EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

spermine
1,4-diaminobutane, N,N'-bis(3-aminopropyl)-

Supplier Sponsors

CAS Number: 71-44-3Picture of molecule3D/inchi
Other(deleted CASRN):115-04-8
ECHA EINECS - REACH Pre-Reg:200-754-2
FDA UNII: 2FZ7Y3VOQX
Nikkaji Web:J5.246I
Beilstein Number:1750791
MDL:MFCD00008215
XlogP3-AA:-1.10 (est)
Molecular Weight:202.34522000
Formula:C10 H26 N4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 29.00 °C. @ 760.00 mm Hg
Boiling Point: 308.38 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): -0.543 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Spermine 95%
Odor: characteristic
Use: Biogenic polyamine formed from spermidine and occurring in almost all tissues. Essential for both normal and neoplas
Glentham Life Sciences
Spermine
Penta International
SPERMINE
Santa Cruz Biotechnology
For experimental / research use only.
Spermine ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
Spermine ≥97%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD30 650 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Agents and Actions, A Swiss Journal of Pharmacology. Vol. 14, Pg. 228, 1984.

intravenous-mouse LD50 56 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00641

intraperitoneal-mouse LDLo 8 mg/kg
Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.

intraperitoneal-rat LD50 33 mg/kg
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 88, Pg. 433, 1987.

intravenous-rat LD50 65 mg/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 165, Pg. 374, 1967.

Dermal Toxicity:
subcutaneous-mouse LD30 280 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Agents and Actions, A Swiss Journal of Pharmacology. Vol. 14, Pg. 228, 1984.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for spermine usage levels up to:
 not for fragrance use.
 
Recommendation for spermine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):71-44-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1103
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
N,N'-bis(3-aminopropyl)butane-1,4-diamine
Chemidplus:0000071443
RTECS:EJ7175000 for cas# 71-44-3
 
References:
 N,N'-bis(3-aminopropyl)butane-1,4-diamine
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):1103
Pubchem (sid):134972142
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00750
HMDB (The Human Metabolome Database):HMDB01256
FooDB:FDB003225
YMDB (Yeast Metabolome Database):YMDB00231
Export Tariff Code:2921.29.0055
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 apple bud
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 barley seed
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 bean adzuki bean
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 bean banner bean
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 bean butter bean
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 bean fava bean
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 bean field bean
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 bean mung bean
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 bean scarlet runner bean
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 bean winged bean
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 black gram
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 coffee bean
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 corn seed
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 oat leaf
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 pea black-eyed pea
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 pea leaf
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 pea white pea
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 peanut
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 radish leaf
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 soybean seed
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Synonyms:
1,4-bis(aminopropyl) butanediamine
N1,N4-bis(3-aminopropyl)-1,4-butanediamine
N,N'-bis(3-aminopropyl)-1,4-tetramethylenediamine
N,N'-bis(3-aminopropyl)butane-1,4-diamine
1,4-bis(aminopropyl)butanediamine
N,N'-bis(3-aminopropyl)tetramethylenediamine
1,4-butanediamine, N,N'-bis(3-aminopropyl)-
1,4-butanediamine, N1,N4-bis(3-aminopropyl)-
1,4-diaminobutane, N,N'-bis(3-aminopropyl)-
 gerontine
 musculamine
 neuridine
1,5,10,14-tetraazatetradecane
 

Articles:

PubMed:Changes in the microbial communities of air-packaged and vacuum-packaged common carp (Cyprinus carpio) stored at 4 °C.
PubMed:Changes in the Content of Biogenic Amines and Fatty Acids in High Pressure-Processed Carp Flesh (Cyprinus carpio).
PubMed:Impact of Cell-free Supernatant of Lactic Acid Bacteria on Putrescine and Other Polyamine Formation by Foodborne Pathogens in Ornithine Decarboxylase Broth.
PubMed:Polyamines in conventional and organic vegetables exposed to exogenous ethylene.
PubMed:The genus geobacillus and their biotechnological potential.
PubMed:Preadipocyte proliferation is elevated by calcium sensing receptor activation.
PubMed:Fast determination of biogenic amines in beverages by a core-shell particle column.
