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betaine aldehyde
glycine betaine aldehyde

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CAS Number: 7418-61-3Picture of molecule3D/inchi
FDA UNII: DEI7V5X7RB
Nikkaji Web:J413.989E
XlogP3-AA:-0.20 (est)
Molecular Weight:102.15684000
Formula:C5 H12 N O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
betaine aldehyde 95%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for betaine aldehyde usage levels up to:
 not for fragrance use.
 
Recommendation for betaine aldehyde flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :249
National Institute of Allergy and Infectious Diseases:Data
trimethyl(2-oxoethyl)azanium
Chemidplus:0007418613
 
References:
 trimethyl(2-oxoethyl)azanium
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):249
Pubchem (cas):7418-61-3
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Metabolomics Database:Search
KEGG (GenomeNet):C00576
HMDB (The Human Metabolome Database):HMDB01252
FooDB:FDB022513
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ethanaminium, N,N,N-trimethyl-2-oxo-
 glycine betaine aldehyde
 trimethyl(2-oxoethyl)azanium
 

Articles:

PubMed:Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr.
PubMed:Differential levels of metabolites and enzymes related to aroma formation in aromatic indica rice varieties: comparison with non-aromatic varieties.
PubMed:Substitutions of S101 decrease proton and hydride transfers in the oxidation of betaine aldehyde by choline oxidase.
PubMed:Complete genome sequence of endophyte Bacillus flexus KLBMP 4941 reveals its plant growth promotion mechanism and genetic basis for salt tolerance.
PubMed:Betaine Aldehyde Dehydrogenase expression during physiological cardiac hypertrophy induced by pregnancy.
PubMed:Effect of Gamma Irradiation on 2-Acetyl-1-pyrroline Content, GABA Content and Volatile Compounds of Germinated Rice (Thai Upland Rice).
PubMed:Cadmium hampers salt tolerance of Sesuvium portulacastrum.
PubMed:Transcriptomic and Metabolomics Profiling of Phage-Host Interactions between Phage PaP1 andPseudomonas aeruginosa.
PubMed:Cloning and molecular characterization of the betaine aldehyde dehydrogenase involved in the biosynthesis of glycine betaine in white shrimp (Litopenaeus vannamei).
PubMed:Metabolic responses to intestine regeneration in sea cucumbers Apostichopus japonicus.
PubMed:Arabidopsis aldehyde dehydrogenase 10 family members confer salt tolerance through putrescine-derived 4-aminobutyrate (GABA) production.
PubMed:Single base substitution causing the fragrant phenotype and development of a type-specific marker in aromatic coconut (Cocos nucifera).
PubMed:Effects of Betaine Aldehyde Dehydrogenase-Transgenic Soybean on Phosphatase Activities and Rhizospheric Bacterial Community of the Saline-Alkali Soil.
PubMed:Comparative genomics of an endophytic Pseudomonas putida isolated from mango orchard.
PubMed:Hydrogen Sulfide-Mediated Polyamines and Sugar Changes Are Involved in Hydrogen Sulfide-Induced Drought Tolerance in Spinacia oleracea Seedlings.
PubMed:Aroma volatile analyses and 2AP characterization at various developmental stages in Basmati and Non-Basmati scented rice (Oryza sativa L.) cultivars.
PubMed:Potential Metabolic Biomarkers to Identify Interstitial Lung Abnormalities.
PubMed:Cloning and characterization of a novel betaine aldehyde dehydrogenase gene from Suaeda corniculata.
PubMed:Thirty-three years of 2-acetyl-1-pyrroline, a principal basmati aroma compound in scented rice (Oryza sativa L.): a status review.
PubMed:Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool.
PubMed:Genetic transformation and expression of transgenic lines of Populus x euramericana with insect-resistance and salt-tolerance genes.
PubMed:Proteomic and phosphoproteomic analysis reveals the response and defense mechanism in leaves of diploid wheat T. monococcum under salt stress and recovery.
PubMed:Osmotic stress response in Acinetobacter baylyi: identification of a glycine-betaine biosynthesis pathway and regulation of osmoadaptive choline uptake and glycine-betaine synthesis through a choline-responsive BetI repressor.
PubMed:Reversible, partial inactivation of plant betaine aldehyde dehydrogenase by betaine aldehyde: mechanism and possible physiological implications.
PubMed:Proteomic Analysis of Isogenic Rice Reveals Proteins Correlated with Aroma Compound Biosynthesis at Different Developmental Stages.
