EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

piperazine adipate
hexanedioic acid, compd. with piperazine (1:1)

Supplier Sponsors

CAS Number: 142-88-1Picture of molecule3D/inchi
Other(deleted CASRN):93505-75-0
ECHA EINECS - REACH Pre-Reg:205-569-0
FDA UNII: V7P5P122LB
MDL:MFCD00050650
Molecular Weight:232.28020000
Formula:C10 H20 N2 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 338.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000018 mmHg @ 25.00 °C. (est)
Flash Point: 343.00 °F. TCC ( 172.70 °C. ) (est)
logP (o/w): 0.079 (est)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Piperazine adipate >98.0%
Maypro Industries
Piperazine Adipate
Santa Cruz Biotechnology
For experimental / research use only.
Piperazine Adipate
Sigma-Aldrich
For experimental / research use only.
Piperazine Adipate
European Pharmacopoeia (EP) Reference Standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 1640 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.

oral-mouse LD50 8000 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.

oral-rat LD50 7900 mg/kg
Annales Pharmaceutiques Francaises. Vol. 13, Pg. 539, 1955.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for piperazine adipate usage levels up to:
 not for fragrance use.
 
Recommendation for piperazine adipate flavor usage levels up to:
 not for flavor use.
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):142-88-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8905
National Institute of Allergy and Infectious Diseases:Data
hexanedioic acid;piperazine
Chemidplus:0000142881
EPA/NOAA CAMEO:hazardous materials
 
References:
 hexanedioic acid;piperazine
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):8905
Pubchem (sid):134973413
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):C13811
HMDB (The Human Metabolome Database):Search
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 adipic acid, compd. with piperazine (1:1) (8CI)
 adiprazina
 adiprazine
 arduvermin
 camin AP
 dietelmin
 divermex
 helmirazin
 hexanedioic acid - piperazine (1:1)
 hexanedioic acid compd. with piperazine (1:1)
 hexanedioic acid, compd. with piperazine (1:1)
 hexanedioic acid;piperazine
 nometan
 oxurasin
 oxypaat
 oxyzin
 pipadox
 piperascat
 piperaskat
 piperazine, monoadipate
 vermicompren
 vermilass
 

Articles:

