thiohistidine, 2002-22-4

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CODE180179 CODE180179
Product(s):
2002-22-4 H-2-Mercapto-His-OH 99%
An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues

Name:	(2S)-2-amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid
CAS Number:	2002-22-4	3D/inchi
ECHA EINECS - REACH Pre-Reg:	217-899-2
FDA UNII:	MH6EDB26P8
Nikkaji Web:	J9.542G
XlogP3:	-3.60 (est)
Molecular Weight:	187.22213000
Formula:	C6 H9 N3 O2 S
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:antioxidant, bleaching agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 5.314e+004 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	antioxidants bleaching agents chelating agents

Suppliers:

BOC Sciences

For experimental / research use only.

H-2-Mercapto-His-OH 99%

Odor: characteristic

Use: An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
antioxidant, bleaching agents
Recommendation for thiohistidine usage levels up to:
	not for fragrance use.

Recommendation for thiohistidine flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :2733604

National Institute of Allergy and Infectious Diseases:Data

(2S)-2-amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid

Chemidplus:0002002224

References:

	(2S)-2-amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	2733604
Pubchem (sid):	135256076

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

(S)-alpha-	amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid
(2S)-2-	amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid
1H-	imidazole-4-propanoic acid,a-amino-2,3-dihydro-2-thioxo; (S)-a-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid
L-	thiolhistidine

Articles:

PubMed:Convergent evolution of ergothioneine biosynthesis in Cyanobacteria.

PubMed:Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis.

PubMed:Thiohistidine biosynthesis.

PubMed:Ovothiol: a novel thiohistidine compound from sea urchin eggs that confers NAD(P)H-O2 oxidoreductase activity on ovoperoxidase.

PubMed:L-Histidine ammonia-lyase activity of axenically grown Hartmannella culbertsoni.

Notes:

None found

thiohistidine 1H-imidazole-4-propanoic acid,a-amino-2,3-dihydro-2-thioxo; (S)-a-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid

Supplier Sponsors

Articles:

thiohistidine
1H-imidazole-4-propanoic acid,a-amino-2,3-dihydro-2-thioxo; (S)-a-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid