EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

laevo-borneol
L-borneol

Supplier Sponsors

Fragrance Demo Formulas
Name:(1S,4R,6R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-ol
CAS Number: 464-45-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-353-1
FDA UNII: 1Y84986J9Q
Beilstein Number:2038053
MDL:MFCD00003759
XlogP3:2.70 (est)
Molecular Weight:154.25266000
Formula:C10 H18 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FEMA Number:2157 L-borneol
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Appearance:colorless crystals (est)
Assay: 80.00 to 100.00
Food Chemicals Codex Listed: No
Optical Rotation:-20.00 to 0.00
Melting Point: 206.00 to 208.00 °C. @ 760.00 mm Hg
Boiling Point: 210.00 to 212.00 °C. @ 779.00 mm Hg
Boiling Point: 203.00 to 204.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.040000 mmHg @ 25.00 °C. (est)
Vapor Density:5.3 ( Air = 1 )
Flash Point: 150.00 °F. TCC ( 65.56 °C. )
logP (o/w): 3.010
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 dipropylene glycol
 propylene glycol
 water, 1186 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 bath foam
 cream
 detergent
 lotion
 non-discoloring in most media
 shampoo
 
Organoleptic Properties:
Odor Type: balsamic
Odor Strength:medium ,
recommend smelling in a 10.00 % solution or less
Substantivity:16 hour(s) at 100.00 %
pine woody camphoreous peppery
Odor Description:at 10.00 % in dipropylene glycol. pine woody camphor
Luebke, William tgsc, (1989)
Odor sample from: CA Aromatics Company Inc.
Flavor Type: camphoreous
earthy minty camphoreous herbal woody musty
Taste Description: earthy minty camphoreous herbal woody musty
Luebke, William tgsc, (1989)
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
L(-)-Borneol 97%
BOC Sciences
For experimental / research use only.
laevo-Borneol
Citrus and Allied Essences
laevo-Borneol Crystals 96%
Market Report
Citrus and Allied Essences
laevo-Borneol Crystals Extra (80-20)
Endeavour Specialty Chemicals
Natural borneol
Speciality Chemical Product Groups
Ernesto Ventós
BORNEOL 100% NATURAL
ExtraSynthese
For experimental / research use only.
(-)-Borneol (GC) ≥98% (sum of enantiomers)
Fleurchem
l-borneol natural
Fleurchem
l-borneol
Foreverest Resources
L-Borneol 95%
Odor: woody
Use: L-Borneol also call as Mei Slice, is the crystallization of fresh branch and leaf of Typus physiologies Cinnanloni through distillation of water vapor.
Indukern F&F
BORNEOL PURE
Odor: FRESH, CAMPHORATED, MENTHOLATED
M&U International
laevo-Borneol
Moellhausen
BORNEOL LAEVO 97/3
OQEMA
Borneol Crystals
Penta International
L-BORNEOL CRYSTALS 60/40 (2-PEAK)
Penta International
L-BORNEOL CRYSTALS 80%
Penta International
L-BORNEOL CRYSTALS PURE 96%
Penta International
L-BORNEOL NATURAL
Prodasynth
BORNEOL 65%
(60-65%; ISOBORNEOL 30-40%)
Odor: CHARACTERISTIC, DRY, CAMPHORACEOUS
R C Treatt & Co Ltd
Borneol US Natural
Halal, Kosher
Reincke & Fichtner
laevo-Borneol
Robinson Brothers
Natural borneol
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
(-)-Borneol
Sigma-Aldrich
For experimental / research use only.
(-)-Borneol analytical standard
SRS Aromatics
BORNEOL CRYSTALS
Odor: Pine, Woody, Camphor
TCI AMERICA
For experimental / research use only.
(-)-Borneol >95.0%(GC)
Vigon International
BORNEOL LAEVO NATURAL
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 36/39 - Wear suitable clothing and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
20 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 5800 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 655, 1978.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for laevo-borneol usage levels up to:
  8.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -5.10000
beverages(nonalcoholic): 0.250001.40000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -0.30000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.40000
fruit ices: -1.40000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -3.70000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):464-45-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10049
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1312
WGK Germany:2
(1S,4R,6R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-ol
Chemidplus:0000464459
RTECS:DT5095000 for cas# 464-45-9
 
