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CAS Number: 18658-42-9

SMILES : CC(C)CC1C(=O)NC=Cc2ccc(cc2)OC(C(C(=O)N1)NC(=O)C3CCCN3C)C(C)C

CHEM :

MOL FOR: C26 H38 N4 O4

MOL WT : 470.62

------------------------------ EPI SUMMARY (v4.11) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 1.67

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 745.81 (Adapted Stein & Brown method)

Melting Pt (deg C): 327.42 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 3.71E-018 (Modified Grain method)

VP (Pa, 25 deg C) : 4.95E-016 (Modified Grain method)

Subcooled liquid VP: 9.75E-015 mm Hg (25 deg C, Mod-Grain method)

: 1.3E-012 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 41.23

log Kow used: 1.67 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 20130 mg/L

ECOSAR Class Program (ECOSAR v1.11):

Class(es) found:

Aliphatic Amines

Amides

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 1.97E-019 atm-m3/mole (2.00E-014 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 5.572E-020 atm-m3/mole (5.646E-015 Pa-m3/mole)

VP: 3.71E-018 mm Hg (source: MPBPVP)

WS: 41.2 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 1.67 (KowWin est)

Log Kaw used: -17.094 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 18.764

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 1.0806

Biowin2 (Non-Linear Model) : 0.9882

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 1.6836 (recalcitrant)

Biowin4 (Primary Survey Model) : 3.5742 (days-weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.0933

Biowin6 (MITI Non-Linear Model): 0.0010

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -3.1990

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 1.3E-012 Pa (9.75E-015 mm Hg)

Log Koa (Koawin est ): 18.764

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 2.31E+006

Octanol/air (Koa) model: 1.43E+006

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 1

Mackay model : 1

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 240.4483 E-12 cm3/molecule-sec

Half-Life = 0.044 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 0.534 Hrs

Ozone Reaction:

OVERALL Ozone Rate Constant = 2.100000 E-17 cm3/molecule-sec

Half-Life = 0.546 Days (at 7E11 mol/cm3)

Half-Life = 13.097 Hrs

Fraction sorbed to airborne particulates (phi):

1 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 1.019E+005 L/kg (MCI method)

Log Koc: 5.008 (MCI method)

Koc : 58.4 L/kg (Kow method)

Log Koc: 1.766 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 0.770 (BCF = 5.886 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -2.3287 days (HL = 0.004691 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.228 (BCF = 1.69)

Log BAF Arnot-Gobas method (upper trophic) = 0.228 (BAF = 1.69)

log Kow used: 1.67 (estimated)

Volatilization from Water:

Henry LC: 1.97E-019 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 6.447E+015 hours (2.686E+014 days)

Half-Life from Model Lake : 7.033E+016 hours (2.931E+015 days)

Removal In Wastewater Treatment:

Total removal: 2.03 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.94 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 6.14e-005 0.987 1000

Water 2.17 4.32e+003 1000

Soil 73.3 8.64e+003 1000

Sediment 24.6 3.89e+004 0

Persistence Time: 1.07e+004 hr

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