|
Category:flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 97.00 to 100.00
|
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.82000 to 0.82300 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 6.823 to 6.848
|
| Refractive Index: | 1.42200 to 1.42600 @ 20.00 °C.
|
| Melting Point: | -36.00 to -34.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 175.00 to 176.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 104.00 to 105.00 °C. @ 50.00 mm Hg
|
| Acid Value: | 1.00 max. KOH/g
|
| Vapor Pressure: | 0.325000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 165.00 °F. TCC ( 73.89 °C. )
|
| logP (o/w): | 2.620 |
| Soluble in: |
| | alcohol | | | fixed oils | | | water, 1940 mg/L @ 25 °C (est) | | | water, 1670 mg/L @ 25 °C (exp) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Type: green |
Odor Strength:medium ,
recommend smelling in a 10.00 % solution or less |
| Substantivity:12 hour(s) at 100.00 % |
| musty leafy violet herbal green sweet woody peony |
Odor Description:at 10.00 % in dipropylene glycol. musty leafy violet herbal green sweet woody peony
Luebke, William tgsc, (1984) |
| Odor sample from: Givaudan Corporation |
| musty pungent leafy green vegetable fruity apple banana |
Odor Description:at 1.00 %. Musty, pungent, leafy green, with vegetative and fruity nuances of apple and banana
Mosciano, Gerard P&F 26, No. 3, 80, (2001) |
| Flavor Type: solvent |
| solvent fermented oily nutty fatty green aldehydic |
Taste Description: at 1.00 - 10.00 ppm. Solvent-like, fermented with oily nutty and fatty notes, and a slight green aldehydic under note
Mosciano, Gerard P&F 26, No. 3, 80, (2001) |
| Odor and/or flavor descriptions from others (if found). |
| Alfrebro |
| n-HEPTYL ALCOHOL NATURAL |
| Odor Description:Citrus, Heavy, Oily |
Cosmetic Information:
Suppliers:
| Acme Synthetic Chemicals |
| Heptyl Alcohol 99% Min by GC
|
| Advanced Biotech |
| 1 HEPTANOL NATURAL
|
| Alfrebro |
| n-HEPTYL ALCOHOL NATURAL
Odor: Citrus, Heavy, Oily |
| Arkema |
| Oleris® n-Heptanol
Odor: characteristic Use: Oleris® n-Heptanol is mainly used as a synthesis intermediate in the fragrances and flavors industry, in plasticizers for polymers and in cosmetics. |
| Aurochemicals |
| HEPTANOL, Natural
|
| BOC Sciences |
| For experimental / research use only. |
| 1-Heptanol
|
| CJ Latta & Associates |
| HEPTANOL
|
| EMD Millipore |
| For experimental / research use only. |
| 1-Heptanol
|
| Fleurchem |
| alcohol C-7 natural
|
| Fleurchem |
| alcohol C-7
|
| Grau Aromatics |
| HEPTANOL-1 FCC
|
| Inoue Perfumery |
| HEPTANOL
|
| Jiangyin Healthway |
| Heptanol Natural99%
|
| New functional food ingredients |
| Lluch Essence |
| ALCOHOL C-07
Odor: HERBACEOUS, MUSTY, GREEN |
| M&U International |
| Nat. Heptanol
|
| M&U International |
| Nat. Heptanol
|
| Nagar Haveli Perfumes & Aromatics |
| 1 - Heptanol
Odor: Musty leafy violet herbal green sweet woody peony, weak alcohol |
| Nagar Haveli Perfumes & Aromatics |
| 1 - Heptanol
Natural Odor: Musty leafy violet herbal green sweet woody peony, weak alcohol |
| OQEMA |
| Heptyl Alcohol natural
|
| Penta International |
| HEPTYL ALCOHOL NATURAL
|
| Penta International |
| HEPTYL ALCOHOL
|
| Prodasynth |
| HEPTANOL
(> 98%) |
| R C Treatt & Co Ltd |
| 1-Heptanol
|
| Sigma-Aldrich |
| Heptyl alcohol, ≥97%, FCC, FG
Odor: apple; apricot; coconut; musty; oily; woody; citrus; nutty; fruity; strawberry; vanilla; vegetable; meaty; green; wine-like |
| Certified Food Grade Products |
| Sigma-Aldrich |
| Heptyl alcohol, natural, 98%
|
| SRS Aromatics |
| HEPTAN-1-OL FCC
|
| TCI AMERICA |
| For experimental / research use only. |
| 1-Heptanol >98.0%(GC)
|
| United International |
| n-heptanol
|
| Vigon International |
| Alcohol C-7 (Heptanol)
|
| WholeChem |
| Heptyl alcohol
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 23 - Do not breath vapour.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Human Experience: |
| 1 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 500 mg/kg
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 35, Pg. 501, 1974.
