Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Soluble in: |
| water, 1.213e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for neoglucobrassicin usage levels up to: | | not for fragrance use.
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Recommendation for neoglucobrassicin flavor usage levels up to: |
| not for flavor use.
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Safety References:
EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :9576416 |
National Institute of Allergy and Infectious Diseases:Data |
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1Z)-2-(1-methoxyindol-3-yl)-N-sulfooxyethanimidothioate |
Chemidplus:0005187848 |
References:
| [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1Z)-2-(1-methoxyindol-3-yl)-N-sulfooxyethanimidothioate |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 9576416 |
Pubchem (cas): | 5187-84-8 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
beta-D- | glucopyranose, 1-thio-, 1-(1-methoxy-N-(sulfooxy)-1H-indole-3-ethanimidate) | 1- | methoxy-3-indolylmethylglucosinolate | [(2S,3R,4S,5S,6R)-3,4,5- | trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1Z)-2-(1-methoxyindol-3-yl)-N-sulfooxyethanimidothioate |
Articles:
PubMed:Molecular characterization of glucosinolates and carotenoid biosynthetic genes in Chinese cabbage (Brassica rapaL. ssp.pekinensis). |
PubMed:Synthesis of aromatic and indole alpha-glucosinolates. |
PubMed:Rapid and Efficient Desulfonation Method for the Analysis of Glucosinolates by High-Resolution Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. |
PubMed:UVA, UVB Light, and Methyl Jasmonate, Alone or Combined, Redirect the Biosynthesis of Glucosinolates, Phenolics, Carotenoids, and Chlorophylls in Broccoli Sprouts. |
PubMed:The ability to manipulate plant glucosinolates and nutrients explains the better performance ofBemisia tabaciMiddle East-Asia Minor 1 than Mediterranean on cabbage plants. |
PubMed:Preferentially enhancing anti-cancer isothiocyanates over glucosinolates in broccoli sprouts: How NaCl and salicylic acid affect their formation. |
PubMed:Fermentation-Assisted Extraction of Isothiocyanates from Brassica Vegetable Using Box-Behnken Experimental Design. |
PubMed:Exogenous Methyl Jasmonate and Salicylic Acid Induce Subspecies-Specific Patterns of Glucosinolate Accumulation and Gene Expression in Brassica oleracea L. |
PubMed:Effects of seed priming, salinity and methyl jasmonate treatment on bioactive composition of Brassica oleracea var. capitata (white and red varieties) sprouts. |
PubMed:Transcriptome and Metabolome Analyses of Glucosinolates in Two Broccoli Cultivars Following Jasmonate Treatment for the Induction of Glucosinolate Defense to Trichoplusia ni (Hübner). |
PubMed:Expression Profiling of Glucosinolate Biosynthetic Genes in Brassica oleracea L. var. capitata Inbred Lines Reveals Their Association with Glucosinolate Content. |
PubMed:Plants as Biofactories: Postharvest Stress-Induced Accumulation of Phenolic Compounds and Glucosinolates in Broccoli Subjected to Wounding Stress and Exogenous Phytohormones. |
PubMed:Production of glucosinolates, phenolic compounds and associated gene expression profiles of hairy root cultures in turnip (Brassica rapa ssp. rapa). |
PubMed:Glucosinolates Are Mainly Absorbed Intact in Germfree and Human Microbiota-Associated Mice. |
PubMed:Leaf and root glucosinolate profiles of Chinese cabbage (Brassica rapa ssp. pekinensis) as a systemic response to methyl jasmonate and salicylic acid elicitation. |
PubMed:Development and validation of a liquid chromatography-tandem mass spectrometry method to determine intact glucosinolates in bee pollen. |
PubMed:Metabolomic assessment reveals an elevated level of glucosinolate content in CaCl₂ treated broccoli microgreens. |
PubMed:Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS. |
PubMed:Optimization of pulsed electric field pre-treatments to enhance health-promoting glucosinolates in broccoli flowers and stalk. |
PubMed:Exogenous methyl jasmonate treatment increases glucosinolate biosynthesis and quinone reductase activity in kale leaf tissue. |
PubMed:Variation in broccoli cultivar phytochemical content under organic and conventional management systems: implications in breeding for nutrition. |
PubMed:Enhancement of broccoli indole glucosinolates by methyl jasmonate treatment and effects on prostate carcinogenesis. |
PubMed:Variation in bioactive content in broccoli (Brassica oleracea var. italica) grown under conventional and organic production systems. |
PubMed:Functional identification of genes responsible for the biosynthesis of 1-methoxy-indol-3-ylmethyl-glucosinolate in Brassica rapa ssp. chinensis. |
PubMed:Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently. |
PubMed:High mutagenic activity of juice from pak choi (Brassica rapa ssp. chinensis) sprouts due to its content of 1-methoxy-3-indolylmethyl glucosinolate, and its enhancement by elicitation with methyl jasmonate. |
