Name: | (2E,6Z)-dodeca-2,6-dienal |
CAS Number: | 21662-13-5 | 3D/inchi
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ECHA EINECS - REACH Pre-Reg: | 244-515-0 |
FDA UNII: | 6CPL2532NR |
Beilstein Number: | 4374899 |
XlogP3-AA: | 3.80 (est) |
Molecular Weight: | 180.29060000 |
Formula: | C12 H20 O |
NMR Predictor: | Predict (works with chrome, Edge or firefox) |
EFSA/JECFA Comments: |
The chemical name in the UL should be changed to Dodeca-(2E,6Z)-dienal, in accordance with the CAS nr and the most recent speci?cations on stereoisomeric composition (Documentation provided to EFSA nr.10) |
Category:flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | yellow clear liquid (est) |
Assay: | 97.50 to 100.00 sum of isomers
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.98700 to 0.99300 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.213 to 8.263
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Refractive Index: | 1.42500 to 1.43100 @ 20.00 °C.
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Boiling Point: | 130.00 to 131.00 °C. @ 5.00 mm Hg
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Boiling Point: | 115.00 °C. @ 0.10 mm Hg
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Acid Value: | 1.50 max. KOH/g
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Vapor Pressure: | 0.008000 mmHg @ 25.00 °C. (est) |
Flash Point: | 210.00 °F. TCC ( 98.89 °C. )
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logP (o/w): | 4.327 (est) |
Shelf Life: | 36.00 month(s) or longer if stored properly. |
Soluble in: |
| alcohol | | water, 11.33 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Type: fatty |
Odor Strength:low , recommend smelling in a 10.00 % solution or less |
citrus mandarin orange melon |
Odor Description:at 10.00 % in dipropylene glycol. deep citrus mandarin orange melon |
fatty green aldehydic spicy melon |
Odor Description:Fatty, green, aldehydic with a spice and melon nuance Mosciano, Gerard P&F 18, No. 3, 53, (1993) |
Flavor Type: green |
green herbal waxy aldehydic |
Taste Description: at 20.00 ppm. Green, herbal, waxy and aldehydic Mosciano, Gerard P&F 18, No. 3, 53, (1993) |
Odor and/or flavor descriptions from others (if found). |
Bedoukian Research |
e,z-2,6-DODECADIEN-1-AL ≥90.0% (trans,cis), Kosher |
Odor Description:A fatty, green, aldehydic character with spice, melon undertones Powerful. Blends well with citrus and florals to add freshness and watery notes. |
Taste Description:green Has application in watermelon, parsley and mushroom flavors. |
Cosmetic Information:
Suppliers:
Bedoukian Research |
e,z-2,6-DODECADIEN-1-AL
≥90.0% (trans,cis), Kosher Odor: A fatty, green, aldehydic character with spice, melon undertones Use: Powerful. Blends well with citrus and florals to add freshness and watery notes. Flavor: green Has application in watermelon, parsley and mushroom flavors. |
BOC Sciences |
For experimental / research use only. |
(E,Z)-2,6-DODECADIENAL 95.0% (sum of isomers)
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M&U International |
E,Z-2,6-Dodecadien-1-al
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Parchem |
(E,Z)-2,6-dodecadien-1-al
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Penta International |
TRANS-2-CIS-6-DODECADIENAL