oral-rabbit LD50 750 mg/kg
Hygiene and Sanitation Vol. 31(1-3), Pg. 310, 1966.
oral-mouse LD50 1500 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 31, Pg. 16, 1966.
unreported-mammal (species unspecified) LD50 4350 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
|
| Dermal Toxicity: |
skin-rabbit LD50 2000 mg/kg
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 35, Pg. 501, 1974.
|
| Inhalation Toxicity: |
inhalation-mouse LC50 6600 mg/m3/2H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 72, 1982.
inhalation-mammal (species unspecified) LC50 6600 mg/m3
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
|
Safety in Use Information:
| Category: | | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for 1-heptanol usage levels up to: | | | 3.0000 % in the fragrance concentrate.
|
| |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 3.00000 |
| beverages(nonalcoholic): | - | 0.90000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 1.00000 | 5.00000 |
| fruit ices: | 1.00000 | 5.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 3.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Flavouring Group Evaluation 1, Revision 1 (FGE.01Rev 1): Branched-chain aliphatic saturated aldehydes, carboxylic acids and related esters of primary alcohols and branched-chain carboxylic acids from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf
|
Flavouring Group Evaluation 2, Revision 1 (FGE.02) : Branched- and straight-chain aliphatic saturated primary alcohols and related esters of primary alcohols and straight-chain carboxylic acids and one straight-chain aldehyde from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
|
Flavouring Group Evaluation 01 Rev2 (FGE.01 Rev2): Branched-chain aliphatic saturated aldehydes, carboxylic acids and related esters of primary alcohols and branched-chain carboxylic acids from chemical groups 1 and 2
View page or View pdf
|
Scientific Opinion on the safety and efficacy of straight-chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species
View page or View pdf
|
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):111-70-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :8129 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| heptan-1-ol |
| Chemidplus:0000111706 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:111-70-6 |
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| aldehydic |
2- tridecenal
FL/FR |
| animal |
iso butyl quinoline
FR |
| brown |
sec- heptyl acetate
FL/FR |
| caramellic |
fenugreek absolute
FL/FR |
| chocolate |
2,5- dimethyl pyrazine
FL/FR |
| citrus |
neroli ketone
FR |
| dairy |
methyl butyl phenyl acetate
FL/FR |
| fatty |
decanol
FL/FR |
2- nonen-1-ol
FL/FR |
2- nonenal
FL/FR |
| floral |
allyl anthranilate
FL/FR |
cassie concrete
FR |
2,4- dimethyl-3-cyclohexene-1-methanol
FR |
geranium pyran
FR |
geranium specialty
FR |
(E)- geranyl acetone
FL/FR |
geranyl phenyl acetate
FL/FR |
neryl formate
FL/FR |
iso phytol
FL/FR |
| fruity |
iso amyl isobutyrate
FL/FR |
benzaldehyde
FL/FR |
2- hexen-1-ol
FL/FR |
(E)-2- hexen-1-ol
FL/FR |
3- nonen-2-one
FL/FR |
tropical thiazole
FL/FR |
| green |
acetaldehyde butyl phenethyl acetal
FL/FR |
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR |
acetaldehyde dipropyl acetal
FL/FR |
acetaldehyde ethyl phenethyl acetal
FL/FR |
bromstyrol
CS |
3,5,6-neo cyclocitral
FR |
para- dimethyl hydroquinone
FL/FR |
diphenyl oxide
FL/FR |
galbanum oil terpeneless
FL/FR |
galbanum oleoresin
FL/FR |
(Z)-4- heptenal
FL/FR |
heptyl acetate
FL/FR |
heptyl cinnamate
FL/FR |
(Z)-2- hexen-1-ol
FL/FR |
(Z)-3- hexen-1-yl (E)-crotonate
FL/FR |
