2-methyl-5-isopropyl pyrazine
2-isopropyl-5-methylpyrazine

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  13925-05-8 2-isoPropyl-5-methylpyrazine 95%

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Name: 2-methyl-5-propan-2-ylpyrazine CAS Number: 13925-05-8 3D/inchi FDA UNII: 818RIW504V Nikkaji Web: J101.205C CoE Number: 2268 XlogP3-AA: 1.30 (est) Molecular Weight: 136.19764000 Formula: C8 H12 N2 NMR Predictor: Predict (works with chrome, Edge or firefox) Category:flavoring agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 772 2-methyl-5-isopropylpyrazine DG SANTE Food Flavourings: 14.026 2-isopropyl-5-methylpyrazine FEMA Number: 3554 2-methyl-5-isopropylpyrazine FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 13925-05-8 ; 2-METHYL-5-ISOPROPYLPYRAZINE   Physical Properties: Appearance: colorless to pale yellow clear liquid (est) Assay: 97.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 0.97700 to 0.98400 @ 25.00 °C. Pounds per Gallon - (est).: 8.130 to 8.188 Refractive Index: 1.49200 to 1.49800 @ 20.00 °C. Boiling Point: 190.00 °C. @ 760.00 mm Hg Vapor Pressure: 0.850000 mmHg @ 25.00 °C. (est) Flash Point: 159.00 °F. TCC ( 70.56 °C. ) logP (o/w): 1.626 (est) Soluble in:   alcohol   water   water, 1901 mg/L @ 25 °C (est)   Organoleptic Properties: Odor Type: roasted green coffee nutty earthy Odor Description:at 0.10 % in dipropylene glycol. green coffee nutty earthy Flavor Type: green green Taste Description: green Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Ambles Nature et Chimie 2-ETHYL-(5or6)-METHYL PYRAZINE Axsyn For experimental / research use only. Pyrazine,2-methyl-5-(1-methylethyl)- BOC Sciences For experimental / research use only. 2-isoPropyl-5-methylpyrazine 95% Parchem 2-methyl-5-isopropyl pyrazine Chemical Sources Association Need This Item for Flavor/Food?: You can contact the Chemical Sources Association   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: Not determined Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavoring agents Recommendation for 2-methyl-5-isopropyl pyrazine usage levels up to:   not for fragrance use.   Maximised Survey-derived Daily Intakes (MSDI-EU): 0.024 (μg/capita/day) Maximised Survey-derived Daily Intakes (MSDI-USA): 0.40 (μg/capita/day) Structure Class: II Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 11 Click here to view publication 11   average usual ppm average maximum ppm baked goods: - 4.00000 beverages(nonalcoholic): - 4.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: - - fish products: - - frozen dairy: - 4.00000 fruit ices: - - gelatins / puddings: - 4.00000 granulated sugar: - - gravies: - - hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - - milk products: - - nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: - 4.00000 soups: - - sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):13925-05-8 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :61700 National Institute of Allergy and Infectious Diseases:Data 2-methyl-5-propan-2-ylpyrazine Chemidplus:0013925058   References:   2-methyl-5-propan-2-ylpyrazine NIST Chemistry WebBook: Search Inchi Pubchem (cid): 61700 Pubchem (sid): 135017897 Flavornet: 13925-05-8   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View HMDB (The Human Metabolome Database): HMDB37151 FooDB: FDB016146 YMDB (Yeast Metabolome Database): YMDB01446 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View   Potential Blenders and core components note For Odor No odor group found for these sulfuryl octanoate FL/FR sulfuryl butyrate FL/FR sulfuryl decanoate FL/FR sulfuryl hexanoate FL/FR sulfuryl isobutyrate FL/FR sulfuryl propionate FL/FR valeraldehyde dibutyl acetal FL/FR valeraldehyde propylene glycol acetal FL/FR alliaceous alliaceous methyl furfuryl disulfide FL/FR balsamic 2- acetyl furan FL/FR propyl