PubMed:Control of Polyamine Biosynthesis by Antizyme Inhibitor 1 Is Important for Transcriptional Regulation of Arginine Vasopressin in the Male Rat Hypothalamus.
PubMed:Bioactive amines in Mozzarella cheese from milk with varying somatic cell counts.
PubMed:Effects of plant polyphenols and α-tocopherol on lipid oxidation, microbiological characteristics, and biogenic amines formation in dry-cured bacons.
PubMed:Biogenic amines in Zamorano cheese: factors involved in their accumulation.
PubMed:Functional properties of Claramine: a novel PTP1B inhibitor and insulin-mimetic compound.
PubMed:A novel enzyme with spermine oxidase properties in bovine liver mitochondria: identification and kinetic characterization.
PubMed:Nucleus accumbens AMPA receptor involvement in cocaine-conditioned place preference under different dietary conditions in rats.
PubMed:Brewing effect on levels of biogenic amines in different coffee samples as determined by LC-UV.
PubMed:Micro-scale strategy to detect spermine and spermidine by MALDI-TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC-MS/MS after treatment with spermine and spermidine.
PubMed:Changes in the content of free and conjugated polyamines during Lettuce (Lactuca sativa) growth.
PubMed:Over-expression of mouse ornithine decarboxylase gene under the control of fruit-specific promoter enhances fruit quality in tomato.
PubMed:Biologically active amines in fermented and non-fermented commercial soybean products from the Spanish market.
PubMed:Bioactive amines in sorghum: method optimisation and influence of line, tannin and hydric stress.
PubMed:Polyamine profile in ovine and caprine colostrum and milk.
PubMed:Amine oxidase-based biosensors for spermine and spermidine determination.
PubMed:Nanoparticle strategies for cancer therapeutics: Nucleic acids, polyamines, bovine serum amine oxidase and iron oxide nanoparticles (Review).
PubMed:Simultaneous determination of ten underivatized biogenic amines in meat by liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
PubMed:Microbial succession of grass carp (Ctenopharyngodon idellus) filets during storage at 4°C and its contribution to biogenic amines' formation.
PubMed:The optimisation of traditional fermentation process of white cabbage (in relation to biogenic amines and polyamines content and microbiological profile).
PubMed:Metabolomic strategy for the detection of metabolic effects of spermine supplementation in weaned rats.
PubMed:Effect of autochthonous starter cultures on the biogenic amine content of ewe's milk cheese throughout ripening.
PubMed:The effects of plant growth regulators and L-phenylalanine on phenolic compounds of sweet basil.
PubMed:Solid state fermentation with lactic acid bacteria to improve the nutritional quality of lupin and soya bean.
PubMed:Systematic analysis of the ability of Nitric Oxide donors to dislodge biofilms formed by Salmonella enterica and Escherichia coli O157:H7.
PubMed:Rapid HPLC analysis of amino acids and biogenic amines in wines during fermentation and evaluation of matrix effect.
PubMed:Microbiological quality and biogenic amines in ready-to-eat grilled chicken fillets under vacuum packing, freezing, and high-dose irradiation.
PubMed:Biogenic amines, amino acids and microflora changes in Indian mackerel (Rastrellinger kanagurta) stored at ambient (25-29 °C) and ice temperature (0 °C).
PubMed:Ultra-performance convergence chromatography (UPC²) method for the analysis of biogenic amines in fermented foods.
PubMed:Determination of biogenic amines in traditional Chinese fermented foods by reversed-phase high-performance liquid chromatography (RP-HPLC).
PubMed:Health effects and occurrence of dietary polyamines: a review for the period 2005-mid 2013.
PubMed:Comprehensive analysis of Cirsium spinosissimum Scop., a wild alpine food plant.
PubMed:Biogenic amines in commercially produced Yulu, a Chinese fermented fish sauce.
PubMed:Sensitive quantitation of polyamines in plant foods by ultrasound-assisted benzoylation and dispersive liquid-liquid microextraction with the aid of experimental designs.
PubMed:Expression profiling and ontology analysis of long noncoding RNAs in post-ischemic heart and their implied roles in ischemia/reperfusion injury.
PubMed:Polyamines in response to abiotic stress tolerance through transgenic approaches.
PubMed:Involvement of nucleus accumbens AMPA receptor trafficking in augmentation of D- amphetamine reward in food-restricted rats.