References:
Leffingwell:Chirality or Article
 (1S,4R,6R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:464-45-9
Pubchem (cid):10049
Pubchem (sid):134973830
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
KEGG (GenomeNet):C01766
HMDB (The Human Metabolome Database):HMDB34976
FooDB:FDB014588
Export Tariff Code:2906.19.0000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Formulations/Preparations:
grades: technical.
 
Potential Blenders and core components note
For Odor
alcoholic
iso
propyl alcohol
FL/FR
aldehydic
agrumen nitrile
FR
dodecanal (aldehyde C-12 lauric)
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
amber
amber naphthofuran
FL/FR
ambrette seed oil
FL/FR
angelica root oil
FL/FR
cistus ladaniferus resinoid
FL/FR
animal
costus valerolactone
FR
balsamic
amyris wood oil
FL/FR
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
dextro,laevo-iso
borneol
FL/FR
dextro-
borneol
FL/FR
dextro,laevo-
borneol
FL/FR
iso
bornyl acetate
FL/FR
bornyl acetate
FL/FR
iso
bornyl formate
FL/FR
iso
bornyl isobutyrate
FL/FR
iso
bornyl methyl ether
FL/FR
iso
bornyl propionate
FL/FR
brachyleana hutchinsii wood oil
FR
fir balsam absolute
FR
myrrh oil
FL/FR
opoponax resinoid replacer
FR
valerian rhizome absolute
FL/FR
camphoreous
2,6-
dimethyl-3-oxatricyclo(4.2.1.0*2,4*)nonane
FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
citrus
myrcenyl acetate
FL/FR
earthy
2-
ethyl fenchol
FL/FR
(-)-alpha-
fenchol
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
floral
acetophenone
FL/FR
alpha-
amyl cinnamaldehyde
FL/FR
bois de rose oil peru
FL/FR
cassie absolute
FL/FR
coriander seed oil
FL/FR
dihydrocarvyl acetate
FL/FR
dimethyl benzyl carbinol
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
ho leaf oil
FR
beta-
ionone
FL/FR
2-
methyl naphthalene
FL/FR
mimosa absolute morocco
FL/FR
bitter
orangeflower concrete morocco
FR
petitgrain bigarade oil
FL/FR
fruity
3-
allyl oxy-1,4-dimethyl bicyclo(3.2.1)octane
FR
(R)-gamma-
dodecalactone
FL/FR
menthyl isovalerate
FL/FR
green
geranic acid
FL/FR
iso
green methanoindene
FR
rose leaf absolute (rosa centifolia)
FL/FR
3,5,5-
trimethyl hexanol
FL/FR
herbal
1-
allyl-2,2,7,7-tetramethyl cycloheptanol
FR
anethum graveolens herb oil
FL/FR
angelica archangelica seed extract
FL/FR
anthemis nobilis flower oil roman
FL/FR
barosma betulina leaf oil
FL/FR
camphene carbinyl acetate
FR
chamomile oil morocco
FR
1,8-
cineole
FL/FR
daucus carota fruit oil
FL/FR
iso
dihydrolavandulal
FL/FR
dimethyl cyclormol (IFF)
FR
delta-
elemene
FL/FR
geranic oxide
FL/FR
herbal dioxane
FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
hyssopus officinalis extract
FL/FR
hyssopus officinalis leaf tincture
FL/FR
spike
lavender oil
FL/FR
melaleuca leucadendron cajaputi oil
FL/FR
methyl cyclogeranate (Firmenich)
FR
myrtenol
FL/FR
origanum oil
