|
Category:cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 99.00 to 100.00
|
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.79600 to 0.79900 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 6.624 to 6.648
|
| Refractive Index: | 1.39100 to 1.39600 @ 20.00 °C.
|
| Melting Point: | -84.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 116.50 °C. @ 760.00 mm Hg
|
| Acid Value: | 2.00 max. KOH/g
|
| Vapor Pressure: | 19.900000 mmHg @ 25.00 °C. |
| Vapor Density: | 3.5 ( Air = 1 ) |
| Flash Point: | 56.00 °F. TCC ( 13.33 °C. )
|
| logP (o/w): | 1.310 |
| Soluble in: |
| | alcohol | | | dipropylene glycol | | | water, 1.90E+04 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor Type: green |
| sharp solvent green herbal fruity dairy spicy |
| Odor Description:at 10.00 % in dipropylene glycol. sharp solvent green herbal fruity dairy spice |
| sharp solvent green herbal fruity dairy |
Odor Description:Sharp solvent-like with green, herbal, fruity and dairy nuances
Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
| Flavor Type: green |
| green vegetable herbal fruity dairy |
Taste Description: Green, vegetative, herbal, fruity and dairy nuances
Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
| Odor and/or flavor descriptions from others (if found). |
| Bedoukian Research |
| METHYL ISOBUTYL KETONE ≥99.0%, FCC, Kosher, Special Order |
Odor Description:A sharp, green, herbal, fruity, spicy aroma
Used for its ethereal quality in fragrances. |
Taste Description:green
Used in spice, apple, whiskey, fruit and ripe banana flavors. |
| Alfrebro |
| 4-METHYL-2-PENTANONE NATURAL |
| Odor Description:Fruity, Ethereal, Spicy |
| Pell Wall Perfumes |
| Isobutyl Methyl Ketone |
Odor Description:Sharp, solvent-like, ethereal, fruity, green. Diffusive
Used to give an ethereal quality to fragrances, add ‘lift’ and is particularly useful where a fruity element is desired, where it can enhance the top note, giving a more juicy effect. Usage level is normally well below 1% of the fragrance concentrate. |
Cosmetic Information:
Suppliers:
| Alfrebro |
| 4-METHYL-2-PENTANONE NATURAL
Odor: Fruity, Ethereal, Spicy |
| Arkema |
| Methylisobutylketone
Odor: characteristic Use: MIBK (Methylisobutylketone) is a stable, medium evaporating liquid and compatible with many organic materials, which makes it a good industrial solvent. MIBK can also be used in order to extract, separate and purify various products. It is used in the pharmaceutical, agrochemical industries, in fine chemistry… |
| Eastman Chemical |
| Eastman™ Methyl Isobutyl Ketone
Odor: characteristic Use: Eastman™ Methyl Isobutyl Ketone (MIBK) is a medium-evaporating solvent. It is an active solvent for many synthetic resins including cellulosics, vinyl copolymers, acrylics, alkyds, polyesters, and epoxies. It is very useful in developing high-solids coatings because of its combination of high solvent activity and low density.