PubMed:Osmotic stress response in Acinetobacter baylyi: Identification of a glycine-betaine biosynthesis pathway and regulation of osmoadaptive choline uptake and glycine betaine synthesis through a choline-responsive BetI repressor.
PubMed:Fluorescence of the Flavin group in choline oxidase. Insights and analytical applications for the determination of choline and betaine aldehyde.
PubMed:Comparative Characterization of Aroma Volatiles and Related Gene Expression Analysis at Vegetative and Mature Stages in Basmati and Non-Basmati Rice (Oryza sativa L.) Cultivars.
PubMed:SpBADH of the halophyte Sesuvium portulacastrum strongly confers drought tolerance through ROS scavenging in transgenic Arabidopsis.
PubMed:Characterization of the superoxide dismutase genes of the halophyte Suaeda maritima in Japan and Egypt.
PubMed:Resequencing Reveals Different Domestication Rate for BADH1 and BADH2 in Rice (Oryza sativa).
PubMed:Molecular characterization and organ-specific expression of the gene that encodes betaine aldehyde dehydrogenase from the white shrimp Litopenaeus vannamei in response to osmotic stress.
PubMed:Overexpression of ALDH10A8 and ALDH10A9 Genes Provides Insight into Their Role in Glycine Betaine Synthesis and Affects Primary Metabolism in Arabidopsis thaliana.
PubMed:A single base substitution in BADH/AMADH is responsible for fragrance in cucumber (Cucumis sativus L.), and development of SNAP markers for the fragrance.
PubMed:Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade.
PubMed:Altered Proteome of Burkholderia pseudomallei Colony Variants Induced by Exposure to Human Lung Epithelial Cells.
PubMed:Functional and expression analyses of two kinds of betaine aldehyde dehydrogenases in a glycinebetaine-hyperaccumulating graminaceous halophyte, Leymus chinensis.
PubMed:Chemical intervention in bacterial lignin degradation pathways: Development of selective inhibitors for intradiol and extradiol catechol dioxygenases.
PubMed:Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.
PubMed:Low-temperature conditioning alleviates chilling injury in loquat fruit and regulates glycine betaine content and energy status.
PubMed:Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology.
PubMed:Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy.
PubMed:Identification of the catalytic base for alcohol activation in choline oxidase.
PubMed:Systematic phenotypic screen of Arabidopsis peroxisomal mutants identifies proteins involved in β-oxidation.
PubMed:Synthetic approach for unsaturated precursors for parahydrogen induced polarization of choline and its analogs.
PubMed:RNAi-directed downregulation of betaine aldehyde dehydrogenase 1 (OsBADH1) results in decreased stress tolerance and increased oxidative markers without affecting glycine betaine biosynthesis in rice (Oryza sativa).
PubMed:Heterologous expression of betaine aldehyde dehydrogenase gene from Ammopiptanthus nanus confers high salt and heat tolerance to Escherichia coli.
PubMed:Exploring the evolutionary route of the acquisition of betaine aldehyde dehydrogenase activity by plant ALDH10 enzymes: implications for the synthesis of the osmoprotectant glycine betaine.
PubMed:Structure-based mutational studies of substrate inhibition of betaine aldehyde dehydrogenase BetB from Staphylococcus aureus.
PubMed:Synthesis of the first water-soluble hemicryptophane host: selective recognition of choline in aqueous medium.
PubMed:Quantification of rate constants for successive enzymatic reactions with DNP hyperpolarized MR.
PubMed:Cloning and sequence analysis of the safflower betaine aldehyde dehydrogenase gene.
PubMed:Combating photooxidative stress in green hairy roots of Daucus carota cultivated under light irradiation.
PubMed:A proteomic study of rice cultivar TNG67 and its high aroma mutant SA0420.
PubMed:Characterization of betaine aldehyde dehydrogenase (BetB) as an essential virulence factor of Brucella abortus.
PubMed:Comparative quantitative analysis of headspace volatiles and their association with BADH2 marker in non-basmati scented, basmati and non-scented rice (Oryza sativa L.) cultivars of India.
PubMed:Gene discovery and functional marker development for fragrance in sorghum (Sorghum bicolor (L.) Moench).
PubMed:In vitro visualization of betaine aldehyde synthesis and oxidation using hyperpolarized magnetic resonance spectroscopy.
PubMed:Glycine betaine-mediated potentiation of HSP gene expression involves calcium signaling pathways in tobacco exposed to NaCl stress.
PubMed:Pathway of glycine betaine biosynthesis in Aspergillus fumigatus.
PubMed:Constitutive and salt-inducible expression of SlBADH gene in transgenic tomato (Solanum lycopersicum L. cv. Micro-Tom) enhances salt tolerance.