benzoate FL/FR buttery acetyl propionyl FL/FR 3,4- hexane dione FL/FR camphoreous bornyl isobutyrate FL/FR caramellic coffee dione FL/FR cyclotene FL/FR ethyl 2-hydroxy-2-methyl butyrate FL/FR fenugreek oleoresin FL/FR chocolate chocolate pyrazine A FL/FR 2,6- dimethyl pyrazine FL/FR 2- methoxypyrazine FL/FR 2,4,5- trimethyl thiazole FL/FR cocoa 2- methyl butyraldehyde FL/FR coconut alpha- angelica lactone FL/FR gamma- heptalactone FL/FR coffee coffee difuran FL/FR furfuryl mercaptan FL/FR 1- hydroxy-2-butanone FL/FR 2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR coumarinic coumane FL/FR earthy 2- ethyl-3-methoxypyrazine FL/FR fatty coconut absolute FL/FR fermented valeraldehyde FL/FR floral para- cresyl laurate FL/FR fruity iso amyl nonanoate FL/FR methyl valerate FL/FR 3- methyl-2-butenal FL/FR green geranium thiazole FL/FR 2- heptyl furan FL/FR tiglaldehyde FL/FR herbal wormwood oil america FL/FR medicinal 2,6- xylenol FL/FR musty 2- acetyl pyrrole FL/FR 3- acetyl-2,5-dimethyl furan FL/FR hazelnut pyrazine FL/FR menthofuran FL/FR naphthyl ortho- methyl anisole FL/FR para- methyl anisole FL/FR nutty 3- acetyl pyridine FL/FR 2- acetyl-3-ethyl pyrazine FL/FR 2- acetyl-3-methyl pyrazine FL/FR 2- acetyl-3,5-dimethyl pyrazine FL/FR 2- acetyl-5-methyl furan FL/FR 3,5- cocoa pyrazine FL/FR 3,6- cocoa pyrazine FL/FR 2,3- dimethyl pyrazine FL/FR 4,5- dimethyl-2-ethyl-3-thiazoline FL/FR 2- ethyl pyrazine FL/FR 2- ethyl-4-methyl thiazole FL/FR filbert heptenone FL/FR filbert pyrazine FL/FR 2,6- lutidine FL/FR 2- methyl pyrazine FL/FR 5- methyl quinoxaline FL/FR 2- methyl thio-3,5 or 6-methyl pyrazine FL/FR 2- methyl-3-(methyl thio) pyrazine FL/FR 2- methyl-3-ethoxypyrazine FL/FR 2- methyl-3-propyl pyrazine FL/FR nutty cyclohexenone FL/FR nutty quinoxaline FL/FR sesame absolute FL/FR shoyu pyrazine FL/FR 2,3,5,6- tetramethyl pyrazine FL/FR 2,3,5- trimethyl pyrazine FL/FR vinyl sulfurol FL/FR popcorn 2- acetyl pyrazine FL/FR 2- acetyl thiazole FL/FR spicy 3-(2- furyl) acrolein FL/FR sulfurous benzothiazole FL/FR furfuryl thioacetate FL/FR S- furfuryl thioformate FL/FR 2- methyl 5-(methyl thio) furan FL/FR tonka whiskey lactone FL/FR vegetable 1- furfuryl pyrrole FL/FR mesityl oxide FL/FR waxy 2- tridecanone FL/FR woody sandalwood oil FL/FR For Flavor No flavor group found for these acetyl acetaldehyde dimethyl acetal FL 2- acetyl-6-methyl pyrazine FL bornyl isobutyrate FL/FR chocolate pyrazine A FL/FR coumane FL/FR cyclohexyl methyl pyrazine FL 2,5- diethyl thiazole FL 2,5- diethyl-4-methyl thiazole FL 6,7- dihydro-2,3-dimethyl-5H-cyclopentapyrazine FL dimethyl dihydrocyclopentapyrazine FL 6,7- dimethyl dihydrocyclopentapyrazine FL 2,5- dimethyl thiazole FL 2,5- dimethyl-3-thiofuroyl furan FL ethyl 2-hydroxy-2-methyl butyrate FL/FR 2- ethyl-3-methoxypyrazine FL/FR (Z+E)-5- ethyl-4-methyl-2-(2-butyl) thiazoline FL (Z+E)-5- ethyl-4-methyl-2-(2-methyl propyl) thiazoline FL 3-(2- furyl) acrolein FL/FR (E,E)-2,4- heptadien-1-ol FL 2- hexyl-5 or 6-keto-1,4-dioxane FL 2- methoxypyrazine FL/FR 2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR 2- methyl-3-(methyl thio) pyrazine FL/FR 2- methyl-3-ethoxypyrazine FL/FR peanut dithiazine FL 2- propyl pyridine FL para- salicylic acid FL sulfuryl butyrate FL/FR sulfuryl decanoate FL/FR sulfuryl hexanoate FL/FR sulfuryl isobutyrate FL/FR valeraldehyde propylene glycol acetal FL/FR 5- acetyl-2,3-dihydro-1,4-thiazine FL sulfuryl formate FL sulfuryl octanoate FL/FR sulfuryl propionate FL/FR valeraldehyde dibutyl acetal FL/FR alliaceous alliaceous benzyl mercaptan FL dicyclohexyl disulfide FL 2- methyl thioacetaldehyde FL bready 2- propionyl thiazole FL brown fenugreek oleoresin FL/FR 1- hydroxy-2-butanone FL/FR burnt furfuryl alcohol FL 2- methyl quinoxaline FL 2,6- xylenol FL/FR buttery 3,4- hexane dione FL/FR camphoreous ortho- methyl