In addition to its use as a solvent for inks, coatings, and adhesives, MIBK is used as an extraction agent in the dewaxing and deoiling of petroleum products. It is also used in the manufacture of germicides, fungicides, pharmaceuticals, electroplating solutions, and as a denaturant in many ethanol formulations. |
| ECSA Chemicals |
| METHYL ISOBUTYL KETONE RPE-ACS-FOR ANALYSIS-
|
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ECSA Chemicals |
| METHYL ISOBUTYL KETONE
|
| EMD Millipore |
| For experimental / research use only. |
| isoButyl Methyl Ketone
|
| Glentham Life Sciences |
| 4-Methyl-2-pentanone
|
| Inoue Perfumery |
| isoBUTYL METHYL KETONE
|
| Moellhausen |
| METHYL ISOBUTYL KETONE
Odor: fresh, fruity, somewhat burnt; banana-like with dairy nuance |
| Pell Wall Perfumes |
| Isobutyl Methyl Ketone
Odor: Sharp, solvent-like, ethereal, fruity, green. Diffusive Use: Used to give an ethereal quality to fragrances, add ‘lift’ and is particularly useful where a fruity element is desired, where it can enhance the top note, giving a more juicy effect. Usage level is normally well below 1% of the fragrance concentrate. |
| Penta International |
| METHYL ISOBUTYL KETONE NATURAL
|
| Penta International |
| METHYL ISOBUTYL KETONE
|
| Shiva Chemicals and Pharmaceuticals |
| Methyl Iso Butyl Ketone (MIBK)
|
| Sigma-Aldrich |
| 4-Methyl-2-pentanone, ≥99%, FCC
Odor: spicy; ethereal; fruity |
| Certified Food Grade Products |
| Silver Fern Chemical |
| Methyl Isobutyl Ketone (MIBK)
Odor: characteristic Use: Methyl isobutyl ketone is primarily used as a solvent for paints, varnishes, nitrocellulose, lacquers, organic synthesis, and a denaturant for alcohol. |
| TCI AMERICA |
| For experimental / research use only. |
| 4-Methyl-2-pentanone >99.5%(GC)
|
| Wedor Corporation |
| METHYL ISOBUTYL KETONE
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 11 - Highly flammable.
R 20 - Harmful by inhalation.
R 36/37 - Irritating to eyes and respiratory system.
R 66 - Repeated exposure may cause skin dryness or cracking.
S 02 - Keep out of the reach of children.
S 09 - Keep container in a well-ventilated place.
S 16 - Keep away from sources of ignition - No Smoking.
S 29 - Do not empty into drains.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 2080 mg/kg
(Smyth et al., 1951)
oral-mouse LD50 [sex: M] 2670 mg/kg
(Tanii et al., 1986)
oral-mouse LD50 1200 mg/kg
(McOmie & Anderson, 1949a)
intraperitoneal-guinea pig LD50 800 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4748, 1982.
oral-guinea pig LD50 1600 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4748, 1982.
unreported-mammal (species unspecified) LD50 1396 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
intraperitoneal-mouse LD50 268 mg/kg
Shell Chemical Company. Unpublished Report. Vol. -, Pg. 7, 1961.
oral-mouse LD50 1900 mg/kg
National Technical Information Service. Vol. OTS0535383
intraperitoneal-rat LD50 400 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4748, 1982.
oral-rat LD50 2080 mg/kg
Union Carbide Data Sheet. Vol. 4/25/1958
|
| Dermal Toxicity: |
skin-rabbit LD50 > 3000 mg/kg
National Technical Information Service. Vol. OTS0535383
|
| Inhalation Toxicity: |
inhalation-rat LC50 100000 mg/m3
National Technical Information Service. Vol. OTS0535383
inhalation-mouse LC50 23300 mg/m3
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(11), Pg. 52, 1973.