PubMed:Optimized extraction, separation and quantification of twelve intact glucosinolates in broccoli leaves. |
PubMed:Identification and quantification of protein adducts formed by metabolites of 1-methoxy-3-indolylmethyl glucosinolate in vitro and in mouse models. |
PubMed:Optimization of methyl jasmonate application to broccoli florets to enhance health-promoting phytochemical content. |
PubMed:A secondary metabolite of Brassicales, 1-methoxy-3-indolylmethyl glucosinolate, as well as its degradation product, 1-methoxy-3-indolylmethyl alcohol, forms DNA adducts in the mouse, but in varying tissues and cells. |
PubMed:Methyl jasmonate and 1-methylcyclopropene treatment effects on quinone reductase inducing activity and post-harvest quality of broccoli. |
PubMed:Influence of seasonal variation and methyl jasmonate mediated induction of glucosinolate biosynthesis on quinone reductase activity in broccoli florets. |
PubMed:MYB transcription factors regulate glucosinolate biosynthesis in different organs of Chinese cabbage (Brassica rapa ssp. pekinensis). |
PubMed:Pre-harvest methyl jasmonate treatment enhances cauliflower chemoprotective attributes without a loss in postharvest quality. |
PubMed:Virtual screening for oseltamivir-resistant a (H5N1) influenza neuraminidase from traditional Chinese medicine database: a combined molecular docking with molecular dynamics approach. |
PubMed:BZR1 and BES1 participate in regulation of glucosinolate biosynthesis by brassinosteroids in Arabidopsis. |
PubMed:Glucosinolate biosynthesis in hairy root cultures of broccoli (Brassica oleracea var. italica). |
PubMed:Arabidopsis wat1 (walls are thin1)-mediated resistance to the bacterial vascular pathogen, Ralstonia solanacearum, is accompanied by cross-regulation of salicylic acid and tryptophan metabolism. |
PubMed:Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS. |
PubMed:Feasibility study on the use of visible-near-infrared spectroscopy for the screening of individual and total glucosinolate contents in broccoli. |
PubMed:Effects of various heating methods on glucosinolate, carotenoid and tocopherol concentrations in broccoli. |
PubMed:Health benefits and possible risks of broccoli - an overview. |
PubMed:Identification of glucosinolate congeners able to form DNA adducts and to induce mutations upon activation by myrosinase. |
PubMed:Tri-trophic effects of inter- and intra-population variation in defence chemistry of wild cabbage (Brassica oleracea). |
PubMed:Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products. |
PubMed:1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation. |
PubMed:Glucosinolates profile of "mugnolo", a variety of Brassica oleracea L. native to southern Italy (Salento). |
PubMed:Metabolic changes of Brassica rapa transformed with a bacterial isochorismate synthase gene. |
PubMed:Genetic variation in defense chemistry in wild cabbages affects herbivores and their endoparasitoids. |
PubMed:Metabolic engineering of indole glucosinolates in Chinese cabbage plants by expression of Arabidopsis CYP79B2, CYP79B3, and CYP83B1. |
PubMed:Changes of glucosinolates in mixed fresh-cut broccoli and cauliflower florets in modified atmosphere packaging. |
PubMed:Glucosinolates in Diplotaxis and Eruca leaves: diversity, taxonomic relations and applied aspects. |
PubMed:Development of an insect herbivore and its pupal parasitoid reflect differences in direct plant defense. |
PubMed:Correlation of glucosinolate content to myrosinase activity in horseradish (Armoracia rusticana). |
PubMed:Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure. |
PubMed:Health-promoting compounds in broccoli as influenced by refrigerated transport and retail sale period. |
PubMed:Flavor-active compounds potentially implicated in cooked cauliflower acceptance. |
PubMed:Biochemical effects of dietary intake of different broccoli samples. II. Multivariate analysis of contributions of specific glucosinolates in modulating cytochrome P-450 and antioxidant defense enzyme activities. |
PubMed:Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon. |
PubMed:The myrosinase-glucosinolate system in the interaction between Leptosphaeria maculans and Brassica napus. |
PubMed:The role of spatial scale and intraspecific variation in secondary chemistry in host-plant location by Ceutorhynchus assimilis (Coleoptera: Curculionidae). |
PubMed:Modulation of cytochrome P-450 and glutathione S-transferase isoform expression in vivo by intact and degraded indolyl glucosinolates. |
PubMed:An indole derivative and glucosinolates from Moricandia arvensis. |
PubMed:Distribution and Variation of Indole Glucosinolates in Woad (Isatis tinctoria L.). |
PubMed:Indole Compounds Related to Auxins and Goitrogens of Woad (Isatis tinctoria L.). |
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