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Category:food contact substances for use only as components of articles intended for repeated use
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.72400 to 0.73000 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 6.024 to 6.074
|
| Refractive Index: | 1.39500 to 1.40100 @ 20.00 °C.
|
| Melting Point: | -115.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 88.80 to 89.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 56.054001 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 3.5 ( Air = 1 ) |
| Flash Point: | 20.00 °F. TCC ( -6.67 °C. )
|
| logP (o/w): | 1.450 |
| Soluble in: |
| | alcohol | | | water, 6.826e+004 mg/L @ 25 °C (est) | | | water, 7.37E+04 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor Type: fishy |
| ammoniacal fishy |
| Odor Description:at 0.01 % in propylene glycol. ammoniacal fishy |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | C - Corrosive. |
R 12 - Extremely flammable.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R 35 - Causes severe burns.
S 03 - Keep in cool place.
S 16 - Keep away from sources of ignition - No Smoking.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 29 - Do not empty into drains.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
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| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 460 mg/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
intraperitoneal-rat LD50 75 mg/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
oral-mouse LD50 546 mg/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
intraperitoneal-mouse LD50 405 mg/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
gavage-rat LD50 [sex: M] < 182.30 mg/kg
(Myers & Ballantyne, 1997)
intraperitoneal-mouse LD50 405 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
oral-mouse LD50 546 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Hygiene and Sanitation Vol. 30(7-9), Pg. 351, 1965.
intraperitoneal-rat LDLo 75 mg/kg
Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.
|
| Dermal Toxicity: |
skin-rabbit LD50 570 ul/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
|
| Inhalation Toxicity: |
inhalation-guinea pig LCLo 1000 ppm/4H
Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 2, 1948.
inhalation-human TCLo 6500 ug/m3/4H
SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE
SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Occupational and Environmental Medicine. Vol. 56, Pg. 1, 1999.
inhalation-human TCLo 12 mg/m3/11W-C
SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE
International Archives of Occupational and Environmental Health. Vol. 57, Pg. 297, 1986.
inhalation-human TCLo 20 mg/m3/8H
SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE
Weisheng Dulixue Zazhi. Journal of Health Toxicology. Vol. 4, Pg. 45, 1990.
inhalation-mammal (species unspecified) LC50 6000 mg/m3
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
inhalation-mouse LC50 6000 mg/m3
LIVER: FATTY LIVER DEGERATION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 56, 1965.
inhalation-rat LCLo 1000 ppm/4H
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
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Safety in Use Information:
| Category: | | food contact substances for use only as components of articles intended for repeated use |
| Recommendation for triethyl amine usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.073 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.90 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 340 (μg/person/day) |
| Threshold of Concern: | 1800 (μg/person/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 22 |
| Click here to view publication 22 |
| | average usual ppm | average maximum ppm |
| baked goods: | 2.00000 | 10.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | 0.20000 | 1.00000 |
| cheese: | 0.40000 | 2.00000 |
| chewing gum: | - | - |
| condiments / relishes: | 0.10000 | 0.50000 |
| confectionery froastings: | 1.00000 | 5.00000 |
| egg products: | - | - |
| fats / oils: | 0.10000 | 0.50000 |
| fish products: | 0.20000 | 1.00000 |
| frozen dairy: | 0.40000 | 2.00000 |
| fruit ices: | 0.40000 | 2.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | 0.10000 | 0.50000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | 0.20000 | 1.00000 |
| milk products: | 0.40000 | 2.00000 |
| nut products: | - | - |
| other grains: | 0.20000 | 1.00000 |
| poultry: | 0.20000 | 1.00000 |