inhalation-guinea pig LCLo 68900 mg/m3/3H
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
CARDIAC: PULSE RATE
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
National Technical Information Service. Vol. OTS0535383
inhalation-man TCLo 2290 mg/m3
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
National Technical Information Service. Vol. OTS0535383
|
Safety in Use Information:
| Category: | | cosmetic, flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for isobutyl methyl ketone usage levels up to: | | | 0.5000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 6.10 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 6.30000 |
| beverages(nonalcoholic): | - | 6.30000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 6.30000 |
| fruit ices: | - | 6.30000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 6.30000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
|
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
|
Flavouring Group Evaluation 63 (FGE.63): Consideration of aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th meeting) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated by EFSA in FGE.07 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
|
Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf
|
Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
|
| EPI System: View |
| EPA-Iris:IRIS |
| NIOSH International Chemical Safety Cards:search |
| NIOSH Pocket Guide:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):108-10-1 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :7909 |
| National Institute of Allergy and Infectious Diseases:Data |
| WISER:UN 1245 |
| WGK Germany:1 |
| 4-methylpentan-2-one |
| Chemidplus:0000108101 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:108-10-1 |
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| acidic |
2- ethyl butyric acid
FL/FR |
| aldehydic |
agrumen nitrile
FR |
| alliaceous |
dibutyl sulfide
FL/FR |
dipropyl disulfide
FL/FR |
| animal |
iso butyl quinoline
FR |
| anisic |
amyl furoate
FL/FR |
estragole
FL/FR |
ocimum basilicum leaf oil america
FL/FR |
| balsamic |
siam benzoin absolute
FL/FR |
cinnamyl formate
FL/FR |
christmas pine fragrance
FR |
| bready |
coffee furanone
FL/FR |
| caramellic |
2-iso butyl-3-methyl pyrazine
FL/FR |
| chocolate |
2,4,5- trimethyl thiazole
FL/FR |
| citrus |
(Z)-4- decenal
FL/FR |
iso decyl acetate
FR |
methyl heptenone
FL/FR |
ocimene quintoxide
FL/FR |
| coconut |
alpha- angelica lactone
FL/FR |
| coumarinic |
phthalide
FL/FR |
| earthy |
geosmin
FL/FR |
(S)-1- octen-3-ol
FL/FR |
| ethereal |
butyl acetate
FL/FR |
ethyl 4-pentenoate
FL/FR |
2- methyl valeraldehyde
FL/FR |
iso propyl formate
FL/FR |
| fatty |
2,4- decadien-1-ol
FL/FR |
(E,E)-2,4- decadien-1-ol
FL/FR |
2- octenal
FL/FR |
(E)-2- octenal
FL/FR |
| floral |
iso amyl angelate
FL/FR |
alpha- amyl cinnamaldehyde
FL/FR |
cassis cyclohexene
FR |
cassis oxime 10%
FR |
cilantro herb oil egypt
FL/FR |
cymbopogon validus leaf oil
FR |
dictamnus hispanicus oil
FR |
dihydrocitronellyl ethyl ether
FR |
dihydrorose oxide
FR |
dimethyl benzyl carbinyl butyrate
FL/FR |
2,4- dimethyl-3-cyclohexene-1-methanol
FR |
geranium oil africa
FL/FR |
geranium oil egypt