FL/FR
origanum oil greece
FL/FR
curled
parsley leaf oil
FL/FR
pine hexanol
FR
alpha-
pinene
FL/FR
beta-
pinene
FL/FR
rosemary absolute
FL/FR
rosemary oil
FL/FR
rosemary oil africa
FL/FR
rosemary oil morocco
FL/FR
rosemary oil replacer
FR
rosemary oil spain
FL/FR
rosemary oil tunisia
FL/FR
sabinene hydrate
FL/FR
tea leaf absolute
FL/FR
theaspirane
FL/FR
thymol
FL/FR
yerba mate absolute
FL/FR
honey
methyl phenyl acetate
FL/FR
mentholic
laevo-
menthol
FL/FR
(±)-
menthol
FL/FR
peppermint cyclohexanone
FL/FR
iso
pulegyl acetate
FL/FR
minty
agathosma crenulata leaf oil
FL/FR
peppermint oil idaho
FL/FR
mossy
oakmoss absolute
FL/FR
oakmoss distillates
FL/FR
veramoss (IFF)
FR
musk
acetyl ethyl tetramethyl tetralin replacer
FR
musk decanolide
FR
musty
ketoiso
phorone
FL/FR
nutty
2-
ethyl pyrazine
FL/FR
powdery
para-
anisyl alcohol
FL/FR
spicy
cassia bark oil china
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
2,5-
dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate
FR
elettaria cardamomum seed oil
FL/FR
ginger fragrance
FR
ginger root absolute
FL/FR
ginger root oil china
FL/FR
ginger root oil replacer
FR
ginger specialty
FR
grains of paradise oil
FL/FR
methyl heptadienone
FL/FR
origanum majorana oleoresin
FL/FR
black
pepper oil CO2 extract
FL/FR
pimenta acris leaf oil
FL/FR
white
sassafras oil
FL/FR
terpenic
frankincense oil
FL/FR
juniperus communis fruit oil
FL/FR
pine needle oil dwarf
FL/FR
thujonic
armoise oil
FR
cedarleaf oil terpeneless
FR
tonka
tonka bean absolute
FR
tropical
genet absolute
FL/FR
vanilla
vanillin
FL/FR
waxy
ethyl laurate
FL/FR
woody
agarwood oil (aetoxylon sympetalum)
FR
2-tert-
butyl cyclohexanone
FR
cabreuva wood oil
FR
atlas
cedarwood oil
FR
cistus twig/leaf oil
FL/FR
guaiacwood oil 20% in gurjun balsam oil
FR
gurjun balsam oil
FR
hinoki root oil
FR
homalomena rubescens root oil
FR
juniper berry oil terpenes
FR
methyl cedryl ketone
FL/FR
patchouli ethanone
FR
patchouli oil
FL/FR
sandalwood oil CO2 extract
FL/FR
santall
FR
spikenard oil CO2 extract
FL/FR
thuja occidentalis leaf oil
FL/FR
woody acetate
FR
For Flavor
No flavor group found for these
dextro-
borneol
FL/FR
dextro,laevo-
borneol
FL/FR
iso
bornyl methyl ether
FL/FR
cistus ladaniferus resinoid
FL/FR
(R)-gamma-
dodecalactone
FL/FR
delta-
elemene
FL/FR
grains of paradise oil
FL/FR
(Z)-
linalool oxide (furanoid)
FL/FR
white
sassafras oil
FL/FR
spikenard oil CO2 extract
FL/FR
alcoholic
alcoholic
iso
propyl alcohol
FL/FR
amber
amber naphthofuran
FL/FR
ambrette seed oil
FL/FR
balsamic
siam
benzoin resinoid
FL/FR
benzyl salicylate
FL/FR
iso
bornyl isobutyrate
FL/FR
iso
bornyl propionate
FL/FR
myrrh oil
FL/FR
camphoreous
dextro,laevo-iso
borneol
FL/FR
bornyl acetate
FL/FR
(-)-alpha-
fenchol
FL/FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
geranic oxide
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
rosemary oil tunisia
FL/FR
citrus
myrcenyl acetate
FL/FR
petitgrain bigarade oil
FL/FR
ketoiso
phorone
FL/FR
cooling
spike
lavender oil
FL/FR
iso
menthol
FL
laevo-
menthol
FL/FR
sabinene hydrate
FL/FR
theaspirane
FL/FR
WS-3
FL
earthy
2-
ethyl fenchol
FL/FR
floral
bois de rose oil peru
FL/FR
dihydrocarvyl acetate
FL/FR
methyl phenyl acetate
FL/FR
mimosa absolute morocco
FL/FR
fruity
para-
anisyl alcohol
FL/FR
menthyl isovalerate
FL/FR
valerian rhizome absolute
FL/FR
green
angelica root oil
FL/FR
geranic acid
FL/FR
methyl heptadienone
FL/FR
oakmoss absolute
FL/FR
iso
phorone
FL
rose leaf absolute (rosa centifolia)
FL/FR
3,5,5-
trimethyl hexanol
FL/FR
hay
genet absolute
FL/FR
herbal
anethum graveolens herb oil
FL/FR
angelica archangelica seed extract
FL/FR
anthemis nobilis flower oil roman
FL/FR
barosma betulina leaf oil
FL/FR
cardamom distillates
FL
cardamom flavor
FL
coriander seed oil
FL/FR
daucus carota fruit oil
FL/FR
iso
dihydrolavandulal
FL/FR
dill flavor
FL
eucalyptus flavor
FL
hyssopus officinalis extract
FL/FR
hyssopus officinalis leaf tincture
FL/FR
melaleuca leucadendron cajaputi oil
FL/FR
origanum oil
FL/FR
origanum oil greece
FL/FR
parsley flavor
FL
curled
parsley leaf oil
FL/FR
curled
parsley oleoresin
FL
rosemary absolute
FL/FR
rosemary oil
FL/FR
rosemary oil africa
FL/FR
rosemary oil morocco
FL/FR
rosemary oil spain
FL/FR
yerba mate absolute
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
mentholic
(±)-
menthol
FL/FR
peppermint cyclohexanone
FL/FR
minty
agathosma crenulata leaf oil
FL/FR
1,8-
cineole
FL/FR
myrtenol
FL/FR
peppermint oil idaho
FL/FR
mossy
oakmoss distillates
FL/FR
nutty
2-
ethyl pyrazine
FL/FR
oily
2-
methyl naphthalene
FL/FR
phenolic
thymol
FL/FR
pine
pine needle oil dwarf
FL/FR
beta-
pinene
FL/FR
powdery
acetophenone
FL/FR
smoky
dextro-
xylose
FL
soapy
dodecanal (aldehyde C-12 lauric)
FL/FR
spicy
cassia bark oil china
FL/FR
cassie absolute
FL/FR
clove bud oil
FL/FR
black
currant bud absolute
FL/FR
elettaria cardamomum seed oil
FL/FR
ginger root absolute
FL/FR
ginger root oil china
FL/FR
origanum majorana oleoresin
FL/FR
black
pepper oil CO2 extract
FL/FR
pimenta acris leaf oil
FL/FR
tea
mate flavor
FL
tea leaf absolute
FL/FR
yerba mate flavor
FL
terpenic
juniperus communis fruit oil
FL/FR
para-
menthatriene
FL
tropical
alpha-
amyl cinnamaldehyde
FL/FR
vanilla
vanillin
FL/FR
waxy
ethyl laurate
FL/FR
alpha-
hexyl cinnamaldehyde
FL/FR
2-
methyl undecanal (aldehyde C-12 mna)
FL/FR
woody
amyris wood oil
FL/FR
iso
bornyl acetate
FL/FR
iso
bornyl formate
FL/FR
cistus twig/leaf oil
FL/FR
frankincense oil
FL/FR
beta-
ionone
FL/FR
methyl cedryl ketone
FL/FR
patchouli oil
FL/FR
alpha-
pinene
FL/FR
iso
pulegyl acetate
FL/FR
sandalwood oil CO2 extract
FL/FR
thuja occidentalis leaf oil
FL/FR
 
