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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 908.84 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 562.00 °F. TCC ( 294.70 °C. ) (est)
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| logP (o/w): | 0.077 (est) |
| Soluble in: |
| | water, 82.99 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 > 5000 mg/kg
Farmaco, Edizione Scientifica. Vol. 35, Pg. 3, 1980.
oral-mouse LD50 > 5000 mg/kg
Farmaco, Edizione Scientifica. Vol. 35, Pg. 3, 1980.
intraperitoneal-rat LD50 > 5000 mg/kg
Farmaco, Edizione Scientifica. Vol. 35, Pg. 3, 1980.
oral-rat LD50 > 5000 mg/kg
Farmaco, Edizione Scientifica. Vol. 35, Pg. 3, 1980.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for verbascoside usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for verbascoside flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :5281800 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
| Chemidplus:0061276173 |
| RTECS:LZ5786000 for cas# 61276-17-3 |
References:
| | [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5281800 |
| Pubchem (sid): | 135031461 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acteoside | | [(2R,3R,4R,5R,6R)-6-[2-(3,4- | dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
Articles:
| PubMed:Effect of dietary extruded linseed, verbascoside and vitamin E supplements on yield and quality of milk in Lacaune ewes. |
| PubMed:Bioactivity and phenolic composition from natural fermented table olives. |
| PubMed:Pro-Oxidative Action of Polyphenols as Action Mechanism for their Pro-Apoptotic Activity. |
| PubMed:Corneal epithelial wound healing promoted by verbascoside-based liposomal eyedrops. |
| PubMed:Gastroprotection as an example: antiadhesion against Helicobacter pylori, anti-inflammatory and antioxidant activities of aqueous extracts from the aerial parts of Lippia integrifolia Hieron. |
| PubMed:Inhibition of the DHT-induced PSA secretion by Verbascum xanthophoeniceum and Serenoa repens extracts in human LNCaP prostate epithelial cells. |
| PubMed:Influence of olive leaf processing on the bioaccessibility of bioactive polyphenols. |
| PubMed:Acylated phenylethanoid glycosides, echinacoside and acteoside from Cistanche tubulosa, improve glucose tolerance in mice. |
| PubMed:Prooxidant effects of verbascoside, a bioactive compound from olive oil mill wastewater, on in vitro developmental potential of ovine prepubertal oocytes and bioenergetic/oxidative stress parameters of fresh and vitrified oocytes. |
| PubMed:Ortho-diphenol profile and antioxidant activity of Algerian black olive cultivars: effect of dry salting process. |
| PubMed:Effects of verbascoside-based diet on blood and plasma constituents of rabbits. |
| PubMed:Inhibition of cholinesterase activity by extracts, fractions and compounds from Calceolaria talcana and C. integrifolia (Calceolariaceae: Scrophulariaceae). |
| PubMed:Inhibition of cholinesterase activity by extracts, fractions and compounds from Calceolaria talcana and C. integrifolia (Calceolariaceae: Scrophulariaceae). |
| PubMed:Anti-hyperglycemic and hypolipidemic effects of Cistanche tubulosa in type 2 diabetic db/db mice. |
| PubMed:Ocular tissues and fluids oxidative stress in hares fed on verbascoside supplement. |
| PubMed:Adsorption properties and preparative separation of phenylethanoid glycosides from Cistanche deserticola by use of macroporous resins. |
| PubMed:Acteoside: a lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha. |
| PubMed:Effect of long term dietary supplementation with plant extract on carcass characteristics meat quality and oxidative stability in pork. |
| PubMed:Identification and quantification of phytochemical composition and anti-inflammatory, cellular antioxidant, and radical scavenging activities of 12 Plantago species. |
| PubMed:Tyrosinase inhibitors from Calceolaria integrifolia s.l.: Calceolaria talcana aerial parts. |
| PubMed:A study of the precursors of the natural antioxidant phenol 3,4-dihydroxyphenylglycol in olive oil waste. |
| PubMed:Antioxidant activity of phenolic fractions in olive mill wastewater. |
| PubMed:Cellular mechanisms of the cytotoxic effects of the zearalenone metabolites α-zearalenol and β-zearalenol on RAW264.7 macrophages. |
| PubMed:Isolation and identification of phenolic glucosides from thermally treated olive oil byproducts. |
| PubMed:Changes in nitrosative stress biomarkers in swine intestine following dietary intervention with verbascoside. |
| PubMed:Separation, purification and quantification of verbascoside from Penstemon barbatus (Cav.) Roth. |
| PubMed:Phenolic antioxidants isolated from the flowers of Osmanthus fragrans. |
| PubMed:Chemical and antifungal investigations of six Lippia species (Verbenaceae) from Brazil. |
| PubMed:Aqueous extract of Anisomeles indica and its purified compound exerts anti-metastatic activity through inhibition of NF-κB/AP-1-dependent MMP-9 activation in human breast cancer MCF-7 cells. |
| PubMed:Feasible application of a portable NIR-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production. |
| PubMed:Cytotoxic and antioxidative activities of Plantago lagopus L. and characterization of its bioactive compounds. |
| PubMed:Verbascoside, isoverbascoside, and their derivatives recovered from olive mill wastewater as possible food antioxidants. |
| PubMed:Verbascoside is not genotoxic in the ST and HB crosses of the Drosophila wing spot test, and its constituent, caffeic acid, decreases the spontaneous mutation rate in the ST cross. |
| PubMed:Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé. |
| PubMed:Antioxidant and cholinesterases inhibitory activities of Verbascum xanthophoeniceum Griseb. and its phenylethanoid glycosides. |