FL/FR |
jasmin absolute egypt (from concrete)
FL/FR |
linden flower absolute
FR |
magnolia flower oil CO2 extract
FL/FR |
melaleuca ericifolia leaf oil
FR |
menthadienyl formate
FR |
para- methyl benzyl acetate
FL/FR |
methyl benzyl acetate (mixed ortho-,meta-,para-)
FL/FR |
neryl formate
FL/FR |
nonan-3-yl acetate
FL/FR |
3- nonanone
FL/FR |
2- pentyl cyclopentanone
FR |
iso phytol
FL/FR |
prenyl salicylate
FL/FR |
reseda absolute
FR |
(Z)- rose oxide
FL/FR |
rose pyran
FR |
5- tricyclodecenyl acetate
FR |
| fruity |
iso amyl acetate
FL/FR |
para- anisyl propionate
FL/FR |
balsam specialty
FR |
3- butyl bicyclo[3.2.1]-6-octen-2-one
FR |
ethyl 2-ethyl acetoacetate
FL/FR |
2- methyl butyl isovalerate
FL/FR |
2- nonanone
FL/FR |
propyl acetate
FL/FR |
tropical indene
FR |
| green |
acetaldehyde butyl phenethyl acetal
FL/FR |
agrumen aldehyde
FR |
birch leaf specialty
FR |
iso butyl heptanoate
FL/FR |
butyl heptanoate
FL/FR |
2-iso butyl thiazole
FL/FR |
2-sec- butyl thiazole
FL/FR |
S-sec- butyl thioisovalerate
FL/FR |
carrot leaf oil (daucus carota ssp.maximus)
FR |
chrysanthemum carbaldehyde
FR |
cortex pyridine
FL/FR |
dicyclopentadiene propionate
FR |
galbanum decatriene
FL/FR |
heptanal (aldehyde C-7)
FL/FR |
1- heptanol
FL/FR |
heptyl benzoate
FL/FR |
herbal cyclohexane
FR |
(Z)-4- hexen-1-ol
FL/FR |
(Z)-2- hexen-1-ol
FL/FR |
(Z)-3- hexen-1-yl tiglate
FL/FR |
3- hexenyl 2-methyl butyrate
FL/FR |
hexyl hexanoate
FL/FR |
hexyl tiglate
FL/FR |
english ivy leaf absolute
FR |
(Z)- leaf acetal
FL/FR |
marigold pot absolute
FL/FR |
methyl heptine carbonate
FL/FR |
6- methyl-3-hepten-2-one
FL/FR |
nerol oxide
FL/FR |
(Z,Z)-3,6- nonadien-1-ol
FL/FR |
1- penten-3-ol
FL/FR |
3- propyl bicyclo(3.2.1)-6-octen-2-one
FR |
seaweed absolute (fucus vesiculosus et serratus)
FL/FR |
terpinyl propionate
FL/FR |
triplal / ethyl anthranilate schiff's base
FR |
| herbal |
6- acetoxydihydrotheaspirane
FL/FR |
alpha- amyl cinnamyl formate
FL/FR |
iso amyl heptanoate
FL/FR |
anethum graveolens herb oil
FL/FR |
anethum graveolens herb tincture
FL/FR |
anthemis nobilis flower extract
FL/FR |
anthemis nobilis flower oil roman
FL/FR |
apium graveolens seed oil
FL/FR |
apium graveolens seed oil india
FL/FR |
artemisia alba oil
FR |
artemisia ludoviciana oil
FR |
sweet basil absolute
FL/FR |
buchu mercaptan acetate
FL/FR |
butyl levulinate
FL/FR |
3- butylidene phthalide
FL/FR |
(+)-alpha- campholenic aldehyde
FL/FR |
chamomile propionate
FR |
chamomile valerate
FR |
chrysanthemum ketone
FR |
coriander oleoresin
FL/FR |
dill weed oil cuba
FL/FR |
dill weed oil reunion
FL/FR |
dimethyl benzyl carbinyl crotonate
FL/FR |
dimethyl benzyl carbinyl formate
FL/FR |
2-(2,4- dimethyl-3-cyclohexene-1-yl)-4,4-dimethyl-1,3-oxathiane
FR |
cis- herbal cyclohexane
FR |
herbal dioxane
FR |
herbal heptane
FR |
hop absolute
FL/FR |
hop oil
FL/FR |
lantana camara flower oil
FR |
linalyl formate
FL/FR |
linalyl octanoate
FL/FR |
marigold oil mexico
FL/FR |
melaleuca leucadendron var. cajuputi leaf oil
FL/FR |
1-para- menthen-9-yl acetate
FL/FR |
1-(2- methyl allyl oxy) heptane
FR |
methyl hexyl ether
FL/FR |
(E)-6- methyl-3-hepten-2-one
FL/FR |
monarda fistulosa oil
FR |
myrtle oil
FL/FR |