PubMed:Biogenic amines formation in high-pressure processed pike flesh (Esox lucius) during storage.
PubMed:Effect of delayed icing on biogenic amines formation and bacterial contribution of iced common carp (Cyprinus carpio).
PubMed:Simultaneous determination of selected biogenic amines in alcoholic beverage samples by isotachophoretic and chromatographic methods.
PubMed:Nitrogen fertilisation increases biogenic amines and amino acid concentrations in Vitis vinifera var. Riesling musts and wines.
PubMed:Nuclear aggregates of polyamines in a radiation-induced DNA damage model.
PubMed:Resembling breast milk: influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota.
PubMed:The occurrence of N-nitrosamines, residual nitrite and biogenic amines in commercial dry fermented sausages and evaluation of their occasional relation.
PubMed:Effect of MeJA treatment on polyamine, energy status and anthracnose rot of loquat fruit.
PubMed:Polyamine levels in breast milk are associated with mothers' dietary intake and are higher in preterm than full-term human milk and formulas.
PubMed:Influence of microflora composition on safety and colour parameters of "kumpia wieprzowa" during ripening.
PubMed:Metabolic survey of defense responses to a compatible hemibiotroph, Phytophthora parasitica var. nicotianae, in ethylene signaling-impaired tobacco.
PubMed:Quality properties, fatty acids, and biogenic amines profile of fresh tilapia stored in ice.
PubMed:Monitoring of biogenic amines in cheeses manufactured at small-scale farms and in fermented dairy products in the Czech Republic.
PubMed:[Determination of eight biogenic amines in animal-derived foodstuffs by high performance liquid chromatography-tandem mass spectrometry without derivatization].
PubMed:Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.
PubMed:The use of Transwells™ improves the rates of differentiation and growth of cultured 3T3L1 cells.
PubMed:Diversity of (dihydro) hydroxycinnamic acid conjugates in Colombian potato tubers.
PubMed:Melatonin is formed during winemaking at safe levels of biogenic amines.
PubMed:Effects of different freezing treatments on the biogenic amine and quality changes of bighead carp (Aristichthys nobilis) heads during ice storage.
PubMed:A review of the liquid chromatographic methods for the determination of biogenic amines in foods.
PubMed:Effect of high-pressure treatment on biogenic amines formation in vacuum-packed trout flesh (Oncorhynchus mykiss).
PubMed:Occurrence of biogenic amines in Miso, Japanese traditional fermented soybean paste.
PubMed:Food polyamine and cardiovascular disease--an epidemiological study.
PubMed:Polyamine Oxidase and Diamine Oxidase Activities in Human Milk during the First Month of Lactation.
PubMed:A multiresidual method based on ion-exchange chromatography with conductivity detection for the determination of biogenic amines in food and beverages.
PubMed:The nitric oxide donor sodium nitroprusside regulates polyamine and proline metabolism in leaves of Medicago truncatula plants.
PubMed:Levels of biogenic amines in retail market fermented meat products.
PubMed:Biogenic amines in low- and reduced-fat dry fermented sausages formulated with konjac gel.
PubMed:Polyamine conjugates of stigmasterol.
PubMed:Effects of inulin or yeast cell-wall extract on nutrient digestibility, fecal fermentative end-product concentrations, and blood metabolite concentrations in adult dogs fed raw meat-based diets.
PubMed:Focused review: agmatine in fermented foods.
PubMed:The determination and characterisation of 2-naphthyloxycarbonyl chloride derivatised biogenic amines in pet foods.
PubMed:Changes in biogenic amines of silver carp (Hypophthalmichthys molitrix) fillets stored at different temperatures and their relation to total volatile base nitrogen, microbiological and sensory score.
PubMed:Dietary polyamine intake and risk of colorectal adenomatous polyps.
PubMed:Evaluation of biogenic amines content in chilean reserve varietal wines.
PubMed:Biogenic amine profile in unripe Arabica coffee beans processed according to dry and wet methods.
PubMed:Biogenic amines content during extended ageing of dry-cured pork loins inoculated with probiotics.
PubMed:Biogenic amines and ethyl carbamate in primitivo wine: survey of their concentrations in commercial products and relationship with the use of malolactic starter.
PubMed:Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice.
