| Name: | calcium;(2S,3S,4S,5S,6R)-6-[(2R,3S,4R,5S,6R)-2-carboxy-6-[(2R,3S,4R,5S,6R)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydro |
| CAS Number: | 9005-35-0 |  3D/inchi
|
| Other(deleted CASRN): | 37228-92-5 |
| FDA UNII: | 8P20S56HZI |
| MDL: | MFCD00143567 |
| Molecular Weight: | 584.45208000 |
| Formula: | C18 H24 Ca O19 |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) |
Category:thickeners, gelling agents, stabalizers and emulsifiers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
| Odor Strength:none |
| Odor Description:at 100.00 %. odorless |
| Taste Description: tasteless |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | None - None found. |
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Acute toxicity, Oral (Category 4), H302
Acute toxicity, dermal (Category 4), H312
Skin irritation (Category 2), H315
Eye irritation (Category 2A), H319
Acute toxicity, Inhalation (Category 4), H332
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
|
| GHS Label elements, including precautionary statements |
| |
| Pictogram |  |
| |
| Signal word | Warning |
| Hazard statement(s) |
H302 - Harmful if swallowed
H312 - Harmful in contact with skin
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H332 - Harmful if inhaled
H335 - May cause respiratory irritation
|
| Precautionary statement(s) |
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P501 - Dispose of contents/ container to an approved waste disposal plant.
|
| Oral/Parenteral Toxicity: |
intraperitoneal-rat LD50 1407 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 381, 1974.
intravenous-rat LD50 64 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 381, 1974.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | thickeners, gelling agents, stabalizers and emulsifiers |
| Recommendation for calcium alginate usage levels up to: | | | not for fragrance use.
|
| |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | 70.00000 | 200.00000 |
| beverages(nonalcoholic): | - | 340.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | 5200.00000 |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 1000.00000 |
| fruit ices: | - | 1000.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 1000.00000 |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Re-evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400–E 404) as food additives
View page or View pdf
|
| ClinicalTrials.gov:search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):9005-35-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :44630049 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| calcium;(2S,3S,4S,5S,6R)-6-[(2R,3S,4R,5S,6R)-2-carboxy-6-[(2R,3S,4R,5S,6R)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydro |
| Chemidplus:0009005350 |
| RTECS:AZ5810000 for cas# 9005-35-0 |
References:
| | calcium;(2S,3S,4S,5S,6R)-6-[(2R,3S,4R,5S,6R)-2-carboxy-6-[(2R,3S,4R,5S,6R)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydro |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 9005-35-0 |
| Pubchem (cid): | 44630049 |
| Pubchem (sid): | 135343737 |
Other Information:
Potential Blenders and core components note
Potential Uses:
| | binding agents |
| | emulsifying agents |
| | film formers |
| | gel forming agents |
| | viscosity controlling agents |
Occurrence (nature, food, other): note
Synonyms:
| | alginic acid calcium salt | | | alginic acid, calcium salt | | | calginat | | | calginate | | | combinace | | | kalrostat | | | kaltostat |
Articles:
| PubMed:Encapsulation of liquid smoke flavoring in ca-alginate and ca-alginate-chitosan beads. |
| PubMed:Proteolysis, volatile compounds, and sensory evaluation in Hispánico cheese manufactured with the addition of a thermophilic adjunct culture, nisin, and calcium alginate-nisin microparticles. |
| PubMed:Microencapsulation of Probiotics by Calcium Alginate-gelatinized Starch with Chitosan Coating and Evaluation of Survival in Simulated Human Gastro-intestinal Condition. |
| PubMed:l-Theanine Synthesis Using γ-Glutamyl Transpeptidase from Bacillus licheniformis ER-15. |
| PubMed:Ion exchange kinetics of magnetic alginate ferrogel beads produced by external gelation. |
