EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

rubusoside
kaur-16-en-18-oic acid, 13-(beta-D-glucopyranosyloxy)-, beta-D- glucopyranosyl ester, (4alpha)-

Supplier Sponsors

CAS Number: 64849-39-4Picture of molecule3D/inchi
FDA UNII: TCV5K3M3GX
Nikkaji Web:J292.224J
MDL:MFCD06799426
XlogP3-AA:0.40 (est)
Molecular Weight:642.74010000
Formula:C32 H50 O13
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:humectants, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 101.2 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: humectants
skin conditioning
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Rubusoside 98%
BOC Sciences
For experimental / research use only.
Rubusoside >98%
Odor: characteristic
Use: Rubusoside (R) is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties. It is useful for the food additive and pharmaceutical industries. Antiangiogenic/antiallergic
Layn Natural ingredients
Sweet Blackberry Leaf Rubusoside
Santa Cruz Biotechnology
For experimental / research use only.
Rubusoside
Sigma-Aldrich
For experimental / research use only.
Rubusoside analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
humectants, skin conditioning
Recommendation for rubusoside usage levels up to:
 not for fragrance use.
 
Recommendation for rubusoside flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24721373
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0064849394
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):24721373
Pubchem (sid):135080379
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 kaur-16-en-18-oic acid, 13-(beta-D-glucopyranosyloxy)-, beta-D- glucopyranosyl ester, (4alpha)-
 

Articles:

PubMed:A Novel Solubility-Enhanced Rubusoside-Based Micelles for Increased Cancer Therapy.
PubMed:Development and Validation of an Enzymatic Method To Determine Stevioside Content from Stevia rebaudiana.
PubMed:Employing rubusoside to improve the solubility and permeability of antitumor compound betulonic acid.
PubMed:Gene transcription and steviol glycoside accumulation in Stevia rebaudiana under polyethylene glycol-induced drought stress in greenhouse cultivation.
PubMed:Cariogenicity features of Streptococcus mutans in presence of rubusoside.
PubMed:Glucosyl Rubusosides by Dextransucrases Improve the Quality of Taste and Sweetness.
PubMed:Inhibition of human GLUT1 and GLUT5 by plant carbohydrate products; insights into transport specificity.
PubMed:Selective production of rubusoside from stevioside by using the sophorose activity of β-glucosidase from Streptomyces sp. GXT6.
PubMed:Degradation products of rubusoside under acidic conditions.
PubMed:Cytotoxic and antiangiogenic paclitaxel solubilized and permeation-enhanced by natural product nanoparticles.
PubMed:Production of rubusoside from stevioside by using a thermostable lactase from Thermus thermophilus and solubility enhancement of liquiritin and teniposide.
PubMed:Quantitation of sweet steviol glycosides by means of a HILIC-MS/MS-SIDA approach.
PubMed:The effect of curcumin on breast cancer cells.
PubMed:Characterization of a novel steviol-producing β-glucosidase from Penicillium decumbens and optimal production of the steviol.
PubMed:Synthesis and sensory evaluation of ent-kaurane diterpene glycosides.
PubMed:Reformulation of etoposide with solubility-enhancing rubusoside.
PubMed:Large-scale profiling of diterpenoid glycosides from Stevia rebaudiana using ultrahigh performance liquid chromatography/tandem mass spectrometry.
PubMed:Mass production of rubusoside using a novel stevioside-specific β-glucosidase from Aspergillus aculeatus.
PubMed:Structures of the novel α-glucosyl linked diterpene glycosides from Stevia rebaudiana.
PubMed:Diterpene glycosides from Stevia rebaudiana.
PubMed:Structures of the novel diterpene glycosides from Stevia rebaudiana.
PubMed:[Identification and biotransformation properties of a bacterium that converts stevioside into rubusoside].
PubMed:A new diterpene glycoside from Stevia rebaudiana.
PubMed:Paclitaxel-induced apoptosis is blocked by camptothecin in human breast and pancreatic cancer cells.
PubMed:A novel solubility-enhanced curcumin formulation showing stability and maintenance of anticancer activity.
PubMed:Improvement of obesity phenotype by Chinese sweet leaf tea (Rubus suavissimus) components in high-fat diet-induced obese rats.
PubMed:Purification of a water extract of Chinese sweet tea plant (Rubus suavissimus S. Lee) by alcohol precipitation.
PubMed:[Study on quality control of Rubus suavissimus].
PubMed:Quantitative and fingerprint analyses of Chinese sweet tea plant ( Rubus suavissimus S. Lee).
PubMed:Analysis of rubusoside and related compounds in tenryocha extract sweetener.
PubMed:Purification and some properties of a beta-glucosidase from Flavobacterium johnsonae.
PubMed:Solubilization of steviolbioside and steviolmonoside with gamma-cyclodextrin and its application to selective syntheses of better sweet glycosides from stevioside and rubusoside.
PubMed:Further study on the 1,4-alpha-transglucosylation of rubusoside, a sweet steviol-bisglucoside from Rubus suavissimus.
PubMed:Glucosylation of Steviol and Steviol-Glucosides in Extracts from Stevia rebaudiana Bertoni.
PubMed:Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside A, and rubusoside.
 
Notes:
None found
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