PubMed:Development of stable isotope dilution assays for the simultaneous quantitation of biogenic amines and polyamines in foods by LC-MS/MS.
PubMed:Purification of diamine oxidase and its properties in germinated fava bean (Vicia faba L.).
PubMed:Application of a molecularly imprinted polymer for the extraction of kukoamine a from potato peels.
PubMed:Concentration of biologically active polyamines in rabbit meat, liver and kidney after slaughter and their changes during meat storage and cooking.
PubMed:Safety evaluation in vitro of Enterococcus durans from Tibetan traditional fermented yak milk.
PubMed:Biogenic amines and potential histamine - Forming bacteria in Rihaakuru (a cooked fish paste).
PubMed:Synergistic and antagonistic effect of lactic acid bacteria on tyramine production by food-borne pathogenic bacteria in tyrosine decarboxylase broth.
PubMed:Determination of biogenic amines in infusions of tea (Camellia sinensis) by HPLC after derivatization with 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl).
PubMed:Methyl salicylate-induced arginine catabolism is associated with up-regulation of polyamine and nitric oxide levels and improves chilling tolerance in cherry tomato fruit.
PubMed:Protein-conjugated acrolein as a biochemical marker of brain infarction.
PubMed:Influence of putrescine, cadaverine, spermidine or spermine on the formation of N-nitrosamine in heated cured pork meat.
PubMed:Control of biogenic amines in food--existing and emerging approaches.
PubMed:Low-fat frankfurters formulated with a healthier lipid combination as functional ingredient: microstructure, lipid oxidation, nitrite content, microbiological changes and biogenic amine formation.
PubMed:Biogenic amine contents in selected Egyptian fermented foods as determined by ion-exchange chromatography.
PubMed:Ovarian steroids modulate tumor necrosis factor-α and nitric oxide-regulated prostaglandin secretion by cultured bovine oviductal epithelial cells.
PubMed:Enhancement of gastrointestinal absorption of ovalbumin caused by spermine induces an increase in plasma histamine levels in mice sensitized to ovalbumin.
PubMed:Procedures to evaluate the importance of dietary polyamines.
PubMed:Polyamines: total daily intake in adolescents compared to the intake estimated from the Swedish Nutrition Recommendations Objectified (SNO).
PubMed:Polyamines in foods: development of a food database.
PubMed:Concentration of biologically active polyamines in meat and liver of sheep and lambs after slaughter and their changes in mutton during storage and cooking.
PubMed:Polyamines and abiotic stress tolerance in plants.
PubMed:Organoclays as soil amendments to increase the efficacy and reduce the environmental impact of the herbicide fluometuron in agricultural soils.
PubMed:Production of vasoactive amines during the ripening of Pecorino Carmasciano cheese.
PubMed:MSI-1436 reduces acute food intake without affecting dopamine transporter activity.
PubMed:Assessment of washing with antioxidant on the oxidative stability of fatty fish mince during processing and storage.
PubMed:Content of polyamines in by-products of slaughter pigs.
PubMed:Lactobacillus rhamnosus GG influences polyamine metabolism in HGC-27 gastric cancer cell line: a strategy toward nutritional approach to chemoprevention of gastric cance.
PubMed:Polyamine biosynthetic diversity in plants and algae.
PubMed:Determination of biogenic amines in Korean traditional fermented soybean paste (Doenjang).
PubMed:Differential effects of cold, osmotic stress and abscisic acid on polyamine accumulation in wheat.
PubMed:AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats.
PubMed:The use of selected ion flow tube mass spectrometry to detect and quantify polyamines in headspace gas and oral air.
PubMed:A new ultra-pressure liquid chromatography method for the determination of biogenic amines in cheese.
PubMed:Validation of an ultra high pressure liquid chromatographic method for the determination of biologically active amines in food.
PubMed:Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
PubMed:Effects of dietary polyamines at physiologic doses in early-weaned piglets.
PubMed:A method for benzoyl chloride derivatization of biogenic amines for high performance liquid chromatography.
PubMed:The in vitro nuclear aggregates of polyamines.
PubMed:Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia.
PubMed:Irradiated Chinese Rugao ham: Changes in volatile N-nitrosamine, biogenic amine and residual nitrite during ripening and post-ripening.