(Z)-3- hexen-1-yl (Z)-3-hexenoate
FL/FR |
(E)-2- hexen-1-yl acetate
FL/FR |
(Z)-3- hexen-1-yl benzoate
FL/FR |
(Z)-3- hexen-1-yl lactate
FL/FR |
(Z)-3- hexen-1-yl methyl carbonate
FL/FR |
3- hexenal
FL/FR |
4- hexenol
FL/FR |
hexoxyacetaldehyde dimethyl acetal
FR |
hexyl heptanoate
FL/FR |
hexyl hexanoate
FL/FR |
lawsonia inermis leaf oil CO2 extract
FR |
(Z)- leaf acetal
FL/FR |
leafy oxime
FR |
methyl heptine carbonate
FL/FR |
methyl octine carbonate
FL/FR |
methyl octine carbonate replacer
FR |
3,6- nonadien-1-ol
FL/FR |
(E,Z)-2,6- nonadien-1-ol
FL/FR |
(E,Z)-2,6- nonadien-1-yl acetate
FL/FR |
(Z)-2- nonen-1-ol
FL/FR |
(E)-2- nonen-1-ol
FL/FR |
2- nonyn-1-al dimethyl acetal
FR |
2- octen-1-ol
FL/FR |
(E)-2- octen-1-yl acetate
FL/FR |
(Z)-5- octen-1-yl propionate
FL/FR |
olive oil absolute
FL/FR |
1- penten-3-ol
FL/FR |
3- phenyl propionaldehyde
FL/FR |
iso propyl phenyl propionaldehyde
FR |
rosa damascena leaf absolute
FR |
rosacyanthin
FR |
rose leaf absolute (rosa centifolia)
FL/FR |
styralyl acetate
FL/FR |
violet dienyne
FR |
violet leaf oil (viola odorata)
FL/FR |
violet nitrile
FR |
| herbal |
6- acetoxydihydrotheaspirane
FL/FR |
alpha- amyl cinnamyl formate
FL/FR |
anethum graveolens herb oil
FL/FR |
anthemis nobilis flower oil roman
FL/FR |
sweet basil absolute
FL/FR |
(+)-alpha- campholenic aldehyde
FL/FR |
dimethyl benzyl carbinyl formate
FL/FR |
herbal heptane
FR |
hop absolute
FL/FR |
hop oil
FL/FR |
linalyl octanoate
FL/FR |
lovage tincture
FL/FR |
theaspirane
FL/FR |
tricyclodecyl acetate
FR |
| melon |
(Z)-6- nonen-1-ol
FL/FR |
(Z)-6- nonen-1-yl acetate
FL/FR |
| minty |
iso propyl tiglate
FL/FR |
iso pulegyl formate
FL/FR |
| mossy |
treemoss absolute
FR |
| pine |
dipentene terpene hydrocarbon byproducts
FR |
| spicy |
iso butyl angelate
FL/FR |
(-)- cubenol
FL/FR |
iso cyclogeraniol (IFF)
FR |
| sulfurous |
grapefruit menthane
FL/FR |
3-( methyl thio) hexanol
FL/FR |
| For Flavor |
| No flavor group found for these |
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR |
6- acetoxydihydrotheaspirane
FL/FR |
2- acetyl-4-isopropyl pyridine
FL |
allyl anthranilate
FL/FR |
alpha- amyl cinnamyl formate
FL/FR |
dimethyl benzyl carbinyl formate
FL/FR |
2- ethyl-4,5-dimethyl oxazole
FL |
heptyl cinnamate
FL/FR |
(Z)-3- hexen-1-yl (E)-crotonate
FL/FR |
(E)-4- hexenal
FL |
hexyl heptanoate
FL/FR |
2- methyl thiazole
FL |
4-( methyl thio) butanol
FL |
2- methyl-3-heptanone
FL |
3- methyl-3-pentanol
FL |
1,5- octadien-3-ol
FL |
2-iso propyl-3-(methyl thio) pyrazine
FL |
iso pulegyl formate
FL/FR |
| aldehydic |
| aldehydic |
2- tridecenal
FL/FR |
| alliaceous |
3- tetrahydrothiophenone
FL |
tropical thiazole
FL/FR |
| apple |
(E,Z)-2,6- nonadien-1-ol
FL/FR |
| caramellic |
fenugreek absolute
FL/FR |
| cooling |
theaspirane
FL/FR |
| dairy |
methyl butyl phenyl acetate
FL/FR |
| fatty |
(E,E)-2,4- heptadienal
FL |
sec- heptyl acetate
FL/FR |
(Z)-3- hexen-1-yl benzoate
FL/FR |
(Z)-2- nonen-1-ol
FL/FR |
2- nonen-1-ol
FL/FR |
2- nonenal
FL/FR |
2- octen-1-ol
FL/FR |
| floral |
(E)- geranyl acetone
FL/FR |
geranyl phenyl acetate
FL/FR |
| fruity |
iso amyl isobutyrate
FL/FR |
benzaldehyde
FL/FR |
2- hexen-1-ol
FL/FR |
hexyl hexanoate
FL/FR |
linalyl octanoate
FL/FR |
neryl formate
FL/FR |
styralyl acetate
FL/FR |
| green |
acetaldehyde butyl phenethyl acetal
FL/FR |
acetaldehyde dipropyl acetal
FL/FR |
acetaldehyde ethyl phenethyl acetal
FL/FR |
iso butyl angelate
FL/FR |
(+)-alpha- campholenic aldehyde
FL/FR |
cucumber distillates
FL |
dihydroxyacetophenone (mixed isomers)
FL |
para- dimethyl hydroquinone
FL/FR |
diphenyl oxide
FL/FR |
galbanum oil terpeneless