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for (E,Z)-2,6-dodecadienal usage levels up to: | | 0.5000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.009 (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1800 (μg/person/day) |
Threshold of Concern: | 1800 (μg/person/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 12 |
Click here to view publication 12 |
| average usual ppm | average maximum ppm |
baked goods: | - | - |
beverages(nonalcoholic): | - | 2.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | 0.02000 |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | 2.00000 |
granulated sugar: | - | - |
gravies: | - | 5.00000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 0.02000 |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | 0.01000 |
snack foods: | - | 0.01000 |
soft candy: | - | 2.00000 |
soups: | - | 0.01000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
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Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 5.70000 | 12.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 1.50000 | 14.25000 |
Edible ices, including sherbet and sorbet (03.0): | 0.90000 | 2.98000 |
Processed fruit (04.1): | - | - |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | 5.00000 | 5.03000 |
Confectionery (05.0): | - | - |
Chewing gum (05.3): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 4.80000 | 11.55000 |
Bakery wares (07.0): | 8.00000 | 19.07000 |
Meat and meat products, including poultry and game (08.0): | - | - |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.90000 | 2.98000 |
Eggs and egg products (10.0): | 0.90000 | 2.98000 |
Sweeteners, including honey (11.0): | 0.90000 | 2.98000 |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 2.00000 | 5.00000 |
Foodstuffs intended for particular nutritional uses (13.0): | - | - |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 2.00000 | 4.43000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 1.00000 | 2.00000 |
Ready-to-eat savouries (15.0): | 2.50000 | 4.50000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.90000 | 2.98000 |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 a,ß-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19 View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 70, Revision 1 (FGE.70Rev1): consideration of aliphatic, linear, a,ß-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st-68th-69th meeting) View page or View pdf
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EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):21662-13-5 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :6430759 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:2 |
(2E,6Z)-dodeca-2,6-dienal |
Chemidplus:0021662135 |
References:
Other Information:
Potential Blenders and core components note
For Odor |
aldehydic |
6,7,8- decen-1-ol FR |
(Z)-4- dodecenal FL/FR |
fresh carbaldehyde FR |
iso freshal FR |
mandarine undecenal FL/FR |
3- methyl-4-hexyl oxybutyraldehyde FR |
octanal (aldehyde C-8) FL/FR |
octane nitrile FR |
undecanal FL/FR |
(Z)-8- undecenal FR |
10- undecenal (aldehyde C-11 undecylenic) FL/FR |
amber |
amber carane FR |
angelica root oil FL/FR |
anise |
sweet fennel seed oil FL/FR |
anisic |
ocimum basilicum herb oil FL/FR |
ocimum basilicum leaf oil america FL/FR |
ocimum basilicum leaf oil CO2 extract FL/FR |
balsamic |
guaiyl acetate FL/FR |