Potential Uses:
FRagate
FRbalsam
FRbayberry
FRbouquet
FL/FRcamphor tree bark
FRcardamom oil replacer
FLcarrot
FRcastoreum
FRcedar
FRcedar forest
FRcedarwood
FRchristmas
FRcinnamon
FRcitronella
FL/FRcoriander
FRearth
 fir
FRfir balsam
FRfir needle oil replacer
 fixer
FRfrankincense
FRgeranium
FRginger
FRherbal
FRhollyberry
FRjuniper berry
FRlavandin
FRlavender
FL/FRlavender spike lavender
FRmace
FRmoss
FRmyrrh
FRnutmeg
FRpatchouli
FRpeppermint
FRpine
FRrosemary
FRsage
FL/FRsnake root
FRspice
FRspruce
FRsweet grass
 truffle
FL/FRvalerian
FRwoody
 
Occurrence (nature, food, other):note
 cardamom
Search Trop Picture
 carrot
Search Trop Picture
 cinnamon leaf
Search Trop Picture
 citronella
Search PMC Picture
 coriander oil
Search Trop Picture
 cornmint leaf
Search Trop Picture
 geranium
Search Trop Picture
 ginger
Search Trop Picture
 lime oil distilled
Search Trop Picture
 mace
Search Trop Picture
 nutmeg seed
Search Trop Picture
 oakmoss
Search Trop Picture
 olibanum
Search Trop Picture
 pine needle
Search PMC Picture
 rosemary
Search Trop Picture
 sage
Search Trop Picture
 snake root root
Search Trop Picture
 thyme plant
Search Trop Picture
 valerian root
Search Trop Picture
 
Synonyms:
 bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1S,2R,4R)-
L-2-bornanol
L-endo-2-bornanol
laevo-2-bornanol
laevo-endo-2-bornanol
((1S)-endo)-(-)-borneol
(1S,2R,4S)-(-)-borneol
L-borneol
L-borneol crystals 80%
L-borneol crystals 95%
laevo-borneol crystals extra (80-20)
L-borneol flakes
L-borneol natural
L-borneol pure
L-2-camphanol
L-endo-2-camphanol
laevo-2-camphanol
laevo-endo-2-camphanol
L-camphol
laevo-camphol
L-endo-2-hydroxybornane
laevo-2-hydroxybornane
laevo-endo-2-hydroxycamphane
(1S-endo)-1,7,7-trimethyl bicyclo(2.2.1)heptan-2-ol
L-1,7,7-trimethyl bicyclo(2.2.1)heptan-2-ol
laevo-1,7,7-trimethyl bicyclo(2.2.1)heptan-2-ol
(1S,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
(1S,4R,6R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-ol
 

Articles:

PubMed:Fragrance material review on l-borneol.
PubMed:Esters of pyromellitic acid. Part II. Esters of chiral alcohols: para pyromellitate diesters as a novel class of resolving agents and use of pyromellitates as duplicands for chiral purification.
PubMed:Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs.
PubMed:[Identification and determination of borneol in liyan gao by TLC and GC].
PubMed:Effect of a dietary protein deficiency on the development of hepatic drug-metabolizing enzymes in young rats.
PubMed:The biochemistry and physiology of glucuronic acid: (a) The occurrence of conjugated glucuronic acids in the animal body. (b) Observations on the conjugation of d- and l-borneol.
 
Notes:
Accentuate peppery camphor notes. Constit. of Blumea balsamifera (sambong)
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