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tebufenozide
benzoic acid, 3,5-dimethyl-, 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide

Supplier Sponsors

Name:N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
CAS Number: 112410-23-8Picture of molecule3D/inchi
FDA UNII: TNN5MI5EKF
Nikkaji Web:J540.289A
Beilstein Number:7822297
MDL:MFCD00467963
XlogP3:3.90 (est)
Molecular Weight:352.47756000
Formula:C22 H28 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 191.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:2.250000 mmHg @ 2.25 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 4.240 (est)
Soluble in:
 water, 0.83 mg/L @ 25 °C (exp)
 water, 1.405 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Tebufenozide 98%
Odor: characteristic
Use: Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidop
Santa Cruz Biotechnology
For experimental / research use only.
Tebufenozide ≥98%
Sigma-Aldrich
For experimental / research use only.
Tebufenozide PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for tebufenozide usage levels up to:
 not for fragrance use.
 
Recommendation for tebufenozide flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the modification of the existing MRLs for tebufenozide in various crops
View page or View pdf

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Review of the existing maximum residue levels for tebufenozide according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for tebufenozide in light of confirmatory data
View page or View pdf

Modification of the existing maximum residue levels for tebufenozide in apricots and peaches
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91773
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
Chemidplus:0112410238
 
References:
 N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):91773
Pubchem (sid):135047632
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18526
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•usepaopp pesticide code 129026; trade names: rh-5992 2f, rh-5992 technical. •wettable powder, suspension concentrate, ultra-low volume suspension, dispersible powder, granule •mimic (rohm & haas) •confirm 2f (23% tebufenozide) •confirm 70 wsp (70% tebufenozide) •mimic 2lv (24% tebufenozide) •tebufenozide technical (99% tebufenozide)
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 benzoic acid, 3,5-dimethyl-, 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide
N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
N'-(t-butyl)-N'-(3,5-dimethylbenzoyl)-N-(4-ethylbenzoyl)hydrazine
N'-(4-ethylbenzoyl)-3,5-dimethyl-N-(2-methyl-2-propanyl)benzohydrazide
 tebufenoxide
 RH-5992
 

Articles:

PubMed:Resistance in Cnaphalocrocis medinalis (Lepidoptera: Pyralidae) to new chemistry insecticides.
PubMed:A cell-based reporter assay for screening for EcR agonist/antagonist activity of natural ecdysteroids in Lepidoptera (Bm5) and Diptera (S2) cell cultures, followed by modeling of ecdysteroid-EcR interactions and normal mode analysis.
PubMed:Tebufenozide disrupts ovarian development and function in silkmoths.
PubMed:Insecticide resistance status of field populations of Spodoptera exigua (Lepidoptera: Noctuidae) from China.
PubMed:Comparative effects of insecticides with different mechanisms of action on Chrysoperla externa (Neuroptera: Chrysopidae): lethal, sublethal and dose-response effects.
PubMed:Assessment of pesticide residues in Karaboğaz Lake from Kızılırmak Delta, Turkey.
PubMed:Protein tyrosine phosphatase encoded in Cotesia plutellae bracovirus suppresses a larva-to-pupa metamorphosis of the diamondback moth, Plutella xylostella.
PubMed:Cloning and functional analysis of the ecdysteroid receptor complex in the opossum shrimp Neomysis integer (Leach, 1814).
PubMed:A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae.
PubMed:Low field-relevant tebufenozide concentrations affect reproduction in Chironomus riparius (Diptera: Chironomidae) in a long-term toxicity test.
PubMed:Acute toxicities and sublethal effects of some conventional insecticides on Trichogramma chilonis (Hymenoptera: Trichogrammatidae).
PubMed:Structural changes under low evolutionary constraint may decrease the affinity of dibenzoylhydrazine insecticides for the ecdysone receptor in non-lepidopteran insects.
PubMed:Selectivity of diacylhydrazine insecticides to the predatory bug Orius laevigatus: in vivo and modelling/docking experiments.
PubMed:Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach.
PubMed:Ecdysteroid receptor docking suggests that dibenzoylhydrazine-based insecticides are devoid of any deleterious effect on the parasitic wasp Psyttalia concolor (Hym. Braconidae).
PubMed:Assessment of toxicity risk of insecticides used in rice ecosystem on Trichogramma japonicum, an egg parasitoid of rice lepidopterans.
PubMed:Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry.