FL/FR |
galbanum oleoresin
FL/FR |
(E)-2- heptenal
FL |
(Z)-4- heptenal
FL/FR |
heptyl acetate
FL/FR |
(Z)-2- hexen-1-ol
FL/FR |
(E)-2- hexen-1-ol
FL/FR |
(Z)-3- hexen-1-yl (Z)-3-hexenoate
FL/FR |
(E)-2- hexen-1-yl acetate
FL/FR |
(Z)-3- hexen-1-yl lactate
FL/FR |
(Z)-3- hexen-1-yl methyl carbonate
FL/FR |
3- hexenal
FL/FR |
(Z)- leaf acetal
FL/FR |
3,5- lutidine
FL |
methyl heptine carbonate
FL/FR |
methyl octine carbonate
FL/FR |
3-(5- methyl-2-furyl) butanal
FL |
3,6- nonadien-1-ol
FL/FR |
(E,Z)-2,6- nonadien-1-yl acetate
FL/FR |
(E)-2- nonen-1-ol
FL/FR |
(Z)-6- nonen-1-yl acetate
FL/FR |
(E)-2- octen-1-yl acetate
FL/FR |
(Z)-5- octen-1-yl propionate
FL/FR |
1- penten-3-ol
FL/FR |
3- phenyl propionaldehyde
FL/FR |
2- propyl pyrazine
FL |
iso propyl tiglate
FL/FR |
propylene glycol acetone ketal
FL |
rose leaf absolute (rosa centifolia)
FL/FR |
violet leaf oil (viola odorata)
FL/FR |
| herbal |
anethum graveolens herb oil
FL/FR |
anthemis nobilis flower oil roman
FL/FR |
sweet basil absolute
FL/FR |
hop absolute
FL/FR |
hop oil
FL/FR |
lovage tincture
FL/FR |
| metallic |
4- hexenol
FL/FR |
3-( methyl thio) hexanol
FL/FR |
| musty |
2,5- dimethyl pyrazine
FL/FR |
| nutty |
arachis hypogaea fruit extract
FL |
| oily |
3- nonen-2-one
FL/FR |
olive oil absolute
FL/FR |
iso phytol
FL/FR |
| onion |
propyl thioacetate
FL |
| spicy |
(-)- cubenol
FL/FR |
| sulfurous |
grapefruit menthane
FL/FR |
| waxy |
decanol
FL/FR |
(Z)-6- nonen-1-ol
FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | alcohol C-7 | | | alcohol C-7 FCC | | | alcohol C-7 natural | | | alcohol, heptyl, 1- | | | enanthic alcohol | | | enanthyl alcohol | | | gentanol | | | heptan-1-ol | | N- | heptan-1-ol | | N- | heptanol | | | heptanol-1 FCC | | | heptyl alcohol | | N- | heptyl alcohol | | | heptyl alcohol natural | | | hexyl carbinol | | | hydroxy heptane | | | hydroxyheptane | | 1- | hydroxyheptane |
Articles:
| PubMed:Characterization of a new mobility separation tool: HRIMS as differential mobility analyzer. |
| PubMed:Comparison between solid phase microextraction (SPME) and hollow fiber liquid phase microextraction (HFLPME) for determination of extractables from post-consumer recycled PET into food simulants. |
| PubMed:Electro-driven extraction of inorganic anions from water samples and water miscible organic solvents and analysis by ion chromatography. |
| PubMed:A laboratory evaluation of alcohols as attractants for the sandfly Lutzomyia longipalpis (Diptera:Psychodidae). |
| PubMed:Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats. |
| PubMed:Optimization of two different dispersive liquid-liquid microextraction methods followed by gas chromatography-mass spectrometry determination for polycyclic aromatic hydrocarbons (PAHs) analysis in water. |
| PubMed:Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. |
| PubMed:Role of gap junction-mediated communications in regulating large-scale chromatin configuration remodeling and embryonic developmental competence acquisition in fully grown bovine oocyte. |
| PubMed:Simultaneous derivatization and extraction of chlorophenols in water samples with up-and-down shaker-assisted dispersive liquid-liquid microextraction coupled with gas chromatography/mass spectrometric detection. |
| PubMed:Attractant and disruptant semiochemicals for Dendroctonus jeffreyi (Coleoptera: Curculionidae: Scolytinae). |
| PubMed:Two-phase electromembrane extraction followed by gas chromatography-mass spectrometry analysis. |
| PubMed:Identification of characteristic flavour precursors from enzymatic hydrolysis-mild thermal oxidation tallow by descriptive sensory analysis and gas chromatography-olfactometry and partial least squares regression. |
