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CAS Number: 17090-79-8

SMILES : O5C2(CC(O)C(C)C5C(C)C(OC)C(C)C(=O)O)OC(C)(C1OC(CC)(C3OC(C4OC(O)(CO)C(

C)CC4C)CC3C)CC1)CC2

CHEM : MONENSIN

MOL FOR: C36 H62 O11

MOL WT : 670.89

------------------------------ EPI SUMMARY (v4.11) --------------------------

Henry LC (atm-m3/mole) : ------

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Water Solubility (mg/L): ------

Physical Property Inputs:

Vapor Pressure (mm Hg) : ------

Melting Point (deg C) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 5.43

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 739.92 (Adapted Stein & Brown method)

Melting Pt (deg C): 324.67 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 5.17E-023 (Modified Grain method)

VP (Pa, 25 deg C) : 6.89E-021 (Modified Grain method)

Subcooled liquid VP: 1.25E-019 mm Hg (25 deg C, Mod-Grain method)

: 1.67E-017 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 0.00312

log Kow used: 5.43 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 356.69 mg/L

ECOSAR Class Program (ECOSAR v1.11):

Class(es) found:

Neutral Organics-acid

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 2.02E-024 atm-m3/mole (2.05E-019 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 1.463E-020 atm-m3/mole (1.482E-015 Pa-m3/mole)

VP: 5.17E-023 mm Hg (source: MPBPVP)

WS: 0.00312 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 5.43 (KowWin est)

Log Kaw used: -22.083 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 27.513

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : -2.0016

Biowin2 (Non-Linear Model) : 0.0000

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 1.5006 (recalcitrant)

Biowin4 (Primary Survey Model) : 2.8521 (weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.2880

Biowin6 (MITI Non-Linear Model): 0.0000

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -3.1994

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 1.67E-017 Pa (1.25E-019 mm Hg)

Log Koa (Koawin est ): 27.513

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 1.8E+011

Octanol/air (Koa) model: 8E+014

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 1

Mackay model : 1

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 194.5666 E-12 cm3/molecule-sec

Half-Life = 0.055 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 0.660 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Fraction sorbed to airborne particulates (phi):

1 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 365.8 L/kg (MCI method)

Log Koc: 2.563 (MCI method)

Koc : 62.05 L/kg (Kow method)

Log Koc: 1.793 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 1.000 (BCF = 10 L/kg wet-wt)

Log Biotransformation Half-life (HL) = 0.5573 days (HL = 3.608 days)

Log BCF Arnot-Gobas method (upper trophic) = 3.123 (BCF = 1326)

Log BAF Arnot-Gobas method (upper trophic) = 3.190 (BAF = 1551)

log Kow used: 5.43 (estimated)

Volatilization from Water:

Henry LC: 2.02E-024 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 7.507E+020 hours (3.128E+019 days)

Half-Life from Model Lake : 8.19E+021 hours (3.412E+020 days)

Removal In Wastewater Treatment:

Total removal: 87.33 percent

Total biodegradation: 0.74 percent

Total sludge adsorption: 86.59 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 8.19e-005 1.32 1000

Water 7.2 4.32e+003 1000

Soil 92.6 8.64e+003 1000

Sediment 0.177 3.89e+004 0

Persistence Time: 6.32e+003 hr

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