nonisyl formate
FR |
3- octanon-1-ol
FL/FR |
1- octen-3-yl acetate
FL/FR |
oregano specialty
FR |
origanum oil
FL/FR |
origanum oil greece
FL/FR |
curled parsley seed oil
FL/FR |
perilla leaf oil
FL/FR |
perillaldehyde
FL/FR |
petroselinum crispum seed oil CO2 extract
FL/FR |
phenyl acetaldehyde diisoamyl acetal
FR |
prenyl senecioate
FL/FR |
3- propylidene phthalide
FL/FR |
rosmarinus officinalis extract
FL/FR |
rosmarinus officinalis tincture
FL/FR |
rue oil
FL/FR |
rue oil cuba
FL/FR |
tagete oil CO2 extract
FL/FR |
tagete oil egypt
FL/FR |
tagete oil south africa
FL/FR |
tagete oil turkey
FL/FR |
tagete oil zambia
FL/FR |
theaspirane
FL/FR |
thyme absolute
FL/FR |
tricyclodecenyl isobutyrate
FR |
tricyclodecenyl propionate
FR |
tricyclodecyl acetate
FR |
viridiflorol
FL/FR |
wormwood oil america
FL/FR |
wormwood oil italy
FL/FR |
wormwood oil poland
FL/FR |
| minty |
carvyl acetate
FL/FR |
(-)- menthone
FL/FR |
(-)-iso pulegol
FL/FR |
| mossy |
treemoss absolute
FR |
| musty |
cocoa butenal
FL/FR |
| orris |
orris capronate
FL/FR |
| soapy |
methyl anthranilate / hexyl cinnamaldehyde schiff's base
FR |
| spicy |
boldus leaf oil
CS |
iso butyl angelate
FL/FR |
trans- carveol
FL/FR |
(-)- cubenol
FL/FR |
cuminaldehyde
FL/FR |
iso cyclogeraniol (IFF)
FR |
origanum majorana oil
FL/FR |
outdoors specialty
FR |
spicy carbonate
FR |
| sulfurous |
3-( methyl thio) hexanol
FL/FR |
| tonka |
(±)- dihydromint lactone
FL/FR |
| waxy |
ethyl laurate
FL/FR |
2- nonanol
FL/FR |
| woody |
cinnamyl tiglate
FL/FR |
dalbergia sissoo leaf oil
FR |
2- decalinyl acetate
FR |
alpha- farnesene
FL/FR |
alpha- farnesene isomer
FL/FR |
patchouli absolute
FR |
verdoxan
FR |
| yeasty |
2- octen-4-one
FL/FR |
| For Flavor |
| No flavor group found for these |
6- acetoxydihydrotheaspirane
FL/FR |
4- acetyl-2-isopropenyl pyridine
FL |
iso amyl angelate
FL/FR |
alpha- amyl cinnamyl formate
FL/FR |
amyl furoate
FL/FR |
para- anisyl propionate
FL/FR |
benzyl methyl tiglate
FL |
iso butyl heptanoate
FL/FR |
4- butyl thiazole
FL |
2-sec- butyl thiazole
FL/FR |
S-sec- butyl thioisovalerate
FL/FR |
trans- carveol
FL/FR |
cinnamyl tiglate
FL/FR |
(±)-(cis+trans)-1,2- dihydroperillaldehyde
FL |
dimethyl benzyl carbinyl crotonate
FL/FR |
dimethyl benzyl carbinyl formate
FL/FR |
ethyl 4-pentenoate
FL/FR |
fig leaf absolute
FL |
heptyl benzoate
FL/FR |
(E,E)-2,4- hexadien-1-ol
FL |
magnolia flower oil CO2 extract
FL/FR |
melaleuca leucadendron var. cajuputi leaf oil
FL/FR |
methyl benzyl acetate (mixed ortho-,meta-,para-)
FL/FR |
(E)-6- methyl-3-hepten-2-one
FL/FR |
6- methyl-3-hepten-2-one
FL/FR |
nonan-3-yl acetate
FL/FR |
3- octanon-1-ol
FL/FR |
(S)-1- octen-3-ol
FL/FR |
2- octenal
FL/FR |
3- octyl butyrate
FL |
perilla leaf oil
FL/FR |
prenyl senecioate
FL/FR |
2- propyl thiazole
FL |
seaweed absolute (fucus vesiculosus et serratus)
FL/FR |
ortho- vinyl anisole
FL |
viridiflorol
FL/FR |
|
althaea officinalis root tincture
FL |
| acidic |
| acidic |
2- ethyl butyric acid
FL/FR |
propionic acid
FL |
| alliaceous |
allyl thiopropionate
FL |
dipropyl disulfide
FL/FR |
| celery |
3- butylidene phthalide
FL/FR |
| cheesy |
2- nonanone
FL/FR |
| citrus |
(Z)-4- decenal
FL/FR |
| cooling |
theaspirane