| PubMed:Comparison of selected physico-chemical properties of calcium alginate films prepared by two different methods. |
| PubMed:Bioproduction of 4-vinylphenol from corn cob alkaline hydrolyzate in two-phase extractive fermentation using free or immobilized recombinant E. coli expressing pad gene. |
| PubMed:Microstructural, mechanical and mass transport properties of isotropic and capillary alginate gels. |
| PubMed:Combined of ultrasound irradiation with high hydrostatic pressure (US/HHP) as a new method to improve immobilization of dextranase onto alginate gel. |
| PubMed:Characterization of core-shell calcium-alginate macrocapsules fabricated by electro-coextrusion. |
| PubMed:Encapsulation of liquid smoke flavoring in ca-alginate and ca-alginate-chitosan beads. |
| PubMed:Levan production by Zymomonas mobilis in batch and continuous fermentation systems. |
| PubMed:Release of yerba mate antioxidants from corn starch-alginate capsules as affected by structure. |
| PubMed:Hydrolysis of soybean isoflavones by Debaryomyces hansenii UFV-1 immobilised cells and free β-glucosidase. |
| PubMed:Immobilized Rhodotorula mucilaginosa: a novel urethanase-producing strain for degrading ethyl carbamate. |
| PubMed:Immobilization of tomato (Lycopersicon esculentum) pectinmethylesterase in calcium alginate beads and its application in fruit juice clarification. |
| PubMed:Psychrotrophic Streptomyces spp. cells immobilisation in alginate microspheres produced by emulsification-internal gelation. |
| PubMed:Investigation into feed preparation for regulatory fish metabolism studies. |
| PubMed:Microencapsulation of tannic acid for oral administration to inhibit carbohydrate digestion in the gastrointestinal tract. |
| PubMed:Degradation of complex carbohydrate: immobilization of pectinase from Bacillus licheniformis KIBGE-IB21 using calcium alginate as a support. |
| PubMed:Ultrasound-assisted dextranase entrapment onto Ca-alginate gel beads. |
| PubMed:Alginate enhances excretion and reduces absorption of strontium and cesium in rats. |
| PubMed:Enhancing isomaltulose production by recombinant Escherichia coli producing sucrose isomerase: culture medium optimization containing agricultural wastes and cell immobilization. |
| PubMed:Biocatalytic anti-Prelog stereoselective reduction of ethyl acetoacetate catalyzed by whole cells of Acetobacter sp. CCTCC M209061. |
| PubMed:Development of an antimicrobial sachet containing encapsulated allyl isothiocyanate to inactivate Escherichia coli O157:H7 on spinach leaves. |
| PubMed:Stability of free and encapsulated Lactobacillus acidophilus ATCC 4356 in yogurt and in an artificial human gastric digestion system. |
| PubMed:Glucose oxidase-mediated gelation: a simple test to detect glucose in food products. |
| PubMed:Mechanical properties of calcium alginate fibers produced with a microfluidic device. |
| PubMed:The release rate of curcumin from calcium alginate beads regulated by food emulsifiers. |
| PubMed:Effects of process variables on the encapsulation of oil in ca-alginate capsules using an inverse gelation technique. |
| PubMed:Application of immobilized cell preparation obtained from biomass of Gluconacetobacter xylinus bacteria in biotransformation of glycerol to dihydroxyacetone. |
| PubMed:Immobilised Sarawak Malaysia yeast cells for production of bioethanol. |
| PubMed:Encapsulation of thyme (Thymus serpyllum L.) aqueous extract in calcium alginate beads. |
| PubMed:Catalytical Properties of Free and Immobilized Aspergillus niger Tannase. |
| PubMed:Emulsion properties of pork myofibrillar protein in combination with microbial transglutaminase and calcium alginate under various pH conditions. |
| PubMed:Immobilization of glucose oxidase in alginate-chitosan microcapsules. |
| PubMed:Encapsulation of astaxanthin-rich Xanthophyllomyces dendrorhous for antioxidant delivery. |
| PubMed:Impact of microencapsulated peptidase (Aspergillus oryzae) on cheddar cheese proteolysis and its biologically active peptide profile. |
