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alternariol
6H-dibenzo(b,d)pyran-6-one, 1-methyl-3,7,9-trihydroxy-

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Name:3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one
CAS Number: 641-38-3Picture of molecule3D/inchi
FDA UNII: KN9L4260JW
Nikkaji Web:J12.511C
Beilstein Number:0244839
MDL:MFCD00133068
XlogP3-AA:2.90 (est)
Molecular Weight:258.22970000
Formula:C14 H10 O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:toxic natural substances
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 61.89 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Alternariol
Sigma-Aldrich: Sigma
For experimental / research use only.
Alternariol from Alternaria sp. ∼96%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LDLo 100 mg/kg
EHP, Environmental Health Perspectives. Vol. 4, Pg. 87, 1973.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
toxic natural substances
Recommendation for alternariol usage levels up to:
 not for fragrance use.
 
Recommendation for alternariol flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Combined toxicokinetic and in vivo genotoxicity study on Alternaria toxins
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5359485
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one
Chemidplus:0000641383
RTECS:HP8757000 for cas# 641-38-3
 
References:
 3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5359485
Pubchem (sid):134976044
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C16838
HMDB (The Human Metabolome Database):HMDB30831
FooDB:FDB002787
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 alternaria tenuis
Search Trop Picture
 
Synonyms:
 AOH
6H-dibenzo(b,d)pyran-6-one, 1-methyl-3,7,9-trihydroxy-
3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one
3,4,4'-trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone
 

Articles:

PubMed:Using SILAC proteomics to investigate the effect of the mycotoxin, alternariol, in the human H295R steroidogenesis model.
PubMed:Quantitation of multiple mycotoxins and cyanogenic glucosides in cassava samples from Tanzania and Rwanda by an LC-MS/MS-based multi-toxin method.
PubMed:Distortion from planarity in arenes produced by internal rotation of one single hydroxyl hydrogen: the case of alternariol.
PubMed:Mycotoxigenic potential of fungi isolated from freshly harvested Argentinean blueberries.
PubMed:Oxidative stress of alternariol in Caco-2 cells.
PubMed:Water activity and temperature effects on growth of Alternaria arborescens on tomato medium.
PubMed:Bioactive secondary metabolites from Phomopsis sp., an endophytic fungus from Senna spectabilis.
PubMed:A new naphthalene glycoside from the sponge-derived fungus Arthrinium sp. ZSDS1-F3.
PubMed:Role of the Alternaria alternata blue-light receptor LreA (white-collar 1) in spore formation and secondary metabolism.
PubMed:Capsaicin production by Alternaria alternata, an endophytic fungus from Capsicum annum; LC-ESI-MS/MS analysis.
PubMed:Toxigenic profile and AFLP variability of Alternaria alternata and Alternaria infectoria occurring on wheat.
PubMed:The fungal phytotoxin alternariol 9-methyl ether and some of its synthetic analogues inhibit the photosynthetic electron transport chain.
PubMed:Faces of a changing climate: semi-quantitative multi-mycotoxin analysis of grain grown in exceptional climatic conditions in Norway.
PubMed:[Determination of the profiles of secondary metabolites characteristic of Alternaria strains isolated from tomato].
PubMed:[A new sesquiterpenoid from fungus Colletotrichum sp. and its cytotoxicity].
PubMed:Chemical constituents from the rice fermented with the edible mushroom Pleurotus eryngii and their quinone oxidoreductase 1 inducing effect.
PubMed:Mycotoxins: occurrence, toxicology, and exposure assessment.
PubMed:Alternariol 9-O-methyl ether dimethyl sulfoxide monosolvate.
PubMed:Secondary metabolites from Penicillium pinophilum SD-272, a marine sediment-derived fungus.
PubMed:Mycotoxins in corn and wheat silage in Israel.
PubMed:The necrotrophic effector SnToxA induces the synthesis of a novel phytoalexin in wheat.
PubMed:Mycoflora and mycotoxin contamination of Roundup Ready soybean harvested in the Pampean Region, Argentina.
PubMed:Dissecting the role of G-protein signalling in primary metabolism in the wheat pathogen Stagonospora nodorum.
PubMed:An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol.
PubMed:Natural occurrence of alternariol and alternariol monomethyl ether in soya beans.
PubMed:A new method for detection of five alternaria toxins in food matrices based on LC-APCI-MS.
PubMed:Conformational analysis of alternariol on the quantum level.
PubMed:Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages.