FL/FR |
| coumarinic |
phthalide
FL/FR |
| creamy |
althaea officinalis root extract
FL |
alpha- angelica lactone
FL/FR |
| earthy |
geosmin
FL/FR |
| estery |
propyl acetate
FL/FR |
| ethereal |
butyl acetate
FL/FR |
methyl hexyl ether
FL/FR |
| fatty |
2,4- decadien-1-ol
FL/FR |
(E,E)-2,4- decadien-1-ol
FL/FR |
(E)-2- octenal
FL/FR |
| floral |
dimethyl benzyl carbinyl butyrate
FL/FR |
geranium oil africa
FL/FR |
geranium oil egypt
FL/FR |
jasmin absolute egypt (from concrete)
FL/FR |
| fruity |
iso amyl acetate
FL/FR |
buchu mercaptan acetate
FL/FR |
butyl heptanoate
FL/FR |
ethyl 2-ethyl acetoacetate
FL/FR |
2,4- hexadien-1-ol
FL |
hexyl hexanoate
FL/FR |
linalyl octanoate
FL/FR |
1-para- menthen-9-yl acetate
FL/FR |
para- methyl benzyl acetate
FL/FR |
2- methyl butyl isovalerate
FL/FR |
neryl formate
FL/FR |
iso propyl formate
FL/FR |
tagete oil CO2 extract
FL/FR |
tagete oil south africa
FL/FR |
tagete oil turkey
FL/FR |
tagete oil zambia
FL/FR |
| green |
acetaldehyde butyl phenethyl acetal
FL/FR |
anethum graveolens herb tincture
FL/FR |
iso butyl angelate
FL/FR |
2-iso butyl thiazole
FL/FR |
2-iso butyl-3-methyl pyrazine
FL/FR |
(+)-alpha- campholenic aldehyde
FL/FR |
celery distillates
FL |
cocoa butenal
FL/FR |
cortex pyridine
FL/FR |
dibutyl sulfide
FL/FR |
dihydroxyacetophenone (mixed isomers)
FL |
alpha- farnesene
FL/FR |
alpha- farnesene isomer
FL/FR |
galbanum decatriene
FL/FR |
heptanal (aldehyde C-7)
FL/FR |
heptanal 2,3-butane diol acetal
FL |
(Z)-4- hexen-1-ol
FL/FR |
(Z)-2- hexen-1-ol
FL/FR |
(Z)-3- hexen-1-yl tiglate
FL/FR |
3- hexenyl 2-methyl butyrate
FL/FR |
2- hexyl pyridine
FL |
hexyl tiglate
FL/FR |
horseradish oil
FL |
(Z)- leaf acetal
FL/FR |
marigold pot absolute
FL/FR |
methyl heptenone
FL/FR |
methyl heptine carbonate
FL/FR |
4- methyl thiazole
FL |
nerol oxide
FL/FR |
3- nonanone
FL/FR |
ocimene quintoxide
FL/FR |
1- octen-3-yl acetate
FL/FR |
4- penten-1-yl acetate
FL |
1- penten-3-ol
FL/FR |
3- propylidene phthalide
FL/FR |
(Z)- rose oxide
FL/FR |
terpinyl propionate
FL/FR |
| herbal |
iso amyl heptanoate
FL/FR |
anethum graveolens herb oil
FL/FR |
anthemis nobilis flower extract
FL/FR |
anthemis nobilis flower oil roman
FL/FR |
apium graveolens seed oil
FL/FR |
apium graveolens seed oil india
FL/FR |
sweet basil absolute
FL/FR |
butyl levulinate
FL/FR |
celery seed oleoresin
FL |
cilantro herb oil egypt
FL/FR |
coriander oleoresin
FL/FR |
dill weed oil cuba
FL/FR |
dill weed oil reunion
FL/FR |
hop absolute
FL/FR |
hop oil
FL/FR |
ilex paraguariensis leaf extract
FL |
linalyl formate
FL/FR |
marigold oil mexico
FL/FR |
ocimum basilicum leaf oil america
FL/FR |
origanum majorana oil
FL/FR |
origanum oil
FL/FR |
origanum oil greece
FL/FR |
curled parsley seed oil
FL/FR |
petroselinum crispum seed oil CO2 extract
FL/FR |
prenyl salicylate
FL/FR |
rosmarinus officinalis extract
FL/FR |
rosmarinus officinalis tincture
FL/FR |
rue oil
FL/FR |
rue oil cuba
FL/FR |
tagete oil egypt
FL/FR |
thyme absolute
FL/FR |
wormwood oil america
FL/FR |
wormwood oil italy
FL/FR |
wormwood oil poland
FL/FR |
| lactonic |
(±)- dihydromint lactone
FL/FR |
| licorice |
estragole
FL/FR |
| metallic |
3-( methyl thio) hexanol
FL/FR |
| minty |