PubMed:Potassium and ionic strength effects on the conformational and thermal stability of two aldehyde dehydrogenases reveal structural and functional roles of K⁺-binding sites.
PubMed:The freshwater cyanobacterium Anabaena doliolum transformed with ApGSMT-DMT exhibited enhanced salt tolerance and protection to nitrogenase activity, but became halophilic.
PubMed:Purification and characterization of an alkaliphilic choline oxidase of Fusarium oxysporum.
PubMed:Serratia entomophila bet gene induction and the impact of glycine betaine accumulation on desiccation tolerance.
PubMed:Chemical analysis of complex organic mixtures using reactive nanospray desorption electrospray ionization mass spectrometry.
PubMed:[Functional divergence of betaine aldehyde dehydrogenase genes in Populus euphratica].
PubMed:Improved tolerance to various abiotic stresses in transgenic sweet potato (Ipomoea batatas) expressing spinach betaine aldehyde dehydrogenase.
PubMed:Rice choline monooxygenase (OsCMO) protein functions in enhancing glycine betaine biosynthesis in transgenic tobacco but does not accumulate in rice (Oryza sativa L. ssp. japonica).
PubMed:Dissecting substrate specificity of two rice BADH isoforms: Enzyme kinetics, docking and molecular dynamics simulation studies.
PubMed:Modulation Role of abscisic acid (ABA) on growth, water relations and glycinebetaine metabolism in two maize (Zea mays L.) cultivars under drought stress.
PubMed:In silico assessment of the potential allergenicity of transgenes used for the development of GM food crops.
PubMed:Amino acid residues critical for the specificity for betaine aldehyde of the plant ALDH10 isoenzyme involved in the synthesis of glycine betaine.
PubMed:Purification, crystallization and preliminary X-ray analysis of recombinant betaine aldehyde dehydrogenase 2 (OsBADH2), a protein involved in jasmine aroma, from Thai fragrant rice (Oryza sativa L.).
PubMed:Biochemical and enzymatic study of rice BADH wild-type and mutants: an insight into fragrance in rice.
PubMed:Isolation and characterization of a novel peroxisomal choline monooxygenase in barley.
PubMed:Carboxylate and aromatic active-site residues are determinants of high-affinity binding of ω-aminoaldehydes to plant aminoaldehyde dehydrogenases.
PubMed:Novel NADPH-cysteine covalent adduct found in the active site of an aldehyde dehydrogenase.
PubMed:Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity.
PubMed:Inactivation of porcine kidney betaine aldehyde dehydrogenase by hydrogen peroxide.
PubMed:Isolation of choline monooxygenase (CMO) gene from Salicornia europaea and enhanced salt tolerance of transgenic tobacco with CMO genes.
PubMed:Inhibition of porcine kidney betaine aldehyde dehydrogenase by hydrogen peroxide.
PubMed:Aldehyde Dehydrogenases in Arabidopsis thaliana: Biochemical Requirements, Metabolic Pathways, and Functional Analysis.
PubMed:Betaine aldehyde dehydrogenase genes from Arabidopsis with different sub-cellular localization affect stress responses.
PubMed:A SNP in GmBADH2 gene associates with fragrance in vegetable soybean variety "Kaori" and SNAP marker development for the fragrance.
PubMed:The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial growth.
PubMed:Nutritional, biochemical, and pharmaceutical potential of proteins and peptides from jatropha: review.
PubMed:Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress.
PubMed:Molecular imaging of adrenal gland by desorption electrospray ionization mass spectrometry.
PubMed:Choline metabolism in glycinebetaine accumulating and non-accumulating near-isogenic lines of Zea mays and Sorghum bicolor.
PubMed:Ambient analysis of saturated hydrocarbons using discharge-induced oxidation in desorption electrospray ionization.
PubMed:OsBADH1 is possibly involved in acetaldehyde oxidation in rice plant peroxisomes.
PubMed:Imaging of lipids in atheroma by desorption electrospray ionization mass spectrometry.
PubMed:Kinetic and structural features of betaine aldehyde dehydrogenases: mechanistic and regulatory implications.
PubMed:Rapid, direct analysis of cholesterol by charge labeling in reactive desorption electrospray ionization.
PubMed:The origin and evolution of fragrance in rice (Oryza sativa L.).
PubMed:Preferential accumulation of betaine uncoupled to choline monooxygenase in young leaves of sugar beet--importance of long-distance translocation of betaine under normal and salt-stressed conditions.
PubMed:Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase.
PubMed:Genetic and molecular basis of fragrance in rice.