PubMed:Reward-potentiating effects of D-1 dopamine receptor agonist and AMPAR GluR1 antagonist in nucleus accumbens shell and their modulation by food restriction.
PubMed:Polyamine metabolism and transforming growth factor-beta signaling are affected in Caco-2 cells by differentially cooked broccoli extracts.
PubMed:Effect of aging on bioactive amines, microbial flora, physico-chemical characteristics, and tenderness of broiler breast meat.
PubMed:Comparative survey of putrescine production from agmatine deamination in different bacteria.
PubMed:Spermine-induced morphogenesis and effect of partial immersion system on the shoot cultures of banana.
PubMed:Nucleotide degradation and biogenic amine formation of wild white grouper (Epinephelus aeneus) stored in ice and at chill temperature (4°C).
PubMed:Formation of biogenic amines and relation to microbial flora and sensory changes in smoked turkey breast fillets stored under various packaging conditions at 4 degrees C.
PubMed:Food safety evaluation of broccoli and radish sprouts.
PubMed:A new hydrophilic interaction liquid chromatography tandem mass spectrometry method for the simultaneous determination of seven biogenic amines in cheese.
PubMed:Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease.
PubMed:Effects of starter cultures and nitrite levels on formation of biogenic amines in sucuk.
PubMed:[Estimation of urinary diacetylspermine in Yusho patients].
PubMed:Selective modification of clay minerals for the adsorption of herbicides widely used in olive groves.
PubMed:Polyamines in tea processing.
PubMed:Development of a polyamine database for assessing dietary intake.
PubMed:Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
PubMed:[Effect of spermine on cell growth and polysaccharide production in suspension cultures of protocorm-like bodies from Dendrobium huoshanense].
PubMed:Determination of biogenic amines in squid and white prawn by high-performance liquid chromatography with postcolumn derivatization.
PubMed:Determination of biogenic amines in alcoholic beverages by ion chromatography with suppressed conductivity detection and integrated pulsed amperometric detection.
PubMed:Effect of drought stress at supraoptimal temperature on polyamine concentrations in transgenic soybean with increased proline levels.
PubMed:Biogenic amine formation and nitrite reactions in meat batter as affected by high-pressure processing and chilled storage.
PubMed:Influence of lupin (Lupinus luteus L. cv. 4492 and Lupinus angustifolius L. var. zapaton) and fenugreek (Trigonella foenum-graecum L.) germination on microbial population and biogenic amines.
PubMed:Characterization of the Enterobacteriaceae isolated from an artisanal Italian ewe's cheese (Pecorino Abruzzese).
PubMed:Improved method for the determination of biogenic amines and polyamines in vegetable products by ion-pair high-performance liquid chromatography.
PubMed:Characterization and a role of Pseudomonas aeruginosa spermidine dehydrogenase in polyamine catabolism.
PubMed:Relation of biogenic amines' formation with microbiological and sensory attributes in Lactobacillus-inoculated vacuum-packed rainbow trout (Oncorhynchus mykiss) fillets.
PubMed:Correlation between microbial flora, sensory changes and biogenic amines formation in fresh chicken meat stored aerobically or under modified atmosphere packaging at 4 degrees C: possible role of biogenic amines as spoilage indicators.
PubMed:Effects of peritoneal aluminum overload on polyamines and nitric oxide contents of testes and epididymis in the mice.
PubMed:Effect of natural and synthetic polyamines on ethanol intake in UChB drinker rats.
PubMed:[Method of determination of biogenic amines in wines by high-performance liquid chromatography with fluorescence detector and ultraviolet detector].
PubMed:Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells.
PubMed:Effect of ME-3451-106, an aqueous extract of Stichaster striatus with inhibitory activity of voluntary alcohol intake, in genetically drinker rats: Isolation and identification of the active fraction.
PubMed:Enhancement of growth and coumarin production in hairy root cultures of witloof chicory (Cichorium intybus L.cv. Lucknow local) under the influence of fungal elicitors.
PubMed:Influence of cultivar and germination on bioactive amines in soybeans (Glycine max L. Merril).
PubMed:Effect of food components and processing parameters on DNA degradation in food.
PubMed:Dihydrocaffeoyl polyamines (kukoamine and allies) in potato (Solanum tuberosum) tubers detected during metabolite profiling.