PubMed:Sequencing and structural homology modeling of the ecdysone receptor in two chrysopids used in biological control of pest insects.
PubMed:The use of the first order system transfer function in the analysis of proboscis extension learning of honey bees, Apis mellifera L., exposed to pesticides.
PubMed:Development of an in vitro binding assay for ecdysone receptor of mysid shrimp (Americamysis bahia).
PubMed:LC/MS/MS identification of 20-hydroxyecdysone in a scorpion (Liocheles australasiae) and its binding affinity to in vitro-translated molting hormone receptors.
PubMed:Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties.
PubMed:Residue analysis of four diacylhydrazine insecticides in fruits and vegetables by Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method using ultra-performance liquid chromatography coupled to tandem mass spectrometry.
PubMed:Single solid phase extraction method for the simultaneous analysis of polar and non-polar pesticides in urine samples by gas chromatography and ultra high pressure liquid chromatography coupled to tandem mass spectrometry.
PubMed:Regulatory mechanism of silkworm hemocyte adhesion to organs.
PubMed:Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.
PubMed:Insecticide susceptibility of Cnaphalocrocis medinalis (Lepidoptera: Pyralidae) in China.
PubMed:Tools for resistance monitoring in oriental fruit moth (Lepidoptera: Tortricidae) and first assessment in Brazilian populations.
PubMed:Fate of three insect growth regulators (IGR) insecticides (flufenoxuron, lufenuron and tebufenozide) in grapes following field application and through the wine-making process.
PubMed:Reducing the impact of pesticides on biological control in Australian vineyards: pesticide mortality and fecundity effects on an indicator species, the predatory mite Euseius victoriensis (Acari: Phytoseiidae).
PubMed:An epidermis-specific chitin synthase CDNA in Choristoneura fumiferana: cloning, characterization, developmental and hormonal-regulated expression.
PubMed:Potential of Metarhizium anisopliae (Metsch.) Sorokin (Ascomycetes, hypocreales) in the control of Bonagota salubricola (Meyrick) (Lepidoptera, Tortricidae) and its compatibility with chemical insecticides.
PubMed:[Determination of five diacylhydrazine insecticide residues in welsh onion using high performance liquid chromatography-tandem mass spectrometry].
PubMed:Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles.
PubMed:Activity of broad-spectrum and reduced-risk insecticides on various life stages of cranberry fruitworm (Lepidoptera: Pyralidae) in highbush blueberry.
PubMed:Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish.
PubMed:20-Hydroxyecdysone regulation of H-fibroin gene in the stored grain pest Corcyra cephalonica, during the last instar larval development.
PubMed:[Determination of benzoylurea and bishydrazide pesticide residues in vegetables by ultra performance liquid chromatography-tandem mass spectrometry with matrix solid phase dispersion].
PubMed:Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays.
PubMed:Simultaneous determination of phoxim and its photo-transformation metabolite residues in eggs using liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
PubMed:Changes of sex pheromone communication systems associated with tebufenozide and abamectin resistance in diamondback moth, Plutella xylostella (L.).
PubMed:Ecdysteroid-mediated expression of hexamerin (arylphorin) in the rice moth, Corcyra cephalonica.
PubMed:Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays.
PubMed:Two epsilon glutathione S-transferase cDNAs from the common cutworm, Spodoptera litura: characterization and developmental and induced expression by insecticides.
PubMed:Towards Coleoptera-specific high-throughput screening systems for compounds with ecdysone activity: development of EcR reporter assays using weevil (Anthonomus grandis)-derived cell lines and in silico analysis of ligand binding to A. grandis EcR ligand-binding pocket.
PubMed:Inheritance, fitness cost and mechanism of resistance to tebufenozide in Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae).
PubMed:Determination of 142 pesticides in fruit- and vegetable-based infant foods by liquid chromatography/electrospray ionization-tandem mass spectrometry and estimation of measurement uncertainty.
PubMed:Efficacy results of insecticides against Cydia pomonella, the codling moth, in Belgium during the last decade (1998-2007).
PubMed:Selection and life history traits of tebufenozide-resistant sugarcane borer (Lepidoptera: Crambidae).
PubMed:Effects of tebufenozide on ovarian growth and sexual behavior in the German cockroach (Blattella germanica).
PubMed:Cloning, characterization and expression of two glutathione S-transferase cDNAs in the spruce budworm, Choristoneura fumiferana.
PubMed:Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives.
