EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ammonium citrate dibasic
diammonium 3-carboxy-3-hydroxypentanedioate

Supplier Sponsors

Name:diazanium 3-carboxy-3-hydroxypentanedioate
CAS Number: 3012-65-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:221-146-3
FDA UNII: N9BUG430K8
Beilstein Number:4925760
MDL:MFCD00013068
Molecular Weight:226.18598000
Formula:C6 H14 N2 O7
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:stabilizing agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1140 Ammonium citrate View - review
FDA Mainterm (SATF):3012-65-5 ; AMMONIUM CITRATE, DIBASIC
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.380 Xylene-formaldehyde resins condensed with 4,4'-isopropylidenediphenol-epichlorohydrin epoxy resins.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.390 Zinc-silicon dioxide matrix coatings.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1350 Ethylene-vinyl acetate copolymers.


FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS
Subpart B--Specific Prior-Sanctioned Food Ingredients
Sec. 181.29 Stabilizers.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1140 Ammonium citrate, dibasic.
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 309.00 to 310.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.000057 mmHg @ 25.00 °C. (est)
Vapor Density:1.8 ( Air = 1 )
Flash Point: 311.00 °F. TCC ( 155.00 °C. )
logP (o/w): -2.840
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 water, 5.00E+05 mg/L @ C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
chelating agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Diammonium citrate Purity >99%
ECSA Chemicals
DI-AMMONIUM HYDROGEN CITRATE RPE-ACS-FOR ANA
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Glentham Life Sciences
di-Ammonium hydrogen citrate
Indis NV
For experimental / research use only.
Ammonium Hydrogen Citrate
Jost Chemical
Ammonium Citrate Dibasic 25% Aqueous Solution
Jost Chemical
Ammonium Citrate Dibasic ACS Granular
Jost Chemical
Ammonium Citrate Dibasic FCC Granular
Jost Chemical
Ammonium Citrate Dibasic Technical Granular
Penta International
AMMONIUM CITRATE DIBASIC
Santa Cruz Biotechnology
For experimental / research use only.
Ammonium hydrogencitrate
Sigma-Aldrich
For experimental / research use only.
Ammonium citrate dibasic puriss., ≥98%
Universal Preserv-A-Chem Inc.
AMMONIUM CITRATE DIBASIC ACS
Odor: characteristic
Use: Used as a flavor enhancer and in non-alcoholic beverages.
 
Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/37 - Irritating to eyes and respiratory system.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
stabilizing agents
Recommendation for ammonium citrate dibasic usage levels up to:
 not for fragrance use.
 
Recommendation for ammonium citrate dibasic flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):3012-65-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :18171
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
diazanium 3-carboxy-3-hydroxypentanedioate
Chemidplus:0003012655
EPA/NOAA CAMEO:hazardous materials
RTECS:GE7573000 for cas# 3012-65-5
 
References:
 diazanium 3-carboxy-3-hydroxypentanedioate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:3012-65-5
Pubchem (cid):18171
Pubchem (sid):134981510
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
HMDB (The Human Metabolome Database):HMDB32172
FooDB:FDB008943
Export Tariff Code:2918.15.5000
FDA Listing of Food Additive Status:View
ChemSpider:View
Formulations/Preparations:
•grades or purity: reagent •diammonium citrate is marketed as granules or crystals.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ammonium citrate dibasic
 ammonium citrate, dibasic
 ammonium hydrogen citrate
 ammonium hydrogencitrate
 ammonium monohydrogen citrate
 ammonium monohydrogencitrate
 ammoniumcitratedibasic
 citric acid diammonium salt
 citric acid, diammonium salt
 diammonium 2-(carboxymethyl)-2-hydroxybutanedioate
 diammonium 2-(carboxymethyl)-2-hydroxysuccinate
 diammonium 2-hydroxy-1,2,3-propanetricarboxylate
 diammonium 3-carboxy-3-hydroxypentanedioate
 diammonium citrate
 diammonium hydrogen 2-hydroxypropane-1,2,3-tricarboxylate
 diammonium hydrogen citrate
 diazanium 3-carboxy-3-hydroxypentanedioate
2-hydroxy-1,2,3-propanetricarboxylic acid diammonium salt
2-hydroxy-1,2,3-propanetricarboxylic acid, diammonium salt
1,2,3-propanetricarboxylic acid, 2-hydroxy-, ammonium salt
1,2,3-propanetricarboxylic acid, 2-hydroxy-, diammonium salt
 

Articles:

PubMed:Injectability and mechanical properties of magnesium phosphate cements.
PubMed:A sialylation study of mouse brain gangliosides by MALDI a-TOF and o-TOF mass spectrometry.
PubMed:Effect of the addition of diammonium citrate to alpha-cyano-4-hydroxycinnamic acid (CHCA) matrix for the detection of phosphorylated peptide in phosphorylation reactions using cell and tissue lysates.
PubMed:Analytical procedure for the simultaneous voltammetric determination of trace metals in food and environmental matrices. Critical comparison with atomic absorption spectroscopic measurements.
PubMed:Development of a MALDI-TOF-MS method to identify and quantify butyrylcholinesterase inhibition resulting from exposure to organophosphate and carbamate pesticides.
PubMed:Detection of hypoxia-related proteins in medaka (Oryzias latipes) brain tissue by difference gel electrophoresis and de novo sequencing of 4-sulfophenyl isothiocyanate-derivatized peptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:MALDI analysis of oligonucleotides directly from montmorillonite.
PubMed:Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of 4-sulfophenyl isothiocyanate-derivatized peptides on AnchorChip sample supports using the sodium-tolerant matrix 2,4,6-trihydroxyacetophenone and diammonium citrate.
PubMed:Overlapping voltammetric peaks--an analytical procedure for simultaneous determination of trace metals. Application to food and environmental matrices.
PubMed:Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry.
PubMed:Improvement in the detection of low concentration protein digests on a MALDI TOF/TOF workstation by reducing alpha-cyano-4-hydroxycinnamic acid adduct ions.
PubMed:Analytical procedure for the simultaneous voltammetric determination of toxic metals in dialysis fluids.
PubMed:Effect of additives on electrokinetic properties of colloidal alumina suspension.
PubMed:Speciation of nickel in airborne particulate matter by means of sequential extraction in a micro flow system and determination by graphite furnace atomic absorption spectrometry and inductively coupled plasma mass spectrometry.
PubMed:Adverse effects of excess DL-methionine in calves with different body weights.
PubMed:Absence of limiting amino acids in calves fed a corn and soybean meal diet past three months of age.
PubMed:Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts.
PubMed:Matrix-assisted laser desorption/ionisation mass spectrometry of transfer ribonucleic acids isolated from yeast.
PubMed:Correlation of biological value of feed phosphates with their solubility in water, dilute hydrogen chloride, dilute citric acid, and neutral ammonium citrate.
PubMed:Utilization of dietary diammonium citrate by germ-free chicks.
PubMed:Effect of chemicals on fungal alpha-amylase activity.
PubMed:Production of succinic Acid from citric Acid and related acids by lactobacillus strains.
PubMed:15N transfer from 15N-urea and 15N-diammonium citrate into tissue proteins in normal cats fed with an optimal protein diet.
PubMed:Antagonism of arginine by excess dietary lysine in the growing dog.
PubMed:The effects of high dietary protein and nitrogen levels on the preformed methyl group requirement and methionine-induced growth depression in chicks.
PubMed:Incorporation of nitrogen-15 from dietary [15N] diammonium citrate into amino acids of liver and muscle proteins in germfree and specific-pathogen-free neonatal pigs.
PubMed:Diammonium citrate addition to a diet restricted non-essential amino acids for young pigs.
PubMed:Role of intestinal flora on incorporation of 15N from dietary, 15N-urea, and 15N-diammonium citrate into tissue proteins in pigs.
PubMed:Effects of dietary histidine and arginine on plasma amino acid and urea concentrations of men fed a low nitrogen diet.
PubMed:Effects of dietary histidine and arginine on nitrogen retention of men.
PubMed:The use of growth and liver aspartate aminotransferase to assess the effect of source of non-essential nitrogen on pyridoxine depletion, repletion and requirements of chicks.
PubMed:Is L-glutamic acid nutritionally a dispensable amino acid for the young chick?
PubMed:Nonprotein nitrogen for growing chickens.
PubMed:Growth inhibition of broilers by diammonium citrate.
PubMed:Egg production responses of Coturnix quail to dietary additions of nitrogen in the form of amino acids, diammonium citrate and intact protein.
PubMed:Comparison of urea and diammonium citrate as sources of nonspecific nigrogen for human adults.
PubMed:Effect of urea and diammonium citrate on fecal components of chicken hens.
PubMed:Enzyme studies with the livers of chicks fed semi-synthetic diets containing crystalline amino acids and diammonium citrate.
PubMed:Effects on chick growth of adding glycine, proline, glutamic acid or diammonium citrate to diets containing crystalline essential amino acids.
PubMed:Diammonium citrate and diammonium phosphate as sources of dietary nitrogen for growing-finishing swine.
PubMed:Some effects of nicotinamide, diammonium citrate and urea as supplements to low-protein diets.
PubMed:Diammonium citrate and diammonium phosphate as sources of dietary nitrogen for growing-finishing swine.
 
Notes:
Used as a food additive [EAFUS]
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