anisole FL/FR caramellic caramel furanone FL cyclotene FL/FR coffee coffee difuran FL/FR coffee dione FL/FR coffee pyrazine FL difurfuryl ether FL diisoamyl thiomalate FL 2,4- dimethyl thiazole FL 2- ethyl-4-methyl thiazole FL/FR furfuryl mercaptan FL/FR methyl furfuryl disulfide FL/FR methyl furfuryl thiol FL 2-iso propyl pyrazine FL 2- thiophene thiol FL corn chip 2- acetyl thiazole FL/FR 2- acetyl-2-thiazoline FL creamy alpha- angelica lactone FL/FR earthy difurfuryl sulfide FL 2- methyl-3-propyl pyrazine FL/FR fatty coconut absolute FL/FR 2- heptyl furan FL/FR (E,E)-2,4- nonadienal FL 2- tridecanone FL/FR fishy 4,5- dimethyl thiazole FL fruity furfuryl propionate FL 2,4- hexadien-1-ol FL methyl valerate FL/FR 3- methyl-2-butenal FL/FR propyl benzoate FL/FR tiglaldehyde FL/FR fusel 2- methyl butyraldehyde FL/FR green dihydroxyacetophenone (mixed isomers) FL 2,5- dimethyl thiophene FL geranium thiazole FL/FR 4- methyl thiazole FL green pepper distillates FL 2- vinyl pyrazine FL herbal wormwood oil america FL/FR lactonic gamma- heptalactone FL/FR meaty benzothiazole FL/FR 2,6- dimethyl pyrazine FL/FR 2- methyl 3-(methyl thio) furan FL mustard furfuryl methyl ether FL musty hazelnut pyrazine FL/FR menthofuran FL/FR 2- methyl 5-(methyl thio) furan FL/FR shoyu pyrazine FL/FR 2,3,5- trimethyl pyrazine FL/FR naphthyl para- methyl anisole FL/FR nutty 2- acetyl furan FL/FR 3- acetyl pyridine FL/FR 2- acetyl pyrrole FL/FR 3- acetyl-2,5-dimethyl furan FL/FR 2- acetyl-3-ethyl pyrazine FL/FR 2- acetyl-3-methyl pyrazine FL/FR 2- acetyl-3,5-dimethyl pyrazine FL/FR 2- acetyl-5-methyl furan FL/FR 3,6- cocoa pyrazine FL/FR 3,5- cocoa pyrazine FL/FR 3,5(6)- cocoa pyrazine FL 3,5- diethyl-2-methyl pyrazine FL 2,5- diethyl-3-methyl pyrazine FL 2,3- dimethyl pyrazine FL/FR 4,5- dimethyl-2-ethyl-3-thiazoline FL/FR 2,4- dimethyl-5-vinyl thiazole FL 2- ethyl pyrazine FL/FR 1- ethyl-2-acetyl pyrrole FL filbert heptenone FL/FR filbert pyrazine FL/FR european hazelnut oleoresin FL 2,6- lutidine FL/FR 2- methyl pyrazine FL/FR 5- methyl quinoxaline FL/FR 2- methyl thio-3,5 or 6-methyl pyrazine FL/FR nutty cyclohexenone FL/FR nutty quinoxaline FL/FR nutty thiazole FL peanut oxazole FL sesame absolute FL/FR 2,3,5,6- tetramethyl pyrazine FL/FR 2,4,5- trimethyl thiazole FL/FR vinyl sulfurol FL/FR onion furfuryl isopropyl sulfide FL popcorn 2- propionyl-2-thiazoline FL potato mesityl oxide FL/FR roasted 2- acetyl pyrazine FL/FR ethyl 3-(furfuryl thio) propionate FL furfuryl thioacetate FL/FR sulfurous butyl mercaptan FL ethyl methyl sulfide FL S- ethyl thioacetate FL S- furfuryl thioformate FL/FR furfuryl thiopropionate FL 2- methyl thiophene FL 2- thienyl mercaptan FL toasted acetyl propionyl FL/FR vegetable 1- furfuryl pyrrole FL/FR waxy para- cresyl laurate FL/FR winey iso amyl nonanoate FL/FR 5- ethyl-2-methyl pyridine FL valeraldehyde FL/FR woody sandalwood oil FL/FR whiskey lactone FL/FR   Potential Uses: FL coffee FL green FL nut   Occurrence (nature, food, other):note   cocoa butter Search Trop Picture   coffee Search PMC Picture   cyperus esculentus roasted Search Trop Picture   fish sauce Search PMC Picture   potato boiled potato Search PMC Picture   trassi Search Picture   Synonyms: 2- methyl-5-(1-methyl ethyl) pyrazine 2- methyl-5-(1-methylethyl)pyrazine 2- methyl-5-(propan-2-yl)pyrazine 2- methyl-5-isopropylpyrazine 2- methyl-5-propan-2-yl pyrazine 2- methyl-5-propan-2-ylpyrazine 5-iso propyl-2-methyl pyrazine 5-iso propyl-2-methylpyrazine 2-iso propyl-5-methyl pyrazine 2-iso propyl-5-methylpyrazine   pyrazine, 2-isopropyl-5-methyl-   pyrazine, 2-methyl-5-(1-methylethyl)-   Articles: US Patents:3,952,024 - Furfurylthioacetone US Patents:Certain 2,5-dimethyl-3-thiopyrazines

Notes: Present in boiled potato, coffee aroma, cocoa butter, fish sauce and roasted earth-almond (Cyperus esculentus)