid act together to prevent pancreatic islet disruption in nondiabetic obese Zucker rats.
PubMed:Food labeling: health claims; dietary noncariogenic carbohydrate sweeteners and dental caries. Final rule.
PubMed:Inhibitory action of palatinose and its hydrogenated derivatives on the hydrolysis of alpha-glucosylsaccharides in the small intestine.
PubMed:Isomaltose production by modification of the fructose-binding site on the basis of the predicted structure of sucrose isomerase from "Protaminobacter rubrum".
PubMed:Recent progress in the synthesis of carbohydrate-based amphiphilic materials: the examples of sucrose and isomaltulose.
PubMed:Molecular and physiological role of the trehalose-hydrolyzing alpha-glucosidase from Thermus thermophilus HB27.
PubMed:Role of periplasmic trehalase in uptake of trehalose by the thermophilic bacterium Rhodothermus marinus.
PubMed:[Production of fructooligosaccharide syrup from sucrose in combination with palatinose and trehalose].
PubMed:Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats.
PubMed:Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization.
PubMed:A palatinose-based balanced formula improves glucose tolerance, serum free fatty acid levels and body fat composition.
PubMed:Inhibitory effect of palatinose on glucose absorption in everted rat gut.
PubMed:Exogenous oxidation of isomaltulose is lower than that of sucrose during exercise in men.
PubMed:A new colorimetric method for determining the isomerization activity of sucrose isomerase.
PubMed:Effects of a novel palatinose based enteral formula (MHN-01) carbohydrate-adjusted fluid diet in improving the metabolism of carbohydrates and lipids in patients with esophageal cancer complicated by diabetes mellitus.
PubMed:Doubled sugar content in sugarcane plants modified to produce a sucrose isomer.
PubMed:Isomaltulose production using free cells: optimisation of a culture medium containing agricultural wastes and conversion in repeated-batch processes.
PubMed:Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men.
PubMed:Conversion of sucrose into isomaltulose by Enterobacter sp. FMB1, an isomaltulose-producing microorganism isolated from traditional Korean food.
PubMed:Application of response surface methodology to cell immobilization for the production of palatinose.
PubMed:Sucrose substitutes and their role in caries prevention.
PubMed:Molecular characterization of the alpha-glucosidase activity in Enterobacter sakazakii reveals the presence of a putative gene cluster for palatinose metabolism.
PubMed:Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA.
PubMed:Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45.
PubMed:Characterization of the highly efficient sucrose isomerase from Pantoea dispersa UQ68J and cloning of the sucrose isomerase gene.
PubMed:The high-affinity maltose/trehalose ABC transporter in the extremely thermophilic bacterium Thermus thermophilus HB27 also recognizes sucrose and palatinose.
PubMed:Klebsiella singaporensis sp. nov., a novel isomaltulose-producing bacterium.
PubMed:Comparative effect of repeated ingestion of difructose anhydride III and palatinose on the induction of gastrointestinal symptoms in humans.
PubMed:Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion.
PubMed:Characterization of Pantoea dispersa UQ68J: producer of a highly efficient sucrose isomerase for isomaltulose biosynthesis.
PubMed:Fermentation of five sucrose isomers by human dental plaque bacteria.
PubMed:Enhanced conversion of sucrose to isomaltulose by a mutant of Erwinia rhapontici.
PubMed:Production of palatinose using Serratia plymuthica cells immobilized in chitosan.
PubMed:The effect of palatinose on mental concentration in humans.
PubMed:Straightforward route for anchoring a glucosyl moiety onto nucleophilic species: reaction of amines and alcohols with carboxymethyl 3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 2-O-lactone.
PubMed:Substrate induction of isomaltulose synthase in a newly isolated Klebsiella sp. LX3.
PubMed:Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism.
PubMed:Distinct sucrose isomerases catalyze trehalulose synthesis in whiteflies, Bemisia argentifolii, and Erwinia rhapontici.
PubMed:Structural and functional analysis of a putative gene cluster for palatinose transport on the linear chromosome of Agrobacterium tumefaciens MAFF301001.
PubMed:Sugar-regulated expression of a putative hexose transport gene in grape.
PubMed:A motif rich in charged residues determines product specificity in isomaltulose synthase.
PubMed:Decreased sucrose content triggers starch breakdown and respiration in stored potato tubers (Solanum tuberosum).
PubMed:Expression, crystallization and preliminary X-ray analysis of isomaltulose synthase (PalI) from Klebsiella sp. LX3.
PubMed:Glycosidation of fructose-containing disaccharides using MCM-41 material as the catalyst.
PubMed:13-Week oral toxicity study with isomaltulose (Palatinose) in rats.
PubMed:Isomaltulose (Palatinose): a review of biological and toxicological studies.
PubMed:Potato tubers as bioreactors for palatinose production.
PubMed:Isomaltulose synthase from Klebsiella sp. strain LX3: gene cloning and characterization and engineering of thermostability.
PubMed:Metabolizable and non-metabolizable sugars activate different signal transduction pathways in tomato.
PubMed:High-level production of the non-cariogenic sucrose isomer palatinose in transgenic tobacco plants strongly impairs development.
PubMed:Phosphorylation and metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae.
PubMed:The sucrose analog palatinose leads to a stimulation of sucrose degradation and starch synthesis when supplied to discs of growing potato tubers.
PubMed:Responses of the ant Lasius niger to various compounds perceived as sweet in humans: a structure-activity relationship study.
