EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ethyl methyl anthranilate
ethyl N-methylanthranilate

Supplier Sponsors

Name:ethyl 2-methylaminobenzoate
CAS Number: 35472-56-1Picture of molecule3D/inchi
FDA UNII: HQ8T25BTTC
Nikkaji Web:J169.109K
MDL:MFCD11174593
CoE Number:632
XlogP3:3.30 (est)
Molecular Weight:179.21901000
Formula:C10 H13 N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1546 ethyl N-methylanthranilate
DG SANTE Food Flavourings:09.765 ethyl N-methylanthranilate
FEMA Number:4116 ethyl N-methylanthranilate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):35472-56-1 ; ETHYL N-METHYLANTHRANILATE
 
Physical Properties:
Appearance:pale yellow solid (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.12000 @ 25.00 °C.
Refractive Index:1.57200 @ 25.00 °C.
Melting Point: 36.00 °C. @ 760.00 mm Hg
Boiling Point: 278.00 °C. @ 760.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.009000 mmHg @ 25.00 °C. (est)
Flash Point: 242.00 °F. TCC ( 116.67 °C. )
logP (o/w): 3.224 (est)
Soluble in:
 alcohol
 water, very slightly
 water, 83.89 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Type: fruity
sweet mandarin petitgrain
Odor Description:at 100.00 %. soft sweet mandarin petitgrain
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Matrix Scientific
For experimental / research use only.
Ethyl 2-(methylamino)benzoate, 95+%
Parchem
ethyl methyl anthranilate
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for ethyl methyl anthranilate usage levels up to:
  4.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.028 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.04 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 2300 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 22
Click here to view publication 22
 average usual ppmaverage maximum ppm
baked goods: 10.0000050.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: 5.0000025.00000
cheese: 7.0000035.00000
chewing gum: --
condiments / relishes: 2.0000025.00000
confectionery froastings: 10.0000050.00000
egg products: --
fats / oils: 5.0000025.00000
fish products: 2.0000010.00000
frozen dairy: 7.0000035.00000
fruit ices: 10.0000050.00000
gelatins / puddings: --
granulated sugar: --
gravies: 5.0000025.00000
hard candy: --
imitation dairy: 7.0000035.00000
instant coffee / tea: --
jams / jellies: --
meat products: 5.0000025.00000
milk products: 7.0000035.00000
nut products: --
other grains: 5.0000025.00000
poultry: 2.0000010.00000
processed fruits: 7.0000035.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 5.0000025.00000
snack foods: 20.00000100.00000
soft candy: --
soups: 5.0000025.00000
sugar substitutes: --
sweet sauces: 5.0000025.00000
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 7.0000035.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 5.0000025.00000
Edible ices, including sherbet and sorbet (03.0): 10.0000050.00000
Processed fruit (04.1): 7.0000035.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 10.0000050.00000
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.0000025.00000
Bakery wares (07.0): 10.0000050.00000
Meat and meat products, including poultry and game (08.0): 2.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.0000010.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.0000025.00000
Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): --
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
Ready-to-eat savouries (15.0): 20.00000100.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 84, (FGE.84)[1] - Consideration of Anthranilate derivatives evaluated by JECFA (65th meeting) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :101365
National Institute of Allergy and Infectious Diseases:Data
ethyl 2-methylaminobenzoate
Chemidplus:0035472561
 