PubMed:Effects of RH-5992 on ecdysteroidogenesis of the prothoracic glands during the fourth larval instar of the silkworm, Bombyx mori.
PubMed:Predicting economic losses from the continued spread of the Mexican rice borer (Lepidoptera: Crambidae).
PubMed:[Construction of a yeast model for screening Aedes albopictus ecdysone agonist pesticides].
PubMed:Joint action of quercetin with four insecticides on the cotton leaf-worm larvae, Spodoptera littoralis Boisd. (Lep. : Noctuidae) in Egypt.
PubMed:High throughput quantification of mutant huntingtin aggregates.
PubMed:Cloning, expression, and localization of a molt-related beta-N-acetylglucosaminidase in the spruce budworm, Choristoneura fumiferana.
PubMed:Quantitative structure-activity relationship of some pesticides.
PubMed:The ecological impact of four IGR insecticides in adults of Hyposoter didymator (Hym., Ichneumonidae): pharmacokinetics approach.
PubMed:Pesticide analysis in rose wines by micellar electrokinetic chromatography.
PubMed:Cloning and characterization of two glutathione S-transferase cDNAs in the spruce budworm, Choristoneura fumiferana.
PubMed:Multiple pesticide analysis in wine by MEKC combined with solid-phase microextraction and sample stacking.
PubMed:Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives.
PubMed:Synthesis and insecticidal evaluation of novel N'-tert-butyl-N'-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives.
PubMed:Diversity of insecticide resistance mechanisms and spectrum in European populations of the codling moth, Cydia pomonella.
PubMed:Prostaglandin signaling and ovarian follicle development in the silkmoth, Bombyx mori.
PubMed:Novel life stage targets against plum curculio, Conotrachelus nenuphar (Herbst), in apple integrated pest management.
PubMed:Diapause disruption with tebufenozide for early-instar control of the spruce budworm, Choristoneura fumiferana.
PubMed:Effects of tebufenozide on some aspects of lake trout (Salvelinus namaycush) immune response.
PubMed:Ovicidal and larvicidal effectiveness of insecticides applied by dipping apples on the small fruit tortrix Grapholita lobarzewskii.
PubMed:Agrichemical impact on growth and survival of non-target apple phyllosphere microorganisms.
PubMed:MEKC combined with SPE and sample stacking for multiple analysis of pesticides in water samples at the ng/L level.
PubMed:QSAR and mode of action studies of insecticidal ecdysone agonists.
PubMed:Pesticides in the Rhône river delta (France): basic data for a field-based exposure assessment.
PubMed:Sensory cell proliferation within the olfactory epithelium of developing adult Manduca sexta (Lepidoptera).
PubMed:Expression and down-regulation of cytochrome P450 genes of the CYP4 family by ecdysteroid agonists in Spodoptera littoralis and Drosophila melanogaster.
PubMed:Bumblebees can be used in combination with juvenile hormone analogues and ecdysone agonists.
PubMed:Sublethal effects of chronic exposure to tebufenozide on the development, survival, and reproduction of the tufted apple bud moth (Lepidoptera: Tortricidae).
PubMed:Potential of selective insecticides for managing Uraba lugens (Lepidoptera: Nolidae) on Eucalypts.
PubMed:Influence of fluctuating salinity on insecticide tolerance of two euryhaline arthropods.
PubMed:Tebufenozide resistance selected in Plutella xylostella and its cross-resistance and fitness cost.
PubMed:Comparative toxicity of three ecdysone agonist insecticides against the Mediterranean flour moth.
PubMed:Two lepidopteran cell lines stably transformed by the abc transporter gene pdr5 show tolerance to diacetoxyscirpenol.
PubMed:Evaluation of novel insecticides for control of dengue vector Aedes aegypti (Diptera: Culicidae).
PubMed:Mouthpart deformity and developmental retardation exposure of Chironomus plumosus (Diptera: Chironomidae) to tebufenozide.
PubMed:Nonsteroidal ecdysone agonists.
PubMed:Resistance and cross-resistance in populations of the leafrollers, Choristoneura rosaceana and Pandemis pyrusana , in Washington apples.
PubMed:The effects of four insect growth-regulating (IGR) insecticides on honeybee (Apis mellifera L.) colony development, queen rearing and drone sperm production.
PubMed:Two-dimensional gel electrophoresis analysis of proteins following tebufenozide treatment of Chironomus riparius.
PubMed:Effects of insect growth regulators on the nontarget soil arthropod Folsomia candida (Collembola).
PubMed:Reduced susceptibility to tebufenozide in populations of the sugarcane borer (Lepidoptera: Crambidae) in Louisiana.
PubMed:Comparative effects of a non-steroidal ecdysone agonist RH-5992 and 20-hydroxyecdysone in a lepidopteran cell line (IAL-PID2).
PubMed:Developmental expression patterns of four chemosensory protein genes from the Eastern spruce budworm, Chroistoneura fumiferana.
PubMed:Effect of a plant growth regulator prohexadione-calcium on insect pests of apple and pear.
PubMed:Stage-specific control of grape berry moth, Endopiza viteana (Clemens) (Lepidoptera: Tortricidae), by selective and broad-spectrum insecticides.
PubMed:Evaluation of biological and biorational control tactics for suppression of Nantucket pine tip moth damage in Virginia pine Christmas trees.
PubMed:Influence of the nonsteroidal ecdysone agonist, tebufenozide, on certain biological and physiological parameters of the cotton leaf-worm, Spodoptera littoralis (Boisd.) (Noctuidae: Lepidoptera) in Egypt.
PubMed:Action of 24-epibrassinolide on a cell line of the beet armyworm, Spodoptera exigua.
PubMed:[Investigation on extraction conditions of tebufenozide residue from cabbage using supercritical fluid extraction].
PubMed:Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells.
PubMed:Chemical residues and bioactivity of tebufenozide applied to apple foliage.
PubMed:Synthesis and insecticidal evaluation of novel N-oxalyl derivatives of tebufenozide.
PubMed:Comparative larvicidal toxicities of three ecdysone agonists on the mosquitoes Aedes aegypti, Culex quinquefasciatus, and Anopheles gambiae.
PubMed:Toxicity and residual activity of methoxyfenozide and tebufenozide to codling moth (Lepidoptera: Tortricidae) and oriental fruit moth (Lepidoptera: Tortricidae).
PubMed:Effects of propanil, tebufenozide and mefenacet on growth of four freshwater species of phytoplankton: a microplate bioassay.
PubMed:Effects of larval exposure to sublethal concentrations of the ecdysteroid agonists RH-5849 and tebufenozide (RH-5992) on male reproductive physiology in Spodoptera litura.
PubMed:Synergism of insecticides provides evidence of metabolic mechanisms of resistance in the obliquebanded leafroller Choristoneura rosaceana (Lepidoptera: Tortricidae).
PubMed:Comparative effects of some ecdysteroid agonists in mealworms: ecdysteroid amounts and protein analysis in developing ovaries under in vivo conditions.
PubMed:Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed:Some ecological implications of a neem (azadirachtin) insecticide disturbance to zooplankton communities in forest pond enclosures.
PubMed:Laboratory and field evaluation of tebufenozide, diflubenzuron, and Bacillus thurengiensis var. kurstaki for suppression of Douglas-fir tussock moth (Orgyia pseudotsugata (McDunnough)) in Idaho: a case study.
PubMed:An ecdysone-inducible putative "DEAD box" RNA helicase in the spruce budworm (Choristoneura fumiferana).
PubMed:Vineyard pesticides and their effects on invertebrate biomarkers and bioindicator species in New Zealand.
PubMed:Morphological and molecular effects of 20-hydroxyecdysone and its agonist tebufenozide on CF-203, a midgut-derived cell line from the spruce budworm, Choristoneura fumiferana.
PubMed:Ecdysone agonists: mechanism and importance in controlling insect pests of agriculture and forestry.
PubMed:The ecdysone regulatory cascade and ovarian development in lepidopteran insects: insights from the silkmoth paradigm.
PubMed:Toxicity and pharmacokinetics of insect growth regulators and other novel insecticides on pupae of Hyposoter didmator (Hymenoptera: Ichneumonidae), a parasitoid of early larval instars of lepidopteran pests.
PubMed:Effects of ecdysone agonists on the expression of EcR, USP and other specific proteins in the ovaries of the codling moth (Cydia pomonella L.).
PubMed:Sequential sampling and biorational chemistries for management of lepidopteran pests of vegetable amaranth in the Caribbean.
PubMed:Temporal, spatial and induced expression of chitinase in the spruce budworm, Choristoneura fumiferana.
PubMed:Binding mode of ecdysone agonists to the receptor: comparative modeling and docking studies.