| PubMed:Growth differentiation factor 5 modulation of chondrogenesis of self-assembled constructs involves gap junction-mediated intercellular communication. |
| PubMed:Fabrication of novel nanoporous array anodic alumina solid-phase microextraction fiber coating and its potential application for headspace sampling of biological volatile organic compounds. |
| PubMed:Change of volatile compounds in fresh fish meat during ice storage. |
| PubMed:A synthetic recursive "+1" pathway for carbon chain elongation. |
| PubMed:Trace determination of perchlorate using electromembrane extraction and capillary electrophoresis with capacitively coupled contactless conductivity detection. |
| PubMed:Noninvasive evaluation of contractile behavior of cardiomyocyte monolayers based on motion vector analysis. |
| PubMed:Laboratory investigation on the role of organics in atmospheric nanoparticle growth. |
| PubMed:Simple models for the effect of aliphatic alcohol additives on the retention in reversed-phase liquid chromatography. |
| PubMed:Development of a modified grating coupler in application to geosciences. |
| PubMed:Inhibition of electrochemically controlled bioluminescence of bacterial luciferase by n-alkyl alcohols. |
| PubMed:Patterned cardiomyocytes on microelectrode arrays as a functional, high information content drug screening platform. |
| PubMed:Water structure and dynamics at a silica surface: Pake doublets in 1H NMR spectra. |
| PubMed:NOS inhibition synchronizes calcium oscillations in human adipose tissue-derived mesenchymal stem cells by increasing gap-junctional coupling. |
| PubMed:Assay for molecular transport across gap junction channels in one-dimensional cell arrays. |
| PubMed:[Effects of gap junction blocking on the oxygen partial pressure in acupoints of the bladder meridian]. |
| PubMed:Retention prediction in reversed-phase liquid chromatography systems with methanol/water mobile phases containing different alkanols as additives. |
| PubMed:Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols. |
| PubMed:Aromatic potential of botrytized white wine grapes: identification and quantification of new cysteine-S-conjugate flavor precursors. |
| PubMed:Behavioral and electrophysiological responses of Triatoma brasiliensis males to volatiles produced in the metasternal glands of females. |
| PubMed:Effect of the thermodynamic properties of W/O microemulsions on samarium oxide nanoparticle size. |
| PubMed:Damaging effect of cumulus denudation on rabbit oocytes. |
| PubMed:Aroma-active components of Lycii fructus (kukija). |
| PubMed:Volatile compounds in dry-cured Serrano ham subjected to high pressure processing. Effect of the packaging material. |
| PubMed:Solubilization in alkanes by alcohols as reverse hydrotropes or "lipotropes". |
| PubMed:Paracrine factors from cumulus-enclosed oocytes ensure the successful maturation and fertilization in vitro of denuded oocytes in the cat model. |
| PubMed:In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes. |
| PubMed:Heterologous expression of the alcohol dehydrogenase (adhI) gene from Geobacillus thermoglucosidasius strain M10EXG. |
| PubMed:Novel fluoroalkyl end-capped amphiphilic diblock copolymers with pH/temperature response and self-assembly behavior. |
| PubMed:Fabrication and characterization of cross-linkable hydrogel particles based on hyaluronic acid: potential application in vocal fold regeneration. |
| PubMed:Application of a new theoretical procedure for calculating Kirkwood correlation factors in alkanol + hexane and alkanol + pentane mixtures. |