| PubMed:Gamma irradiation of air-dried olive leaves: Effective decontamination and impact on the antioxidative properties and on phenolic compounds. |
| PubMed:Phenylethanoid glycosides as major antioxidants in Lippia multiflora herbal infusion and their stability during steam pasteurisation of plant material. |
| PubMed:Lemon verbena infusion consumption attenuates oxidative stress in dextran sulfate sodium-induced colitis in the rat. |
| PubMed:Jacaranda cuspidifolia Mart. (Bignoniaceae) as an antibacterial agent. |
| PubMed:Verbascosides from olive mill waste water: assessment of their bioaccessibility and intestinal uptake using an in vitro digestion/Caco-2 model system. |
| PubMed:Antinociceptive, free radical-scavenging, and cytotoxic activities of Acanthus hirsutus Boiss. |
| PubMed:Functional milk beverage fortified with phenolic compounds extracted from olive vegetation water, and fermented with functional lactic acid bacteria. |
| PubMed:Production of acteoside from Cistanche tubulosa by β-glucosidase. |
| PubMed:The antioxidant activity and thermal stability of lemon verbena (Aloysia triphylla) infusion. |
| PubMed:Harpagoside variation is positively correlated with temperature in Scrophularia ningpoensis Hemsl. |
| PubMed:Cultivar effect on the phenolic composition and antioxidant potential of stoned table olives. |
| PubMed:Acteoside inhibits PMA-induced matrix metalloproteinase-9 expression via CaMK/ERK- and JNK/NF-κB-dependent signaling. |
| PubMed:Biological activity of high molecular weight phenolics from olive mill wastewater. |
| PubMed:[Effects of phenylethanoid glycosides from seeds of Plantago asiatica on maturation of dendritic cells]. |
| PubMed:Acteoside and 6-O-acetylacteoside downregulate cell adhesion molecules induced by IL-1beta through inhibition of ERK and JNK in human vascular endothelial cells. |
| PubMed:Purification and characterization of an olive fruit beta-glucosidase involved in the biosynthesis of virgin olive oil phenolics. |
| PubMed:Effect of phenylethanoid glycosides and polysaccharides from the seed of Plantago asiatica L. on the maturation of murine bone marrow-derived dendritic cells. |
| PubMed:3,4-Dihydroxyphenylglycol (DHPG): an important phenolic compound present in natural table olives. |
| PubMed:Impact of sampling parameters on the radical scavenging potential of olive (Olea europaea L.) leaves. |
| PubMed:Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach. |
| PubMed:Compositional and tissue modifications induced by the natural fermentation process in table olives. |
| PubMed:Antioxidative activity of the flower of Torenia fournieri. |
| PubMed:Verminoside- and verbascoside-induced genotoxicity on human lymphocytes: involvement of PARP-1 and p53 proteins. |
| PubMed:Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts. |
| PubMed:HPLC-DAD-ESI-MS analysis of the constituents of aqueous preparations of verbena and lemon verbena and evaluation of the antioxidant activity. |
| PubMed:Inhibition of inducible nitric oxide synthase in vitro and in vivo by a water-soluble extract of Wendita calysina leaves. |
| PubMed:Small branches of olive tree: a source of biophenols complementary to olive leaves. |
| PubMed:Static-dynamic superheated liquid extraction of hydroxytyrosol and other biophenols from alperujo (a semisolid residue of the olive oil industry). |
| PubMed:Bioscreening of Australian olive mill waste extracts: biophenol content, antioxidant, antimicrobial and molluscicidal activities. |
| PubMed:Table olives from Portugal: phenolic compounds, antioxidant potential, and antimicrobial activity. |
| PubMed:Changes in phenolic composition induced by Pseudomonas savastanoi pv. Savastanoi infection in olive tree: presence of large amounts of verbascoside in nodules of tuberculosis disease. |
| PubMed:The use of Lactobacillus pentosus 1MO to shorten the debittering process time of black table olives (Cv. Itrana and Leccino): a pilot-scale application. |
| PubMed:Storage of olives (Olea europaea L.) under CO2 atmosphere: liquid chromatography-mass spectrometry characterization of indices related to changes in polyphenolic metabolism. |
| PubMed:Investigation of Australian olive mill waste for recovery of biophenols. |
| PubMed:Solid olive residues: insight into their phenolic composition. |
| PubMed:Phenylpropanoid glycosides from Tynanthus panurensis: characterization and LC-MS quantitative analysis. |
| PubMed:Nondestructive evaluation of anthocyanins in olive (Olea europaea) fruits by in situ chlorophyll fluorescence spectroscopy. |
| PubMed:Polyphenol changes during fermentation of naturally black olives. |
| PubMed:Methanolic extract of Verbascum macrurum as a source of natural preservatives against oxidative rancidity. |
| PubMed:Isolation, structure elucidation and antioxidant potential of the major phenolic and flavonoid compounds in brined olive drupes. |
| PubMed:Radioprotective effects in vivo of phenolics extracted from Olea europaea L. leaves against X-ray-induced chromosomal damage: comparative study versus several flavonoids and sulfur-containing compounds. |
| PubMed:Changes in the concentrations of bioactive compounds in plantain leaves. |
| PubMed:Analytical method for Buddleja colorants in foods. |
| PubMed:Antioxidative activities of phenylethanoid glycosides from Ligustrum purpurascens. |
| PubMed:Polyphenolic content in five tuscany cultivars of Olea europaea L. |
| PubMed:Phenolic compounds of olive fruit: one- and two-dimensional nuclear magnetic resonance characterization of Nüzhenide and its distribution in the constitutive parts of fruit. |
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3D/inchi