PubMed:A new polyamine derivative, a structural analog of spermine, with in vivo activity as an inhibitor of ethanol appetite.
PubMed:Propyl paraben induces potassium efflux in Escherichia coli.
PubMed:Involvement of polyamines in evening primrose extract-induced apoptosis in Ehrlich ascites tumor cells.
PubMed:Interrelationships among microbiological, physicochemical, and biochemical properties of Terrincho cheese, with emphasis on biogenic amines.
PubMed:Free and conjugated biogenic amines in green and roasted coffee beans.
PubMed:New solvent systems for thin-layer chromatographic determination of nine biogenic amines in fish and squid.
PubMed:Effects of prostaglandin F(2alpha) and nitric oxide on the secretory function of bovine luteal cells.
PubMed:The effects of lactic acid bacteria inoculants and formic acid on the formation of biogenic amines in grass silages.
PubMed:Evaluation of biogenic amines and microbial counts throughout the ripening of goat cheeses from pasteurized and raw milk.
PubMed:Relation of biogenic amines with microbial and sensory changes of whole and filleted freshwater rainbow trout (Onchorynchus mykiss) stored on ice.
PubMed:Tyramine functions as a toxin in honey bee larvae during Varroa-transmitted infection by Melissococcus pluton.
PubMed:Biogenic amines in restructured beef steaks as affected by added walnuts and cold storage.
PubMed:On-line solid-phase extraction with surfactant accelerated on-column derivatization and micellar liquid chromatographic separation as a tool for the determination of biogenic amines in various food substrates.
PubMed:Polyamine homeostasis in transgenic plants overexpressing ornithine decarboxylase includes ornithine limitation.
PubMed:The effects of using lactic acid bacteria inoculants in maize silage on the formation of biogenic amines.
PubMed:[Herbivore elicitors and plant signaling pathways involved in the production of herbivore-induced plant volatiles].
PubMed:First evidence on induced topological changes in supercoiled DNA by an aluminium D-aspartate complex.
PubMed:Determination of biogenic amines as their benzoyl derivatives after cloud point extraction with micellar liquid chromatographic separation.
PubMed:Effects of exogenous polyamines on growth, toxicity, and toxin profile of dinoflagellate Alexandrium minutum.
PubMed:The influence of the brewing process on the formation of biogenic amines in beers.
PubMed:Abrogation of upstream open reading frame-mediated translational control of a plant S-adenosylmethionine decarboxylase results in polyamine disruption and growth perturbations.
PubMed:High-performance liquid chromatographic determination of biogenic amines in poultry carcasses.
PubMed:Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations.
PubMed:Characterization of selected Spanish table wine samples according to their biogenic amine content from liquid chromatographic determination.
PubMed:Appetite suppression and weight reduction by a centrally active aminosterol.
PubMed:Biogenic amine accumulation in ripened sausages affected by the addition of sodium sulphite.
PubMed:Quality changes and shelf life of imported vacuum-packaged beef chuck during storage at 0°C.
PubMed:Ornithine decarboxylase and thymidine kinase activities and polyamine levels from selected organs of adult miniature swine receiving three concentrations of dietary menhaden oil.
PubMed:Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
PubMed:Antifungal activity of three spermidine conjugates.
PubMed:Dietary spermidine and spermine participate in the maturation of galactosyltransferase activity and glycoprotein galactosylation in rat small intestine.
PubMed:A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties.
PubMed:Influence of heavy metals on the accumulation of trimethylglycine, putrescine and spermine in food plants.
PubMed:Effect of the interaction between a low tyramine-producing Lactobacillus and proteolytic staphylococci on biogenic amine production during ripening and storage of dry sausages.
PubMed:Chemical, microbiological, and AromaScan evaluation of mahi-mahi fillets under various storage conditions.
PubMed:Biogenic amines in vacuum-packaged and carbon dioxide-controlled atmosphere-packaged fresh pork stored at -1.50 degrees C.
PubMed:Polyamines in human and animal milk.
PubMed:Changes in biogenic amine and polyamine contents in slightly fermented sausages manufactured with and without sugar.
PubMed:Apoptosis induced by 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells is associated with modulation of polyamine metabolism and caspase-3 activation.
PubMed:Analysis of amines in plant materials.
