EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

euxanthone
1,7-dihydroxyxanthone

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CAS Number: 529-61-3Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J6.687G
XlogP3-AA:2.80 (est)
Molecular Weight:228.20356000
Formula:C13 H8 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 6.882 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Euxanthone >95%
Odor: characteristic
Use: Euxanthone is a natural xanthone found in the roots of Polygala tenuifolia Willd, it can induce its vasodilator effect through inhibition of calcium-sensitive mechanisms activated by protein kinase C.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for euxanthone usage levels up to:
 not for fragrance use.
 
Recommendation for euxanthone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281631
National Institute of Allergy and Infectious Diseases:Data
1,7-dihydroxyxanthen-9-one
Chemidplus:0000529613
 
References:
 1,7-dihydroxyxanthen-9-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281631
Pubchem (cas):529-61-3
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C10061
HMDB (The Human Metabolome Database):HMDB30724
FooDB:FDB002648
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 mammea americana
Search Trop Picture
 mangifera indica
Search Trop Picture
 platonia insignis
Search Trop Picture
 
Synonyms:
1,7-dihydroxyxanthen-9-one
1,7-dihydroxyxanthone
9H-xanthen-9-one, 1,7-dihydroxy-
 

Articles:

PubMed:Identification of Lead Molecules in Garcinia mangostana L. Against Pancreatic Cholesterol Esterase Activity: An In Silico Approach.
PubMed:Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells.
PubMed:Antioxidative compounds from Garcinia buchananii stem bark.
PubMed:Chitosan enhances xanthone production in Hypericum perforatum subsp. angustifolium cell cultures.
PubMed:Mechanism of the vasodilator effect of Euxanthone in rat small mesenteric arteries.
PubMed:Analysis of the action of euxanthone, a plant-derived compound that stimulates neurite outgrowth.
PubMed:[Isolation and structure identification of chemical constituents from Polygala hongkongensis II].
PubMed:Anti-HIV-1 constituents from leaves and twigs of Cratoxylum arborescens.
PubMed:Cytotoxic activities of chemical constituents from Mesua daphnifolia.
PubMed:Vasorelaxant effect of euxanthone in the rat thoracic aorta.
PubMed:Involvement of protein kinase C and E2F-5 in euxanthone-induced neurite differentiation of neuroblastoma.
PubMed:Xanthones from the roots of Polygala caudata and their antioxidation and vasodilatation activities in vitro.
PubMed:Identification of signal transduction pathways that modulate dibutyryl cyclic adenosine monophosphate activation of stanniocalcin gene expression in neuroblastoma cells.
PubMed:Differential activation of protein kinase C isoforms by euxanthone, revealed by an in vivo yeast phenotypic assay.
PubMed:Effects of dibutyryl cAMP on stanniocalcin and stanniocalcin-related protein mRNA expression in neuroblastoma cells.
PubMed:Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells.
PubMed:Effects of euxanthone on neuronal differentiation.
 
Notes:
None found
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