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CAS Number: 529-17-9

SMILES : C(CC1C2)C(N1C)CC2

CHEM : Tropane

MOL FOR: C8 H15 N1

MOL WT : 125.22

------------------------------ EPI SUMMARY (v4.10) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 1.78

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 157.96 (Adapted Stein & Brown method)

Melting Pt (deg C): -6.84 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 1.89 (Mean VP of Antoine & Grain methods)

VP (Pa, 25 deg C) : 252 (Mean VP of Antoine & Grain methods)

BP (exp database): 166 deg C

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 2.95e+004

log Kow used: 1.78 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 18998 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Aliphatic Amines

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 2.93E-005 atm-m3/mole (2.97E+000 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 1.056E-005 atm-m3/mole (1.070E+000 Pa-m3/mole)

VP: 1.89 mm Hg (source: MPBPVP)

WS: 2.95E+004 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 1.78 (KowWin est)

Log Kaw used: -2.922 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 4.702

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 0.4827

Biowin2 (Non-Linear Model) : 0.2705

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 2.6677 (weeks-months)

Biowin4 (Primary Survey Model) : 3.3791 (days-weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : 0.3787

Biowin6 (MITI Non-Linear Model): 0.2718

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -0.8395

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 229 Pa (1.72 mm Hg)

Log Koa (Koawin est ): 4.702

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 1.31E-008

Octanol/air (Koa) model: 1.24E-008

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 4.72E-007

Mackay model : 1.05E-006

Octanol/air (Koa) model: 9.89E-007

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 48.2512 E-12 cm3/molecule-sec

Half-Life = 0.222 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 2.660 Hrs

Ozone Reaction:

No Ozone Reaction Estimation

Fraction sorbed to airborne particulates (phi):

7.6E-007 (Junge-Pankow, Mackay avg)

9.89E-007 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 175.1 L/kg (MCI method)

Log Koc: 2.243 (MCI method)

Koc : 69.87 L/kg (Kow method)

Log Koc: 1.844 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 0.842 (BCF = 6.943 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -0.6947 days (HL = 0.202 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.797 (BCF = 6.273)

Log BAF Arnot-Gobas method (upper trophic) = 0.797 (BAF = 6.273)

log Kow used: 1.78 (estimated)

Volatilization from Water:

Henry LC: 2.93E-005 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 23.5 hours

Half-Life from Model Lake : 350.2 hours (14.59 days)

Removal In Wastewater Treatment:

Total removal: 3.64 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.97 percent

Total to Air: 1.58 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 0.328 5.32 1000

Water 20.7 900 1000

Soil 78.8 1.8e+003 1000

Sediment 0.217 8.1e+003 0

Persistence Time: 886 hr

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