PubMed:Biogenic amines and polyamines in milks and cheeses by ion-pair high performance liquid chromatography.
PubMed:Mixed starter cultures to control biogenic amine production in dry fermented sausages.
PubMed:Putrescine and Silver Nitrate Influences Shoot Multiplication, In Vitro Flowering and Endogenous Titers of Polyamines in Cichorium intybus L. cv. Lucknow Local.
PubMed:Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity.
PubMed:Liquid chromatographic determination of biogenic amines in fermented foods after derivatization with 3,5-dinitrobenzoyl chloride.
PubMed:Are milk polyamines preventive agents against food allergy?
PubMed:High-performance liquid chromatographic method for determination of biogenic amines in feedstuffs, complete feeds, and animal tissues.
PubMed:Effect of proteolytic starter cultures of Staphylococcus spp. on biogenic amine formation during the ripening of dry fermented sausages.
PubMed:Changes in biogenic amines in mature and germinating legume seeds and their behavior during cooking.
PubMed:Histamine and biogenic amine production by Morganella morganii isolated from temperature-abused albacore.
PubMed:Reduction of biogenic amine formation using a negative amino acid-decarboxylase starter culture for fermentation of Fuet sausages.
PubMed:Putrescine Influences Growth and Production of Coumarins in Hairy Root Cultures of Witloof Chicory (Cichorium intybus L. cv. Lucknow Local).
PubMed:Nucleotide and polyamine levels in colostrum and mature milk in relation to maternal atopy and atopic development in the children.
PubMed:Influence of spermine on intestinal maturation of the glycoprotein glycosylation process in neonatal rats.
PubMed:Ability of amino acids, dipeptides, polyamines, and sulfhydryls to quench hexanal, a saturated aldehydic lipid oxidation product.
PubMed:Influence of Polyamines on Growth of Hairy Root Cultures of Witloof Chicory (Cichorium intybus L. cv. Lucknow Local) and Formation of Coumarins.
PubMed:Changes in polyamines and ethylene during the development and ripening of eggplant fruits (Solanum melongena).
PubMed:Ability of carnosine and other skeletal muscle components to quench unsaturated aldehydic lipid oxidation products.
PubMed:Histamine and cadaverine production by bacteria isolated from fresh and frozen albacore (Thunnus alalunga).
PubMed:Inhibition of liver glutathione S-transferase placental form-positive foci development in the rat hepatocarcinogenesis by Porphyra tenera (Asakusa-nori).
PubMed:[Importance of the polyamines: review of the literature].
PubMed:Biogenic amines and sensory changes associated with the microbial flora of Mediterranean gilt-head sea bream (Sparus aurata) stored aerobically at 0, 8, and 15 degrees C.
PubMed:Determination of biogenic amines by capillary electrophoresis.
PubMed:Bilirubin binding activity of cytokeratin 18 isolated from the porcine liver.
PubMed:Phencyclidine-like discriminative stimulus effects of polyamine modulators of N-methyl-D-aspartate receptor activity in rats.
PubMed:Changes in biogenic amines and microbiological analysis in albacore (Thunnus alalunga) muscle during frozen storage.
PubMed:Effect of lectins on uptake of polyamines.
PubMed:Determination of biogenic amines in cheese.
PubMed:Overexpression of arginine decarboxylase in transgenic plants.
PubMed:Involvement of polyamines in the protection of taurine against the cytotoxicity of hydrazine or carbon tetrachloride in isolated rat hepatocytes.
PubMed:Acute and subacute toxicity of tyramine, spermidine, spermine, putrescine and cadaverine in rats.
PubMed:Subacute toxicity of a mixture of nine chemicals in rats: detecting interactive effects with a fractionated two-level factorial design.
PubMed:Studies on the inactivation of superoxide dismutase activity by nitric oxide from rat peritoneal macrophages.
PubMed:Fasting and postprandial polyamine concentrations in the human digestive lumen.
PubMed:Enteral supplementation with ornithine alpha ketoglutarate improves the early adaptive response to resection.
PubMed:Growth inhibition of subcutaneously transplanted hepatomas by alterations of the dietary arginine-methionine balance.
PubMed:Assay of biogenic amines involved in fish decomposition.
PubMed:Polyamine profiles in human milk, infant artificial formulas, and semi-elemental diets.
