|
Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless solid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 25.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 255.00 to 256.00 °C. @ 760.00 mm Hg
|
| Acid Value: | 1.00 max. KOH/g
|
| Vapor Pressure: | 0.016000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 225.00 °F. TCC ( 107.22 °C. )
|
| logP (o/w): | 0.754 (est) |
| Soluble in: |
| | alcohol | | | water | | | water, 113.3 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor Type: herbal |
| herbal minty |
| Odor Description:at 10.00 % in dipropylene glycol. herbal minty |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for piperitenone oxide usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.20 (μg/capita/day) |
| Structure Class: | III |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 22 |
| Click here to view publication 22 |
| | average usual ppm | average maximum ppm |
| baked goods: | 3.00000 | 15.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | 2.00000 | 10.00000 |
| cheese: | 2.00000 | 10.00000 |
| chewing gum: | - | - |
| condiments / relishes: | 5.00000 | 25.00000 |
| confectionery froastings: | - | - |
| egg products: | 2.00000 | 10.00000 |
| fats / oils: | 2.00000 | 10.00000 |
| fish products: | 3.00000 | 15.00000 |
| frozen dairy: | 5.00000 | 25.00000 |
| fruit ices: | 1.00000 | 5.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | 3.00000 | 15.00000 |
| poultry: | - | - |
| processed fruits: | 1.00000 | 5.00000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | 2.00000 | 10.00000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
References:
| | 1-methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 61942 |
| Pubchem (sid): | 135018639 |
| Pherobase: | View |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 7-oxa | bicyclo(4.1.0)heptan-2-one, 6-methyl-3-(1-methylethylidene)- | | 1,2- | epoxy-p-menth-4(8)-en-3-one | | 1,2- | epoxy-para-menth-4(8)-en-3-one | | p- | menth-4(8)-en-3-one, 1,2-epoxy- | | 6- | methyl-3-(1-methyl ethylidene)-7-oxabicyclo(4.1.0)heptan-2-one | | 6- | methyl-3-(1-methylethylidene)-7-oxabicyclo(4.1.0)heptan-2-one | | 1- | methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one | | | rotundifolone |
Articles:
| Info:epoxides |
| PubMed:Chemical composition and antimicrobial activity of the essential oil of Plectranthus mollis (Lamiaceae) from Western Ghats Region, Karnataka, India. |
| PubMed:Discrimination of fennel chemotypes applying IR and Raman spectroscopy: discovery of a new γ-asarone chemotype. |
| PubMed:In vitro inhibition of herpes simplex virus type 1 replication by Mentha suaveolens essential oil and its main component piperitenone oxide. |
| PubMed:Antioxidant Activity and Volatile and Phenolic Profiles of Essential Oil and Different Extracts of Wild Mint (Mentha longifolia) from the Pakistani Flora. |
| PubMed:Essential oils of Micromeria dalmatica Benth., a Balkan endemic species of section Pseudomelissa. |
| PubMed:Biological activities of Eremostachys laevigata Bunge. grown in Iran. |
| PubMed:In vitro production of M. × piperita not containing pulegone and menthofuran. |
| PubMed:Essential-oil diversity of three Calamintha species from Greece. |
| PubMed:Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia). |
| PubMed:Chemical and morphological diversity in wild populations of Mentha longifolia in Israel. |
| PubMed:Composition of the essential oil of Origanum tyttanthum from Tajikistan. |
| PubMed:Mentha longifolia in vitro cultures as safe source of flavouring ingredients. |
| PubMed:HS-SPME-GC×GC-qMS volatile metabolite profiling of Chrysolina herbacea frass and Mentha spp. leaves. |
| PubMed:Comparative study of volatile oil compositions of two Plectranthus species from northern India. |
| PubMed:Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae). |
| PubMed:Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species. |
| PubMed:Chemical composition and larvicidal evaluation of Mentha, Salvia, and Melissa essential oils against the West Nile virus mosquito Culex pipiens. |
| PubMed:Composition and chemical variability of Mentha suaveolens ssp. suaveolens and M. suaveolens ssp. insularis from Corsica. |
| PubMed:Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils. |
| PubMed:Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice. |
| PubMed:Comparative analysis of the oil and supercritical CO2 extract of Ridolfia segetum (L.) Moris. |
| PubMed:Piperitenone oxide as toxic, repellent, and reproduction retardant toward malarial vector Anopheles stephensi (Diptera: Anophelinae). |
| PubMed:Composition of the essential oil of Mentha microphylla from the Gennargentu Mountains (Sardinia, Italy). |
| PubMed:Antibacterial and antifungal activity of essential oils of Mentha suaveolens. |
| PubMed:Activity of essential oils of three Micromeria species (Lamiaceae) against micromycetes and bacteria. |
| PubMed:Cardiovascular effects of the essential oil of Mentha x villosa and its main constituent, piperitenone oxide, in normotensive anaesthetised rats: role of the autonomic nervous system. |
| PubMed:Phytochemical study of Mentha longifolia of Morocco. |
| PubMed:Effects of piperitenone oxide on the intestinal smooth muscle of the guinea pig. |
| PubMed:Microbial transformations of some monoterpenoids and sesquiterpenoids. |
|
3D/inchi