| processed fruits: | 0.40000 | 2.00000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | 0.10000 | 0.50000 |
| snack foods: | 1.00000 | 5.00000 |
| soft candy: | - | - |
| soups: | 0.10000 | 0.50000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
| |
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| | average usage mg/kg | maximum usage mg/kg |
| Dairy products, excluding products of category 02.0 (01.0): | 0.40000 | 2.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 0.10000 | 0.50000 |
| Edible ices, including sherbet and sorbet (03.0): | 0.40000 | 2.00000 |
| Processed fruit (04.1): | 0.40000 | 2.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
| Confectionery (05.0): | 1.00000 | 5.00000 |
| Chewing gum (05.3): | - | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 0.20000 | 1.00000 |
| Bakery wares (07.0): | 2.00000 | 10.00000 |
| Meat and meat products, including poultry and game (08.0): | 0.20000 | 1.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.20000 | 1.00000 |
| Eggs and egg products (10.0): | - | - |
| Sweeteners, including honey (11.0): | - | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 0.10000 | 0.50000 |
| Foodstuffs intended for particular nutritional uses (13.0): | 0.20000 | 1.00000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | - | - |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 1.00000 | 5.00000 |
| Ready-to-eat savouries (15.0): | 1.00000 | 5.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.20000 | 1.00000 |
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| ( | diethyl amino) ethane | | N,N- | diethyl ethanamine | | ( | diethylamino)ethane | | | diethylaminoethane | | N,N- | diethylethanamine | | | ethanamine, N,N-diethyl- | | | triethylamine | | N,N,N- | triethylamine |
Articles:
| Info:aliphatic and aromatic amines and amides derivatives |
| PubMed:Simultaneous determination of tylosin and josamycin residues in muscles, liver, eggs and milk by MLC with a monolithic column and time-programmed UV detection: application to baby food and formulae. |
| PubMed:An eco-friendly, quick and cost-effective method for the quantification of acrylamide in cereal-based baby foods. |
| PubMed:Isotopic variants of light and heavy L-pyroglutamic acid succinimidyl esters as the derivatization reagents for DL-amino acid chiral metabolomics identification by liquid chromatography and electrospray ionization mass spectrometry. |
| PubMed:Phenylalanine functionalized zwitterionic monolith for hydrophobic interaction electrochromatography. |
| PubMed:Application of pH-zone-refining countercurrent chromatography for the separation of indole alkaloids from Aspidosperma rigidum Rusby. |
| PubMed:Spectrophotometric and chromatographic assessment of contributions of carotenoids and chlorophylls to the total antioxidant capacities of plant foods. |
| PubMed:Forced degradation and impurity profiling: recent trends in analytical perspectives. |
| PubMed:Rapid resolution liquid chromatography method development and validation for simultaneous determination of homocysteine, vitamins B(6), B(9), and B(12) in human serum. |
| PubMed:Biotinylation of a propargylated cyclic (3'-5') diguanylic acid and of its mono-6-thioated analog under "click" conditions. |
| PubMed:[Simultaneous determination of nine heterocyclic aromatic amines in mutton products by solid phase extraction-high performance liquid chromatography]. |
| PubMed:Determination of 2-methylimidazole and 4-methylimidazole in caramel colors by capillary electrophoresis. |
| PubMed:A multiresidual method based on ion-exchange chromatography with conductivity detection for the determination of biogenic amines in food and beverages. |
| PubMed:Study on a new synthesis approach of glyphosate. |
| PubMed:[Molecularly-imprinted solid phase extraction coupled with high performance liquid chromatography for the determination of ractopamine in feed samples]. |
| PubMed:Simultaneous determination of four biogenic and three volatile amines in anchovy by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry. |
| PubMed:One-pot formation of aromatic tetraurea macrocycles. |
| PubMed:Tosylated and azidated inulins as key substrates for further chemical modifications to access inulin-based advanced materials: an inulin-based glycocluster. |
| PubMed:[Determination of imidocarb residue in swine tissues by high performance liquid chromatography]. |
| PubMed:Improved solvent extraction procedure and high-performance liquid chromatography-evaporative light-scattering detector method for analysis of polar lipids from dairy materials. |
