EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

bilobetin

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CAS Number: 521-32-4Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J92.484I
XlogP3-AA:5.40 (est)
Molecular Weight:552.49240000
Formula:C31 H20 O10
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.008998 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Bilobetin 98%
BOC Sciences
For experimental / research use only.
Bilobetin >98%
Odor: characteristic
Use: Bilobetin is a natural flavonoid found in the leaves of Ginkgo biloba L, by stimulating PPARa-mediated lipid catabolism, bilobetin can treat ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats.
Carbosynth
For experimental / research use only.
Bilobetin
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for bilobetin usage levels up to:
 not for fragrance use.
 
Recommendation for bilobetin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5315459
National Institute of Allergy and Infectious Diseases:Data
8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Chemidplus:0000521324
 
References:
 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5315459
Pubchem (cas):521-32-4
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB30833
FooDB:FDB002789
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ginkgo biloba
Search Trop Picture
 
Synonyms:
3''',8-biflavone, 4',5,5'',7,7''-pentahydroxy-4'''-methoxy-
8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
4'-monomethylamentoflavone
 

Articles:

PubMed:[Chemical constituents from leaves of Garcinia xanthochymus].
PubMed:Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method.
PubMed:Virtual screening of natural inhibitors to the predicted HBx protein structure of Hepatitis B Virus using molecular docking for identification of potential lead molecules for liver cancer.
PubMed:UPLC-PDA-TOF/MS coupled with multivariate statistical analysis to rapidly analyze and evaluate Ginkgo biloba leaves from different origin.
PubMed:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARĪ± in rats fed a high-fat diet.
PubMed:Antiviral activity-guided fractionation from Araucaria angustifolia leaves extract.
PubMed:How to realize the linear scale-up process for rapid purification using high-performance counter-current chromatography.
PubMed:In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
PubMed:Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana.
PubMed:Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba.
PubMed:Biflavones from Chamaecyparis obtusa.
PubMed:Flavonoids from Metasequoia glyptostroboides.
PubMed:Constituents of antibacterial extract of Caesalpinia paraguariensis Burk.
PubMed:Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.
PubMed:Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes.
PubMed:Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide-induced nitric oxide production from the mouse macrophage cell line RAW 264.7.
PubMed:The effects of two new antagonists of secretory PLA2 on TNF, iNOS, and COX-2 expression in activated macrophages.
PubMed:Inhibition of cAMP-phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue.
PubMed:[HPLC determination of six flavonoid constituents in Ginkgo biloba leaves].
PubMed:Cytotoxic biflavonoids from Selaginella willdenowii.
PubMed:Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring biflavonoids.
PubMed:Effects of some compounds isolated fromCelaenodendron mexicanum standl (euphorbiaceae) on seeds and phytopathogenic fungi.
PubMed:Seasonal Variations of the Flavonoid Content from Ginkgo biloba Leaves.
PubMed:HPLC Separation and Quantitative Determination of Biflavones in Leaves from Ginkgo biloba.
 
Notes:
None found
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