PubMed:Betaine aldehyde dehydrogenase in plants.
PubMed:Synthesis of glycine betaine from choline in the moderate halophile Halobacillus halophilus: co-regulation of two divergent, polycistronic operons.
PubMed:Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases.
PubMed:Reaction of the catalytic cysteine of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with arsenite-BAL and phenylarsine oxide.
PubMed:The crystal structure of a ternary complex of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa Provides new insight into the reaction mechanism and shows a novel binding mode of the 2'-phosphate of NADP+ and a novel cation binding site.
PubMed:[Overexpression of Spinacia oleracea betaine aldehyde dehydrogenase (SoBADH) gene confers the salt and cold tolerant in Gossypium hirsutum L].
PubMed:RNAi-directed downregulation of OsBADH2 results in aroma (2-acetyl-1-pyrroline) production in rice (Oryza sativa L.).
PubMed:Heterologous expression and characterization of choline oxidase from the soil bacterium Arthrobacter nicotianae.
PubMed:Inactivation of an aminoaldehyde dehydrogenase is responsible for fragrance in rice.
PubMed:Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-acetyl-1-pyrroline, a major component in rice fragrance.
PubMed:On the role of histidine 351 in the reaction of alcohol oxidation catalyzed by choline oxidase.
PubMed:Genetic tools for allelic replacement in Burkholderia species.
PubMed:Characterization of the major fragance gene from an aromatic japonica rice and analysis of its diversity in Asian cultivated rice.
PubMed:Plastid-expressed choline monooxygenase gene improves salt and drought tolerance through accumulation of glycine betaine in tobacco.
PubMed:Enzymatic characterization of peroxisomal and cytosolic betaine aldehyde dehydrogenases in barley.
PubMed:Screening of genes regulated by cold shock in Shewanella piezotolerans WP3 and time course expression of cold-regulated genes.
PubMed:Complex, unusual conformational changes in kidney betaine aldehyde dehydrogenase suggested by chemical modification with disulfiram.
PubMed:Genetic engineering of the biosynthesis of glycinebetaine leads to increased tolerance of photosynthesis to salt stress in transgenic tobacco plants.
PubMed:Co-ordinate expression of glycine betaine synthesis genes linked by the FMDV 2A region in a single open reading frame in Pichia pastoris.
PubMed:Functional analysis of BADH gene promoter from Suaeda liaotungensis K.
PubMed:Functional defect at the rice choline monooxygenase locus from an unusual post-transcriptional processing is associated with the sequence elements of short-direct repeats.
PubMed:Proteomic analyses indicate induction of hepatic carbonyl reductase/20beta-hydroxysteroid dehydrogenase B in rainbow trout exposed to sewage effluent.
PubMed:An unusual posttranscriptional processing in two betaine aldehyde dehydrogenase loci of cereal crops directed by short, direct repeats in response to stress conditions.
PubMed:The accumulation and synthesis of betaine in winter skate (Leucoraja ocellata).
PubMed:Inhibition of choline oxidase by quinoid dyes.
PubMed:Ethanol attenuates Aldh9 mRNA expression in Japanese medaka (Oryzias latipes) embryogenesis.
PubMed:The gene for fragrance in rice.
PubMed:The fgr gene responsible for rice fragrance was restricted within 69kb.
PubMed:Halotolerant cyanobacterium Aphanothece halophytica contains a betaine transporter active at alkaline pH and high salinity.
PubMed:Accumulation of glycinebetaine in rice plants that overexpress choline monooxygenase from spinach and evaluation of their tolerance to abiotic stress.
PubMed:[Isolation of BADH gene promoter from Suaeda liaotungensis and its sequence analysis].
PubMed:The accumulation of methylamine counteracting solutes in elasmobranchs with differing levels of urea: a comparison of marine and freshwater species.
PubMed:Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde.
PubMed:Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa.
PubMed:Oxygen- and temperature-dependent kinetic isotope effects in choline oxidase: correlating reversible hydride transfer with environmentally enhanced tunneling.
PubMed:Betaine aldehyde dehydrogenase from Pseudomonas aeruginosa: cloning, over-expression in Escherichia coli, and regulation by choline and salt.
PubMed:Isolation of cDNA and enzymatic properties of betaine aldehyde dehydrogenase from Zoysia tenuifolia.
PubMed:Cloning, sequencing and salt induced expression of PEAMT and BADH in oilseed rape (Brassica napus).
PubMed:Purification and properties of betaine aldehyde dehydrogenase with high affinity for NADP from Arthrobacter globiformis.