| PubMed:Determination of catechins in green tea infusions by reduced flow micellar electrokinetic chromatography. |
| PubMed:Simultaneous determination of thiamphenicol, florfenicol and florfenicol amine in eggs by reversed-phase high-performance liquid chromatography with fluorescence detection. |
| PubMed:A new high-performance liquid chromatographic method with evaporative light scattering detector for the analysis of phospholipids. Application to Iberian pig subcutaneous fat. |
| PubMed:[Simultaneous analysis of 4 non-steroidal anti-inflammatory drug residues in mutton muscle using high performance liquid chromatography assisted by ultrasonic-microwave extraction]. |
| PubMed:Screening of non-polar heterocyclic amines in urine by microextraction in packed sorbent-fluorimetric detection and confirmation by capillary liquid chromatography. |
| PubMed:Quinolones control in milk and eggs samples by liquid chromatography using a surfactant-mediated mobile phase. |
| PubMed:Homogeneous esterification of poplar wood in an ionic liquid under mild conditions: characterization and properties. |
| PubMed:Screening and selection of high carotenoid producing in vitro tomato cell culture lines for [13C]-carotenoid production. |
| PubMed:Preparative separation of alkaloids from Nelumbo nucifera leaves by conventional and pH-zone-refining counter-current chromatography. |
| PubMed:Refined methodology for the determination of neonicotinoid pesticides and their metabolites in honey bees and bee products by liquid chromatography-tandem mass spectrometry (LC-MS/MS). |
| PubMed:Suitability of ionic liquids as mobile-phase additives in HPLC with fluorescence and UV detection for the determination of heterocyclic aromatic amines. |
| PubMed:[Simultaneous determination of tetracyclines, sulfonamides and quinolones residues in chicken livers by ultra performance liquid chromatography-tandem mass spectrometry]. |
| PubMed:Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection. |
| PubMed:Herbicide treatments alter carotenoid profiles for 14C tracer production from tomato ( Solanum lycopersicum cv. VFNT cherry) cell cultures. |
| PubMed:Analysis of aminoglycoside residues in bovine milk by liquid chromatography electrospray ion trap mass spectrometry after derivatization with phenyl isocyanate. |
| PubMed:Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety. |
| PubMed:Ionic liquids as desorption solvents and memory effect suppressors in heterocyclic aromatic amines determination by SPME-HPLC fluorescence. |
| PubMed:Determination of sulphonated azo dyes in food by ion-pair liquid chromatography with photodiode array and electrospray mass spectrometry detection. |
| PubMed:High-performance liquid chromatography analysis methods developed for quantifying enzymatic esterification of flavonoids in ionic liquids. |
| PubMed:Impaired olfaction in mice lacking aquaporin-4 water channels. |
| PubMed:Studies of the lauroylation of wheat straw hemicelluloses under heating. |
| PubMed:A new electrochemiluminescent detection system equipped with an electrically heated carbon paste electrode for CE. |
| PubMed:Monitoring of fluoroquinolone residual levels in chicken eggs by microbiological assay and confirmation by liquid chromatography. |
| PubMed:Use of metabolic stimulators and inhibitors for enhanced production of beta-carotene and lycopene by Blakeslea trispora NRRL 2895 and 2896. |
| PubMed:Separation of intact plasmalogens and all other phospholipids by a single run of high-performance liquid chromatography. |
| PubMed:Development of a new method for analysis of Sudan dyes by pressurized CEC with amperometric detection. |
| PubMed:The derivatisation of avermectins and milbemycins in milk: new insights and improvement of the procedure. |
| PubMed:[Determination of acrylamide in foods by gas chromatography-mass spectrometry]. |
| PubMed:Positive and negative electrospray LC-MS-MS methods for quantitation of the antiparasitic endectocide drugs, abamectin, doramectin, emamectin, eprinomectin, ivermectin, moxidectin and selamectin in milk. |
| PubMed:Ion chromatography-atmospheric pressure chemical ionization mass spectrometry for the determination of trace chlorophenols in clam tissues. |
| PubMed:Rapid separation and determination of carbamate insecticides using isocratic elution pressurized capillary electrochromatography. |
| PubMed:The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes. |