PubMed:Cloning and characterization of the gene cluster for palatinose metabolism from the phytopathogenic bacterium Erwinia rhapontici.
PubMed:Assessment of acid production by various human oral micro-organisms when palatinose or leucrose is utilized.
PubMed:Di- and oligosaccharide substrate specificities and subsite binding energies of pig intestinal glucoamylase-maltase.
PubMed:Effects of frequent mouthrinses with palatinose and xylitol on dental plaque.
PubMed:Bacillus thermoamyloliquefaciens KP1071 alpha-glucosidase II is a thermostable M(r) 540,000 homohexameric alpha-glucosidase with both exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities.
PubMed:Embryotoxicity/teratogenicity study with isomaltulose (Palatinose) in rats.
PubMed:The effects of isomaltulose, isomalt, and isomaltulose-based oligomers on mineral absorption and retention.
PubMed:Urinary excretion by dogs of intravenously administered simple sugars.
PubMed:The effects of isomaltulose-based oligomers feeding and calcium deficiency on mineral retention in rats.
PubMed:Industrial application of immobilized biocatalysts in Japan.
PubMed:Transglucosylation with 6'-chloro-6'-deoxysucrose and immobilized isomaltulose-producing microorganisms using 2,2-dimethyl-1,3-dioxolane-4-methanol and its related compounds as acceptors. Steric and chemical requirement of the glucosyl acceptor.
PubMed:Characterization of alpha-glucosyltransferase from Pseudomonas mesoacidophila MX-45.
PubMed:Downstream processing of sucrose 6-glucosylmutase and production of isomaltulose, a non-cariogenic, low-caloric sweetener.
PubMed:Synthesis of dispirodioxanyl pseudo-oligosaccharides by selective protonic activation of isomeric glycosylfructoses in anhydrous hydrogen fluoride.
PubMed:Investigation of sucrose synthase from rice for the synthesis of various nucleotide sugars and saccharides.
PubMed:Selective protonic activation of isomeric glycosylfructoses with pyridinium poly(hydrogen fluoride) and synthesis of spirodioxanyl oligosaccharides.
PubMed:Trehalulose does not induce dental caries in rats infected with mutans streptococci.
PubMed:First purification and characterization of a sucrase-isomaltase from goose kidney microvillous membrane.
PubMed:Plaque formation of dietary isomaltulose in humans.
PubMed:Evaluation of a model for short-term clinical testing of cariogenicity.
PubMed:Usefulness of palatinose as a caloric sweetener for diabetic patients.
PubMed:Isomaltulose "palatinose". An anticariogenic substitute for glucose.
PubMed:Hydrolysis of alpha-D-glucopyranosyl-1,6-sorbitol and alpha-D-glucopyranosyl-1,6-mannitol by rat intestinal disaccharidases.
PubMed:[Sugar substitutes--new substances].
PubMed:New experiments on Palatinose (Isomaltulose) as a sugar substitute.
PubMed:[Effect of candy containing palatinose on human dental plaque formation].
PubMed:[A stepwise method of evaluating sugar substitutes--a preliminary study using enzymes. 2. Beta-fructosidase from yeast].
PubMed:Effects of parenteral palatinose on glucose metabolism in normal and streptozotocin diabetic rats.
PubMed:Palatinose as a potential parenteral nutrient: its metabolic effects and fate after oral and intravenous administration to dogs.
PubMed:Changes in blood glucose and insulin after an oral palatinose administration in normal subjects.
PubMed:[New sucrose substitutes].
PubMed:Isomaltulose production using immobilized cells.
PubMed:Microbiological aspects of some caloric sugar substitutes.
PubMed:New trends on sweeteners in Japan.
PubMed:[Non-cariogenicity of palatinose].
PubMed:[Caries-inducing activity of Palatinose syrup].
PubMed:Cariogenicity of isomaltulose (palatinose), sucrose and mixture of these sugars in rats infected with Streptococcus mutans E-49.
PubMed:Palatinose--a sucrose substitute. Pilot studies.
PubMed:The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici.
PubMed:[Effect of sugar substitutes on the growth and acid production of 2 types of acidogenic bacteria of the oral cavity].
PubMed:Virulence factors of Streptococcus mutans and dental caries prevention.
PubMed:Effect of frequent rinses with isomaltulose (Palatinose) solution on acid production in human dental plaque.
PubMed:[Oligosaccharides produced by Streptococcus mutans glucosyltransferase from sucrose with isomaltulose].
PubMed:Cariostatic effect of palatinose on experimental dental caries in rats.
PubMed:[Dental caries and palatinose, a structural isomer of sucrose].
PubMed:Effect of isomaltulose on acid production and insoluble glucan synthesis by Streptococcus mutans.
PubMed:Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats.
PubMed:Acid production from isomaltulose, sucrose, sorbitol, and xylitol in suspensions of human dental plaque.
PubMed:Carbohydrate transformations by immobilized cells.
PubMed:[Inhibitory mechanism of isomaltulose for insoluble glucan synthesis by Streptococcus mutans (author's transl)].
PubMed:[Analytical characterization of palatinit (author's transl)].
PubMed:[Formation of acids by cariogenically important streptococci from sugars and sugar alcohols with special reference to isomaltitol and isomaltulose].
PubMed:Human intestinal disaccharidases and hereditary disaccharide intolerance. The hydrolysis of sucrose, isomaltose, palatinose (isomaltulose), and a 1,6-alpha-oligosaccharide (isomalto-oligosaccharide) preparation.
 
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