Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
Odor Type: sulfurous |
sulfurous fatty roasted meaty vegetable |
Odor Description:at 0.10 % in propylene glycol. sulfurous fatty roasted meaty vegetable |
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 11 - Highly flammable. R 20/22 - Harmful by inhalation and if swallowed. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
|
Dermal Toxicity: |
subcutaneous-mouse LD50 > 100 mg/kg Nature. Vol. 174, Pg. 737, 1954.
|
Inhalation Toxicity: |
inhalation-rat TCLo 2000 ppm/4H Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 343, 1949.
|
Safety in Use Information:
Category: | flavoring agents |
Recommendation for amyl mercaptan usage levels up to: | | not for fragrance use.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.12 (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 78 (μg/person/day) |
NOEL (No Observed Effect Level): | 0.56 (mg/kg bw per day) |
Threshold of Concern: | 1800 (μg/person/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 23 |
Click here to view publication 23 |
| average usual ppm | average maximum ppm |
baked goods: | 0.06000 | 0.50000 |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | 0.01000 | 0.05000 |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | 0.10000 | 0.50000 |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | 0.05000 | 0.50000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | 0.10000 | 0.50000 |
milk products: | 0.10000 | 0.50000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | 0.40000 | 2.00000 |
snack foods: | - | - |
soft candy: | - | - |
soups: | 0.10000 | 0.50000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
|
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 0.20000 | 1.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 0.10000 | 0.50000 |
Edible ices, including sherbet and sorbet (03.0): | 0.20000 | 1.00000 |
Processed fruit (04.1): | 0.20000 | 1.00000 |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
Confectionery (05.0): | 0.20000 | 1.00000 |
Chewing gum (05.3): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 0.10000 | 0.50000 |
Bakery wares (07.0): | 0.20000 | 1.00000 |
Meat and meat products, including poultry and game (08.0): | 0.10000 | 0.20000 |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.10000 | 0.20000 |
Eggs and egg products (10.0): | - | - |
Sweeteners, including honey (11.0): | - | - |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 0.10000 | 0.50000 |
Foodstuffs intended for particular nutritional uses (13.0): | 0.20000 | 1.00000 |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 0.10000 | 0.30000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 0.20000 | 1.00000 |
Ready-to-eat savouries (15.0): | 0.40000 | 2.00000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.10000 | 0.50000 |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
|
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf
|
Flavouring Group Evaluation 74 (FGE.74)[1]: Consideration of Simple Aliphatic Sulphides and Thiols evaluated by JECFA (61st meeting) Structurally related to Aliphatic and Alicyclic Mono-, Di-, Tri-, and Polysulphides with or without Additional Oxygenated Functional Groups from Chemical Group 20 evaluated by EFSA in FGE.08 (2008) View page or View pdf
|
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf
|