| PubMed:Mice lacking NKCC1 have normal olfactory sensitivity. |
| PubMed:Miscibility and interaction between 1-alkanol and short-chain phosphocholine in the adsorbed film and micelles. |
| PubMed:Molecular interactions in alcohol-ethyl methacrylate mixtures. |
| PubMed:Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation. |
| PubMed:Stimulation of corneal epithelial migration by a synthetic peptide (PHSRN) corresponding to the second cell-binding site of fibronectin. |
| PubMed:Electrokinetic migration of acidic drugs across a supported liquid membrane. |
| PubMed:Fluorescent detection for cyclic and acyclic alcohol guests by naphthalene-appended amino-beta-cyclodextrins. |
| PubMed:Kinetic model for reactivity in quaternary water-in-oil microemulsions. |
| PubMed:Effect of heptanol on noradrenaline-induced contractions in rat vas deferens. |
| PubMed:In vitro effects of insulin-like growth factors and insulin on oocyte maturation and maturation-inducing steroid production in ovarian follicles of common carp, Cyprinus carpio. |
| PubMed:[The effect of gap blocker 1-heptanol on function and morphology of guinea pig cochlea]. |
| PubMed:Heat capacity studies of formation of micelle-like structure in aqueous solutions of some alkane polyols. |
| PubMed:Improved vacuum-UV (VUV)-initiated photomineralization of organic compounds in water with a xenon excimer flow-through photoreactor (Xe2* lamp, 172 nm) containing an axially centered ceramic oxygenator. |
| PubMed:Biocompatibility of a nonpenetrating synthetic cornea in vascularized rabbit corneas. |
| PubMed:The potential role of gap junction communication between cumulus cells and bovine oocytes during in vitro maturation. |
| PubMed:Aroma analysis of light-exposed milk stored with and without natural and synthetic antioxidants. |
| PubMed:Insulin-like growth factor-I induces oocyte maturational competence but not meiotic resumption in white bass (Morone chrysops) follicles in vitro: evidence for rapid evolution of insulin-like growth factor action. |
| PubMed:Comparison of the olfactory sensitivity of two sympatric steppe grasshopper species (Orthoptera: Acrididae) to plant volatile compounds. |
| PubMed:Junctional and nonjunctional effects of heptanol and glycyrrhetinic acid derivates in rat mesenteric small arteries. |
| PubMed:The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha. |
| PubMed:Effect of alcohol addition to the aqueous phase on the thermal effects of micellization of cationic benzyldimethyldodecylammonium bromide and its adsorption onto porous and nonporous silicas. |
| PubMed:General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels. |
| PubMed:Electron microprobe analysis of ouabain-exposed ciliary epithelium: PE-NPE cell couplets form the functional units. |
| PubMed:Total synthesis of (+/-)-didehydrostemofoline (asparagamine A) and (+/-)-isodidehydrostemofoline. |
| PubMed:An investigation of chemotaxis in the insect parasitic nematode Heterorhabditis bacteriophora. |
| PubMed:Study of light-induced volatile compounds in goat's milk cheese. |
| PubMed:Disposition of short-chain aliphatic alcohols in rabbit vitreous by ocular microdialysis. |
| PubMed:Activation and inhibition of the transduction process in silkmoth olfactory receptor neurons. |
| PubMed:Solvent effect on ion-pair extraction of 2-(2-pyridylazo)-1-naphthol-4-sulfonate anion with solvated hydroxonium ion using alcohols and 1-octanol/octane mixed solvents. |
| PubMed:Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose. |