PubMed:Liquid chromatographic method for determination of biogenic amines in fish and fish products.
PubMed:Biogenic amines and microbial quality of sprouts.
PubMed:Vitamin A status and metabolism of cutaneous polyamines in the hairless mouse after UV irradiation: action of beta-carotene and astaxanthin.
PubMed:Stimulating effect of excess iron feeding on spontaneous lung tumor promotion in mice.
PubMed:Effect of sucrose monostearate, an emulsifier, on polyamine metabolism and phosphatidylinositol turnover in Ehrlich ascites tumor cells.
PubMed:Induction of postprandial intestinal motility and release of cholecystokinin by polyamines in rats.
PubMed:Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12.
PubMed:Determination of biogenic amines in leafy vegetables by amino acid analyser.
PubMed:Liquid chromatographic determination of biogenic amines in dry sausages.
PubMed:Pathological changes in platelet histamine oxidases in atopic eczema.
PubMed:Biogenic amines in silage. 2. The dynamics of the formation of biogenic amines in silage.
PubMed:Biogenic amines in silage. 3. The occurrence of six biogenic amines in farm-scale grass and maize silages.
PubMed:Polyamines in human and rat milk and in infant formulas.
PubMed:Polyamine concentration in rat milk and food, human milk, and infant formulas.
PubMed:Improvement of extraction procedure for biogenic amines in foods and their high-performance liquid chromatographic determination.
PubMed:[Refractory diarrhea in infants: experimental basis of current therapeutic perspectives].
PubMed:Change in endocrine pancreatic function in short-term diet restriction.
PubMed:Is there a role for amines other than histamines in the aetiology of scombrotoxicosis?
PubMed:[Biogenic amine contents in fish and fish preserves].
PubMed:Polyamines and long-term disuse of rat parotid glands.
PubMed:Bioamines and proteins in the saliva and salivary glands of Palaearctic blackflies (Diptera: Simuliidae).
PubMed:Effect of fasting and feeding on polyamines and related enzymes along the villus: crypt axis.
PubMed:Effect of dietary zinc deficiency and the associated drop in voluntary food intake on rat erythrocyte membrane polyamines.
PubMed:[Determination of biogenic amines by RP-HPLC for monitoring the microbial spoilage of poultry].
PubMed:Effects of food restriction and hyperoxia on rat survival and lung polyamine metabolism.
PubMed:Amines in fresh beef of normal pH and the role of bacteria in changes in concentration observed during storage in vacuum packs at chill temperatures.
PubMed:Red blood cell polyamine levels and host toxicity during continuous alpha-difluoromethylornithine infusion.
PubMed:Skeletal growth in experimental uremia.
PubMed:Effect of starvation and refeeding on polyamine concentrations and ornithine decarboxylase antizyme in mammary gland of lactating rats.
PubMed:Determination of mono-, di- and polyamines in foods using a single-column amino acid auto-analyzer.
PubMed:Mutagenicity of pyrolysates from guanidine, ureide, secondary amines and polyamines found by the Salmonella/mammalian-microsome test.
PubMed:Effect of diaminobutene and diaminopropane on diet-stimulated polyamine synthesis and cell proliferation in rat liver.
PubMed:Correlation between circadian rhythms of polyamine synthesis and cell proliferation in rat liver.
PubMed:Determination of amines in fresh and processed pork.
PubMed:Identification of gamma-butenyl-(beta-propenyl) nitrosamine, the principal volatile nitrosamine formed in the nitrosation of spermidine of spermine.
PubMed:Effects of processing on the amine content of pork bellies.
PubMed:[Relationships between polyamines and nucleic acids. I. Influence of food deprivation, phenobarbital and perfluorobutyric acid on the nucleic acid, spermine and spermidine content of mouse liver].
PubMed:[Effect of food deprivation, phenobarbital and perfluorobutyric acid on the content of nucleic acids, spermidine and spermine in the mouse liver].
 
Notes:
a biogenic polyamine formed from spermidine. it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. it is found as a polycation at all ph values. spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure. Occurs as phosphate in ox pancreas, yeast and meat products Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine, it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at physiological pH. Spermine is associated with nucleic acids and is thought to stabilize helical structure, in particular, in viruses. (Wikipedia)
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