Flavouring Group Evaluation 91 (FGE.91): Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by EFSA in FGE.08Rev1 (2009) View page or View pdf
|
Flavouring Group Evaluation 08 Rev2 (FGE.08 Rev2): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 08, Revision 5 (FGE.08Rev5): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf
|
EPI System: View |
NIOSH International Chemical Safety Cards:search |
NIOSH Pocket Guide:search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):110-66-7 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :8067 |
National Institute of Allergy and Infectious Diseases:Data |
WISER:UN 1111 |
WGK Germany:3 |
pentane-1-thiol |
Chemidplus:0000110667 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:110-66-7 |
References:
Other Information:
Potential Blenders and core components note
For Odor |
alliaceous |
dimethyl trisulfide FL/FR |
dipropyl disulfide FL/FR |
ferula assa-foetida gum oil FL/FR |
methyl furfuryl disulfide FL/FR |
propyl mercaptan FL/FR |
burnt |
rum ether FL/FR |
chocolate |
2,6- dimethyl pyrazine FL/FR |
citrus |
grapefruit mercaptan FL/FR |
coffee |
coffee difuran FL/FR |
2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR |
earthy |
nutty pyrazine FL/FR |
ethereal |
2- methyl-1-butanol FL/FR |
fermented |
ethyl crotonate FL/FR |
fruity |
tropical thiazole FL/FR |
tropical trithiane FL/FR |
green |
2- heptyl furan FL/FR |
(E,Z)-2,6- nonadienal FL/FR |
meaty |
meaty dithiane FL/FR |
4- methyl nonanoic acid FL/FR |
sulfurol FL/FR |
sulfuryl acetate FL/FR |
moldy |
strawberry furanone methyl ether FL/FR |
musty |
hazelnut pyrazine FL/FR |
nutty |
4,5- dimethyl-2-ethyl-3-thiazoline FL/FR |
2- ethyl pyrazine FL/FR |
2- ethyl-4-methyl thiazole FL/FR |
2- methyl pyrazine FL/FR |
2- methyl-3-(methyl thio) pyrazine FL/FR |
phenolic |
2,3- dimethyl benzofuran FL/FR |
ortho- guaiacol FL/FR |
4- vinyl phenol FL/FR |
smoky |
pyroligneous acids FL/FR |
sulfurous |
benzothiazole FL/FR |
dimethyl disulfide FL/FR |
dimethyl sulfide FL/FR |
ethyl 2-mercaptopropionate FL/FR |
ethyl 3-mercaptopropionate FL/FR |
ferula assa-foetida absolute FL/FR |
fish thiol FL/FR |
2- mercaptopropionic acid FL/FR |
methyl 3-(methyl thio) propionate FL/FR |
4- methyl 4-mercaptopentan-2-one 1% solution FL/FR |
2- methyl 5-(methyl thio) furan FL/FR |
3-( methyl thio) hexanol FL/FR |
2-( methyl thio) phenol FL/FR |
onion oil FL/FR |
1- phenethyl mercaptan FL/FR |
tobacco |
methyl benzoxole FL/FR |
For Flavor |
No flavor group found for these |
4- acetyl-2-methyl pyrimidine FL |
allyl methyl disulfide FL |
allyl methyl trisulfide FL |
allyl propyl disulfide FL |
allyl propyl sulfide FL |
allyl propyl trisulfide FL |
gamma- aminobutyric acid FL |
iso amyl mercaptan FL |
1,2- butane dithiol FL |
2-(2- butyl)-4,5-dimethyl-3-thiazoline FL |
cyclopropyl (E,Z)-2,6-nonadienamide FL |
2,5- diethyl thiazole FL |
diethyl trisulfide FL |
dihydro-2,4,6-trimethyl-1,3,5(4H)-dithiazine FL |
dimethyl tetrasulfide FL |
2,6- dimethyl-3-((2-methyl-3-furyl)thio)-4-heptanone FL |
bis(2,5- dimethyl-3-furyl) disulfide FL |
(Z+E)-2,5- dimethyl-3-tetrahydrofuran thiol FL |
(Z+E)-2,5- dimethyl-3-thioacetoxytetrahydrofuran FL |
2,5- dimethyl-3-thiofuroyl furan FL |
dipropyl sulfide FL |
ethyl (E,Z)-2,6-nonadienamide FL |
S- ethyl 2-acetyl aminoethane thioate FL |
ethyl 3-mercaptopropionate FL/FR |
ethyl 4-(acetyl thio) butyrate FL |
ethyl methyl trisulfide FL |
