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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 98.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.81500 to 0.82200 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 6.782 to 6.840
|
| Refractive Index: | 1.40700 to 1.41300 @ 20.00 °C.
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| Melting Point: | -9.00 to -8.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 114.00 to 115.00 °C. @ 749.00 mm Hg
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| Vapor Pressure: | 9.661000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 1.0 ( Air = 1 ) |
| Flash Point: | 93.00 °F. TCC ( 33.89 °C. )
|
| logP (o/w): | 1.210 |
| Soluble in: |
| | alcohol | | | water, 3.768e+004 mg/L @ 25 °C (est) | | | water, 5.15E+04 mg/L @ 25 °C (exp) |
| Similar Items:note |
| 2-pentanol |
| N-pentanol |
| isopentanol |
Organoleptic Properties:
| Odor Type: herbal |
| sweet herbal oily nutty |
| Odor Description:at 0.10 % in propylene glycol. sweet herbal oily nutty |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 10 - Flammable.
R 20 - Harmful by inhalation.
R 37 - Irritating to respiratory system.
R 66 - Repeated exposure may cause skin dryness or cracking.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
S 46 - If swallowed, seek medical advice immediately and show this container or label.
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| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1870 mg/kg
(Eder et al., 1982a)
intraperitoneal-rat LD50 1950 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 1, 1945.
oral-rat LD50 1870 mg/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
intraperitoneal-rat LDLo 1950 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 1, 1945.
|
| Dermal Toxicity: |
skin-rabbit LD50 2520 ul/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for 3-pentanol usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.19 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3900 (μg/person/day) |
| Threshold of Concern: | 1800 (μg/person/day) |
| Structure Class: | I |
| |
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| | average usage mg/kg | maximum usage mg/kg |
| Dairy products, excluding products of category 02.0 (01.0): | 7.00000 | 35.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 5.00000 | 25.00000 |
| Edible ices, including sherbet and sorbet (03.0): | 10.00000 | 50.00000 |
| Processed fruit (04.1): | 7.00000 | 35.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
| Confectionery (05.0): | 10.00000 | 50.00000 |
| Chewing gum (05.3): | - | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 5.00000 | 25.00000 |
| Bakery wares (07.0): | 10.00000 | 50.00000 |
| Meat and meat products, including poultry and game (08.0): | 2.00000 | 10.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 2.00000 | 10.00000 |
| Eggs and egg products (10.0): | - | - |
| Sweeteners, including honey (11.0): | - | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 5.00000 | 25.00000 |
| Foodstuffs intended for particular nutritional uses (13.0): | 10.00000 | 50.00000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 5.00000 | 25.00000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 50.00000 |
| Ready-to-eat savouries (15.0): | 20.00000 | 100.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
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Flavouring Group Evaluation 63 (FGE.63): Consideration of aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th meeting) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated by EFSA in FGE.07 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
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Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf
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Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
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Flavouring Group Evaluation 7, Revision 3 (FGE.07Rev3): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 7, Revision 4 (FGE.07Rev4): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5): saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf
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| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):584-02-1 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :11428 |