| PubMed:Selection of non-conventional yeasts and their use in immobilized form for the bioremediation of olive oil mill wastewaters. |
| PubMed:Enzymatic synthesis of cholecalciferol glycosides using β-glucosidase from sweet almond. |
| PubMed:Microencapsulation of a probiotic and prebiotic in alginate-chitosan capsules improves survival in simulated gastro-intestinal conditions. |
| PubMed:Enhanced degradation of phenol by Pseudomonas sp. CP4 entrapped in agar and calcium alginate beads in batch and continuous processes. |
| PubMed:Effect of concentration and substrate flow rate on isomaltulose production from sucrose by Erwinia sp. cells immobilized in calcium-alginate using packed bed reactor. |
| PubMed:Effect of homogenization techniques on reducing the size of microcapsules and the survival of probiotic bacteria therein. |
| PubMed:Fabrication of microparticle protein delivery systems based on calcium alginate. |
| PubMed:Modeling of chromium (VI) biosorption by immobilized Spirulina platensis in packed column. |
| PubMed:Immobilization of a thermostable alpha-amylase by covalent binding to an alginate matrix increases high temperature usability. |
| PubMed:Management of chronic pressure ulcers: an evidence-based analysis. |
| PubMed:Microencapsulation of Lactobacillus plantarum spp in an alginate matrix coated with whey proteins. |
| PubMed:Ascorbic acid retaining using a new calcium alginate-Capsul based edible film. |
| PubMed:Control of Listeria monocytogenes and Salmonella anatum on the surface of smoked salmon coated with calcium alginate coating containing oyster lysozyme and nisin. |
| PubMed:Multiple-channel emulsion chips utilizing pneumatic choppers for biotechnology applications. |
| PubMed:Reexamining the egg-box model in calcium-alginate gels with X-ray diffraction. |
| PubMed:Suitability of pea starch and calcium alginate as antimicrobial coatings on chicken skin. |
| PubMed:Production of high hydroxytyrosol yields via tyrosol conversion by Pseudomonas aeruginosa immobilized resting cells. |
| PubMed:Removal of high phenol concentrations with adapted activated sludge in suspended form and entrapped in calcium alginate /cross-linked poly(N-vinyl pyrrolidone) hydrogels. |
| PubMed:Microfabricated airflow nozzle for microencapsulation of living cells into 150 micrometer microcapsules. |
| PubMed:Removable colored coatings based on calcium alginate hydrogels. |
| PubMed:Pre-treatment of high oil and grease pet food industrial wastewaters using immobilized lipase hydrolyzation. |
| PubMed:Citric acid prolongs the gastro-retention of a floating dosage form and increases bioavailability of riboflavin in the fasted state. |
| PubMed:The use of citric acid to prolong the in vivo gastro-retention of a floating dosage form in the fasted state. |
| PubMed:Formation of calcium alginate gel capsules: influence of sodium alginate and CaCl2 concentration on gelation kinetics. |
| PubMed:[The usage of food supplement to on the basis of calcium alginate for correction of liver infringements at virus hepatitis]. |
| PubMed:Size control of calcium alginate beads containing living cells using micro-nozzle array. |
| PubMed:Survival of freeze-dried Lactobacillus bulgaricus KFRI 673 in chitosan-coated calcium alginate microparticles. |
| PubMed:Improved quantitative recovery of Listeria monocytogenes from stainless steel surfaces using a one-ply composite tissue. |
| PubMed:Production of lipase in a fermentor using a mutant strain of Corynebacterium species: its partial purification and immobilization. |
| PubMed:Evaluation of calcium-alginate gel as an artificial diet medium for bioassays on common cutworms. |
| PubMed:Antimicrobial potential of immobilized Lactococcus lactis subsp. lactis ATCC 11454 against selected bacteria. |
| PubMed:Calcium-alginate coated, whey protein-based microspheres: preparation, some properties and opportunities. |
| PubMed:Proteolysis, volatile compounds, and sensory evaluation in Hispánico cheese manufactured with the addition of a thermophilic adjunct culture, nisin, and calcium alginate-nisin microparticles. |
| PubMed:Calcium alginate gel as encapsulation matrix for coimmobilized enzyme systems. |
