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CAS Number: 7220-81-7

SMILES : O=C1C2=C(c5c(c4c(cc5OC)OC3C4CCO3)O1)CCC2(=O)

CHEM : AFLATOXIN B2

MOL FOR: C17 H14 O6

MOL WT : 314.30

------------------------------ EPI SUMMARY (v4.10) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.68 estimate) = 1.45

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 472.50 (Adapted Stein & Brown method)

Melting Pt (deg C): 199.75 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 1.65E-010 (Modified Grain method)

VP (Pa, 25 deg C) : 2.21E-008 (Modified Grain method)

MP (exp database): 287.5 deg C

Subcooled liquid VP: 1.35E-007 mm Hg (25 deg C, Mod-Grain method)

: 1.8E-005 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.42):

Water Solubility at 25 deg C (mg/L): 585.4

log Kow used: 1.45 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 7.7826 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Acrylates

Vinyl/Allyl Ketones

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 2.99E-015 atm-m3/mole (3.03E-010 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 1.166E-013 atm-m3/mole (1.181E-008 Pa-m3/mole)

VP: 1.65E-010 mm Hg (source: MPBPVP)

WS: 585 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 1.45 (KowWin est)

Log Kaw used: -12.913 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 14.363

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 0.7501

Biowin2 (Non-Linear Model) : 0.9785

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 2.4226 (weeks-months)

Biowin4 (Primary Survey Model) : 3.6770 (days-weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : 0.7207

Biowin6 (MITI Non-Linear Model): 0.6198

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): 0.0179

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 1.8E-005 Pa (1.35E-007 mm Hg)

Log Koa (Koawin est ): 14.363

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 0.167

Octanol/air (Koa) model: 56.6

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 0.858

Mackay model : 0.93

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 250.2001 E-12 cm3/molecule-sec

Half-Life = 0.043 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 0.513 Hrs

Ozone Reaction:

OVERALL Ozone Rate Constant = 13.650000 E-17 cm3/molecule-sec

Half-Life = 0.084 Days (at 7E11 mol/cm3)

Half-Life = 2.015 Hrs

Fraction sorbed to airborne particulates (phi):

0.894 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 59.6 L/kg (MCI method)

Log Koc: 1.775 (MCI method)

Koc : 75.58 L/kg (Kow method)

Log Koc: 1.878 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.01):

Log BCF from regression-based method = 0.623 (BCF = 4.201 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -2.0910 days (HL = 0.008109 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.176 (BCF = 1.501)

Log BAF Arnot-Gobas method (upper trophic) = 0.176 (BAF = 1.501)

log Kow used: 1.45 (estimated)

Volatilization from Water:

Henry LC: 2.99E-015 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 3.471E+011 hours (1.446E+010 days)

Half-Life from Model Lake : 3.787E+012 hours (1.578E+011 days)

Removal In Wastewater Treatment:

Total removal: 1.96 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.87 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 2.8e-006 0.68 1000

Water 20.3 900 1000

Soil 79.6 1.8e+003 1000

Sediment 0.0964 8.1e+003 0

Persistence Time: 1.5e+003 hr

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