| National Institute of Allergy and Infectious Diseases:Data |
| WISER:UN 1105 |
| WGK Germany:1 |
| pentan-3-ol |
| Chemidplus:0000584021 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:584-02-1 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | diethyl carbinol | | | pentan-3-ol | | 3- | pentyl alcohol |
Articles:
| PubMed:Contribution of liver alcohol dehydrogenase to metabolism of alcohols in rats. |
| PubMed:Synthesis, characterization, and reactivity studies of a water-soluble bis(alkoxo)(carboxylato)-bridged diMn(III) complex modeling the active site in catalase. |
| PubMed:Field evaluation of the bacterial volatile derivative 3-pentanol in priming for induced resistance in pepper. |
| PubMed:Behavioral and electrophysiological responses of Aedes albopictus to certain acids and alcohols present in human skin emanations. |
| PubMed:Aroma enhancement and enzymolysis regulation of grape wine using β-glycosidase. |
| PubMed:Dislodgement effect of natural semiochemicals released by disturbed triatomines: a possible alternative monitoring tool. |
| PubMed:Ruthenium-catalyzed α-(hetero)arylation of saturated cyclic amines: reaction scope and mechanism. |
| PubMed:Two Volatile Organic Compounds Trigger Plant Self-Defense against a Bacterial Pathogen and a Sucking Insect in Cucumber under Open Field Conditions. |
| PubMed:Can volatile organic metabolites be used to simultaneously assess microbial and mite contamination level in cereal grains and coffee beans? |
| PubMed:Effect of release rate and enantiomeric composition on response to pheromones of Megaplatypus mutatus (Chapuis) in poplar plantations of Argentina and Italy. |
| PubMed:Electrophysiological and behavioral responses of male fall webworm moths (Hyphantria cunea) to Herbivory-induced mulberry (Morus alba) leaf volatiles. |
| PubMed:The role of the alcohol and carboxylic acid in directed ruthenium-catalyzed C(sp3)-H α-alkylation of cyclic amines. |
| PubMed:Synthesis of short-chain diols and unsaturated alcohols from secondary alcohol substrates by the Rieske nonheme mononuclear iron oxygenase MdpJ. |
| PubMed:The effect of alcohol structures on the interaction mode with the hexameric capsule of resorcin[4]arene. |
| PubMed:Paclobutrazol treatment as a potential strategy for higher seed and oil yield in field-grown Camelina sativa L. Crantz. |
| PubMed:Bacterial degradation of tert-amyl alcohol proceeds via hemiterpene 2-methyl-3-buten-2-ol by employing the tertiary alcohol desaturase function of the Rieske nonheme mononuclear iron oxygenase MdpJ. |
| PubMed:Stereoselective degradation of tebuconazole in rat liver microsomes. |
| PubMed:Fragrance material review on 1-phenyl-3-methyl-3-pentanol. |
| PubMed:Synthesis, characterization, and catalase activity of a water-soluble diMn(III) complex of a sulphonato-substituted Schiff base ligand: an efficient catalyst for H2O2 disproportionation. |
| PubMed:Sensory and physicochemical evolution of tropical cooked peeled shrimp inoculated by Brochothrix thermosphacta and Lactococcus piscium CNCM I-4031 during storage at 8°C. |
| PubMed:The critical behavior of the dielectric constant in the polar + polar binary liquid mixture nitromethane + 3-pentanol: an unusual sign of its critical amplitude in the one-phase region. |
| PubMed:Use of urine volatile organic compounds to discriminate tuberculosis patients from healthy subjects. |
| PubMed:Large heat capacity anomaly near the consolute point of the binary mixture nitromethane and 3-pentanol. |
| PubMed:Authentication of fattening diet of Iberian pigs according to their volatile compounds profile from raw subcutaneous fat. |
| PubMed:Bacterial diversity in paclobutrazol applied agricultural soils. |
| PubMed:Structural aspects in the dielectric properties of pentyl alcohols. |
| PubMed:Matrix effects on the photocatalytic oxidation of alcohols by [nBu4N]4W10O32 incorporated into sol-gel silica. |
| PubMed:Palladium-catalyzed reductive homocoupling of aromatic halides and oxidation of alcohols. |
| PubMed:New methodology for simultaneous volumetric and calorimetric measurements: direct determination of alpha(p) and C(p) for liquids under pressure. |
