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CAS Number: 22457-89-2

SMILES : n1c(C)nc(N)c(CN(C(=O))C(C)=C(SC(=O)c2ccccc2)CCOP(O)(O)=O)c1

CHEM :

MOL FOR: C19 H23 N4 O6 P1 S1

MOL WT : 466.45

------------------------------ EPI SUMMARY (v4.00) --------------------------

Physical Property Inputs:

Log Kow (octanol-water): ------

Boiling Point (deg C) : ------

Melting Point (deg C) : ------

Vapor Pressure (mm Hg) : ------

Water Solubility (mg/L): ------

Henry LC (atm-m3/mole) : ------

Log Octanol-Water Partition Coef (SRC):

Log Kow (KOWWIN v1.67 estimate) = 1.10

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPVP v1.43):

Boiling Pt (deg C): 480.00 (Adapted Stein & Brown method)

Melting Pt (deg C): 90.27 (Mean or Weighted MP)

VP(mm Hg,25 deg C): 6.06E-011 (Modified Grain method)

VP (Pa, 25 deg C) : 8.07E-009 (Modified Grain method)

Subcooled liquid VP: 2.58E-010 mm Hg (25 deg C, Mod-Grain method)

: 3.44E-008 Pa (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.41):

Water Solubility at 25 deg C (mg/L): 134.8

log Kow used: 1.10 (estimated)

no-melting pt equation used

Water Sol Estimate from Fragments:

Wat Sol (v1.01 est) = 3.5492e+005 mg/L

ECOSAR Class Program (ECOSAR v1.00):

Class(es) found:

Anilines (Aromatic Amines)

Esters

Vinyl/Allyl Esters

Henrys Law Constant (25 deg C) [HENRYWIN v3.20]:

Bond Method : 1.33E-028 atm-m3/mole (1.35E-023 Pa-m3/mole)

Group Method: Incomplete

For Henry LC Comparison Purposes:

User-Entered Henry LC: not entered

Henrys LC [via VP/WSol estimate using User-Entered or Estimated values]:

HLC: 2.759E-013 atm-m3/mole (2.796E-008 Pa-m3/mole)

VP: 6.06E-011 mm Hg (source: MPBPVP)

WS: 135 mg/L (source: WSKOWWIN)

Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:

Log Kow used: 1.10 (KowWin est)

Log Kaw used: -26.265 (HenryWin est)

Log Koa (KOAWIN v1.10 estimate): 27.365

Log Koa (experimental database): None

Probability of Rapid Biodegradation (BIOWIN v4.10):

Biowin1 (Linear Model) : 0.6846

Biowin2 (Non-Linear Model) : 0.3883

Expert Survey Biodegradation Results:

Biowin3 (Ultimate Survey Model): 1.9264 (months )

Biowin4 (Primary Survey Model) : 3.2082 (weeks )

MITI Biodegradation Probability:

Biowin5 (MITI Linear Model) : -0.5723

Biowin6 (MITI Non-Linear Model): 0.0001

Anaerobic Biodegradation Probability:

Biowin7 (Anaerobic Linear Model): -0.7707

Ready Biodegradability Prediction: NO

Hydrocarbon Biodegradation (BioHCwin v1.01):

Structure incompatible with current estimation method!

Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:

Vapor pressure (liquid/subcooled): 3.44E-008 Pa (2.58E-010 mm Hg)

Log Koa (Koawin est ): 27.365

Kp (particle/gas partition coef. (m3/ug)):

Mackay model : 87.2

Octanol/air (Koa) model: 5.69E+014

Fraction sorbed to airborne particulates (phi):

Junge-Pankow model : 1

Mackay model : 1

Octanol/air (Koa) model: 1

Atmospheric Oxidation (25 deg C) [AopWin v1.92]:

Hydroxyl Radicals Reaction:

OVERALL OH Rate Constant = 118.8631 E-12 cm3/molecule-sec

Half-Life = 0.090 Days (12-hr day; 1.5E6 OH/cm3)

Half-Life = 1.080 Hrs

Ozone Reaction:

OVERALL Ozone Rate Constant = 7.393750 E-17 cm3/molecule-sec

Half-Life = 0.155 Days (at 7E11 mol/cm3)

Half-Life = 3.720 Hrs

Fraction sorbed to airborne particulates (phi):

1 (Junge-Pankow, Mackay avg)

1 (Koa method)

Note: the sorbed fraction may be resistant to atmospheric oxidation

Soil Adsorption Coefficient (KOCWIN v2.00):

Koc : 10.78 L/kg (MCI method)

Log Koc: 1.033 (MCI method)

Koc : 15.2 L/kg (Kow method)

Log Koc: 1.182 (Kow method)

Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v2.00]:

Rate constants can NOT be estimated for this structure!

Bioaccumulation Estimates (BCFBAF v3.00):

Log BCF from regression-based method = 0.393 (BCF = 2.47 L/kg wet-wt)

Log Biotransformation Half-life (HL) = -2.6641 days (HL = 0.002167 days)

Log BCF Arnot-Gobas method (upper trophic) = 0.064 (BCF = 1.159)

Log BAF Arnot-Gobas method (upper trophic) = 0.064 (BAF = 1.159)

log Kow used: 1.10 (estimated)

Volatilization from Water:

Henry LC: 1.33E-028 atm-m3/mole (estimated by Bond SAR Method)

Half-Life from Model River: 9.507E+024 hours (3.961E+023 days)

Half-Life from Model Lake : 1.037E+026 hours (4.322E+024 days)

Removal In Wastewater Treatment:

Total removal: 1.90 percent

Total biodegradation: 0.09 percent

Total sludge adsorption: 1.80 percent

Total to Air: 0.00 percent

(using 10000 hr Bio P,A,S)

Level III Fugacity Model:

Mass Amount Half-Life Emissions

(percent) (hr) (kg/hr)

Air 4.21e-018 1.37 1000

Water 36.3 1.44e+003 1000

Soil 63.6 2.88e+003 1000

Sediment 0.0894 1.3e+004 0

Persistence Time: 1.45e+003 hr

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