Google Patents:Piperazine adipate compositions and treatment of helminth infections therewith
PubMed:Studies on the control of Toxocara canis in breeding kennels.
PubMed:Comparative anthelminthic efficacy and safety of Caesalpinia crista seed and piperazine adipate in chickens with artificially induced Ascaridia galli infection.
PubMed:Study of the acetylcholinesterase activity of Ascaridia galli: kinetic properties and the effect of anthelmintics.
PubMed:[Immunomodulation in patients with cavernous kidney tuberculosis using piperazine adipinate and amniocene].
PubMed:[Experience with the prevention of enterobiasis in children from preschool institutions of the Zhitomir district].
PubMed:[Cleft hand and cleft foot abnormalities as a possible teratogenic side effect of the anthelmintic piperazine?].
PubMed:The effect of piperazine adipate and parbendazole on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae.
PubMed:Effect of parbendazole and piperazine adipate on the activity of some enzymes of Ascaridia galli and Heterakis gallinae.
PubMed:A comparison of the genetic activity of pyrvinium pamoate with that of several other anthelmintic drugs in Saccharomyces cerevisiae.
PubMed:Integumentomuscular sac of Ascaris lumbricoides suis L: a biomembrane for studies on the transport of chemical substances.
PubMed:[Effectiveness and influence of piperazine adipinate on the immunological indices of furunculosis patients].
PubMed:Investigations of anthelminthic activity and synthesis of new derivatives of perhydroazepine, perhydro-1,4-diazepine, perhydro-1,4-oxazepine and perhydro-1,5-oxazocine.
PubMed:[Study of compounds with potential antiparasitic effect. V. Antihistaminics].
PubMed:Acute transitory cerebellar dysfunction associated with piperazine adipate.
PubMed:Application of the isotope technique in pharmacodynamic analysis of penetration of drugs into parasites.
PubMed:Pyrantel embonate in mass treatment of ascariasis and comparison with piperazine adipate and santonin-kainic acid complex.
PubMed:[Usefulness of idalbin and piperazine adipate in the treatment of enterobiasis in children].
PubMed:Piperazine adipate in tropical eosinophilia--a preliminary study.
PubMed:[Drug control of eelworm in the domestic chicken, using piperazine adipate, with special reference to laying performance].
PubMed:[Control of ascriasis in the domestic fowl by use of piperazine adipate--with special reference to laying performance].
PubMed:[Tetramizole and piperazine adipate in the treatment of pigs infected with intestinal nematodes].
PubMed:[Contribution to the study of infestations with Ascaris lumbricoides in rural environments under the influence of mass helminthiasis control with piperazine adipate (Nematocton)].
PubMed:[Contribution to the study of the mass treatment of ascariasis with a single dose of piperazine adipate (Nematocton)].
PubMed:[THE NEUROTOXIC SIDE-EFFECTS OF PIPERAZINE DERIVATIVES STUDIED BY EEG IN CHILDREN. II. PIPERAZINE-ADIPATE, SHORT TREATMENT, PYRIDOXINE PROPHYLAXIS].
PubMed:Treatment of female mice and their litters with piperazine adipate in the drinking water.
PubMed:[Clinical trials of an anthelmintic: piperazine adipate].
PubMed:Studies on the action of cortisone administered with dithiazanine or with piperazine adipate on the course of the invasion with Trichinella spiralis (Owen, 1835) in white mice.
PubMed:[Considerations on the problem of piperazine adipate therapy of certain parasitic diseases of the digestive tract].
PubMed:[Changes in blood proteins in silver foxes during the administration of therapeutic portions of piperazine adipate and ethylene tetrachloride].
PubMed:[Effect of piperazine adipate on the growth of Trichomonas vaginalis Donne, 1836, on T. Vaginalis isolated from male urethras and on T. intestinalis (hominis) Leuckart, 1879].
PubMed:[Therapy of experimental trichinosis in rats with piperazine adipate and atabrine].
PubMed:[Examinations on the effectiveness of Hungarian made piperazine adipate against Enterobius vermicularis and Ascaris lumbricoides].
PubMed:Treatment of roundworm (Ascaris, Ancylostoma and Trichostrongylus) infections with piperazine adipate.
PubMed:[Piperazine adipate and phosphate in control of ascariasis in foxes].
PubMed:[Treatment of ascariasis with piperazine adipate; preliminary report].
PubMed:Treatment of ascariasis in children with piperazine adipate and thiocarbanilate.
PubMed:[The use of piperazine adipate for the mass treatment of ascariasis].
PubMed:[Clinical experience with piperazine adipate (vermofrik tablets) in ascariasis].
PubMed:[Effect of piperazine adipate on Enterobius vermicularis & Ascaris lumbricoides].
PubMed:[Comparative results of the use of piperazine-adipate and oxygen in the treatment of ascariasis].
PubMed:[Treatment of oxyuriasis in children with piperazine adipate].
PubMed:Mass therapy with piperazine adipate in the control of threadworm infestations.
PubMed:The use of piperazine adipate in ascariasis of captive zebras.
PubMed:Treatment of ascariasis in children with piperazine adipate.
PubMed:[Piperazine adipate in therapy of oxyuriasis].
PubMed:On the anthelmintic efficacy of piperazine adipate.
PubMed:[Forty cases of ascariasis treated with piperazine adipate].
PubMed:Preliminary trials with piperazine adipate as a veterinary anthelmintic.
PubMed:Piperazine adipate: a new anthelmintic agent. II. Toxicological and pharmacological studies.
PubMed:Piperazine adipate: a new anthelmintic agent. I. Physiochemical properties.
PubMed:[Piperazine adipate in the treatment of ascariasis and oxyuriasis].
 
Notes:
None found
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