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CAS Number: 482-89-3

SMILES : O=C(c(c(N1)ccc2)c2)C1=C(Nc(c3ccc4)c4)C3(=O)

CHEM : 3H-Indol-3-one, 2-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro-

MOL FOR: C16 H10 N2 O2

MOL WT : 262.27

------------------------------ EPI SUMMARY (v4.10) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 3.11

Log Kow (Exper. database match) = 3.72

Exper. Ref: POMONA (1987)

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 453.36 (Adapted Stein & Brown method)

Melting Pt (deg C): 190.81 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 2.35E-011 (Modified Grain method)

VP (Pa, 25 deg C) : 3.13E-009 (Modified Grain method)

MP (exp database): 390 dec deg C

Subcooled liquid VP: 4.06E-007 mm Hg (25 deg C, Mod-Grain method)

: 5.41E-005 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 13.44

log Kow used: 3.72 (expkow database)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 109.31 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Vinyl/Allyl Ketones

Vinyl/Allyl Amines

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 5.01E-014 atm-m3/mole (5.08E-009 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 6.034E-013 atm-m3/mole (6.114E-008 Pa-m3/mole)

VP: 2.35E-011 mm Hg (source: MPBPVP)

WS: 13.4 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 3.72 (exp database)

Log Kaw used: -11.689 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 15.409

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 0.1688

Biowin2 (Non-Linear Model) : 0.0043

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 2.3047 (weeks-months)

Biowin4 (Primary Survey Model) : 3.2081 (weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.0823

Biowin6 (MITI Non-Linear Model): 0.0076

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -1.2668

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 5.41E-005 Pa (4.06E-007 mm Hg)

Log Koa (Koawin est ): 15.409

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 0.0554

Octanol/air (Koa) model: 630

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 0.667

Mackay model : 0.816

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 82.6242 E-12 cm3/molecule-sec

Half-Life = 0.129 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 1.553 Hrs

Ozone Reaction:

OVERALL Ozone Rate Constant = 0.175000 E-17 cm3/molecule-sec

Half-Life = 6.549 Days (at 7E11 mol/cm3)

Fraction sorbed to airborne particulates (phi):

0.741 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 90.37 L/kg (MCI method)

Log Koc: 1.956 (MCI method)

Koc : 1937 L/kg (Kow method)

Log Koc: 3.287 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 1.536 (BCF = 34.38 L/kg wet-wt)

Log Biotransformation Half-life (HL) = 0.2663 days (HL = 1.846 days)

Log BCF Arnot-Gobas method (upper trophic) = 2.509 (BCF = 322.9)

Log BAF Arnot-Gobas method (upper trophic) = 2.510 (BAF = 323.2)

log Kow used: 3.72 (expkow database)

Volatilization from Water:

Henry LC: 5.01E-014 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 1.893E+010 hours (7.886E+008 days)

Half-Life from Model Lake : 2.065E+011 hours (8.603E+009 days)

Removal In Wastewater Treatment:

Total removal: 19.08 percent

Total biodegradation: 0.23 percent

Total sludge adsorption: 18.85 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 0.000378 3.05 1000

Water 17.8 900 1000

Soil 82.1 1.8e+003 1000

Sediment 0.111 8.1e+003 0

Persistence Time: 1.58e+003 hr

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