| PubMed:Behavioral and electrophysiological responses of Triatoma brasiliensis males to volatiles produced in the metasternal glands of females. |
| PubMed:Quantification of water and silanol species on various silicas by coupling IR spectroscopy and in-situ thermogravimetry. |
| PubMed:Application of a new statistical mechanical model for calculating Kirkwood factors in self associating liquid systems to alkanol + CCl4 mixtures. |
| PubMed:Synthesis, structure, and catalase-like activity of dimanganese(III) complexes of 1,5-bis[(2-hydroxy-5-X-benzyl)(2-pyridylmethyl)amino]pentan-3-ol (X = H, Br, OCH3). |
| PubMed:Sn-free Ni-catalyzed reductive coupling of glycosyl bromides with activated alkenes. |
| PubMed:3-pentanol: a new attractant present in volatile emissions from the ambrosia beetle, Megaplatypus mutatus. |
| PubMed:Atmospheric chemistry of 3-pentanol: kinetics, mechanisms, and products of Cl atom and OH radical initiated oxidation in the presence and absence of NOX. |
| PubMed:Iterative tandem catalysis of secondary diols and diesters to chiral polyesters. |
| PubMed:Solvent as a competitive inhibitor for Candida antarctica lipase B. |
| PubMed:Synthesis and application of a bidentate ligand based on decafluoro-3-phenyl-3-pentanol: steric effect of pentafluoroethyl groups on the stereomutation of O-equatorial C-apical spirophosphoranes. |
| PubMed:Heat capacity of associated systems. Experimental data and application of a two-state model to pure liquids and mixtures. |
| PubMed:Stereoselective degradation kinetics of tebuconazole in rabbits. |
| PubMed:Synthesis, structure and catalase-like activity of dimanganese(III) complexes of 1,5-bis(X-salicylidenamino)pentan-3-ol (X = 3- and 5-methyl). Influence of phenyl-ring substituents on catalytic activity. |
| PubMed:Chemical communication in Chagas disease vectors. Source, identity, and potential function of volatiles released by the metasternal and Brindley's glands of Triatoma infestans adults. |
| PubMed:New dimanganese(III) complexes of pentadentate (N2O3) Schiff base ligands with the [Mn2(mu-OAc)(mu-OR)2]3+ core: synthesis, characterization and mechanistic studies of H2O2 disproportionation. |
| PubMed:Occurrence of polyfunctional thiols in fresh lager beers. |
| PubMed:Synthesis of 9-[1-(1 -hydroxyethyl)-3-(phosphonomethoxy)propyl]adenine and prodrug as possible antiviral agents. |
| PubMed:Photostability studies for micellar liquid chromatographic determination of nifedipine in serum and urine samples. |
| PubMed:Kinetic resolution and chemoenzymatic dynamic kinetic resolution of functionalized gamma-hydroxy amides. |
| PubMed:A direct passive method for measuring water and contaminant fluxes in porous media. |
| PubMed:Synthesis, characterisation and catalase-like activity of dimanganese(III) complexes of 1,5-bis(5-X-salicylidenamino)pentan-3-ol (X=nitro and chloro). |
| PubMed:Conductor compounds of phenylpentane in Mycoleptodonoides aitchisonii mycelium enhance the release of dopamine from rat brain striatum slices. |
| PubMed:New approach to IR study of monomer-dimer self-association: 2,2-dimethyl-3-ethyl-3-pentanol in tetrachloroethylene as an example. |
| PubMed:Tetradecyltrimethylammonium bromide water-in-oil microemulsions: dependence of the minimum amount of alkanol required to produce a microemulsion with the alkanol and organic solvent topology. |
| PubMed:The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. |
| PubMed:Microemulsion electrokinetic chromatography for the analysis of green tea catechins: effect of the cosurfactant on the separation selectivity. |
| PubMed:Changes in the order of elution of some organic compounds in high-resolution gas chromatography on polar columns depending on the injection method and water content in the sample. |
| PubMed:Residual alcohol influence on NAPL saturation estimates based on partitioning tracers. |
| PubMed:Reduction in turgid water volume in jack pine, white spruce and black spruce in response to drought and paclobutrazol. |
| PubMed:Spectroscopic probing of the effect of alkanols on the properties of the head group region in reverse micelles of AOT-heptane-water. |
| PubMed:Catalysis and kinetics of hydrogen peroxide disproportionation by dinuclear manganese(III) complexes of 1,5-bis(salicylidenamino)pentan-3-ol and the 5-bromophenyl-substituted derivative. |
