EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

glycolic acid
acetic acid, 2-hydroxy-

Supplier Sponsors

Name:2-hydroxyacetic acid
CAS Number: 79-14-1Picture of molecule3D/inchi
Other(deleted CASRN):259744-22-4
ECHA EINECS - REACH Pre-Reg:201-180-5
FDA UNII: 0WT12SX38S
Nikkaji Web:J1.494J
Beilstein Number:1209322
MDL:MFCD00004312
XlogP3:-1.10 (est)
Molecular Weight:76.05148000
Formula:C2 H4 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:buffering agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:glycolic acid
FDA Mainterm (IAUFC):79-14-1 ; GLYCOLIC ACID
 
Physical Properties:
Appearance:colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 79.50 °C. @ 760.00 mm Hg
Boiling Point: 265.57 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point: 264.00 °F. TCC ( 128.70 °C. ) (est)
logP (o/w): -1.204 (est)
Soluble in:
 alcohol
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Type: buttery
Odor Description:at 100.00 %. odorless very mild buttery
Luebke, William tgsc, (1996)
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
 
Suppliers:
Beijing Lys Chemicals
Glycolic acid
BOC Sciences
For experimental / research use only.
Hydroxyacetic Acid ultra pure crystals
Odor: characteristic
Use: Constituent of sugar cane juice.
Charkit Chemical
GLYCOLIC ACID 70%
Connect Chemicals
Glycolic acid 70% (cosmetic grade)
Odor: characteristic
Use: Glycolic Acid 70% (cosmetic grade) is the smallest molecule of the Alpha Hydroxy Acid. Due to its small size it is able to penetrate the skin, getting into the pores to clear out debris and unclog the pores. This stimulates new growth of skin and removal of old, dead, dull skin. Glycolic Acid 70% (cosmetic grade) is mainly used to improve the appearance and texture of the skin through chemical peel process. Once applied to the skin it breaks down the lipids that hold the dead skin cells on the surface, speeding their removal, resulting in an improved appearance with fewer spots, refined pores, and a more even skin tone that is more radiant.
Covalent Chemical
Glycolic Acid
ECSA Chemicals
GLYCOLIC ACID 70%
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Glentham Life Sciences
Glycolic acid
Penta International
GLYCOLIC ACID 70% TECHNICAL GRADE
Penta International
GLYCOLIC ACID 99% POWDER
Sigma-Aldrich
For experimental / research use only.
Glycolic Acid ReagentPlus®, 99%
Silver Fern Chemical
Glycolic Acid
Odor: characteristic
Use: Glycolic acid is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent. It is also used in adhesives and plastics. Glycolic acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
WholeChem
Glycolic acid
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-cat LD50 1000 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 656, 1986.

oral-guinea pig LD50 1920 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

oral-rat LD50 1950 mg/kg
GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LC50 7100 ug/m3/4H
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Inhalation Toxicology. Vol. 9, Pg. 435, 1997.

 
Safety in Use Information:
Category:
buffering agents
Recommendation for glycolic acid usage levels up to:
 not for fragrance use.
 
Recommendation for glycolic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

18th list of substances for food contact materials - Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food
View page or View pdf

Scientific Opinion on the safety evaluation of the substance glycolic acid for use in food contact materials
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):79-14-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :757
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:1
2-hydroxyacetic acid
Chemidplus:0000079141
RTECS:79-14-1
 
References:
 2-hydroxyacetic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:79-14-1
Pubchem (cid):757
Pubchem (sid):134971250
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C00160
HMDB (The Human Metabolome Database):HMDB00115
FooDB:FDB003298
YMDB (Yeast Metabolome Database):YMDB00807
Export Tariff Code:2918.19.9000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•grades: technical, 70% soln; pure crystals. avail commercially as 70% soln. •available commercially as either a 57% (hoechst) or a 70% (du pont) aqueous solution •clorox patch: active ingredient 1.5% glycolic acid. •x-men: active ingredients 3.070% glycolic acid, 0.180% alkyl dimethyl benzyl ammonium chloride (50%c14, 40%c12, 10%c16), 0.081% didecyl dimethyl ammonium chloride, 0.135% octyl decyl dimethyl ammonium chloride & 0.054% dioctyl dimethyl ammonium chloride. •show: active ingredient 11.185% glycolic acid. •dupont glyclean am: active ingredient 70% glycolic acid. •dupont bowl cleaner: active ingredient 9.5% glycolic acid. •dupont kleanit: active ingredient 5% glycolic acid.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 buffering agents
 
Occurrence (nature, food, other):note
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 currant black currant fruit
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 fennel plant
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 fennel root
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 grape leaf
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 lupine white lupine seed
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 onion bulb
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 parsley root
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 parsley seed
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 pea seed
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 rice
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 roselle flower
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 rosemary plant
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 soybean root
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 soybean seed
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 soybean sprout
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 sugar beets
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 sugar cane
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 tomato fruit
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Synonyms:
 acetic acid, 2-hydroxy-
 acetic acid, hydroxy-
 glycol acid
 glycolicacid
 glycollic acid
 GOA
2-hydroxyacetic acid
a-hydroxyacetic acid
2-hydroxyethanoic acid
 
 
Notes:
Found in sugar cane (Saccharum officinarum) Glycolic acid (or hydroxyacetic acid) is the smallest alpha-hydroxy acid (AHA). This colorless, odorless, and hygroscopic crystalline solid is highly soluble in water. It is used in various skin-care products. Glycolic acid is found in some sugar-crops. (Wikipedia)
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