carvyl acetate
FL/FR |
(-)- menthone
FL/FR |
(-)-iso pulegol
FL/FR |
| nutty |
coffee furanone
FL/FR |
2,4,5- trimethyl thiazole
FL/FR |
| oily |
iso phytol
FL/FR |
| orris |
orris capronate
FL/FR |
| seafood |
1,4- dithiane
FL |
| solvent |
1- heptanol
FL/FR |
methyl phenyl sulfide
FL |
| spicy |
siam benzoin absolute
FL/FR |
cinnamyl formate
FL/FR |
(-)- cubenol
FL/FR |
cuminaldehyde
FL/FR |
myrtle oil
FL/FR |
perillaldehyde
FL/FR |
| tropical |
alpha- amyl cinnamaldehyde
FL/FR |
| vegetable |
2- methyl valeraldehyde
FL/FR |
2- octen-4-one
FL/FR |
| waxy |
ethyl laurate
FL/FR |
(Z,Z)-3,6- nonadien-1-ol
FL/FR |
2- nonanol
FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| iso | butylmethyl ketone | | iso | hexanone | | | hexone | | | ketone, isobutyl methyl | | | methyl 2-methylpropyl ketone | | 4- | methyl 2-pentanone | | | methyl iso-butyl ketone | | | methyl isobutyl ketone | | | methyl isobutyl ketone natural | | 4- | methyl pentan-2-one | | 2- | methyl propyl methyl ketone | | 4- | methyl-2-oxopentane | | 4- | methyl-2-pentanone | | 2- | methyl-4-oxopentane | | 2- | methyl-4-pentanone | | | methyl-isobutylketone | | 4- | methyl-pentan-2-one | | | methylisobutylketone | | 4- | methylpentan-2-one | | 2- | methylpropyl methyl ketone | | | mibk | | 2- | pentanone, 4-methyl- | | iso | propyl acetone |
Articles:
| Info:Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) |
| PubMed:The Japan Flavour and Fragrance Materials Association's (JFFMA) safety assessment of acetal food flavouring substances uniquely used in Japan. |
| PubMed:Influence of manufacturing conditions and crop season on the formation of 4-mercapto-4-methyl-2-pentanone in Japanese green tea (sen-cha). |
| PubMed:Changes in analytical and volatile compositions of red wines induced by pre-fermentation heat treatment of grapes. |
| PubMed:Quantification of Polyfunctional Thiols in Wine by HS-SPME-GC-MS Following Extractive Alkylation. |
| PubMed:Volatile compounds responsible for aroma of Jutrzenka liquer wine. |
| PubMed:Hydrothermal conversion of bamboo: identification and distribution of the components in solid residue, water-soluble and acetone-soluble fractions. |
| PubMed:A powerful methodological approach combining headspace solid phase microextraction, mass spectrometry and multivariate analysis for profiling the volatile metabolomic pattern of beer starting raw materials. |
| PubMed:Influence of volatile thiols in the development of blackcurrant aroma in red wine. |
| PubMed:Inhalation two-generation reproductive toxicity study of methyl isobutyl ketone in rats. |
| PubMed:Developmental toxicity evaluation of inhaled methyl isobutyl ketone in Fischer 344 rats and CD-1 mice. |
| PubMed:Color, lipid oxidation, sensory quality, and aroma compounds of beef steaks displayed under different levels of oxygen in a modified atmosphere package. |
| PubMed:Sensory and chemical characterisation of the aroma of Prieto Picudo rosé wines: the differential role of autochthonous yeast strains on aroma profiles. |
| PubMed:Determination of cadmium, copper, and lead in sodium chloride food salts by flame atomic absorption spectroscopy. |
