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thiotaurine
ethanesulfonothioic acid, 2-amino-

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Name:	2-hydroxysulfonothioylethanamine
CAS Number:	2937-54-4	3D/inchi
ECHA EINECS - REACH Pre-Reg:	220-918-7
FDA UNII:	NQZ2D7AO62
Nikkaji Web:	J306.861G
XlogP3:	-0.10 (est)
Molecular Weight:	141.21319000
Formula:	C2 H7 N O2 S2
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:antioxidants

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 1e+006 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	antioxidants

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
antioxidants
Recommendation for thiotaurine usage levels up to:
	not for fragrance use.

Recommendation for thiotaurine flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6858023

National Institute of Allergy and Infectious Diseases:Data

2-hydroxysulfonothioylethanamine

Chemidplus:0002937544

References:

	2-hydroxysulfonothioylethanamine
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6858023
Pubchem (sid):	135034626

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

2-	aminoethanethiosulfonic acid
	ethanesulfonothioic acid, 2-amino-
2-	hydroxysulfonothioylethanamine

Articles:

PubMed:A Proteomic Approach to Study the Effect of Thiotaurine on Human Neutrophil Activation.

PubMed:Thiotaurine protects mouse cerebellar granule neurons from potassium deprivation-induced apoptosis by inhibiting the activation of caspase-3.

PubMed:Thiotaurine modulates human neutrophil activation.

PubMed:Comparative evaluation of taurine and thiotaurine as protectants against diabetes-induced nephropathy in a rat model.

PubMed:The effects of taurine and thiotaurine on oxidative stress in the aorta and heart of diabetic rats.

PubMed:Protection by taurine and thiotaurine against biochemical and cellular alterations induced by diabetes in a rat model.

PubMed:Thiotaurine prevents apoptosis of human neutrophils: a putative role in inflammation.

PubMed:Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat.

PubMed:Comparison of brain mitochondrial cytochrome c oxidase activity with cyanide LD(50) yields insight into the efficacy of prophylactics.

PubMed:Thiotaurine and hypotaurine contents in hydrothermal-vent polychaetes without thiotrophic endosymbionts: correlation With sulfide exposure.

PubMed:Hypotaurine and sulfhydryl-containing antioxidants reduce H2S toxicity in erythrocytes from a marine invertebrate.

PubMed:Oxidative effects of cigarette smoke on the human skin.

PubMed:Possible role of a taurine transporter in the deep-sea mussel Bathymodiolus septemdierum in adaptation to hydrothermal vents.

PubMed:High contents of hypotaurine and thiotaurine in hydrothermal-vent gastropods without thiotrophic endosymbionts.

PubMed:Development of an LC-MS-MS method for the quantification of taurine derivatives in marine invertebrates.

PubMed:Possible roles of sulfur-containing amino acids in a chemoautotrophic bacterium-mollusc symbiosis.

PubMed:Stimulatory effect of sulphide on thiotaurine synthesis in three hydrothermal-vent species from the East Pacific Rise.

PubMed:Unusual organic osmolytes in deep-sea animals: adaptations to hydrostatic pressure and other perturbants.

PubMed:In vitro effects of anionic sulfur compounds on the spectrophotometric properties of native DNA.

PubMed:High amounts of sulphur-amino acids in three symbiotic mytilid bivalves from deep benthic communities.

PubMed:Displacement of [(3)H]GABA binding to bovine brain receptors by sulfur-containing analogues.

PubMed:[Enzymatic systems evolved in the conversion of cystamine to thiotaurine and hypotaurine].

PubMed:Sulfur exchange between thiotaurine and hypotaurine.

PubMed:The enzymic conversion of cystamine and thiocysteamine into thiotaurine and hypotaurine.

PubMed:[Enzymatic conversion of cystamine into thiotaurine].

PubMed:Inability of thiotaurine to protect mice against ionizing radiation.

PubMed:Degradation of thiotaurine by ionizing radiations.

PubMed:Chromatographic evidence on the occurrence of thiotaurine in the urine of rats fed with cystine.

PubMed:On the synthesis and biochemistry of thiotaurine (amino-2-ethanethiosulfonic acid).

PubMed:[On the synthesis of thiotaurine].

Notes:

None found

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