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palmatine chloride
dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, chloride

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Name:2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
CAS Number: 10605-02-4Picture of molecule3D/inchi
FDA UNII: ZJ6W8881Z8
MDL:MFCD00150276
Molecular Weight:387.86214000
Formula:C21 H22 Cl N O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 738.5 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Palmatine Chloride 98%
BOC Sciences
For experimental / research use only.
Palmatine hydrochloride >98%
Odor: characteristic
Use: Palmatine hydrochloride (Palmatine chloride (6CI,7CI)) is a hydrochloride salt of palmatine which is a protoberberine alkaloid, has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases.
ExtraSynthese
For experimental / research use only.
Palmatine chloride
Santa Cruz Biotechnology
For experimental / research use only.
Palmatine Chloride ≥97%
Sigma-Aldrich: Sigma
For experimental / research use only.
Palmatine Chloride ≥98% (HPLC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for palmatine chloride usage levels up to:
 not for fragrance use.
 
Recommendation for palmatine chloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :73442
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
Chemidplus:0010605024
 
References:
 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):73442
Pubchem (sid):135031117
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, chloride
2,3,9,10-tetramethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium chloride
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
 

Articles:

PubMed:Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents.
PubMed:Study on the phosphorescence characterizations of palmatine chloride on the solid substrate and its interaction with ctDNA.
PubMed:[Establishment of the control substance of plant drug and fingerprints of Coptis chinensis].
PubMed:Rat lens aldose reductase inhibitory activities of Coptis japonica root-derived isoquinoline alkaloids.
PubMed:Sheathless capillary electrophoresis/electrospray mass spectrometry using a carbon-coated tapered fused-silica capillary with a beveled edge.
PubMed:Antiphotooxidative activity of protoberberines derived from Coptis japonica makino in the chlorophyll-sensitized photooxidation of oil.
PubMed:Growth-inhibiting effects of Coptis japonica root-derived isoquinoline alkaloids on human intestinal bacteria.
PubMed:In-vitro evaluation of the antimicrobial activities of Enantia chlorantha Oliv. extractives.
 
Notes:
None found
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