ethyl propyl disulfide FL |
ethyl propyl trisulfide FL |
2- ethyl-3-methyl thiopyrazine FL |
(Z+E)-5- ethyl-4-methyl-2-(2-butyl) thiazoline FL |
(Z+E)-5- ethyl-4-methyl-2-(2-methyl propyl) thiazoline FL |
heptyl mercaptan FL |
2- hexyl thiophene FL |
1-(3- hydroxy-5-methyl-2-thienyl) ethanone FL |
3- mercapto-3-methyl butyl formate FL |
4- mercapto-3-methyl-2-butanol FL |
4- methyl 4-mercaptopentan-2-one 1% solution FL/FR |
methyl dihydrofuran thiol FL |
2- methyl thiazolidine FL |
2-( methyl thio) ethanol FL |
2-( methyl thio) methyl-2-butenal FL |
2- methyl-1-butane thiol FL |
4- methyl-2-(methyl thiomethyl)-2-hexenal FL |
2- methyl-2-thiazoline FL |
2- methyl-3-,5 or 6-(furfuryl thio) pyrazine FL/FR |
2- methyl-3-(methyl thio) pyrazine FL/FR |
2- methyl-3-furyl tetrasulfide FL |
3-((2- methyl-3-furyl)thio)-4-heptanone FL |
4-((2- methyl-3-furyl)thio)-5-nonanone FL |
1,9- nonane dithiol FL |
peanut dithiazine FL |
1- phenethyl mercaptan FL/FR |
1,3- propane dithiol FL |
propenyl propyl disulfide FL |
iso propyl disulfide FL |
2- propyl pyridine FL |
2-iso propyl-3-(methyl thio) pyrazine FL |
thiazole FL |
3- thienyl mercaptan FL |
thioacetic acid FL |
2,3,5- trithiahexane FL |
|
3,5- diisopropyl-1,2,4-trithiolane FL |
N-(2-(3,4- dimethoxyphenyl)ethyl)-3,4-dimethoxycinnamic acid amide FL |
3,5- dimethyl-1,2,4-trithiolane FL |
3,7- dimethyl-2,6-octadien-1-yl cyclopropyl carboxamide FL |
2,4- dimethyl-3-oxazoline FL |
4- mercapto-2-pentanone 1% in acetoin FL |
(±)-3-( methyl thio) heptanal FL |
2- methyl-1-methyl thio-2-butene FL |
pyrrolidino-(1,2E)-4H-2,4-dimethyl-1,3,5-dithiazine FL |
1-(2- thienyl) butanone FL |
alliaceous |
alliaceous |
allyl disulfide FL |
allyl mercaptan FL |
allyl thiopropionate FL |
benzyl mercaptan FL |
1,3- butane dithiol FL |
cyclopentyl mercaptan FL |
dicyclohexyl disulfide FL |
diethyl disulfide FL |
dimethyl trisulfide FL/FR |
dipropyl disulfide FL/FR |
dipropyl trisulfide FL |
ferula assa-foetida gum oil FL/FR |
3- mercapto-2-methyl pentanol FL |
3- mercapto-2-pentanone FL |
methyl 3-mercaptobutanoate FL |
2- methyl thioacetaldehyde FL |
propyl mercaptan FL/FR |
3- tetrahydrothiophenone FL |
tropical thiazole FL/FR |
burnt |
bacon dithiazine FL |
1,6- hexane dithiol FL |
rum ether FL/FR |
cabbage |
methyl 2-thiofuroate FL |
chemical |
2,3- dimethyl benzofuran FL/FR |
2,5- dimethyl furan FL |
citrus |
grapefruit mercaptan FL/FR |
cocoa |
butyraldehyde FL |
coffee |
coffee difuran FL/FR |
2- ethyl-4-methyl thiazole FL/FR |
methyl furfuryl disulfide FL/FR |
corn chip |
2- acetyl-2-thiazoline FL |
earthy |
difurfuryl sulfide FL |
1,8- octane dithiol FL |
eggy |
iso propyl mercaptan FL |
ethereal |
2- methyl-1-butanol FL/FR |
fatty |
(E,E)-2,4- decadienal FL |
2- heptyl furan FL/FR |
4- methyl nonanoic acid FL/FR |
2- pentyl thiophene FL |
fruity |
2- ethyl-2,5-dihydro-4-methyl thiazole FL |
tropical trithiane FL/FR |
garlic |
allyl methyl sulfide FL |
garlic oleoresin FL |
green |
4- methyl thiazole FL |
(E,Z)-2,6- nonadienal FL/FR |
4- penten-1-yl acetate FL |
herbal |
massoia bark oil FL |
meaty |
4- allyl-2,6-dimethoxyphenol FL |
benzothiazole FL/FR |
2,6- dimethyl pyrazine FL/FR |
2,6- dimethyl thiophenol FL |
2,5- dimethyl-3-furan thiol FL |
1,1- ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4% FL |
furfuryl 2-methyl-3-furyl disulfide FL |
4- furfuryl thio-2-pentanone FL |