| PubMed:A comparison of lipase-catalysed ester and lactone synthesis in low-water systems: analysis of optimum water activity. |
| PubMed:Growth factors but not gap junctions play a role in injury-induced Ca2+ waves in epithelial cells. |
| PubMed:Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition. |
| PubMed:Dual functions for connexins: Cx43 regulates growth independently of gap junction formation. |
| PubMed:Gap junction blockers decrease defibrillation thresholds without changes in ventricular refractoriness in isolated rabbit hearts. |
| PubMed:Involvement of connexin 43 in meiotic maturation of bovine oocytes. |
| PubMed:Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? |
| PubMed:Straight-chain alcohols exhibit a cutoff in potency for the inhibition of recombinant glutamate receptor subunits. |
| PubMed:In vitro hormone induction of final oocyte maturation in striped bass (Morone saxatilis) follicles is inhibited by blockers of phosphatidylinositol 3-kinase activity. |
| PubMed:Sequential substitution of 1,2-dichloro-ethene: a convenient stereoselective route to (9Z,11E)-, (10E,12Z)- and (10Z,12Z)-. |
| PubMed:Bacterial expression, purification, and characterization of rat hydroxysteroid sulfotransferase STa. |
| PubMed:Effect of beta-galactosidase hydration on alcoholysis reaction in organic one-phase liquid systems. |
| PubMed:Effects of insulin-like growth factor-I on in vitro final oocyte maturation and ovarian steroidogenesis in striped bass, Morone saxatilis. |
| PubMed:New syntheses of the rice moth and stink bug pheromones by employing (2R, 6S)-7-acetoxy-2,6-dimethyl-1-heptanol as a building block. |
| PubMed:Alcoholysis and reverse hydrolysis reactions in organic one-phase system with a hyperthermophilic beta-glycosidase. |
| PubMed:Mechanical strain-induced Ca(2+) waves are propagated via ATP release and purinergic receptor activation. |
| PubMed:Large-scale preparation of (9Z,12E)-[1-(13)C]-octadeca-9,12-dienoic acid, (9Z,12Z,15E)-[1-(13)C]-octadeca-9,12,15-trienoic acid and their [1-(13)C] all-cis isomers. |
| PubMed:Analysis of synaptic quantal depolarizations in smooth muscle using the wavelet transform. |
| PubMed:Intramolecular charge transfer at reverse micelle-water pool interface: p-N,N-dimethylaminobenzoic acid in AOT/cyclohexane/water reverse micelle. |
| PubMed:Use of partition models in setting health guidelines for volatile organic compounds. |
| PubMed:Characterization of nitric oxide- and prostaglandin-independent relaxation in response to acetylcholine in rabbit renal artery. |
| PubMed:An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma. |
| PubMed:Heptanol exerts epileptiform effects in identified neurons of the buccal ganglia of Helix pomatia. |
| PubMed:Effects of short chain alkanols on the inducible nitric oxide synthase in a glial cell line. |
| PubMed:Effects of heptanol on the neurogenic and myogenic contractions of the guinea-pig vas deferens. |
| PubMed:Effects of transforming growth factor-beta 2, interleukin 6 and fibronectin on corneal epithelial wound healing. |
| PubMed:Agrobacterium tumefaciens beta-glucosidase is also an effective beta-xylosidase, and has a high transglycosylation activity in the presence of alcohols. |
| PubMed:Studies on the interactions of chiral secondary alcohols with rat hydroxysteroid sulfotransferase STa. |
| PubMed:Combined effects of substance P and insulin-like growth factor-1 on corneal epithelial wound closure of rabbit in vivo. |
| PubMed:Correlation between hydrophobicity of short-chain aliphatic alcohols and their ability to alter plasma membrane integrity. |