| PubMed:Novel antagonists of alcohol inhibition of l1-mediated cell adhesion: multiple mechanisms of action. |
| PubMed:Conformational studies by dynamic NMR. 88.(1) stereomutation processes in the diastereoisomers of a representative amino alcohol and related amide precursors. |
| PubMed:Synthesis, structure, and magnetic properties of tetranuclear cubane-like and chain-like iron(II) complexes based on the N(4)O pentadentate dinucleating ligand 1,5-bis[(2-pyridylmethyl)amino]pentan-3-ol. |
| PubMed:Formation of protoberberine-type alkaloids by the tubers of somatic embryo-derived plants of Corydalis yanhusuo. |
| PubMed:Catalysis by amino acid-derived tetracoordinate complexes: enantioselective addition of dialkylzincs to aliphatic and aromatic aldehydes. |
| PubMed:Short-range interactions within molecular complexes formed in supersonic beams: structural effects and chiral discrimination |
| PubMed:Utilization of fluorescein sodium salt for the indirect fluorimetric detection in micellar electrokinetic chromatography. |
| PubMed:Volatile composition of sunflower oil-in-water emulsions during initial lipid oxidation: influence of pH. |
| PubMed:High-performance liquid chromatographic assay detects pentamidine metabolism by Fisher rat liver microsomes. |
| PubMed:Effect of the hydration state of supports before lyophilization on subtilisin-A activity in organic media. |
| PubMed:Structural and Functional Models for the Dinuclear Copper Active Site in Catechol Oxidases: Syntheses, X-ray Crystal Structures, Magnetic and Spectral Properties, and X-ray Absorption Spectroscopic Studies in Solid State and in Solution. |
| PubMed:Study of the resolution of amino acids and aminoalcohols in organic solvents. |
| PubMed:Pseudo-ternary phase diagrams of lecithin-based microemulsions: influence of monoalkylphosphates. |
| PubMed:Enzymatic resolution of racemic amines in a continuous reactor in organic solvents. |
| PubMed:The effect of growth retardants on anthocyanin production in carrot cell suspension cultures. |
| PubMed:Metabolism of sodium nifurstyrenate, a veterinary antimicrobial nitrofuran, in animals and fish. |
| PubMed:Substrate specificity and stereoselectivity of horse liver alcohol dehydrogenase. Kinetic evaluation of binding and activation parameters controlling the catalytic cycles of unbranched, acyclic secondary alcohols and ketones as substrates of the native and active-site-specific Co(II)-substituted enzyme. |
| PubMed:[Metabolism and toxicity of n-pentane and isopentane]. |
| PubMed:Hydroxylation of pentamidine by rat liver microsomes. |
| PubMed:Synthesis of new (+-)-3,5-dihydroxypentyl nucleoside analogues from 1-amino-5-(benzyloxy)pentan-3-ol and their antiviral evaluation. |
| PubMed:Synthesis and biological activity of an azido derivative of paclobutrazol, an inhibitor of gibberellin biosynthesis. |
| PubMed:Effect of paclobutrazol on water stress-induced abscisic Acid in apple seedling leaves. |
| PubMed:Translocation of paclobutrazol, a gibberellin biosynthesis inhibitor, in apple seedlings. |
| PubMed:Purification and properties of a secondary alcohol dehydrogenase from the parasitic protozoan Tritrichomonas foetus. |
| PubMed:Effect of inhibitors of gibberellin biosynthesis on the induction of α-amylase in embryoless caryopses of Hordeum vulgare cv. Himalaya. |
| PubMed:Purification and characterization of a nicotinamide adenine dinucleotide-dependent secondary alcohol dehydrogenase from Candida boidinii. |
| PubMed:Experimental neurotoxicity and urinary metabolites of the C5-C7 aliphatic hydrocarbons used as glue solvents in shoe manufacture. |
| PubMed:Comparison of antimicrobial activity of nuclear-substituted aromatic esters of 5-dimethylamino-1-phenyl-3-pentanol and 3-dimethylamino-1-phenyl-1-propanol with related cyclic analogs. |
| PubMed:The specificities and configurations of ternary complexes of yeast and liver alcohol dehydrogenases. |
| PubMed:[Determination of 3-methyl-2-butanol and 3-pentanol in the products of alcohol fermentation]. |
| PubMed:Stimulation of tarsal receptors of the blowfly by aliphatic aldehydes and ketones. |
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3D/inchi