PubMed:[Rapid amplification of 3' cDNA end of Suaeda liaotungensis betaine aldehyde dehydrogenase using one-step PCR].
PubMed:Identification of adaptation-specific differences in mRNA expression of sessile and pedunculate oak based on osmotic-stress-induced genes.
PubMed:Site-directed mutagenesis and homology modeling indicate an important role of cysteine 439 in the stability of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.
PubMed:Genetic engineering of the biosynthesis of glycinebetaine enhances photosynthesis against high temperature stress in transgenic tobacco plants.
PubMed:On the catalytic mechanism of choline oxidase.
PubMed:On the catalytic role of the conserved active site residue His466 of choline oxidase.
PubMed:Changes in glycine betaine and related enzyme contents in Amaranthus tricolor under salt stress.
PubMed:[Saline tolerance white clover transformed with the betaine aldehyde dehyrogenase gene by Agrobacterium tumefaciens].
PubMed:Crystal structure and kinetics identify Escherichia coli YdcW gene product as a medium-chain aldehyde dehydrogenase.
PubMed:The trimethylammonium headgroup of choline is a major determinant for substrate binding and specificity in choline oxidase.
PubMed:Osmotic stress in barley regulates expression of a different set of genes than salt stress does.
PubMed:Plastid-expressed betaine aldehyde dehydrogenase gene in carrot cultured cells, roots, and leaves confers enhanced salt tolerance.
PubMed:Sulfoacetate generated by Rhodopseudomonas palustris from taurine.
PubMed:Abscisic acid is involved in the water stress-induced betaine accumulation in pear leaves.
PubMed:Spectroscopic and kinetic properties of recombinant choline oxidase from Arthrobacter globiformis.
PubMed:Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: a bacterial enzyme involved in osmotic stress tolerance.
PubMed:Distinct but parallel evolutionary patterns between alcohol and aldehyde dehydrogenases: addition of fish/human betaine aldehyde dehydrogenase divergence.
PubMed:Molecular cloning and characterization of betaine aldehyde dehydrogenase gene from Suaeda liaotungensis and its use in improved tolerance to salinity in transgenic tobacco.
PubMed:pH and deuterium kinetic isotope effects studies on the oxidation of choline to betaine-aldehyde catalyzed by choline oxidase.
PubMed:The Sinorhizobium meliloti glycine betaine biosynthetic genes (betlCBA) are induced by choline and highly expressed in bacteroids.
PubMed:Structural characterization and mapping of the covalently linked FAD cofactor in choline oxidase from Arthrobacter globiformis.
PubMed:Purification and properties of betaine aldehyde dehydrogenase from Avena sativa.
PubMed:Cloning, expression, and purification of choline dehydrogenase from the moderate halophile Halomonas elongata.
PubMed:Kinetic mechanism of choline oxidase from Arthrobacter globiformis.
PubMed:Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase.
PubMed:Inactivation of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa and Amaranthus hypochondriacus L. leaves by disulfiram.
PubMed:Monovalent cations requirements for the stability of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, porcine kidney and amaranth leaves.
PubMed:Ligand-induced conformational changes of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa and Amaranthus hypochondriacus L. leaves affecting the reactivity of the catalytic thiol.
PubMed:Purification and properties of aminoaldehyde dehydrogenase from Avena sativa.
PubMed:Enhanced stress tolerance in Escherichia coli and Nicotiana tabacum expressing a betaine aldehyde dehydrogenase/choline dehydrogenase fusion protein.
PubMed:Isolating the promoter of a stress-induced gene encoding betaine aldehyde dehydrogenase from the halophyte Atriplex centralasiatica Iljin.
PubMed:Glu 103 Gln site-directed mutation causes an alteration in physical properties of spinach betaine aldehyde dehydrogenase.
PubMed:Functional characterization of betaine/proline transporters in betaine-accumulating mangrove.
PubMed:Novel ABA- and dehydration-inducible aldehyde dehydrogenase genes isolated from the resurrection plant Craterostigma plantagineum and Arabidopsis thaliana.
PubMed:Modulation of the reactivity of the essential cysteine residue of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.
PubMed:Measurement of free choline in plant leaves by capillary electrophoresis.
PubMed:Actinopolyspora halophila has two separate pathways for betaine synthesis.
PubMed:An isozyme of betaine aldehyde dehydrogenase in barley.
PubMed:Isolation of a choline monooxygenase cDNA clone from Amaranthus tricolor and its expressions under stress conditions.
PubMed:Purification of a heterodimeric betaine aldehyde dehydrogenase from wild amaranth plants subjected to water deficit.
