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7-hydroxyflavanone
4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-phenyl-

Supplier Sponsors

Name:7-hydroxy-2-phenyl-2,3-dihydrochromen-4-one
CAS Number: 6515-36-2Picture of molecule3D/inchi
FDA UNII: CC64495H41
Nikkaji Web:J502.873F
MDL:MFCD00017487
XlogP3-AA:2.50 (est)
Molecular Weight:240.25824000
Formula:C15 H12 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 464.30 °C. @ 760.00 mm Hg (est)
Flash Point: 358.00 °F. TCC ( 181.20 °C. ) (est)
logP (o/w): 3.490 (est)
Soluble in:
 water, 416.5 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
ExtraSynthese
For experimental / research use only.
7-Hydroxyflavanone
Santa Cruz Biotechnology
For experimental / research use only.
7-Hydroxyflavanone
Sigma-Aldrich: Aldrich
For experimental / research use only.
7-Hydroxyflavanone 98%
sds
TCI AMERICA
For experimental / research use only.
7-Hydroxyflavanone >98.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for 7-hydroxyflavanone usage levels up to:
 not for fragrance use.
 
Recommendation for 7-hydroxyflavanone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1890
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
7-hydroxy-2-phenyl-2,3-dihydrochromen-4-one
Chemidplus:0006515362
 
References:
 7-hydroxy-2-phenyl-2,3-dihydrochromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):1890
Pubchem (sid):135117637
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C14290
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2932.99.7000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-phenyl-
7-hydroxy-2-phenyl-2,3-dihydrochromen-4-one
 

Articles:

PubMed:The effect of Zuccagnia punctata, an Argentine medicinal plant, on virulence factors from candida species.
PubMed:Molecular docking and 3D-QSAR-based virtual screening of flavonoids as potential aromatase inhibitors against estrogen-dependent breast cancer.
PubMed:Regiospecificity of human UDP-glucuronosyltransferase isoforms in chalcone and flavanone glucuronidation determined by metal complexation and tandem mass spectrometry.
PubMed:Effects of Zuccagnia punctata extracts and their flavonoids on the function and expression of ABCB1/P-glycoprotein multidrug transporter.
PubMed:Bioconversion of 7-hydroxyflavanone: isolation, characterization and bioactivity evaluation of twenty-one phase I and phase II microbial metabolites.
PubMed:Evaluation of novel amylose and cellulose-based chiral stationary phases for the stereoisomer separation of flavanones by means of nano-liquid chromatography.
PubMed:Microbial transformations of 7-hydroxyflavanone.
PubMed:Potentiality of standardized extract and isolated flavonoids from Zuccagnia punctata for the treatment of respiratory infections by Streptococcus pneumoniae: in vitro and in vivo studies.
PubMed:In vitro analysis of iron chelating activity of flavonoids.
PubMed:20S proteasome inhibitory activity of flavonoids isolated from Spatholobus suberectus.
PubMed:Comprehensive review of Clerodendrum phlomidis: a traditionally used bitter.
PubMed:Optical isomer separation of flavanones and flavanone glycosides by nano-liquid chromatography using a phenyl-carbamate-propyl-beta-cyclodextrin chiral stationary phase.
PubMed:Determination of seven flavonoids in Ixeridium gracile (DC.) Shih by high-performance liquid chromatography.
PubMed:Singlet oxygen quenching and radical scavenging capacities of structurally-related flavonoids present in Zuccagnia punctata Cav.
PubMed:Antimetastatic potentials of flavones on oral cancer cell via an inhibition of matrix-degrading proteases.
PubMed:Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.
PubMed:Epoxide formation on the aromatic B ring of flavanone by biphenyl dioxygenase of Pseudomonas pseudoalcaligenes KF707.
PubMed:Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.
PubMed:Phenolic constituents from Dalbergia cochinchinensis.
PubMed:Reaction mechanism of chalcone isomerase. pH dependence, diffusion control, and product binding differences.
PubMed:Phytonutrition, phytotherapy, and phytopharmacology.
PubMed:Actions of some flavonoids on specific and non-specific immune mechanisms.
PubMed:A chalcone glycoside from Clerodendron phlomidis.
PubMed:[Microbial kinetics: experiences with Staphylococcus aureus ATCC 25 293 and bacteriostatic drugs].
 
Notes:
None found
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