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CAS Number: 1180-71-8

SMILES : O1C(=O)CC2OC(C)(C)C3CC(=O)C4(C)C5(O6)C6C(=O)OC(c7cocc7)C5(C)CCC4C23C1

CHEM : Limonin

MOL FOR: C26 H30 O8

MOL WT : 470.52

------------------------------ EPI SUMMARY (v4.10) --------------------------

Henry LC (atm-m3/mole) : ------

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Water Solubility (mg/L): ------

Physical Property Inputs:

Vapor Pressure (mm Hg) : ------

Melting Point (deg C) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 0.72

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 593.68 (Adapted Stein & Brown method)

Melting Pt (deg C): 256.36 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 9.74E-014 (Modified Grain method)

VP (Pa, 25 deg C) : 1.3E-011 (Modified Grain method)

MP (exp database): 298 deg C

Subcooled liquid VP: 1.08E-010 mm Hg (25 deg C, Mod-Grain method)

: 1.44E-008 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 270.2

log Kow used: 0.72 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 395.18 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Epoxides, mono

Esters

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 2.55E-016 atm-m3/mole (2.59E-011 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 2.232E-016 atm-m3/mole (2.261E-011 Pa-m3/mole)

VP: 9.74E-014 mm Hg (source: MPBPVP)

WS: 270 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 0.72 (KowWin est)

Log Kaw used: -13.982 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 14.702

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : -0.7356

Biowin2 (Non-Linear Model) : 0.0000

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 1.3394 (recalcitrant)

Biowin4 (Primary Survey Model) : 2.8179 (weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : 0.6235

Biowin6 (MITI Non-Linear Model): 0.1010

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -2.4115

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 1.44E-008 Pa (1.08E-010 mm Hg)

Log Koa (Koawin est ): 14.702

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 208

Octanol/air (Koa) model: 124

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 1

Mackay model : 1

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 151.4420 E-12 cm3/molecule-sec

Half-Life = 0.071 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 0.848 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Reaction With Nitrate Radicals May Be Important!

Fraction sorbed to airborne particulates (phi):

1 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 3059 L/kg (MCI method)

Log Koc: 3.486 (MCI method)

Koc : 16.09 L/kg (Kow method)

Log Koc: 1.207 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Total Ka (acid-catalyzed) at 25 deg C : 1.843E-006 L/mol-sec

Ka Half-Life at pH 7: 1.191E+005 years

(Total Ka applies to epoxide(s) only)

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 0.500 (BCF = 3.162 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -2.1140 days (HL = 0.007691 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.008 (BCF = 1.019)

Log BAF Arnot-Gobas method (upper trophic) = 0.008 (BAF = 1.019)

log Kow used: 0.72 (estimated)

Volatilization from Water:

Henry LC: 2.55E-016 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 4.98E+012 hours (2.075E+011 days)

Half-Life from Model Lake : 5.433E+013 hours (2.264E+012 days)

Removal In Wastewater Treatment:

Total removal: 1.87 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.78 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 2.07e-005 1.7 1000

Water 4.19 4.32e+003 1000

Soil 94.5 8.64e+003 1000

Sediment 1.28 3.89e+004 0

Persistence Time: 8e+003 hr

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