citrus |
aldehydic nitrile FR |
citral FL/FR |
citrus specialty FR |
citrus unshiu peel oil FL/FR |
(E)-4- decenal FL/FR |
(Z)-7- decenal FR |
4- decenal FL/FR |
2,4- dimethyl-3-cyclohexene-1-methanyl acetate FR |
lime pyran FR |
limonene aldehyde FR |
marine decadienal FR |
octanal glycol acetal FR |
alpha- sinensal FL/FR |
2- tetradecenal FL/FR |
tetrahydrocitral FL/FR |
fatty |
decanol FL/FR |
3- decen-2-one FL/FR |
methyl 2-hexenoate FL/FR |
6- methyl-5-hepten-2-one propylene glycol acetal FL/FR |
2- nonenal FL/FR |
(E)-2- nonenal FL/FR |
2- octenal FL/FR |
floral |
alpha- amyl cinnamaldehyde diethyl acetal FR |
iso amyl salicylate FL/FR |
citronellyl acetate FL/FR |
cyclamen propanal FR |
beta- damascenone FL/FR |
dihydrojasmone FL/FR |
linalool FL/FR |
mimosa absolute morocco FL/FR |
nonanol FL/FR |
ocean propanal FL/FR |
octahydro-4,7-methano-1H-indene-5-acetaldehyde + 6-methyl-octahydro-4,7-methano-indene-5-carbaldehyd FR |
petitgrain mandarin oil terpeneless FL/FR |
clementine petitgrain oil FL/FR |
fruity |
iso amyl octanoate FL/FR |
ethyl methyl anthranilate FL/FR |
methyl 2-methyl butyrate FL/FR |
methyl 3-nonenoate FL/FR |
octen-1-yl cyclopentanone FL/FR |
(E)-2- undecenal FL/FR |
green |
cilantro leaf oil FL/FR |
cumin acetaldehyde FL/FR |
iso cyclocitral (IFF) FL/FR |
green carbaldehyde FR |
heptanal (aldehyde C-7) FL/FR |
(Z)-4- heptenal FL/FR |
2- heptyl furan FL/FR |
hexanal (aldehyde C-6) FL/FR |
(Z)-3- hexen-1-yl oxyacetaldehyde FR |
(E)-2- hexenal FL/FR |
(Z)-3- hexenal FL/FR |
alpha- hexyl cinnamaldehyde dimethyl acetal FR |
2,4- ivy carbaldehyde FL/FR |
3,5- ivy carbaldehyde FL/FR |
ivy carbaldehyde FL/FR |
2,4- ivy carbaldehyde / methyl anthranilate schiff's base FR |
nerol oxide FL/FR |
(E,Z)-3,6- nonadien-1-ol FL/FR |
(Z)-2- nonen-1-ol FL/FR |
(E)-2- nonen-1-ol FL/FR |
2- nonene nitrile FR |
(E)-2- octen-1-yl acetate FL/FR |
olive oil absolute FL/FR |
herbal |
anthemis nobilis flower extract FL/FR |
anthemis nobilis flower oil roman FL/FR |
sweet basil absolute FL/FR |
1,4- cineole FL/FR |
clary sage oil france FL/FR |
2- dodecenal FL/FR |
geranium cyclohexane FR |
hyssop oil FL/FR |
linalyl octanoate FL/FR |
3- octyl acetate FL/FR |
curled parsley seed oil FL/FR |
rosmarinus officinalis extract FL/FR |
rosmarinus officinalis tincture FL/FR |
salvia sclarea oil FL/FR |
minty |
(-)- menthone FL/FR |
mossy |
oakmoss absolute FL/FR |
muguet |
4-iso butyl 1-(3-methoxy-2-propen-1-yl) benzene FR |
4- ethyl 1-(3-methoxy-2-propen-1-yl) benzene FR |
4- methyl 1-(3-methoxy-2-propen-1-yl) benzene FR |
4- propyl 1-(3-methoxy-2-propen-1-yl) benzene FR |
soapy |
methyl anthranilate / hexyl cinnamaldehyde schiff's base FR |
spicy |
cumin seed absolute FL/FR |
cuminaldehyde FL/FR |
waxy |
decanal diethyl acetal FL/FR |
9- decenoic acid FL/FR |
1- dodecanol FL/FR |
heptyl octanoate FL/FR |
2,4- nonadien-1-ol FL/FR |
octanol FL/FR |
octyl isobutyrate FL/FR |
propyl decanoate FL/FR |
For Flavor |
No flavor group found for these |
citrus unshiu peel oil FL/FR |
9- decen-2-one FL |
4- decenal FL/FR |
(Z)-4- dodecenal FL/FR |
epoxy-2-decenal FL |
ethyl methyl anthranilate FL/FR |
furfuryl hexanoate FL |
guaiyl acetate FL/FR |
(E,E)-2,4- heptadien-1-ol FL |
hexanal butane-2,3-diol acetal FL |
hexyl (E)-2-hexenoate FL |
ivy carbaldehyde FL/FR |
3,5- ivy carbaldehyde FL/FR |