PubMed:Effect of ecdysone agonists on vitellogenesis and the expression of EcR and USP in codling moth (Cydia pomonella).
PubMed:Synthesis and insecticidal activity of benzoheterocyclic analogues of N'-benzoyl-N-(tert-butyl)benzohydrazide: Part 1. Design of benzoheterocyclic analogues.
PubMed:Environmental chemicals with known endocrine potential affect yolk protein content in the aquatic insect Chironomus riparius.
PubMed:A molt-associated chitinase cDNA from the spruce budworm, Choristoneura fumiferana.
PubMed:Significance of penetration, excretion, and transovarial uptake to toxicity of three insect growth regulators in predatory lacewing adults.
PubMed:Resistance and cross-resistance to four insecticides in populations of obliquebanded leafroller (Lepidoptera: Tortricidae).
PubMed:Broad-spectrum insecticide resistance in obliquebanded leafroller Choristoneura rosaceana (Lepidoptera: Tortricidae) from Michigan.
PubMed:Evaluation of tebufenozide carry-over and residual effects on spruce budworm (Lepidoptera: Tortricidae).
PubMed:Molecular cloning and induction of nuclear receptors from insect cell lines.
PubMed:Pro-active management of beet armyworm (Lepidoptera: Noctuidae) resistance to tebufenozide and methoxyfenozide: baseline monitoring, risk assessment, and isolation of resistance.
PubMed:Toxicity, persistence, and efficacy of indoxacarb on cabbage looper (Lepidoptera: Noctuidae) on cabbage.
PubMed:Restriction of nutrient intake results in the increase of a specific Manduca sexta allatotropin (Manse-AT) mRNA in the larval nerve cord.
PubMed:Selection, egg viability, and fecundity of the sugarcane borer (Lepidoptera: Crambidae) with tebufenozide.
PubMed:Susceptibility of Diatraea saccharalis (Lepidoptera: Crambidae) to tebufenozide.
PubMed:Effect of RH-5992 on adult development in the spruce budworm, Choristoneura fumiferana.
PubMed:Action of brassinosteroids in the cotton leafworm Spodoptera littoralis.
PubMed:Comparative toxicity and ecdysone receptor affinity of non-steroidal ecdysone agonists and 20-hydroxyecdysone in Chironomus tentans.
PubMed:Inhibition of [3H]ponasterone A binding by ecdysone agonists in the intact Kc cell line.
PubMed:Dual ecdysteroid action on the epitracheal glands and central nervous system preceding ecdysis of Manduca sexta.
PubMed:Mode of action of the ecdysone agonist tebufenozide (RH-5992), and an exclusion mechanism to explain resistance to it.
PubMed:Quantitative structure-activity studies of insect growth regulators: XVIII. Effects of substituents on the aromatic moiety of dibenzoylhydrazines on larvicidal activity against the Colorado potato beetle Leptinotarsa decemlineata.
PubMed:Periodic expression of an ecdysteroid-induced nuclear receptor in a lepidopteran cell line (IAL-PID2).
PubMed:Apple damage, pest phenology, and factors influencing the efficacy of tebufenozide for control of obliquebanded leafroller (Lepidoptera: Tortricidae).
PubMed:The ABC transporter Pdr5p mediates the efflux of nonsteroidal ecdysone agonists in Saccharomyces cerevisiae.
PubMed:Effects of the hormone mimetic insecticide tebufenozide on Chironomus riparius larvae in two different exposure setups.
PubMed:Effects of field applied residues and length of exposure to tebufenozide on the obliquebanded leafroller (Lepidoptera: Tortricidae).
PubMed:Significance of absorption, oxidation, and binding to toxicity of four ecdysone agonists in multi-resistant cotton leafworm.
PubMed:Lethal and sublethal effects of insecticide residues on Orius insidiosus (Hemiptera: Anthocoridae) and Geocoris punctipes (Hemiptera: Lygaeidae).
PubMed:Baseline monitoring of codling moth (Lepidoptera: Tortricidae) larval response to benzoylhydrazine insecticides.
PubMed:Effects of a broad spectrum and biorational insecticides on parasitoids of the Nantucket pine tip moth (Lepidoptera: Tortricidae).
PubMed:RH-5992--an ecdysone agonist on model system of the silkworm Bombyx mori.
PubMed:Synergism of tebufenozide in resistant and susceptible strains of obliquebanded leafroller (Lepidoptera: Tortricidae) and resistance to new insecticides.