| PubMed:Modulation of GABAA receptor function by alcohols: effects of subunit composition and differential effects of ethanol. |
| PubMed:Human granulosa cells in culture exhibit functional cyclic AMP-regulated gap junctions. |
| PubMed:Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery. |
| PubMed:The metabolism of n-nonane in male Fischer 344 rats. |
| PubMed:Mitochondrial alcohol dehydrogenase from ethanol-grown Euglena gracilis. |
| PubMed:Probing a functional role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase through transesterification reactions in organic solvent. |
| PubMed:Channel inhibition by alkanols occurs at a binding site on the nicotinic acetylcholine receptor. |
| PubMed:The role of myoendothelial cell contact in non-nitric oxide-, non-prostanoid-mediated endothelium-dependent relaxation of porcine coronary artery. |
| PubMed:Lethality, teratogenicity and growth inhibition of heptanol in Xenopus assayed by a modified frog embryo teratogenesis assay-Xenopus (FETAX) procedure. |
| PubMed:Volatile organic chemicals of a shore-dwelling cyanobacterial mat community. |
| PubMed:Lipases from Rhizomucor miehei and Humicola lanuginosa: modification of the lid covering the active site alters enantioselectivity. |
| PubMed:Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells. |
| PubMed:Heptanol-induced decrease in cardiac gap junctional conductance is mediated by a decrease in the fluidity of membranous cholesterol-rich domains. |
| PubMed:Inhibitory effects of n-alkanols on the hormonal induction of maturation in follicle-enclosed Xenopus oocytes: implications for gap junctional transport of maturation-inducing steroid. |
| PubMed:Interleukin 6 facilitates corneal epithelial wound closure in vivo. |
| PubMed:Cytoplasmic dye transfer between metastatic tumor cells and vascular endothelium. |
| PubMed:Host-derived volatiles as attractants and pheromone synergists for driedfruit beetleCarpophilus hemipterus. |
| PubMed:Reversed-phase liquid chromatographic determination of idarubicin and its 13-hydroxy metabolite in human plasma. |
| PubMed:Adaptation of the membrane fatty acid composition by growth in the presence of n-alkanols influences glycosyltransferase expression in Streptococcus salivarius. |
| PubMed:Streptococcus pneumoniae type XIV polysaccharide: synthesis of a repeating branched tetrasaccharide with dioxa-type spacer-arms. |
| PubMed:Quantitative gap junction alterations in mammalian heart cells quickly frozen or chemically fixed after electrical uncoupling. |
| PubMed:Screening for eye irritancy using cultured HeLa cells. |
| PubMed:High-performance liquid chromatographic method for pharmacokinetic studies on the new anthracycline 4-demethoxydaunorubicin and its 13-dihydro derivative. |
| PubMed:Effect of several uncouplers of cell-to-cell communication on gap junction morphology in mammalian heart. |
| PubMed:Extraction chromatography with macroreticular polymer beads impregnated with monothiodibenzoylmethane solution. |
| PubMed:Partial molar volumes of some 1-alkanols in erythrocyte ghosts and lipid bilayers. |
| PubMed:Determination of odour affinities based on the dose-response relationships of the frog's electro-olfactogram. |
| PubMed:Liquid chromatographic determination of tetracycline in plasma and urine. |
| PubMed:Reversed-phase liquid chromatographic determination of plasma levels of adriamycin and adriamycinol. |
| PubMed:Liquid chromatographic determination of daunorubicin and daunorubicinol in plasma from leukemic patients. |
| PubMed:Relative rates of hydrolysis by rat pancreatic lipase of esters of C2-C18 fatty acids with C1-C18 primary n-alcohols. |
|
3D/inchi