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CAS Number: 306-08-1

SMILES : O=C(O)Cc(ccc(O)c1OC)c1

CHEM : Benzeneacetic acid, 4-hydroxy-3-methoxy-

MOL FOR: C9 H10 O4

MOL WT : 182.18

------------------------------ EPI SUMMARY (v4.00) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.67 estimate) = 0.77

Log Kow (Exper. database match) = 0.33

Exper. Ref: LAHANN,TR ET AL. (1989)

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 338.85 (Adapted Stein & Brown method)

Melting Pt (deg C): 117.66 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 4.3E-006 (Modified Grain method)

VP (Pa, 25 deg C) : 0.000573 (Modified Grain method)

MP (exp database): 143.5 deg C

Subcooled liquid VP: 6.8E-005 mm Hg (25 deg C, Mod-Grain method)

: 0.00907 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.41):

Water Solubility at 25 deg C (mg/L): 6.973e+004

log Kow used: 0.33 (expkow database)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 1.1495e+005 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Phenols-acid

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 2.72E-013 atm-m3/mole (2.76E-008 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 1.478E-011 atm-m3/mole (1.498E-006 Pa-m3/mole)

VP: 4.3E-006 mm Hg (source: MPBPVP)

WS: 6.97E+004 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 0.33 (exp database)

Log Kaw used: -10.954 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 11.284

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 1.0359

Biowin2 (Non-Linear Model) : 0.9918

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 3.0846 (weeks )

Biowin4 (Primary Survey Model) : 4.0187 (days )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : 0.5802

Biowin6 (MITI Non-Linear Model): 0.6148

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): 0.7939

Ready Biodegradability Prediction: YES

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 0.00907 Pa (6.8E-005 mm Hg)

Log Koa (Koawin est ): 11.284

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 0.000331

Octanol/air (Koa) model: 0.0472

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 0.0118

Mackay model : 0.0258

Octanol/air (Koa) model: 0.791

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 31.9218 E-12 cm3/molecule-sec

Half-Life = 0.335 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 4.021 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Reaction With Nitrate Radicals May Be Important!

Fraction sorbed to airborne particulates (phi):

0.0188 (Junge-Pankow, Mackay avg)

0.791 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 24.83 L/kg (MCI method)

Log Koc: 1.395 (MCI method)

Koc : 3.639 L/kg (Kow method)

Log Koc: 0.561 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.00):

Log BCF from regression-based method = 0.500 (BCF = 3.162 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -1.6066 days (HL = 0.02474 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.002 (BCF = 1.006)

Log BAF Arnot-Gobas method (upper trophic) = 0.002 (BAF = 1.006)

log Kow used: 0.33 (expkow database)

Volatilization from Water:

Henry LC: 2.72E-013 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 2.905E+009 hours (1.211E+008 days)

Half-Life from Model Lake : 3.169E+010 hours (1.321E+009 days)

Removal In Wastewater Treatment:

Total removal: 1.86 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.76 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 5.56e-006 8.04 1000

Water 25.4 360 1000

Soil 74.5 720 1000

Sediment 0.0729 3.24e+003 0

Persistence Time: 685 hr

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