| PubMed:Determination of semduramicin in poultry feed additive, premixture and compound feed by liquid chromatography and UV spectrophotometric detection after post-column derivatisation. |
| PubMed:Identification of potent odorants in Japanese green tea (Sen-cha). |
| PubMed:Screening method for determination of high levels of cadmium, lead, and copper in foods by polarized Zeeman atomic absorption spectrometry using discrete nebulization technique. |
| PubMed:New factor characterizing the in-mouth release of odorants (volatile thiols): compositional changes in odorants exhaled from the human nose during drinking. |
| PubMed:Cobalt content of foods and diets in a Spanish population (short communication). |
| PubMed:Atomic absorption spectrophotometric method for determination of polydimethylsiloxane residues in pineapple juice: collaborative study. |
| PubMed:Aroma composition changes in early season grapefruit juice produced from thermal concentration. |
| PubMed:Occurrence of polyfunctional thiols in fresh lager beers. |
| PubMed:Combinatorial synthesis and sensorial properties of mercapto primary alcohols and analogues. |
| PubMed:Identification of potent odorants in different green tea varieties using flavor dilution technique. |
| PubMed:Determination of tin, vanadium, iron, and molybdenum in various matrices by atomic absorption spectrometry using a simultaneous liquid-liquid extraction procedure. |
| PubMed:Determination of tin in canned fruits and vegetables by atomic absorption spectrometry and liquid-liquid extraction. |
| PubMed:Atomic absorption spectrophotometric determination of chromium in foods. |
| PubMed:[Evaluation of heavy metal contamination of potatoes from various regions of Poland]. |
| PubMed:Electrothermal atomic absorption spectrometric determination of selenium in foods and diets. |
| PubMed:Identification and characterization of bacteria isolated under selective pressure of volatile organic compounds. |
| PubMed:Quantitative evaluation of sensory irritating and neurobehavioural properties of aliphatic ketones in mice. |
| PubMed:Multiple microbial activities for volatile organic compounds reduction by biofiltration. |
|
Present in orange, lemon, concord grape, vinegar, cheeses, cooked beef, roasted peanut and other foodstuffs. Flavouring ingredient
Methyl isobutyl ketone (MIBK) is an organic solvent. MIBK is among the top ten most popular organic solvents used in industry. MIBK is occasionally found as a volatile component of urine. MIBK in urine is considered as a biological marker of occupational exposure to this solvent. Olfactory perception is significant but adaptation may occur. The typical toxicity effects of MIBK in humans exposed at 50 to 100 ppm are mucous membrane irritation and weak effects on the central nervous system (CNS) such as headache. Visual dysfunction has been reported in workers exposed to a mixture of organic solvents containing MIBK. Memory impairment was detected in clinical observation on a 44-year-old man who had been exposed to MIBK at 100 ppm for more than 10 years. Regarding to the route of absorption, skin penetration of MIBK is substantial. (PMID: 12592578, 17485256, 16464817, 5556886)
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3D/inchi