methyl 2-hexenoate FL/FR |
6- methyl octanal FL |
6- methyl-5-hepten-2-one propylene glycol acetal FL/FR |
2- octenal FL/FR |
propyl decanoate FL/FR |
2- propyl pyridine FL |
2- tetradecenal FL/FR |
tetrahydrocitral FL/FR |
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(±)-3-( methyl thio) heptanal FL |
absinthe |
absinthe |
absinthe flavor FL |
aldehydic |
octanal (aldehyde C-8) FL/FR |
anise |
sweet fennel seed oil FL/FR |
citrus |
cilantro leaf oil FL/FR |
citral FL/FR |
linalool FL/FR |
clementine petitgrain oil FL/FR |
alpha- sinensal FL/FR |
cooling |
1,4- cineole FL/FR |
creamy |
octyl isobutyrate FL/FR |
fatty |
2,4- decadienal FL |
2- dodecenal FL/FR |
(E,E)-2,4- heptadienal FL |
2- heptyl furan FL/FR |
2,4- nonadien-1-ol FL/FR |
2,4- nonadienal FL |
(Z)-2- nonen-1-ol FL/FR |
2- nonenal FL/FR |
10- undecenal (aldehyde C-11 undecylenic) FL/FR |
floral |
citronellyl acetate FL/FR |
dihydrojasmone FL/FR |
mimosa absolute morocco FL/FR |
ocean propanal FL/FR |
fruity |
iso amyl octanoate FL/FR |
linalyl octanoate FL/FR |
methyl (E)-3-nonenoate FL |
methyl 2-methyl butyrate FL/FR |
methyl 3-nonenoate FL/FR |
octen-1-yl cyclopentanone FL/FR |
petitgrain mandarin oil terpeneless FL/FR |
green |
iso amyl salicylate FL/FR |
angelica root oil FL/FR |
cumin acetaldehyde FL/FR |
iso cyclocitral (IFF) FL/FR |
3- decen-2-one FL/FR |
(E)-4- decenal FL/FR |
dihydroxyacetophenone (mixed isomers) FL |
heptanal (aldehyde C-7) FL/FR |
(E)-2- heptenal FL |
(Z)-4- heptenal FL/FR |
(E,E)-2,4- hexadienal FL |
2,4- hexadienal FL |
hexanal (aldehyde C-6) FL/FR |
(Z)-3- hexenal FL/FR |
(E)-2- hexenal FL/FR |
2- hexyl pyridine FL |
2,4- ivy carbaldehyde FL/FR |
nerol oxide FL/FR |
(E,Z)-3,6- nonadien-1-ol FL/FR |
(E)-2- nonen-1-ol FL/FR |
(E)-2- nonenal FL/FR |
oakmoss absolute FL/FR |
(E,E)-2,4- octadienal FL |
2,4- octadienal FL |
(E)-2- octen-1-yl acetate FL/FR |
3- octyl acetate FL/FR |
sorbyl acetate FL |
herbal |
anthemis nobilis flower extract FL/FR |
anthemis nobilis flower oil roman FL/FR |
sweet basil absolute FL/FR |
clary sage oil france FL/FR |
hyssop oil FL/FR |
ocimum basilicum herb oil FL/FR |
ocimum basilicum leaf oil america FL/FR |
ocimum basilicum leaf oil CO2 extract FL/FR |
curled parsley seed oil FL/FR |
rosmarinus officinalis extract FL/FR |
rosmarinus officinalis tincture FL/FR |
salvia sclarea oil FL/FR |
meaty |
12- methyl tridecanal FL |
minty |
(-)- menthone FL/FR |
oily |
olive oil absolute FL/FR |
pungent |
acetaldehyde FL |
soapy |
1- dodecanol FL/FR |
spicy |
cumin seed absolute FL/FR |
cuminaldehyde FL/FR |
waxy |
decanal diethyl acetal FL/FR |
decanol FL/FR |
9- decenoic acid FL/FR |
heptyl octanoate FL/FR |
mandarine undecenal FL/FR |
nonanol FL/FR |
octanol FL/FR |
undecanal FL/FR |
(E)-2- undecenal FL/FR |
woody |
beta- damascenone FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(2E,6Z)- | dodeca-2,6-dienal | (2trans,6cis)- | dodeca-2,6-dienal | (E,Z)-2,6- | dodecadien-1-al | (E)-2,(Z)-6- | dodecadien-1-al | 2-trans-6-cis- | dodecadien-1-al | 2,6- | dodecadien-1-al | E,Z-2,6- | dodecadien-1-al | trans-2,cis-6- | dodecadien-1-al | trans,cis-2,6- | dodecadien-1-al | 2-trans-6-cis- | dodecadienal | trans-2-cis-6- | dodecadienal | trans,cis-2,6- | dodecadienal | 2,6- | dodecadienal, (2E,6Z)- |
Articles:
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