PubMed:Marker free transgenic plants: engineering the chloroplast genome without the use of antibiotic selection.
PubMed:Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
PubMed:Antibiotic-free chloroplast genetic engineering - an environmentally friendly approach.
PubMed:[Cloning and characterization of CMO gene from Atriplex hortensis].
PubMed:Betaine aldehyde dehydrogenase from rat liver mitochondrial matrix.
PubMed:Complexes of NADH with betaine aldehyde dehydrogenase from leaves of the plant Amaranthus hypochondriacus L.
PubMed:Molecular cloning and functional characterization of two kinds of betaine-aldehyde dehydrogenase in betaine-accumulating mangrove Avicennia marina (Forsk.) Vierh.
PubMed:Choline import into chloroplasts limits glycine betaine synthesis in tobacco: analysis of plants engineered with a chloroplastic or a cytosolic pathway.
PubMed:Overproduction of spinach betaine aldehyde dehydrogenase in Escherichia coli. Structural and functional properties of wild-type, mutants and E. coli enzymes.
PubMed:Steady-state kinetic mechanism of the NADP+- and NAD+-dependent reactions catalysed by betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.
PubMed:Betaine aldehyde, betaine, and choline levels in rat livers during ethanol metabolism.
PubMed:Characterisation of a homogeneous plant aminoaldehyde dehydrogenase.
PubMed:Improved tolerance to salinity and low temperature in transgenic tobacco producing glycine betaine.
PubMed:Kinetic study of porcine kidney betaine aldehyde dehydrogenase.
PubMed:Genes for the synthesis of the osmoprotectant glycine betaine from choline in the moderately halophilic bacterium Halomonas elongata DSM 3043, USA.
PubMed:Choline dehydrogenase kinetics contribute to glycine betaine regulation differences in chesapeake bay and atlantic oysters.
PubMed:Betaine aldehyde dehydrogenase kinetics partially account for oyster population differences in glycine betaine synthesis.
PubMed:Upregulation of stress response genes and ABC transporters in anaerobic stationary-phase Mycobacterium smegmatis.
PubMed:Evidence for mitochondrial localization of betaine aldehyde dehydrogenase in rat liver: purification, characterization, and comparison with human cytoplasmic E3 isozyme.
PubMed:Aldehyde dehydrogenase from rat intestinal mucosa: purification and characterization of an isozyme with high affinity for gamma-aminobutyraldehyde.
PubMed:Structure and function of betaine aldehyde dehydrogenase. An enzyme within the multienzyme aldehyde dehydrogenase system.
PubMed:Immunolocalization of betaine aldehyde dehydrogenase in porcine kidney.
PubMed:Occurrence of choline and glycine betaine uptake and metabolism in the family rhizobiaceae and their roles in osmoprotection
PubMed:Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.
PubMed:Direct fermentation of 2-keto-L-gulonic acid in recombinant Gluconobacter oxydans.
PubMed:The choline-converting pathway in Staphylococcus xylosus C2A: genetic and physiological characterization.
PubMed:Rapid purification and properties of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa.
PubMed:The endogenous choline supply limits glycine betaine synthesis in transgenic tobacco expressing choline monooxygenase.
PubMed:Structure of betaine aldehyde dehydrogenase at 2.1 A resolution.
PubMed:Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth. Expression in leaves under short-term exposure to osmotic stress or abscisic acid.
PubMed:Presence of a gene encoding choline sulfatase in Sinorhizobium meliloti bet operon: choline-O-sulfate is metabolized into glycine betaine.
PubMed:Porcine kidney betaine aldehyde dehydrogenase: purification and properties.
PubMed:Genetic structure of the bphG gene encoding 2-hydroxymuconic semialdehyde dehydrogenase of Achromobacter xylosoxidans KF701.
PubMed:Tissue distribution of human aldehyde dehydrogenase E3 (ALDH9): comparison of enzyme activity with E3 protein and mRNA distribution.
PubMed:Expression of betaine aldehyde dehydrogenase gene and salinity tolerance in rice transgenic plants.
PubMed:Glycine betaine aldehyde dehydrogenase from Bacillus subtilis: characterization of an enzyme required for the synthesis of the osmoprotectant glycine betaine.
PubMed:Substrate inhibition by betaine aldehyde of betaine aldehyde dehydrogenase from leaves of Amaranthus hypochondriacus L.
PubMed:Cimetidine and other H2-receptor antagonists as inhibitors of human E3 aldehyde dehydrogenase.
PubMed:Expression of a betaine aldehyde dehydrogenase gene in rice, a glycinebetaine nonaccumulator, and possible localization of its protein in peroxisomes.
