EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

triisopropanol amine
propan-2-ol, 1,1',1''-nitrilotris-

Supplier Sponsors

Name:1-[bis(2-hydroxypropyl)amino]propan-2-ol
CAS Number: 122-20-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:204-528-4
FDA UNII: W9EN9DLM98
Nikkaji Web:J3.616A
Beilstein Number:1071570
MDL:MFCD00004533
XlogP3-AA:-0.50 (est)
Molecular Weight:191.27097000
Formula:C9 H21 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:buffering agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FCN 337 Trilauryl phosphite View - notice
FCN 1024 Triisopropanolamine View - notice
FDA Mainterm (IAUFC):122-20-3 ; TRIISOPROPANOLAMINE
 
Physical Properties:
Appearance:white solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 45.00 °C. @ 760.00 mm Hg
Boiling Point: 305.00 °C. @ 760.00 mm Hg
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 0.073 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
 
Suppliers:
BASF
Triisopropanolamine
BOC Sciences
For experimental / research use only.
1,1,1-Nitrilotris-2-propanol 95%
Dow Chemical
DOW Specialty Amines - Isopropanolamines
Santa Cruz Biotechnology
For experimental / research use only.
Triisopropanolamine
Sigma-Aldrich: Aldrich
For experimental / research use only.
Triisopropanolamine 95%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LD50 1580 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

oral-mouse LD50 2520 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.

oral-rabbit LD50 11000 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.

oral-rat LD50 4730 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(7), Pg. 46, 1986.

Dermal Toxicity:
skin-mammal (species unspecified) LD50 > 1000 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(7), Pg. 46, 1986.

skin-rabbit LDLo 10 mL/kg
Union Carbide Data Sheet. Vol. 4/21/1967

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
buffering agents
Recommendation for triisopropanol amine usage levels up to:
 not for fragrance use.
 
Recommendation for triisopropanol amine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):122-20-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24730
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
1-[bis(2-hydroxypropyl)amino]propan-2-ol
Chemidplus:0000122203
EPA/NOAA CAMEO:hazardous materials
RTECS:122-20-3
 
References:
 1-[bis(2-hydroxypropyl)amino]propan-2-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:122-20-3
Pubchem (cid):24730
Pubchem (sid):134973705
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2922.19.5000
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•usepaopp pesticide code 004209; trade names: none listed. •grade: technical
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 buffering agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
tris(2-hydroxy-1-propyl)amine
tris(2-hydroxypropyl)amine
1-[bis(2-hydroxypropyl)amino]propan-2-ol
1,1',1''-nitrilotri-2-propanol
1,1',1''-nitrilotri(-2-propanol)
1,1',1''-nitrilotri(2-propanol)
1,1',1''-nitrilotripropan-2-ol
1,1',1''-nitrilotris (2-propanol)
1,1',1''-nitrilotris-2-propanol
1,1',1''-nitrilotris(2-propanol)
 propan-2-ol, 1,1',1''-nitrilotris-
2-propanol, 1,1',1''-nitrilotri-
2-propanol, 1,1',1''-nitrilotris-
tris(2-propanol)amine
 TIPA
 tri-2-propanolamine
 tri-iso-propanolamine
 triisopropanolamine
 
 
Notes:
None found
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