| PubMed:Chiral resolution function with immobilized food proteins. |
| PubMed:Evaluation of a high temperature immobilised enzyme reactor for production of non-reducing oligosaccharides. |
| PubMed:Process for producing the potential food ingredient DFA III from inulin: screening, genetic engineering, fermentation and immobilisation of inulase II. |
| PubMed:Phase separation in calcium alginate gels. |
| PubMed:Production of beta-glucosidase using immobilised Piromyces sp. KSX1 and Orpinomyces sp. 478P1 in repeat-batch culture. |
| PubMed:Microencapsulation of probiotic bacteria: technology and potential applications. |
| PubMed:[Relationship between biochemical parameters of blood in residents of the European North with mandibular fractures and nutrition]. |
| PubMed:Growth and production of cholesterol oxidase by alginate-immobilized cells of Rhodococcus equi No. 23. |
| PubMed:Encapsulation of probiotic bacteria with alginate-starch and evaluation of survival in simulated gastrointestinal conditions and in yoghurt. |
| PubMed:Continuous production of lacticin 3147 and nisin using cells immobilized in calcium alginate. |
| PubMed:Inhibition of Salmonella on poultry skin using protein- and polysaccharide-based films containing a nisin formulation. |
| PubMed:Glucose oxidase release from calcium alginate gel capsules. |
| PubMed:Incorporation of nisin in micro-particles of calcium alginate. |
| PubMed:Reduction of Brochothrix thermosphacta on beef surfaces following immobilization of nisin in calcium alginate gels. |
| PubMed:The use of chitosan to increase the stability of calcium alginate beads with entrapped yeast cells. |
| PubMed:Survival of pseudorabies virus on swabs maintained under standard field sample shipping conditions. |
| PubMed:Propionic acid production by immobilized cells of a propionate-tolerant strain of Propionibacterium acidipropionici. |
| PubMed:[Effect of algisorb on decontamination of milk contaminated with 90Sr]. |
| PubMed:Computer-aided modeling and optimization for capsaicinoid production by immobilized Capsicum frutescens cells. |
| PubMed:Improving survival of culture bacteria in frozen desserts by microentrapment. |
| PubMed:Degradation of acrylamide by immobilized cells of a Pseudomonas sp. and Xanthomonas maltophilia. |
| PubMed:Immobilization of aminoacylase by encapsulation in poly-L-lysine-stabilized calcium alginate beads. |
| PubMed:Production of Concentrated Lactococcus lactis subsp. cremoris Suspensions in Calcium Alginate Beads. |
| PubMed:Effect of viscous indigestible polysaccharides on pancreatic-biliary secretion and digestive organs in rats. |
| PubMed:Solubilization of fish proteins using immobilized microbial cells. |
| PubMed:Operation of fluidized-bed bioreactor containing immobilized yeast cells and the diacetyl levels of green beer. |
| PubMed:An evaluation of the interactions between freshwater pulmonate snail hosts of human schistosomes and macrophytes. |
| PubMed:Hyperexpression of Escherichia coli Xylose Isomerase. |
| PubMed:Reduction of 85Sr, 137Cs, 131I and 141Ce retention in rats by simultaneous oral administration of calcium alginate, ferrihexacyanoferrate(II), KI and Zn-DTPA. |
| PubMed:Optimization of organic solvent in multiphase biocatalysis. |
| PubMed:A new technique for the production of immobilized biocatalyst in large quantities. |
| PubMed:Swab and excised tissue sampling for total and Enterobacteriaceae counts of fresh and surface-frozen broiler skin. |
| PubMed:Comparison of materials used for cleaning equipment in retail food premises, and of two methods for the enumeration of bacteria on cleaned equipment and work surfaces. |
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Stabiliser, emulsifier, thickener, formulation aid
Calcium alginate is an water-insoluble, gelatinous, cream coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. Adding artificial flavours and colours creates a more tasty edible slime. Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in Plant tissue culture.
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