PubMed:Transgenically Expressed Betaine Aldehyde Dehydrogenase Efficiently Catalyzes Oxidation of Dimethylsulfoniopropionaldehyde and [omega]-Aminoaldehydes.
PubMed:Molecular characterization of the bet genes encoding glycine betaine synthesis in Sinorhizobium meliloti 102F34.
PubMed:Choline monooxygenase, an unusual iron-sulfur enzyme catalyzing the first step of glycine betaine synthesis in plants: prosthetic group characterization and cDNA cloning.
PubMed:Kinetic Properties of Choline Dehydrogenase.
PubMed:Expression of the spinach betaine aldehyde dehydrogenase (BADH) gene in transgenic tobacco plants.
PubMed:Effects of glycerol on the kinetic properties of betaine aldehyde dehydrogenase.
PubMed:Human aldehyde dehydrogenase E3. Further characterization.
PubMed:Molecular characterization of mutants affected in the osmoprotectant-dependent induction of phospholipase C in Pseudomonas aeruginosa PAO1.
PubMed:Betaine-aldehyde dehydrogenase from amaranth leaves efficiently catalyzes the NAD-dependent oxidation of dimethylsulfoniopropionaldehyde to dimethylsulfoniopropionate.
PubMed:Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes.
PubMed:Evidence That the Pathway of Dimethylsulfoniopropionate Biosynthesis Begins in the Cytosol and Ends in the Chloroplast.
PubMed:Betaine aldehyde dehydrogenase in sorghum.
PubMed:The complex bet promoters of Escherichia coli: regulation by oxygen (ArcA), choline (BetI), and osmotic stress.
PubMed:Determination of choline dehydrogenase activity along the rat nephron.
PubMed:Osmotic regulation of the betaine metabolism in immortalized renal cells.
PubMed:Human aldehyde dehydrogenase E3 isozyme is a betaine aldehyde dehydrogenase.
PubMed:Assay, Purification, and Partial Characterization of Choline Monooxygenase from Spinach.
PubMed:Synechococcus sp. PCC7942 Transformed with Escherichia coli bet Genes Produces Glycine Betaine from Choline and Acquires Resistance to Salt Stress.
PubMed:Expression of the betaine aldehyde dehydrogenase gene in barley in response to osmotic stress and abscisic acid.
PubMed:Production of the Escherichia coli betaine-aldehyde dehydrogenase, an enzyme required for the synthesis of the osmoprotectant glycine betaine, in transgenic plants.
PubMed:Use of hydrophobic chromatography for purification of the membrane-located choline dehydrogenase from a Pseudomonas strain.
PubMed:Bicarbonate dependency of betaine synthesis in cultured LLC-PK1 cells.
PubMed:Utilization of osmoprotective compounds by hybridoma cells exposed to hyperosmotic stress.
PubMed:Osmoprotective compounds in the Plumbaginaceae: a natural experiment in metabolic engineering of stress tolerance.
PubMed:Metabolic engineering of glycine betaine synthesis: plant betaine aldehyde dehydrogenases lacking typical transit peptides are targeted to tobacco chloroplasts where they confer betaine aldehyde resistance.
PubMed:Human aldehyde dehydrogenase. cDNA cloning and primary structure of the enzyme that catalyzes dehydrogenation of 4-aminobutyraldehyde.
PubMed:Betaine-aldehyde dehydrogenase from leaves of Amaranthus hypochondriacus L. exhibits an Iso Ordered Bi Bi steady state mechanism.
PubMed:Measurement of the formation of betaine aldehyde and betaine in rat liver mitochondria by a high pressure liquid chromatography-radioenzymatic assay.
PubMed:CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution.
PubMed:Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde.
PubMed:Choline transport in Fusarium graminearum A 3/5.
PubMed:Inhibitors of choline transport in alveolar type II epithelial cells.
PubMed:Salt-inducible betaine aldehyde dehydrogenase from sugar beet: cDNA cloning and expression.
PubMed:Characterization of an osmoregulated periplasmic glycine betaine-binding protein in Azospirillum brasilense sp7.
PubMed:Characterization of an Escherichia coli gene encoding betaine aldehyde dehydrogenase (BADH): structural similarity to mammalian ALDHs and a plant BADH.
PubMed:DNA sequence and analysis of the bet genes encoding the osmoregulatory choline-glycine betaine pathway of Escherichia coli.
PubMed:Betaine deficiency in maize : complementation tests and metabolic basis.
