Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
intravenous-dog LDLo 20 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
unreported-guinea pig LD50 1200 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
intraperitoneal-mouse LD50 113 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
intraperitoneal-mouse LD50 195 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
intraperitoneal-mouse LD50 700 mg/kg BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
intraperitoneal-mouse LD50 3600 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
unreported-mouse LD50 4255 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
intraperitoneal-rat LD50 230 uL/kg Union Carbide Data Sheet. Vol. 7/23/1970
intraperitoneal-rat LD50 460 uL/kg Union Carbide Data Sheet. Vol. 10/16/1973
intraperitoneal-rat LD50 4470 mg/kg BEHAVIORAL: TREMOR AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951.
intravenous-rat LD50 100 uL/kg Union Carbide Data Sheet. Vol. 7/23/1970
intravenous-rat LD50 200 uL/kg Union Carbide Data Sheet. Vol. 10/16/1973
intravenous-rat LD50 710 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: TREMOR AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951.
oral-rat LD50 35600 uL/kg Union Carbide Data Sheet. Vol. 3/27/1969
oral-rat LD50 56600 uL/kg Union Carbide Data Sheet. Vol. 3/28/1969
oral-rat LD50 > 2000 mg/kg Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl
oral-rat LD50 2150 mg/kg Union Carbide Data Sheet. Vol. 7/23/1970
oral-rat LD50 2410 mg/kg Union Carbide Data Sheet. Vol. 10/16/1973
oral-rat LD50 3750 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
oral-rat LD50 4190 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986.
oral-rat LD50 7250 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986.
oral-rat LD50 9760 mg/kg Union Carbide Data Sheet. Vol. 5/19/1960
oral-rat LD50 10334 mg/kg Dow Chemical Company Reports. Vol. MSD-395
oral-rat LD50 14800 mg/kg "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
oral-rat LD50 > 15000 mg/kg Dow Chemical Company Reports. Vol. MSD-508
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Dermal Toxicity: |
skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 3/20/1973
skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 10/16/1973
skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 7/23/1970
skin-rabbit LD50 > 20 mL/kg Union Carbide Data Sheet. Vol. 5/19/1960
skin-rabbit LD50 20 mL/kg Union Carbide Data Sheet. Vol. 3/27/1969
skin-rabbit LD50 20 mL/kg Union Carbide Data Sheet. Vol. 3/28/1969
skin-rabbit LD50 > 10000 mg/kg Dow Chemical Company Reports. Vol. MSD-95
skin-rabbit LD50 > 30000 mg/kg Dow Chemical Company Reports. Vol. MSD-395
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | cosmetic ingredient for skin conditioning |
Recommendation for ppg-7 usage levels up to: | | not for fragrance use.
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Recommendation for ppg-7 flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2-(2- | hydroxypropoxy)propan-1-ol (ppg-7) | | poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy- (7 mol PO average molar ratio) | | polyoxypropylene (7) | | polypropylene glycol (7) |
Articles:
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