| PubMed:Separation and determination of seven fluoroquinolones by pressurized capillary electrochromatography. |
| PubMed:Monocyclic carotenoid biosynthetic pathway in the yeast Phaffia rhodozyma (Xanthophyllomyces dendrorhous). |
| PubMed:Pressurized liquid extraction-capillary electrophoresis-mass spectrometry for the analysis of polar antioxidants in rosemary extracts. |
| PubMed:Additive impairment of the barrier function and irritation by biogenic amines and sodium lauryl sulphate: a controlled in vivo tandem irritation study. |
| PubMed:Identification and estimation of the levo isomer in raw materials and finished products containing atropine and/or hyoscyamine. |
| PubMed:HPLC enantioseparation of potential beta-blockers of the aryloxyaminopropanol type. Study of the mechanism of enantioseparation, Part VIII. |
| PubMed:New solvent systems for thin-layer chromatographic determination of nine biogenic amines in fish and squid. |
| PubMed:Study of the mechanism of enantioseparation part VI: thermodynamic study of HPLC separation of some enantiomers of phenylcarbamic acid derivatives on a (S,S) Whelk-O 1 column. |
| PubMed:A simple and rapid spectrophotometric method for determination of thiophanate-methyl in commercial formulations and its residues in foodstuffs. |
| PubMed:Determination of the rat tissue partitioning of endotoxin in vitro for physiologically-based pharmacokinetic (PBPK) modeling. |
| PubMed:Liquid chromatography-hydride generation-atomic absorption spectrometry for the speciation of tin in seafoods. |
| PubMed:Chemical and enzymatic transacylation of amide-linked FA of buttermilk gangliosides. |
| PubMed:A routine high-performance liquid chromatography method for carotenoid determination in ultrafrozen orange juices. |
| PubMed:Determination of acrylamide in foods by GC/MS using 13C-labeled acrylamide as an internal standard. |
| PubMed:[Simultaneous analysis of four diuretic drugs by HPLC and its application to health food supplements advertising weight reduction]. |
| PubMed:A psychophysical study of the relationship between temporal processing in odor mixtures and transduction pathways. |
| PubMed:Capillary electrophoresis of high-molecular chitosan: the natural carbohydrate biopolymer. |
| PubMed:Influence of incubation temperature on the behavior of triethylamine-extractable glyphosate (N-phosphonomethylglycine) in four soils. |
| PubMed:Characterization and esterification of hemicelluloses from rye straw. |
| PubMed:The analysis of beta-agonists by packed-column supercritical fluid chromatography with ultra-violet and atmospheric pressure chemical ionisation mass spectrometric detection. |
| PubMed:Isolation and identification of process impurities in trimethoprim drug substance by high-performance liquid chromatography, atmospheric pressure chemical ionization liquid chromatography/mass spectrometry and nuclear magnetic resonance spectroscopy. |
| PubMed:Temporal processing of odor mixtures reveals that identification of components takes precedence over temporal information in olfactory memory. |
| PubMed:[Multiplicity of sulfotransferases]. |
| PubMed:Determination of water-soluble vitamins in infant milk by high-performance liquid chromatography. |
| PubMed:Migration studies from paper and board food packaging materials. Part 2. Survey for residues of dialkylamino benzophenone UV-cure ink photoinitiators. |
| PubMed:Development of a HPLC method for the simultaneous determination of several B-vitamins and ascorbic acid. |
| PubMed:Significance of mobile phase composition in enantioseparation of chiral drugs by HPLC on a cellulose-based chiral stationary phase. |
| PubMed:High-performance liquid chromatographic method for the determination of the anthelmintic nitroxynil in cattle muscle tissue with on-line anion-exchange clean-up. |
| PubMed:Dibasic amines as competitive ions improve the resolution between polyanionic nucleotides. |
| PubMed:Synthesis of oligophosphoseryl sequences occurring in casein. Identification of beta-elimination during phosphorylation. |
| PubMed:Liquid chromatographic determination of hydralazine in human plasma with 2-hydroxy-1-naphthaldehyde pre-column derivatization. |
| PubMed:Mutagenicity of pyrolysates from guanidine, ureide, secondary amines and polyamines found by the Salmonella/mammalian-microsome test. |
| PubMed:[Migration behavior and toxicology of methyltin stabilizers]. |
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3D/inchi