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CAS Number: 239110-15-7

SMILES : c1cc(c(c(c1)CL)C(=O)NCc2c(cc(cn2)C(F)(F)F)CL)CL

CHEM :

MOL FOR: C14 H8 CL3 F3 N2 O1

MOL WT : 383.59

------------------------------ EPI SUMMARY (v4.10) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 4.62

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 455.03 (Adapted Stein & Brown method)

Melting Pt (deg C): 191.59 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 6.59E-009 (Modified Grain method)

VP (Pa, 25 deg C) : 8.79E-007 (Modified Grain method)

Subcooled liquid VP: 3.69E-007 mm Hg (25 deg C, Mod-Grain method)

: 4.92E-005 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 0.4386

log Kow used: 4.62 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 4.5142 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Amides

Halo Benzamides

Halopyrdines

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 1.82E-012 atm-m3/mole (1.84E-007 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 7.584E-009 atm-m3/mole (7.684E-004 Pa-m3/mole)

VP: 6.59E-009 mm Hg (source: MPBPVP)

WS: 0.439 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 4.62 (KowWin est)

Log Kaw used: -10.128 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 14.748

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : -0.4472

Biowin2 (Non-Linear Model) : 0.0000

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 0.9504 (recalcitrant)

Biowin4 (Primary Survey Model) : 2.7106 (weeks-months)

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.2798

Biowin6 (MITI Non-Linear Model): 0.0000

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -0.7820

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 4.92E-005 Pa (3.69E-007 mm Hg)

Log Koa (Koawin est ): 14.748

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 0.061

Octanol/air (Koa) model: 137

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 0.688

Mackay model : 0.83

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 4.7570 E-12 cm3/molecule-sec

Half-Life = 2.248 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 26.982 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Fraction sorbed to airborne particulates (phi):

0.759 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 2.481E+004 L/kg (MCI method)

Log Koc: 4.395 (MCI method)

Koc : 3550 L/kg (Kow method)

Log Koc: 3.550 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 2.715 (BCF = 519 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -0.2575 days (HL = 0.5527 days)

Log BCF Arnot-Gobas method (upper trophic) = 2.345 (BCF = 221.5)

Log BAF Arnot-Gobas method (upper trophic) = 2.346 (BAF = 221.7)

log Kow used: 4.62 (estimated)

Volatilization from Water:

Henry LC: 1.82E-012 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 6.301E+008 hours (2.625E+007 days)

Half-Life from Model Lake : 6.873E+009 hours (2.864E+008 days)

Removal In Wastewater Treatment:

Total removal: 62.16 percent

Total biodegradation: 0.57 percent

Total sludge adsorption: 61.60 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 1.12e-005 54 1000

Water 3.24 4.32e+003 1000

Soil 87.2 8.64e+003 1000

Sediment 9.6 3.89e+004 0

Persistence Time: 9e+003 hr

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