Category:sweeteners, flavor enhancers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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Soluble in: |
| alcohol | | water, 12.48 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Flavor Type: sweet |
sweet sugar |
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | sweeteners, flavor enhancers |
Recommendation for advantame usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 25. Update in publication number(s): 29 |
Click here to view publication 25 |
| average usual ppm | average maximum ppm |
baked goods: | 20.00000 | 20.00000 |
beverages(nonalcoholic): | 1.35000 | 1.50000 |
beverages(alcoholic): | 3.00000 | 3.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | 40.00000 | 50.00000 |
condiments / relishes: | 3.00000 | 3.00000 |
confectionery froastings: | 3.75000 | 3.75000 |
egg products: | - | - |
fats / oils: | 3.00000 | 3.00000 |
fish products: | - | - |
frozen dairy: | 0.90000 | 1.00000 |
fruit ices: | - | - |
gelatins / puddings: | 3.75000 | 3.75000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | 0.75000 | 0.75000 |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | 0.90000 | 1.00000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | 3.75000 | 3.75000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Authority (EFSA) reference(s):
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Scientific Opinion on the safety of advantame for the proposed uses as a food additive View page or View pdf
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EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :56843846 |
National Institute of Allergy and Infectious Diseases:Data |
(3R)-4-[[(1S)-1-benzyl-2-methoxy-2-oxo-ethyl]amino]-3-[3-(3-hydroxy-4-methoxy-phenyl)propylamino]-4-oxo-butanoic acid hydrate |
Chemidplus:0714229206 |
References:
| (3R)-4-[[(1S)-1-benzyl-2-methoxy-2-oxo-ethyl]amino]-3-[3-(3-hydroxy-4-methoxy-phenyl)propylamino]-4-oxo-butanoic acid hydrate |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 56843846 |
Pubchem (sid): | 135268538 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| aminosweet | (3R)-4-[[(1S)-1- | benzyl-2-methoxy-2-oxo-ethyl]amino]-3-[3-(3-hydroxy-4-methoxy-phenyl)propylamino]-4-oxo-butanoic acid hydrate | N-[N-[3-(3- | hydroxy-4-methoxyphenyl)propyl-alpha-L-phenylalanine methyl ester, monohydrate | N-[N-[3-(3- | hydroxy-4-methoxyphenyl)propyl-alpha-laevo-phenylalanine methyl ester monohydrate | (N-[N-[3-(3- | hydroxy-4-methoxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester) monohydrate | (R)-3-[3-(3- | hydroxy-4-methoxyphenyl)propylamino]-4-[(S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino]-4-oxobutanoic acid hydrate |
Articles:
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