PubMed:Identification of Alternaria alternata mycotoxins by LC-SPE-NMR and their cytotoxic effects to soybean (Glycine max) cell suspension culture.
PubMed:Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina.
PubMed:The protective effect of hulls on the occurrence of Alternaria mycotoxins in spelt wheat.
PubMed:Modulation of the cellular redox status by the Alternaria toxins alternariol and alternariol monomethyl ether.
PubMed:Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada.
PubMed:Characterization of a genotoxic impact compound in Alternaria alternata infested rice as Altertoxin II.
PubMed:Mechanisms involved in alternariol-induced cell cycle arrest.
PubMed:Benzopyranones from the endophytic fungus Hyalodendriella sp. Ponipodef12 and their bioactivities.
PubMed:Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L.
PubMed:Minor contribution of alternariol, alternariol monomethyl ether and tenuazonic acid to the genotoxic properties of extracts from Alternaria alternata infested rice.
PubMed:Alternaria toxins: Altertoxin II is a much stronger mutagen and DNA strand breaking mycotoxin than alternariol and its methyl ether in cultured mammalian cells.
PubMed:Quantitation of mycotoxins in food and feed from Burkina Faso and Mozambique using a modern LC-MS/MS multitoxin method.
PubMed:Identification of a polyketide synthase required for alternariol (AOH) and alternariol-9-methyl ether (AME) formation in Alternaria alternata.
PubMed:A Dutch field survey on fungal infection and mycotoxin concentrations in maize.
PubMed:HOG MAP kinase regulation of alternariol biosynthesis in Alternaria alternata is important for substrate colonization.
PubMed:Heptaketides with antiviral activity from three endolichenic fungal strains Nigrospora sp., Alternaria sp. and Phialophora sp.
PubMed:Influence of pH and carbon to nitrogen ratio on mycotoxin production by Alternaria alternata in submerged cultivation.
PubMed:Alternariol 9-O-methyl ether.
PubMed:[Enzyme immunoassay of the secondary metabolites of micromycetes as components of lichen substances].
PubMed:Cell death induced by the Alternaria mycotoxin Alternariol.
PubMed:Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans.
PubMed:Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway.
PubMed:Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375.
PubMed:Chemical and molecular characterization of Phomopsis and Cytospora-like endophytes from different host plants in Brazil.
PubMed:Toxigenic Alternaria species from Argentinean blueberries.
PubMed:Mouse hepatoma cell lines differing in aryl hydrocarbon receptor-mediated signaling have different activities for glucuronidation.
PubMed:The Alternaria mycotoxins alternariol and alternariol methyl ether induce cytochrome P450 1A1 and apoptosis in murine hepatoma cells dependent on the aryl hydrocarbon receptor.
PubMed:Deoxynivalenol, deoxynivalenol-3-glucoside, and enniatins: the major mycotoxins found in cereal-based products on the Czech market.
PubMed:Determination of six Alternaria toxins with UPLC-MS/MS and their occurrence in tomatoes and tomato products from the Swiss market.
PubMed:Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells.
PubMed:Process development for the elucidation of mycotoxin formation in Alternaria alternata.
PubMed:Influence of water activity and temperature on growth and mycotoxin production by Alternaria alternata on irradiated soya beans.
PubMed:Tracing fungi secondary metabolites in Brazil nuts using LC-MS/MS.
PubMed:Widespread occurrence of low levels of alternariol in apple and tomato products, as determined by comparative immunochemical assessment using monoclonal and polyclonal antibodies.
PubMed:The influence of different nitrogen and carbon sources on mycotoxin production in Alternaria alternata.
PubMed:[Enzyme immunassay of alternariol for the assessment of risk of agricultural products contamination].
PubMed:[Simultaneous determination of four Alternaria toxins in apple juice concentrate by ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry].
PubMed:Oxidative metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in precision-cut rat liver slices in vitro.
PubMed:AFLP variability, toxin production, and pathogenicity of Alternaria species from Argentinean tomato fruits and puree.
PubMed:Precise determination of the Alternaria mycotoxins alternariol and alternariol monomethyl ether in cereal, fruit and vegetable products using stable isotope dilution assays.
PubMed:Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1.
PubMed:Analysis of multiple mycotoxins in cereals under ambient conditions using direct analysis in real time (DART) ionization coupled to high resolution mass spectrometry.
PubMed:Production and migration of mycotoxins in sweet pepper analyzed by Multimycotoxin LC-MS/MS.
PubMed:Water activity and temperature effects on mycotoxin production by Alternaria alternata on a synthetic tomato medium.
PubMed:Degradation of the Alternaria mycotoxins alternariol, alternariol monomethyl ether, and altenuene upon bread baking.
PubMed:The transcription factor StuA regulates central carbon metabolism, mycotoxin production, and effector gene expression in the wheat pathogen Stagonospora nodorum.
PubMed:Multi-mycotoxin analysis of maize silage by LC-MS/MS.
PubMed:Impact of water activity and temperature on growth and alternariol and alternariol monomethyl ether production of Alternaria alternata isolated from soybean.
PubMed:Alternariol.
PubMed:Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method.
PubMed:Cytotoxic metabolites produced by Alternaria no.28, an endophytic fungus isolated from Ginkgo biloba.
PubMed:Effects of gamma radiation on the growth of Alternaria alternata and on the production of alternariol and alternariol monomethyl ether in sunflower seeds.
PubMed:Absorption and metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in Caco-2 cells in vitro.
PubMed:LC-MS/MS multi-analyte method for mycotoxin determination in food supplements.
PubMed:New antitumour fungal metabolites from Alternaria porri.
PubMed:Stable isotope dilution assays of alternariol and alternariol monomethyl ether in beverages.
PubMed:The mycotoxins alternariol and alternariol methyl ether negatively affect progesterone synthesis in porcine granulosa cells in vitro.
PubMed:[Acute cytotoxicity of alternariol on NIH/3T3 cells].
PubMed:Glucuronidation of the mycotoxins alternariol and alternariol-9-methyl ether in vitro: chemical structures of glucuronides and activities of human UDP-glucuronosyltransferase isoforms.
PubMed:Mycoflora and mycotoxin production in oilseed cakes during farm storage.
PubMed:Development of a multi-mycotoxin liquid chromatography/tandem mass spectrometry method for sweet pepper analysis.
PubMed:Influence of alternariol (AOH) on regulator proteins of cap-dependent translation in porcine endometrial cells.
PubMed:Activities of human recombinant cytochrome P450 isoforms and human hepatic microsomes for the hydroxylation ofAlternaria toxins.
PubMed:Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform.
PubMed:Alternaria toxins in wheat during the 2004 to 2005 Argentinean harvest.
PubMed:Cytotoxic metabolites from the fungal endophyte Alternaria sp. and their subsequent detection in its host plant Polygonum senegalense.
PubMed:LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs.
PubMed:Mycotoxin production by Alternaria strains isolated from Argentinean wheat.
PubMed:Alternaria toxins: DNA strand-breaking activity in mammalian cellsin vitro.
PubMed:[Putative mycotoxin-producing fungi isolated from alpataco (Prosopis flexuosa) fruits].
PubMed:Analysis of alternariol and alternariol monomethyl ether on flavedo and albedo tissues of tangerines (Citrus reticulata) with symptoms of alternaria brown spot.
PubMed:Novel oxidative in vitro metabolites of the mycotoxins alternariol and alternariol methyl ether.
PubMed:Occurrence of alternariol, alternariol monomethyl ether and tenuazonic acid in Argentinean tomato puree.
PubMed:Real-time PCR quantification of the AM-toxin gene and HPLC qualification of toxigenic metabolites from Alternaria species from apples.
PubMed:Analysis of wines, grape juices and cranberry juices forAlternaria toxins.
PubMed:Further examination of the effects of nitrosylation on Alternaria alternata mycotoxin mutagenicity in vitro.
PubMed:Mutagenicity of the mycotoxin alternariol in cultured mammalian cells.
PubMed:Survey of the mycobiota of Spanish malting barley and evaluation of the mycotoxin producing potential of species of Alternaria, Aspergillus and Fusarium.
PubMed:Estrogenic and clastogenic potential of the mycotoxin alternariol in cultured mammalian cells.
PubMed:Toxigenic fungi isolated from dried vine fruits in Argentina.
PubMed:Toxigenic profile of Alternaria alternata and Alternaria radicina occurring on umbelliferous plants.
PubMed:Mycoflora and occurrence of alternariol and alternariol monomethyl ether in Brazilian sunflower from sowing to harvest.
PubMed:Total synthesis of alternariol.
PubMed:Occurrence ofAlternaria andFusarium mycotoxins in winter wheat from domestic crop in year 2003.
PubMed:Mycotoxin production byAlternaria strains isolated from tomatoes affected by Blackmold in Argentina.
PubMed:Liquid chromatographic determination of Alternaria toxins in carrots.
PubMed:Liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry of the Alternaria mycotoxins alternariol and alternariol monomethyl ether in fruit juices and beverages.
PubMed:6H-dibenzo[b,d]pyran-6-one derivatives from the cultured lichen mycobionts of Graphis spp. and their biosynthetic origin.
PubMed:Antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus Chaetomium globosum KMITL-N0802.
PubMed:Detection of Alternaria fungal contamination in cereal grains by a polymerase chain reaction-based assay.
PubMed:[In Process Citation].
PubMed:Analysis of agricultural commodities and foods for Alternaria mycotoxins.
PubMed:Analysis of toxic effects of Alternaria toxins on esophagus of mice by light and electron microscopy.
PubMed:Survey of Brazilian tomato products for alternariol, alternariol monomethyl ether, tenuazonic acid and cyclopiazonic acid.
PubMed:Examination of Alternaria alternata mutagenicity and effects of nitrosylation using the Ames Salmonella test.
PubMed:Mycotoxin-producing potential of fungi associated with qat (Catha edulis) leaves in Yemen.
PubMed:Production of alternaria mycotoxins by Alternaria alternata isolated from weather-damaged wheat.
PubMed:Production of alternariol and alternariol methyl ether by Alternaria alternata grown on fruits at various temperatures.
PubMed:Stability ofAlternaria toxins in fruit juices and wine.
PubMed:[Microbiological threat from buildings and rooms and its influence on human health (sick building syndrome)].
PubMed:Alternaria mycotoxins in weathered wheat from China.
PubMed:Mycotoxins from mould infested building materials.
PubMed:Production of mycotoxins on artificially and naturally infested building materials.
PubMed:Biological detoxification of fungal toxins and its use in plant breeding, feed and food production.
PubMed:Determination of alternariol in tomato paste using solid phase extraction and high-performance liquid chromatography with fluorescence detection.
PubMed:Effect of heat treatments on stability of altemariol, alternariol monomethyl ether and tenuazonic acid in sunflower flour.
PubMed:Natural occurrence of alternariol and alternariol methyl ether in Spanish apple juice concentrates.
PubMed:Production of alternariol and alternariol mono-methyl ether by isolates of Alternaria spp. from Argentinian maize.
PubMed:Mycotoxins of Alternaria alternata produced on ceiling tiles.
PubMed:Microbial interaction ofAspergillus parasiticus andBacillus subtilis withalternaria alternata. production of alternariol, alternariol monomethylether and tenuazonic acid on sunflower seeds.
PubMed:Mycotoxins in ingredients of animal feeding stuffs: I. Determination of Alternaria mycotoxins in oilseed rape meal and sunflower seed meal.
PubMed:Gas chromatography-mass spectrometry of Alternaria mycotoxins.
PubMed:Evaluation of Alternaria and its mycotoxins during ensiling of sunflower seeds.
PubMed:Determination of alternariol and alternariol methyl ether in apple juice using solid-phase extraction and high performance liquid chromatography.
PubMed:Effect of dichlorvos on growth and mycotoxin production by Alternaria alternata.
PubMed:The inhibitory effect of extracts from Fructus lycii and Rhizoma polygonati on in vitro DNA breakage by alternariol.
PubMed:Alternaria mycotoxins in black rot lesion of tomato fruit: conditions and regulation of their production.
PubMed:Effect of pesticides inAlternaria alternata mycotoxins production.
PubMed:An indirect enzyme immunoassay for the mycotoxin citrinin.
PubMed:[Determination of Alternaria mycotoxins in selected raw and processed fruit and vegetable products].
PubMed:Mycotoxin production by Alternaria alternata strains isolated from red delicious apples in Argentina.
PubMed:Inhibition of growth and mycotoxin production of Alternaria alternata inhabiting decayed fruits by pesticides.
PubMed:Evaluation of alternariol and alternariol methyl ether for mutagenic activity in Salmonella typhimurium.
PubMed:Production of alternarioi and alternariol monomethyl ether in natural substrates in comparison with semisynthetic culture medium.
PubMed:Mycotoxin production by some IndianAlternaria species.
PubMed:Etiological role of Alternaria alternata in human esophageal cancer.
PubMed:Alternaria alternata from oilseed rape: mycotoxin production, and toxicity toArtemia salina larvae and rape seedlings.
PubMed:Inhibition of polyketide synthesis in Alternaria alternata by the fatty acid synthesis inhibitor cerulenin.
PubMed:[Toxin-producing ability of molds of the genus Alternaria].
PubMed:[The detection of Alternaria mycotoxins in laboratory culture].
PubMed:Toxicity of mycotoxins produced by four Alternaria species toArtemia salina larvae.
PubMed:Regulation of mycotoxin biosynthesis inAlternaria.
PubMed:Biosynthesis and preparation of fiveAlternaria metabolites.
PubMed:[Studies on the activation of oncogenes by alternariol monomethyl ether in human fetal esophageal epithelium].
PubMed:Relationships between Alternaria alternata and oesophageal cancer.
PubMed:Mutagenicity of Alternaria alternata and Penicillium cyclopium isolated from grains in an area of high incidence of oesophageal cancer--Linxian, China.
PubMed:Toxin production by Alternaria alternata in tomatoes and apples stored under various conditions and quantitation of the toxins by high-performance liquid chromatography.
PubMed:Natural occurrence of Alternaria mycotoxins in sorghum and ragi from North Bihar, India.
PubMed:The effect of ADH and insulin on active sodium transport across frog skin in the presence of alternariol mycotoxin.
PubMed:Natural occurrence ofAlternaria mycotoxins in the grain and chaff of cereals.
PubMed:Profiling of Alternaria mycotoxins in foodstuffs by high-performance liquid chromatography with diode-array ultraviolet detection.
PubMed:Mycotoxin-producing potential of fungi isolated from red kidney beans.
PubMed:Nitrogen inhibition of mycotoxin production by Alternaria alternata.
PubMed:The effect of alternariol mycotoxin (AOH) on active sodium transport across frog skin (Rana esculenta).
PubMed:Metabolism of alternariol monomethyl ether by porcine liver and intestinal mucosa in vitro.
PubMed:Standardized high-performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indices and UV-VIS spectra (diode array detection).
PubMed:Natural occurrence of Alternaria mycotoxins in olives--their production and possible transfer into the oil.
PubMed:Alternariol, a dibenzopyrone mycotoxin of Alternaria spp., is a new photosensitizing and DNA cross-linking agent.
PubMed:Liquid chromatographic determination of tenuazonic acid and alternariol methyl ether in tomatoes and tomato products.
PubMed:Effect of water activity and temperature on mycotoxin production by Alternaria alternata in culture and on wheat grain.
PubMed:Toxicity of the Alternaria metabolites alternariol, alternariol methyl ether, altenuene, and tenuazonic acid in the chicken embryo assay.
PubMed:The subchronic toxicity and teratogenicity of alternariol monomethyl ether produced by Alternaria solani.
PubMed:The distribution, elimination, and metabolism of 14C-alternariol monomethyl ether.
PubMed:Mutagens produced by Alternaria alternata.
PubMed:Blue light inhibits mycotoxin production and increases total lipids and pigmentation in Alternaria alternata.
PubMed:Toxins of molds from decaying tomato fruit.
PubMed:Light inhibits the production of alternariol and alternariol monomethyl ether in Alternaria alternata.
PubMed:Some newly discovered mycotoxins.
PubMed:Effect of substrate on metabolite production of Alternaria alternata.
PubMed:Regulation and metabolic background of polyketide formation. I. Effects of (-)-hydroxycitrate and metabolic roles of citrate and malate in fatty acid and polyketide formations.
PubMed:Alternariol, a new fungal anticholinesterase drug. I.
PubMed:Analysis of tobacco for the Alternaria toxins, alternariol and alternariol monomethyl ether.
PubMed:Gas and thin-layer chromatographic methods for analysis of the mycotoxins altenuene, alternariol, and alternariol monomethyl ether.
PubMed:Studies on the enzyme synthesizing the aromatic product alternariol.
PubMed:Studies in the biosynthesis of fungal metabolites. 4. Alternariol monomethyl ether and its relation to other phenolic metabolites of Alternaria tenuis.
PubMed:Studies in the biosynthesis of fungal metabolites. 2. The biosynthesis of alternariol and its relation to other fungal phenols.
PubMed:Studies in the biochemistry of microorganisms. 90. Alternariol and alternariol monomethyl ether, metabolic products of Alternaria tenuis.
 
Notes:
Occurs in mycelium of Alternaria tenuis responsible for alternaria cone disorder in hops and fruit spot on papaya (Carica papaya) and Passiflora spp. Alternariol is a toxic metabolite of Alternaria fungi. It is an important contaminant in cereals and fruits.
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