PubMed:Tebufenozide targeted against codling moth (Lepidoptera: Tortricidae) adults, eggs, and larvae.
PubMed:Developmental expression and stress induction of glutathione S-transferase in the spruce budworm, Choristoneura fumiferana.
PubMed:Inhibition of [(3)H]ponasterone a binding by ecdysone agonists in the intact Sf-9 cell line.
PubMed:Establishment and characterization of an Ostrinia nubilalis cell line, and its response to ecdysone agonists.
PubMed:Effect of insecticides on the diamondback moth (Lepidoptera: Plutellidae) and its parasitoid Diadegma insulare (Hymenoptera: Ichneumonidae).
PubMed:Effect of insecticides on Trichogramma exiguum (Trichogrammatidae: Hymenoptera) preimaginal development and adult survival.
PubMed:Biological activity of two juvenoids and two ecdysteroids against three stored product insects.
PubMed:Characterization of subclones of the epithelial cell line from Chironomus tentans resistant to the insecticide RH 5992, a non-steroidal moulting hormone agonist.
PubMed:Lethal and sublethal effects of selected insecticides and an insect growth regulator on the boll weevil (Coleoptera: Curculionidae) ectoparasitoid Catolaccus grandis (Hymenoptera: Pteromalidae).
PubMed:Relationships between structure and molting hormonal activity of tebufenozide, methoxyfenozide, and their analogs in cultured integument system of Chilo suppressalis Walker.
PubMed:Effect of bisacylhydrazine ecdysteroid mimics (RH-5849 and RH-5992) on chromosomal puffing, imaginal disc proliferation and pupariation in larvae of Drosophila melanogaster.
PubMed:Ecdysone agonist inducible transcription in transgenic tobacco plants.
PubMed:Ordination of zooplankton community data to detect pesticide effects in pond enclosures
PubMed:Activation of neuroblast proliferation in explant culture of the Drosophila larval CNS.
PubMed:Osmotic effects as a factor modifying insecticide toxicity on Aedes and Artemia.
PubMed:Basis for selective action of a synthetic molting hormone agonist, RH-5992 on lepidopteran insects.
PubMed:High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor.
PubMed:Ecdysteroid resistant subclones of the epithelial cell line from Chironomus tentans (Insecta, Diptera). I. Selection and characterization of resistant clones.
PubMed:Juvenile hormone acid: evidence for a hormonal function in induction of vitellogenin in larvae of Manduca sexta.
PubMed:New insecticides with ecdysteroidal and juvenile hormone activity.
PubMed:Molting hormonal and larvicidal activities of aliphatic acyl analogs of dibenzoylhydrazine insecticides.
PubMed:26-hydroxylation of ecdysteroids is catalyzed by a typical cytochrome P-450-dependent oxidase and related to ecdysteroid resistance in an insect cell line.
PubMed:The effects of several ecdysteroids and ecdysteroid agonists on two Drosophila imaginal disc cell lines.
PubMed:Ultrastructural Effects of a Non-Steroidal Ecdysone Agonist, RH-5992, on the Sixth Instar Larva of the Spruce Budworm, Choristoneura fumiferana.
PubMed:Characterization and partial cloning of ecdysteroid receptor from a cotton boll weevil embryonic cell line.
PubMed:Cloning and characterization of a new isoform of Choristoneura hormone receptor 3 from the spruce budworm.
PubMed:Cloning and development expression of Choristoneura hormone receptor 75: a homologue of the Drosophila E75A gene.
PubMed:Synapse loss and axon retraction in response to local muscle degeneration.
PubMed:Cloning and developmental expression of Choristoneura hormone receptor 3, an ecdysone-inducible gene and a member of the steroid hormone receptor superfamily.
PubMed:Steroid control of muscle remodeling during metamorphosis in Manduca sexta.
PubMed:Safety testing of tebufenozide, a new molt-inducing insecticide, for effects on nontarget forest soil invertebrates.
PubMed:Effects of a new molt-inducing insecticide, tebufenozide, on zooplankton communities in lake enclosures.
PubMed:Cloning and developmental expression of the ecdysone receptor gene from the spruce budworm, Choristoneura fumiferana.
PubMed:Toxicity of a new molt-inducing insecticide (RH-5992) to aquatic macroinvertebrates.
PubMed:Liquid chromatographic determination of RH-5992, an ecdysone agonist, in some forestry matrixes.
 
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