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CAS Number: 180409-60-3

SMILES : FC(F)(F)c3ccc(F)c(F)c3C(=NC(=O)Cc1ccccc1)NOCC2CC2

CHEM :

MOL FOR: C20 H17 F5 N2 O2

MOL WT : 412.36

------------------------------ EPI SUMMARY (v4.10) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 5.60

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 441.08 (Adapted Stein & Brown method)

Melting Pt (deg C): 184.07 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 1.79E-008 (Modified Grain method)

VP (Pa, 25 deg C) : 2.38E-006 (Modified Grain method)

Subcooled liquid VP: 8.18E-007 mm Hg (25 deg C, Mod-Grain method)

: 0.000109 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 0.04249

log Kow used: 5.60 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 0.2123 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Amides

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 3.76E-011 atm-m3/mole (3.81E-006 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 2.286E-007 atm-m3/mole (2.316E-002 Pa-m3/mole)

VP: 1.79E-008 mm Hg (source: MPBPVP)

WS: 0.0425 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 5.60 (KowWin est)

Log Kaw used: -8.813 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 14.413

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : -1.4064

Biowin2 (Non-Linear Model) : 0.0000

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 0.9082 (recalcitrant)

Biowin4 (Primary Survey Model) : 2.9417 (weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.3246

Biowin6 (MITI Non-Linear Model): 0.0000

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): 0.0899

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 0.000109 Pa (8.18E-007 mm Hg)

Log Koa (Koawin est ): 14.413

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 0.0275

Octanol/air (Koa) model: 63.5

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 0.498

Mackay model : 0.688

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 6.2462 E-12 cm3/molecule-sec

Half-Life = 1.712 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 20.549 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Fraction sorbed to airborne particulates (phi):

0.593 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 3.602E+007 L/kg (MCI method)

Log Koc: 7.557 (MCI method)

Koc : 1.002E+004 L/kg (Kow method)

Log Koc: 4.001 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 3.361 (BCF = 2295 L/kg wet-wt)

Log Biotransformation Half-life (HL) = 0.7941 days (HL = 6.225 days)

Log BCF Arnot-Gobas method (upper trophic) = 3.332 (BCF = 2146)

Log BAF Arnot-Gobas method (upper trophic) = 3.553 (BAF = 3573)

log Kow used: 5.60 (estimated)

Volatilization from Water:

Henry LC: 3.76E-011 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 3.162E+007 hours (1.318E+006 days)

Half-Life from Model Lake : 3.449E+008 hours (1.437E+007 days)

Removal In Wastewater Treatment:

Total removal: 89.42 percent

Total biodegradation: 0.75 percent

Total sludge adsorption: 88.67 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 7.95e-005 41.1 1000

Water 0.557 4.32e+003 1000

Soil 52.2 8.64e+003 1000

Sediment 47.2 3.89e+004 0

Persistence Time: 1.51e+004 hr

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