meaty dithiane FL/FR |
3- mercapto-2-butanone FL |
(R,S)-2- mercapto-3-butanol FL |
2- mercaptomethyl pyrazine FL |
2- mercaptopropionic acid FL/FR |
2- methyl 3-(methyl thio) furan FL |
2-( methyl thio) phenol FL/FR |
methyl thiofuryl butanal FL |
12- methyl tridecanal FL |
bis(2- methyl-3-furyl) disulfide FL |
S-(2- methyl-3-furyl) ethane thioate FL |
2- methyl-3-tetrahydrofuran thiol FL |
2- methyl-3-thioacetoxytetrahydrofuran FL |
phenyl mercaptan FL |
propyl 2-mercaptopropionate FL |
propyl 2-methyl-3-furyl disulfide FL |
pyrazinyl ethane thiol FL |
2- pyridinyl methane thiol FL |
sulfurol FL/FR |
sulfuryl acetate FL/FR |
thialdine FL |
ortho- thiocresol FL |
ortho- thioguaiacol FL |
metallic |
2,5- dihydroxy-1,4-dithiane FL |
3-( methyl thio) hexanol FL/FR |
moldy |
strawberry furanone methyl ether FL/FR |
musty |
2- ethoxythiazole FL |
hazelnut pyrazine FL/FR |
2- methyl 5-(methyl thio) furan FL/FR |
nutty |
3- acetyl-2,5-dimethyl thiophene FL |
2- acetyl-4-methyl thiazole FL |
arachis hypogaea fruit extract FL |
3,5- diethyl-2-methyl pyrazine FL |
2,5- diethyl-3-methyl pyrazine FL |
4,5- dimethyl-2-ethyl-3-thiazoline FL/FR |
2- ethyl pyrazine FL/FR |
methyl benzoxole FL/FR |
2- methyl pyrazine FL/FR |
nutty pyrazine FL/FR |
nutty thiazole FL |
onion |
ethyl 2-mercaptopropionate FL/FR |
furfuryl isopropyl sulfide FL |
methionol FL |
methyl propyl disulfide FL |
methyl propyl trisulfide FL |
propyl thioacetate FL |
phenolic |
2- ethyl benzene thiol FL |
4- vinyl phenol FL/FR |
popcorn |
2- propionyl-2-thiazoline FL |
radish |
3-( methyl thio) propyl mercaptoacetate FL |
roasted |
ethyl 3-(furfuryl thio) propionate FL |
hexyl mercaptan FL |
rummy |
ethyl crotonate FL/FR |
savory |
N-(2,4- dimethoxybenzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide FL |
N-( heptan-4-yl)benzo(D)(1,3)dioxole-5-carboxamide FL |
N1-(2- methoxy-4-methyl benzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide FL |
N1-(2- methoxy-4-methyl benzyl)-N2-2(2-(5-methyl pyridin-2-yl)ethyl) oxalamide FL |
seafood |
1,4- dithiane FL |
smoky |
prosopis juliflora wood extract FL |
pyroligneous acids FL/FR |
sulfurous |
allyl sulfide FL |
2,3- butane dithiol FL |
butyl mercaptan FL |
diallyl polysulfides FL |
diallyl tetrasulfide FL |
diallyl trisulfide FL |
dimethyl disulfide FL/FR |
dimethyl sulfide FL/FR |
ethyl methyl sulfide FL |
S- ethyl thioacetate FL |
ferula assa-foetida absolute FL/FR |
fish thiol FL/FR |
furfuryl methyl sulfide FL |
furfuryl thiopropionate FL |
3- mercapto-2-methyl pentanal FL |
methyl 2-(methyl thio) butyrate FL |
methyl 2-methyl-3-furyl disulfide FL |
methyl thiomethyl butyrate FL |
3- methyl-2-butane thiol FL |
2- naphthyl mercaptan FL |
onion oil FL/FR |
onion oleoresin FL |
roasted butanol FL |
2,4,6- trithiaheptane 10% in triacetin FL |
vegetable |
methyl 3-(methyl thio) propionate FL/FR |
tyramine FL |
wasabi |
2-( methyl thio) ethyl acetate FL |
woody |
ortho- guaiacol FL/FR |
yeasty |
faex extracts FL |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| amyl hydrosulfide | N- | amyl mercaptan | | amyl sulfhydrate | | amyl thioalcohol | N- | amylthiol | | mercaptan C5 | 1- | pentane thiol | | pentane-1-thiol | 1- | pentanethiol | 1- | pentanethiol 10% in triacetine | | pentyl mercaptan | N- | pentyl mercaptan | | pentylmercaptan | N- | pentylmercaptan | | thioamyl alcohol | N- | thioamyl alcohol |
Articles:
|