Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 97.00 to 100.00
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.94400 to 0.95400 @ 25.00 °C.
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Pounds per Gallon - (est).: | 7.855 to 7.938
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Refractive Index: | 1.49200 to 1.50200 @ 20.00 °C.
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Boiling Point: | 95.00 °C. @ 14.00 mm Hg
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Boiling Point: | 205.00 to 206.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.353000 mmHg @ 25.00 °C. (est) |
Flash Point: | 170.00 °F. TCC ( 76.67 °C. )
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logP (o/w): | 1.966 (est) |
Soluble in: |
| alcohol | | propylene glycol | | water, slightly | | water, 488.9 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Type: nutty |
nutty meaty vegetable |
Odor Description:at 0.10 % in dipropylene glycol. nutty meaty vegetable |
Flavor Type: nutty |
green nutty |
Taste Description: green nutty |
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavoring agents |
Recommendation for 3,5-diethyl-2-methyl pyrazine usage levels up to: | | not for fragrance use.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.01 (μg/capita/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 19 |
Click here to view publication 19 |
| average usual ppm | average maximum ppm |
baked goods: | 1.00000 | 2.00000 |
beverages(nonalcoholic): | 0.50000 | 1.00000 |
beverages(alcoholic): | 0.10000 | 0.50000 |
breakfast cereal: | 1.00000 | 2.00000 |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.50000 | 1.00000 |
fruit ices: | - | - |
gelatins / puddings: | 0.50000 | 1.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | 0.50000 | 1.00000 |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | 1.00000 | 2.00000 |
soups: | 0.10000 | 0.50000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf
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Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf
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Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf
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EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :28906 |
National Institute of Allergy and Infectious Diseases:Data |
3,5-diethyl-2-methylpyrazine |
Chemidplus:0018138051 |
References:
Other Information:
Potential Blenders and core components note
For Odor |
chocolate |
cocoa hexenal FL/FR |
2- methoxy-3-methyl pyrazine FL/FR |
fruity |
allyl 2-ethyl butyrate FL/FR |
3- methyl-2-butenal FL/FR |
tropical thiazole FL/FR |
musty |
hazelnut pyrazine FL/FR |
nutty |
2- acetyl-3-methyl pyrazine FL/FR |
4,5- dimethyl-2-ethyl-3-thiazoline FL/FR |
2- methyl-3-(methyl thio) pyrazine FL/FR |
2- methyl-3-propyl pyrazine FL/FR |
2,3,5,6- tetramethyl pyrazine FL/FR |
For Flavor |
No flavor group found for these |
(Z+E)-5- ethyl-4-methyl-2-(2-butyl) thiazoline FL |
(Z+E)-5- ethyl-4-methyl-2-(2-methyl propyl) thiazoline FL |
2- methyl-2-thiazoline FL |
2- methyl-3-(methyl thio) pyrazine FL/FR |
thiazole FL |
alliaceous |
alliaceous |
tropical thiazole FL/FR |
cocoa |
cocoa hexenal FL/FR |
earthy |
2- methyl-3-propyl pyrazine FL/FR |
ethereal |
allyl 2-ethyl butyrate FL/FR |
fatty |
(E,E)-2,4- decadienal FL |
floral |
2- acetyl-5-methyl thiophene FL |
fruity |
3- methyl-2-butenal FL/FR |
green |
olive flavor FL |
4- penten-1-yl acetate FL |
musty |
2- ethoxythiazole FL |
hazelnut pyrazine FL/FR |
nutty |
3- acetyl-2,5-dimethyl thiophene FL |
2- acetyl-3-methyl pyrazine FL/FR |
2,5- diethyl-3-methyl pyrazine FL |
4,5- dimethyl-2-ethyl-3-thiazoline FL/FR |
2- methoxy-3-methyl pyrazine FL/FR |
2,3,5,6- tetramethyl pyrazine FL/FR |
popcorn |
2- propionyl-2-thiazoline FL |
radish |
3-( methyl thio) propyl mercaptoacetate FL |
sulfurous |
methyl 2-methyl-3-furyl disulfide FL |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| diethyl methyl pyrazine | 3,5- | diethyl-2-methylpyrazine | 2,6- | diethyl-3-methyl pyrazine | 2,6- | diethyl-3-methylpyrazine | 2- | methyl-3,5-diethyl-1,4-diazine | 2- | methyl-3,5-diethylpyrazine | | pyrazine, 3,5-diethyl-2-methyl- |
Articles:
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Found in potato, chicken, beef and pork, tea, coffee, galbanum oil and other foods. Flavouring agent
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