PubMed:Identification of an osmotically induced periplasmic glycine betaine-binding protein from Rhizobium meliloti.
PubMed:Choline oxidase, a catabolic enzyme in Arthrobacter pascens, facilitates adaptation to osmotic stress in Escherichia coli.
PubMed:Identification of the mouse aldehyde dehydrogenases important in aldophosphamide detoxification.
PubMed:Purification and characterization of osmoregulatory betaine aldehyde dehydrogenase of Escherichia coli.
PubMed:Molecular cloning of a plant betaine-aldehyde dehydrogenase, an enzyme implicated in adaptation to salinity and drought.
PubMed:Formation of trimethylamine from dietary choline by Streptococcus sanguis I, which colonizes the mouth.
PubMed:Comparative biochemical and immunological studies of the glycine betaine synthesis pathway in diverse families of dicotyledons.
PubMed:Betaine aldehyde dehydrogenase from spinach leaves: purification, in vitro translation of the mRNA, and regulation by salinity.
PubMed:Evidence for a ferredoxin-dependent choline monooxygenase from spinach chloroplast stroma.
PubMed:Oxygen-18 and deuterium labeling studies of choline oxidation by spinach and sugar beet.
PubMed:Molecular cloning, physical mapping and expression of the bet genes governing the osmoregulatory choline-glycine betaine pathway of Escherichia coli.
PubMed:Betaine aldehyde dehydrogenase polymorphism in spinach: genetic and biochemical characterization.
PubMed:Choline oxidation by intact spinach chloroplasts.
PubMed:Determination of Betaines by Fast Atom Bombardment Mass Spectrometry : Identification of Glycine Betaine Deficient Genotypes of Zea mays.
PubMed:Purification of betaine-aldehyde dehydrogenase from spinach leaves and preparation of its antibody.
PubMed:Betaine aldehyde oxidation by spinach chloroplasts.
PubMed:Selection, mapping, and characterization of osmoregulatory mutants of Escherichia coli blocked in the choline-glycine betaine pathway.
PubMed:Choline-glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli.
PubMed:Betaine synthesis in chenopods: Localization in chloroplasts.
PubMed:Human liver alcohol dehydrogenase isozymes: reduction of aldehydes and ketones.
PubMed:Mechanisms of aldehyde-induced adenosinetriphosphatase activities of kinases.
PubMed:A novel method for determining rate constants for dehydration of aldehyde hydrates.
PubMed:Spectroscopic studies on the photoreaction of choline oxidase, a flavoprotein, with covalently bound flavin.
PubMed:Radiotracer evidence implicating phosphoryl and phosphatidyl bases as intermediates in betaine synthesis by water-stressed barley leaves.
PubMed:Developmental changes in rat blood choline concentration.
PubMed:Betaine accumulation and betaine-aldehyde dehydrogenase in spinach leaves.
PubMed:Translocation and metabolism of glycine betaine by barley plants in relation to water stress.
PubMed:A novel purification and some properties of rat liver mitochondrial choline dehydrogenase.
PubMed:Betaine Synthesis from Radioactive Precursors in Attached, Water-stressed Barley Leaves.
PubMed:Identification and properties of the prosthetic group of choline oxidase from Alcaligenes sp.
PubMed:Purification and characterization of choline oxidase from Arthrobacter globiformis.
PubMed:Oxidative pathway of choline to betaine in the soluble fraction prepared from Arthrobacter globiformis.
PubMed:Partial purification and properties of a phenobarbital-induced aldehyde dehydrogenase of rat liver.
PubMed:Control of choline oxidation by rat-liver mitochondria.
PubMed:Different forms of rat liver aldehyde dehydrogenase and their subcellular distribution.
PubMed:[A spectrophotometric method for the determination of serum cholinesterase variants with succinyl choline as substrate (author's transl)].
PubMed:Choline and betaine aldehyde oxidation by rat liver mitochondria.
PubMed:Estimation of choline and betaine aldehyde dehydrogenase activities in rat liver mitochondria by three independent methods.
PubMed:Utilization of betaine aldehyde by choline (chol-) mutants of Neurospora crassa.
PubMed:Betaine aldehyde dehydrogenase: assay and partial purification.
PubMed:Inability of rat-liver mitochondria to oxidize betaine aldehyde.
PubMed:The oxidation of betaine aldehyde by betaine aldehyde dehydrogenase.
PubMed:Factors influencing betaine aldehyde oxidase activity of rat livers.
PubMed:Intracellular distribution of betaine aldehyde oxidase.
PubMed:Effect of aminopterin on choline, betaine aldehyde, and betaine metabolism.
 
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