References:
 ethyl 2-methylaminobenzoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:35472-56-1
Pubchem (cid):101365
Pubchem (sid):135058656
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):HMDB33763
FooDB:FDB011905
Export Tariff Code:2922.49.3800
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
aldehydic
mandarine undecenal
FL/FR
tridecanal
FL/FR
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
balsamic
(E)-
cinnamyl butyrate
FL/FR
citrus
benzyl anthranilate
FR
citrus unshiu peel oil
FL/FR
curacao peel oil
FL/FR
dimethyl octenone
FR
2,4-
dimethyl-3-cyclohexene-1-methanyl acetate
FR
grapefruit indene
FR
grapefruit mercaptan
FL/FR
grapefruit nitrile
FR
grapefruit oil c.p. california
FL/FR
grapefruit oil CO2 extract (citrus paradisi macf. var. falvedo)
FL/FR
grapefruit oil terpeneless
FL/FR
grapefruit pentanol
FR
lime oil distilled terpeneless
FL/FR
mandarin oil italy
FL/FR
myrmac aldehyde
FR
(+)-
nootkatone
FL/FR
rhubafuran
FR
alpha-
sinensal
FL/FR
alpha-
terpinyl methyl ether
FL/FR
(±)-2,4,8-
trimethyl-7-nonen-2-ol
FL/FR
valencene
FL/FR
waxy nitrile
FR
coconut
(R)-gamma-
nonalactone
FL/FR
fatty
(S)-gamma-
decalactone
FL/FR
(E,Z)-2,6-
dodecadienal
FL/FR
floral
allyl anthranilate
FL/FR
cassis oxime 10%
FR
decyl anthranilate
FR
ethyl anthranilate
FL/FR
gardenia amide
FR
gardenia decalone
FR
gardenia pentyl acetate
FR
magnolia indene
FR
methyl jasmonate
FL/FR
neroli oil
FL/FR
neroli oil bigarde
FL/FR
neroli oil replacer
FR
neryl acetate
FL/FR
octanal / methyl anthranilate schiff's base
FR
bitter
orangeflower water absolute
FL/FR
peony acetonitrile
FR
petitgrain mandarin oil
FL/FR
petitgrain mandarin oil terpeneless
FL/FR
phenethyl anthranilate
FL/FR
(Z,E)-
phytol
FL/FR
iso
phytol
FL/FR
fruity
apple crotonate
FR
iso
butyl anthranilate
FL/FR
butyl anthranilate
FL/FR
iso
butyl isobutyrate
FL/FR
iso
butyl methyl anthranilate
FL/FR
ethyl 3-hydroxyhexanoate
FL/FR
ethyl propionate
FL/FR
fig crotonate
FR
grape butyrate
FL/FR
grapefruit acetal
FR
3-
hexanone
FL/FR
(Z)-3-
hexen-1-yl anthranilate
FL/FR
methyl anthranilate
FL/FR
methyl formyl anthranilate
FL/FR
nerolidyl isobutyrate
FR
iso
propenyl acetate
FL/FR
propyl heptanoate
FL/FR
green
acetaldehyde benzyl 2-methoxyethyl acetal
FL/FR
green carboxylate
FR
(E)-2-
hexen-1-yl isovalerate
FL/FR
hexyl isobutyrate
FL/FR
herbal
6-
acetoxydihydrotheaspirane
FL/FR
white
cognac oil
FL/FR
(E)-2-
dodecenal
FL/FR
3-
octyl acetate
FL/FR
naphthyl
beta-
naphthyl ethyl ether
FL/FR
spicy
cinnamyl propionate
FL/FR
sulfurous
grapefruit menthane
FL/FR
waxy
ethyl decanoate
FL/FR
phytyl acetate
FL/FR
For Flavor
No flavor group found for these
acetaldehyde benzyl 2-methoxyethyl acetal
FL/FR
6-
acetoxydihydrotheaspirane
FL/FR
allyl anthranilate
FL/FR
iso
butyl methyl anthranilate
FL/FR
(E)-
cinnamyl butyrate
FL/FR
citrus unshiu peel oil
FL/FR
curacao peel oil
FL/FR
(S)-gamma-
decalactone
FL/FR
dihydronootkatone
FL
4-
mercapto-4-methyl-2-pentanol
FL
methyl formyl anthranilate
FL/FR
(R)-gamma-
nonalactone
FL/FR
3-oxo
octanoic acid glyceride
FL
balsamic
balsamic
(Z,E)-
phytol
FL/FR
citrus
grapefruit mercaptan
FL/FR
grapefruit oil c.p. california
FL/FR
grapefruit oil CO2 extract (citrus paradisi macf. var. falvedo)
FL/FR
grapefruit oil terpeneless
FL/FR
lime oil distilled terpeneless
FL/FR
mandarin oil italy
FL/FR
(+)-
nootkatone
FL/FR
petitgrain mandarin oil
FL/FR
alpha-
sinensal
FL/FR
(±)-2,4,8-
trimethyl-7-nonen-2-ol
FL/FR
valencene
FL/FR
ethereal
iso
propenyl acetate
FL/FR
fatty
(E,E)-2,4-
dodecadienal
FL
10-
undecenal (aldehyde C-11 undecylenic)
FL/FR
floral
cinnamyl propionate
FL/FR
(Z)-3-
hexen-1-yl anthranilate
FL/FR
methyl jasmonate
FL/FR
neroli oil
FL/FR
neroli oil bigarde
FL/FR
neryl acetate
FL/FR
bitter
orangeflower water absolute
FL/FR
phenethyl anthranilate
FL/FR
fruity
butyl anthranilate
FL/FR
iso
butyl anthranilate
FL/FR
iso
butyl isobutyrate
FL/FR
ethyl 3-hydroxyhexanoate
FL/FR
ethyl anthranilate
FL/FR
ethyl propionate
FL/FR
furfuryl butyrate
FL
3-
hexanone
FL/FR
methyl anthranilate
FL/FR
petitgrain mandarin oil terpeneless
FL/FR
fusel
white
cognac oil
FL/FR
green
(E,Z)-2,6-
dodecadienal
FL/FR
grape butyrate
FL/FR
(E)-2-
hexen-1-yl isovalerate
FL/FR
hexyl isobutyrate
FL/FR
3-
octyl acetate
FL/FR
nutty
phytyl acetate
FL/FR
oily
iso
phytol
FL/FR
powdery
beta-
naphthyl ethyl ether
FL/FR
sulfurous
grapefruit menthane
FL/FR
waxy
(E)-2-
dodecenal
FL/FR
ethyl decanoate
FL/FR
mandarine undecenal
FL/FR
propyl heptanoate
FL/FR
tridecanal
FL/FR
woody
alpha-
terpinyl methyl ether
FL/FR
 
Potential Uses:
FRfruit
FLfruit tropical fruit
FRjasmin
FRmandarin
FRneroli
FRorange blossom
FRpetitgrain
 topnotes
 
Occurrence (nature, food, other):note
 star fruit fruit
Search Trop Picture
 star fruit fruit
Search Trop Picture
 
Synonyms:
 benzoic acid, 2-(methylamino)-, ethyl ester
 ethyl 2-(methyl amino) benzoate
 ethyl 2-(methylamino)benzoate
 ethyl 2-methylaminobenzoate
 ethyl N-methylanthranilate
2-(methyl amino) benzoic acid ethyl ester
 
 
Notes:
Used as a food additive [EAFUS]
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